L1 retrotransposition occurs mainly in embryogenesis and creates somatic mosaicism

Genes and Development

Volumn 23, Issue 11, 2009, Pages 1303-1312

  Kano, Hiroki ^a   Godoy, Irene ^a   Courtney, Christine ^a   Vetter, Melissa R ^a   Gerton, George L ^a   Ostertag, Eric M ^b   Kazazian Jr , Haig H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Transposagen Biopharmaceuticals Inc   (United States)

Author keywords

Line 1; Retrotransposon; RNA carryover; Somatic mosaicism

Indexed keywords

GENOMIC DNA; RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA TRANSPOSITION; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; GENOTYPE; GERM CELL; LONG INTERSPERSED ELEMENT 1; LONG INTERSPERSED REPEAT; MALE; MOSAICISM; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RETROPOSON; TISSUE SPECIFICITY; TRANSGENIC MOUSE; TRANSGENIC RAT; ANIMAL; ANIMAL EMBRYO; C57BL MOUSE; GENETICS; GENOME; METABOLISM; PHYSIOLOGY; PRENATAL DEVELOPMENT; SPRAGUE DAWLEY RAT;

MAMMALIA; MUS MUSCULUS; RATTUS;

ANIMALS; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; FEMALE; GENOME; GENOTYPE; GERM CELLS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOSAICISM; RATS; RATS, SPRAGUE-DAWLEY; RATS, TRANSGENIC; RNA;

EID: 66149168927     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1803909     Document Type: Article

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