Mosaic loss of chromosome y in peripheral blood is associated with shorter survival and higher risk of cancer

Nature Genetics

Volumn 46, Issue 6, 2014, Pages 624-628

  Forsberg, Lars A ^a   Rasi, Chiara ^a   Malmqvist, Niklas ^a   Davies, Hanna ^a   Pasupulati, Saichand ^a   Pakalapati, Geeta ^a   Sandgren, Johanna ^b   De Ståhl, Teresita Diaz ^b   Zaghlool, Ammar ^a   Giedraitis, Vilmantas ^c   Lannfelt, Lars ^c   Score, Joannah ^d   Cross, Nicholas C P ^d   Absher, Devin ^e   Janson, Eva Tiensuu ^a   Lindgren, Cecilia M ^f,g   Morris, Andrew P ^f   Ingelsson, Erik ^a   Lind, Lars ^a   Dumanski, Jan P ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UPPSALA UNIVERSITY   (Sweden)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^e HUDSONALPHA INSTITUTE FOR BIOTECHNOLOGY   (United States)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER INCIDENCE; CANCER MORTALITY; CANCER RISK; CANCER SURVIVAL; CARCINOGENESIS; CHROMOSOME LOSS; CHROMOSOME MOSAICISM; HEMATOPOIETIC CELL; HUMAN; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; SEX DETERMINATION; SURVIVAL TIME; VERY ELDERLY; Y CHROMOSOME;

AGED; AGED, 80 AND OVER; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, Y; COHORT STUDIES; GENE DELETION; GENETIC VARIATION; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MOSAICISM; NEOPLASMS; PHENOTYPE; PROPORTIONAL HAZARDS MODELS; RISK; SEX FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 84901682843     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2966     Document Type: Article

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