-
1
-
-
84860338675
-
R loops: From transcription byproducts to threats to genome stability
-
Aguilera A, Garcia-Muse T. 2012. R loops: from transcription byproducts to threats to genome stability. Mol. Cell 46:115-24
-
(2012)
Mol. Cell
, vol.46
, pp. 115-124
-
-
Aguilera, A.1
Garcia-Muse, T.2
-
2
-
-
77956848635
-
Long-term restriction by APOBEC3F selects human immunodeficiency virus type 1 variants with restored Vif function
-
Albin JS, Hache G, Hultquist JF, Brown WL, Harris RS. 2010. Long-term restriction by APOBEC3F selects human immunodeficiency virus type 1 variants with restored Vif function. J. Virol. 84:10209-19
-
(2010)
J. Virol
, vol.84
, pp. 10209-10219
-
-
Albin, J.S.1
Hache, G.2
Hultquist, J.F.3
Brown, W.L.4
Harris, R.S.5
-
3
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, et al. 2013. Signatures of mutational processes in human cancer. Nature 500:415-21
-
(2013)
Nature
, vol.500
, pp. 415-421
-
-
Alexandrov, L.B.1
Nik-Zainal, S.2
Wedge, D.C.3
Aparicio, S.A.4
Behjati, S.5
-
4
-
-
84873186179
-
Deciphering signatures of mutational processes operative in human cancer
-
Alexandrov LB, Nik-Zainal S, Wedge DC, Campbell PJ, StrattonMR. 2013. Deciphering signatures of mutational processes operative in human cancer. Cell Rep. 3:246-59
-
(2013)
Cell Rep
, vol.3
, pp. 246-259
-
-
Alexandrov, L.B.1
Nik-Zainal, S.2
Wedge, D.C.3
Campbell, P.J.4
Stratton, M.R.5
-
5
-
-
84891102589
-
Mutational signatures: The patterns of somatic mutations hidden in cancer genomes
-
Alexandrov LB, Stratton MR. 2014. Mutational signatures: the patterns of somatic mutations hidden in cancer genomes. Curr. Opin. Genet. Dev. 24:52-60
-
(2014)
Curr. Opin. Genet. Dev
, vol.24
, pp. 52-60
-
-
Alexandrov, L.B.1
Stratton, M.R.2
-
6
-
-
84880284498
-
Footprint of APOBEC3 on the genome of human retroelements
-
Anwar F,DavenportMP, EbrahimiD. 2013. Footprint of APOBEC3 on the genome of human retroelements. J. Virol. 87:8195-204
-
(2013)
J. Virol
, vol.87
, pp. 8195-8204
-
-
Anwar, F.1
Davenport, M.P.2
Ebrahimi, D.3
-
7
-
-
84885023707
-
Neurospora crassa, a model system for epigenetics research
-
Aramayo R, Selker EU. 2013. Neurospora crassa, a model system for epigenetics research. Cold Spring Harb. Perspect. Biol. 5:a017921
-
(2013)
Cold Spring Harb. Perspect. Biol
, vol.5
, pp. a017921
-
-
Aramayo, R.1
Selker, E.U.2
-
8
-
-
84872649870
-
Retroelements versusAPOBEC3family members: No great escape from the magnificent seven
-
Arias JF,KoyamaT,KinomotoM,TokunagaK. 2012. Retroelements versusAPOBEC3family members: no great escape from the magnificent seven. Front. Microbiol. 3:275
-
(2012)
Front. Microbiol
, vol.3
, pp. 275
-
-
Arias, J.F.1
Koyama, T.2
Kinomoto, M.3
Tokunaga, K.4
-
9
-
-
84859636918
-
A fine-scale chimpanzee genetic map from population sequencing
-
Auton A, Fledel-Alon A, Pfeifer S, Venn O, Segurel L, et al. 2012. A fine-scale chimpanzee genetic map from population sequencing. Science 336:193-98
-
(2012)
Science
, vol.336
, pp. 193-198
-
-
Auton, A.1
Fledel-Alon, A.2
Pfeifer, S.3
Venn, O.4
Segurel, L.5
-
10
-
-
0030838612
-
Genetics and the origin of species: An introduction
-
Ayala FJ, Fitch WM. 1997. Genetics and the origin of species: an introduction. PNAS 94:7691-97
-
(1997)
PNAS
, vol.94
, pp. 7691-7697
-
-
Ayala, F.J.1
Fitch, W.M.2
-
11
-
-
84895784747
-
Mechanisms of base substitution mutagenesis in cancer genomes
-
Bacolla A, Cooper DN, Vasquez KM. 2014. Mechanisms of base substitution mutagenesis in cancer genomes. Genes 5:108-46
-
(2014)
Genes
, vol.5
, pp. 108-146
-
-
Bacolla, A.1
Cooper, D.N.2
Vasquez, K.M.3
-
12
-
-
0025309892
-
Frameshift errors initiated by nucleotide misincorporation
-
Bebenek K, Kunkel TA. 1990. Frameshift errors initiated by nucleotide misincorporation. PNAS 87:4946-50
-
(1990)
PNAS
, vol.87
, pp. 4946-4950
-
-
Bebenek, K.1
Kunkel, T.A.2
-
13
-
-
0000342704
-
Induction of specific mutations with 5-bromouracil
-
Benzer S, Freese E. 1958. Induction of specific mutations with 5-bromouracil. PNAS 44:112-19
-
(1958)
PNAS
, vol.44
, pp. 112-119
-
-
Benzer, S.1
Freese, E.2
-
14
-
-
58849161775
-
Hotspots of biased nucleotide substitutions in human genes
-
Berglund J, Pollard KS, WebsterMT. 2009. Hotspots of biased nucleotide substitutions in human genes. PLOS Biol. 7:e26
-
(2009)
PLOS Biol
, vol.7
, pp. e26
-
-
Berglund, J.1
Pollard, K.S.2
Webster, M.T.3
-
15
-
-
84892699941
-
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
-
Bolli N, Avet-Loiseau H, Wedge DC, Van Loo P, Alexandrov LB, et al. 2014. Heterogeneity of genomic evolution and mutational profiles in multiple myeloma. Nat. Commun. 5:2997
-
(2014)
Nat. Commun
, vol.5
, pp. 2997
-
-
Bolli, N.1
Avet-Loiseau, H.2
Wedge, D.C.3
Van Loo, P.4
Alexandrov, L.B.5
-
16
-
-
0034683726
-
Evidence that proximal multiple mutations in Big Blue transgenic mice are dependent events
-
Buettner VL, Hill KA, Scaringe WA, Sommer SS. 2000. Evidence that proximal multiple mutations in Big Blue transgenic mice are dependent events. Mutat. Res. 452:219-29
-
(2000)
Mutat. Res
, vol.452
, pp. 219-229
-
-
Buettner, V.L.1
Hill, K.A.2
Scaringe, W.A.3
Sommer, S.S.4
-
17
-
-
84857829246
-
Analysis of human accelerated DNA regions using archaic hominin genomes
-
Burbano HA, Green RE, Maricic T, Lalueza-Fox C, de la Rasilla M, et al. 2012. Analysis of human accelerated DNA regions using archaic hominin genomes. PLOS ONE 7:e32877
-
(2012)
PLOS ONE
, vol.7
, pp. e32877
-
-
Burbano, H.A.1
Green, R.E.2
Maricic, T.3
Lalueza-Fox, C.4
De La Rasilla, M.5
-
18
-
-
79953652263
-
Damage-induced localized hypermutability
-
Burch LH, Yang Y, Sterling JF, Roberts SA, Chao FG, et al. 2011. Damage-induced localized hypermutability. Cell Cycle 10:1073-85
-
(2011)
Cell Cycle
, vol.10
, pp. 1073-1085
-
-
Burch, L.H.1
Yang, Y.2
Sterling, J.F.3
Roberts, S.A.4
Chao, F.G.5
-
19
-
-
84874188583
-
APOBEC3B is an enzymatic source of mutation in breast cancer
-
Burns MB, Lackey L, Carpenter MA, Rathore A, Land AM, et al. 2013. APOBEC3B is an enzymatic source of mutation in breast cancer. Nature 494:366-70
-
(2013)
Nature
, vol.494
, pp. 366-370
-
-
Burns, M.B.1
Lackey, L.2
Carpenter, M.A.3
Rathore, A.4
Land, A.M.5
-
20
-
-
84883356320
-
Evidence for APOBEC3B mutagenesis in multiple human cancers
-
Burns MB, Temiz NA, Harris RS. 2013. Evidence for APOBEC3B mutagenesis in multiple human cancers. Nat. Genet. 45:977-83
-
(2013)
Nat. Genet
, vol.45
, pp. 977-983
-
-
Burns, M.B.1
Temiz, N.A.2
Harris, R.S.3
-
21
-
-
84868214089
-
Estimating the human mutation rate using autozygosity in a founder population
-
Campbell CD, Chong JX, Malig M, Ko A, Dumont BL, et al. 2012. Estimating the human mutation rate using autozygosity in a founder population. Nat. Genet. 44:1277-81
-
(2012)
Nat. Genet
, vol.44
, pp. 1277-1281
-
-
Campbell, C.D.1
Chong, J.X.2
Malig, M.3
Ko, A.4
Dumont, B.L.5
-
23
-
-
84855686649
-
Large-scale DNA editing of retrotransposons accelerates mammalian genome evolution
-
Carmi S, Church GM, Levanon EY. 2011. Large-scale DNA editing of retrotransposons accelerates mammalian genome evolution. Nat. Commun. 2:519
-
(2011)
Nat. Commun
, vol.2
, pp. 519
-
-
Carmi, S.1
Church, G.M.2
Levanon, E.Y.3
-
24
-
-
84923309215
-
A prevalent cancer susceptibility APOBEC3A hybrid allele bearing APOBEC3B 3-UTR enhances chromosomal DNA damage
-
Caval V, Suspene R, Shapira M, Vartanian JP,Wain-Hobson S. 2014. A prevalent cancer susceptibility APOBEC3A hybrid allele bearing APOBEC3B 3-UTR enhances chromosomal DNA damage. Nat. Commun. 5:5129
-
(2014)
Nat. Commun
, vol.5
, pp. 5129
-
-
Caval, V.1
Suspene, R.2
Shapira, M.3
Vartanian, J.P.4
Wain-Hobson, S.5
-
25
-
-
84887183068
-
The choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis
-
Chan K, Resnick MA, Gordenin DA. 2013. The choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis. DNA Repair (Amst.) 12:878-89
-
(2013)
DNA Repair (Amst. )
, vol.12
, pp. 878-889
-
-
Chan, K.1
Resnick, M.A.2
Gordenin, D.A.3
-
26
-
-
84940574759
-
An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers
-
Chan K, Roberts SA, Klimczak LJ, Sterling JF, Saini N, et al. 2015. An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers. Nat. Genet. 47(9):1067-72
-
(2015)
Nat. Genet
, vol.47
, Issue.9
, pp. 1067-1072
-
-
Chan, K.1
Roberts, S.A.2
Klimczak, L.J.3
Sterling, J.F.4
Saini, N.5
-
27
-
-
84872008477
-
Base damage within single-strand DNA underlies in vivo hypermutability induced by a ubiquitous environmental agent
-
Chan K, Sterling JF, Roberts SA, Bhagwat AS, Resnick MA, Gordenin DA. 2012. Base damage within single-strand DNA underlies in vivo hypermutability induced by a ubiquitous environmental agent. PLOS Genet. 8:e1003149
-
(2012)
PLOS Genet
, vol.8
, pp. e1003149
-
-
Chan, K.1
Sterling, J.F.2
Roberts, S.A.3
Bhagwat, A.S.4
Resnick, M.A.5
Gordenin, D.A.6
-
28
-
-
84899889433
-
Repair of naturally occurring mismatches can induce mutations in flanking DNA
-
Chen J, Miller BF, Furano AV. 2014. Repair of naturally occurring mismatches can induce mutations in flanking DNA. eLife 3:e02001
-
(2014)
ELife
, vol.3
, pp. e02001
-
-
Chen, J.1
Miller, B.F.2
Furano, A.V.3
-
29
-
-
56649109612
-
Epidemiology of doublet/multiplet mutations in lung cancers: Evidence that a subset arises by chronocoordinate events
-
Chen Z, Feng J, Buzin CH, Sommer SS. 2008. Epidemiology of doublet/multiplet mutations in lung cancers: evidence that a subset arises by chronocoordinate events. PLOS ONE 3:e3714
-
(2008)
PLOS ONE
, vol.3
, pp. e3714
-
-
Chen, Z.1
Feng, J.2
Buzin, C.H.3
Sommer, S.S.4
-
30
-
-
47549104067
-
EGFR somatic doublets in lung cancer are frequent and generally arise from a pair of driver mutations uncommonly seen as singlet mutations: One-third of doublets occur at five pairs of amino acids
-
Chen Z, Feng J, Saldivar JS, Gu D, Bockholt A, Sommer SS. 2008. EGFR somatic doublets in lung cancer are frequent and generally arise from a pair of driver mutations uncommonly seen as singlet mutations: one-third of doublets occur at five pairs of amino acids. Oncogene 27:4336-43
-
(2008)
Oncogene
, vol.27
, pp. 4336-4343
-
-
Chen, Z.1
Feng, J.2
Saldivar, J.S.3
Gu, D.4
Bockholt, A.5
Sommer, S.S.6
-
31
-
-
42649120310
-
The APOBEC3 cytidine deaminases: An innate defensive network opposing exogenous retroviruses and endogenous retroelements
-
Chiu YL,GreeneWC. 2008. The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements. Annu. Rev. Immunol. 26:317-53
-
(2008)
Annu. Rev. Immunol
, vol.26
, pp. 317-353
-
-
Chiu, Y.L.1
Greene, W.C.2
-
33
-
-
0037022293
-
The unexpected landscape of in vivo somatic mutation in a human epithelial cell lineage
-
Colgin LM, Hackmann AF, Emond MJ, Monnat RJ Jr. 2002. The unexpected landscape of in vivo somatic mutation in a human epithelial cell lineage. PNAS 99:1437-42
-
(2002)
PNAS
, vol.99
, pp. 1437-1442
-
-
Colgin, L.M.1
Hackmann, A.F.2
Emond, M.J.3
Monnat, R.J.4
-
35
-
-
84892743776
-
Break-induced replication repair of damaged forks induces genomic duplications in human cells
-
Costantino L, Sotiriou SK, Rantala JK, Magin S, Mladenov E, et al. 2014. Break-induced replication repair of damaged forks induces genomic duplications in human cells. Science 343:88-91
-
(2014)
Science
, vol.343
, pp. 88-91
-
-
Costantino, L.1
Sotiriou, S.K.2
Rantala, J.K.3
Magin, S.4
Mladenov, E.5
-
36
-
-
84908695210
-
The somatic genomic landscape of chromophobe renal cell carcinoma
-
Davis CF, Ricketts CJ, Wang M, Yang L, Cherniack AD, et al. 2014. The somatic genomic landscape of chromophobe renal cell carcinoma. Cancer Cell 26:319-30
-
(2014)
Cancer Cell
, vol.26
, pp. 319-330
-
-
Davis, C.F.1
Ricketts, C.J.2
Wang, M.3
Yang, L.4
Cherniack, A.D.5
-
37
-
-
79952273242
-
Break-induced replication is highly inaccurate
-
Deem A, Keszthelyi A, Blackgrove T, Vayl A, Coffey B, et al. 2011. Break-induced replication is highly inaccurate. PLOS Biol. 9:e1000594
-
(2011)
PLOS Biol
, vol.9
, pp. e1000594
-
-
Deem, A.1
Keszthelyi, A.2
Blackgrove, T.3
Vayl, A.4
Coffey, B.5
-
38
-
-
84886073963
-
Oxidative stress-induced mutagenesis in single-strand DNA occurs primarily at cytosines and is DNA polymerase zeta-dependent only for adenines and guanines
-
Degtyareva NP, Heyburn L, Sterling J, Resnick MA, Gordenin DA, Doetsch PW. 2013. Oxidative stress-induced mutagenesis in single-strand DNA occurs primarily at cytosines and is DNA polymerase zeta-dependent only for adenines and guanines. Nucleic Acids Res. 41:8995-9005
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 8995-9005
-
-
Degtyareva, N.P.1
Heyburn, L.2
Sterling, J.3
Resnick, M.A.4
Gordenin, D.A.5
Doetsch, P.W.6
-
39
-
-
84859724110
-
Similarities and differences between "uncapped" telomeres andDNAdoublestrand breaks
-
Dewar JM, Lydall D. 2012. Similarities and differences between "uncapped" telomeres andDNAdoublestrand breaks. Chromosoma 121:117-30
-
(2012)
Chromosoma
, vol.121
, pp. 117-130
-
-
Dewar, J.M.1
Lydall, D.2
-
41
-
-
0032808947
-
The distribution of rates of spontaneous mutation over viruses, prokaryotes, and eukaryotes
-
Drake JW. 1999. The distribution of rates of spontaneous mutation over viruses, prokaryotes, and eukaryotes. Ann. N. Y. Acad. Sci. 870:100-7
-
(1999)
Ann. N. Y. Acad. Sci
, vol.870
, pp. 100-107
-
-
Drake, J.W.1
-
42
-
-
34547740652
-
Too many mutants with multiple mutations
-
Drake JW. 2007. Too many mutants with multiple mutations. Crit. Rev. Biochem. Mol. Biol. 42:247-58
-
(2007)
Crit. Rev. Biochem. Mol. Biol
, vol.42
, pp. 247-258
-
-
Drake, J.W.1
-
43
-
-
34948890647
-
Biased clustered substitutions in the human genome: The footprints of male-driven biased gene conversion
-
Dreszer TR, Wall GD, Haussler D, Pollard KS. 2007. Biased clustered substitutions in the human genome: the footprints of male-driven biased gene conversion. Genome Res. 17:1420-30
-
(2007)
Genome Res
, vol.17
, pp. 1420-1430
-
-
Dreszer, T.R.1
Wall, G.D.2
Haussler, D.3
Pollard, K.S.4
-
44
-
-
44949198268
-
The impact of recombination on nucleotide substitutions in the human genome
-
DuretL,Arndt PF. 2008. The impact of recombination on nucleotide substitutions in the human genome. PLOS Genet. 4:e1000071
-
(2008)
PLOS Genet
, vol.4
, pp. e1000071
-
-
Duret, L.1
Arndt, P.F.2
-
45
-
-
84937191220
-
Genome-wide patterns and properties of de novo mutations in humans
-
Francioli LC, Polak PP, KorenA,MenelaouA,Chun S, et al. 2015. Genome-wide patterns and properties of de novo mutations in humans. Nat Genet. 47:822-26
-
(2015)
Nat Genet
, vol.47
, pp. 822-826
-
-
Francioli, L.C.1
Polak, P.P.2
Koren, A.3
Menelaou, A.4
Chun, S.5
-
46
-
-
0004228157
-
-
Washington, DC: ASM Press. 2nd ed
-
Friedberg E, Walker G, SiedeW,Wood R, Schultz R, EllenbergerT. 2005.DNARepair andMutagenesis. Washington, DC: ASM Press. 2nd ed
-
(2005)
DNARepair AndMutagenesis
-
-
Friedberg, E.1
Walker, G.2
Siede, W.3
Wood, R.4
Schultz, R.5
Ellenberger, T.6
-
47
-
-
85015066476
-
DNA damage and repair
-
Friedberg EC. 2003. DNA damage and repair. Nature 421:436-40
-
(2003)
Nature
, vol.421
, pp. 436-440
-
-
Friedberg, E.C.1
-
48
-
-
84859372986
-
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation
-
Fumagalli M, Rossiello F, Clerici M, Barozzi S, Cittaro D, et al. 2012. Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. Nat. Cell Biol. 14:355-65
-
(2012)
Nat. Cell Biol
, vol.14
, pp. 355-365
-
-
Fumagalli, M.1
Rossiello, F.2
Clerici, M.3
Barozzi, S.4
Cittaro, D.5
-
49
-
-
84898723553
-
Direct recognition of homology between double helices of DNA in Neurospora crassa
-
Gladyshev E, Kleckner N. 2014. Direct recognition of homology between double helices of DNA in Neurospora crassa. Nat. Comm. 5:3509
-
(2014)
Nat. Comm
, vol.5
, pp. 3509
-
-
Gladyshev, E.1
Kleckner, N.2
-
50
-
-
34347218988
-
Activation-induced cytidine deaminase action is strongly stimulated by mutations of the THO complex
-
Gomez-Gonzalez B, Aguilera A. 2007. Activation-induced cytidine deaminase action is strongly stimulated by mutations of the THO complex. PNAS 104:8409-14
-
(2007)
PNAS
, vol.104
, pp. 8409-8414
-
-
Gomez-Gonzalez, B.1
Aguilera, A.2
-
51
-
-
80053445930
-
Network models of TEM β-lactamase mutations coevolving under antibiotic selection show modular structure and anticipate evolutionary trajectories
-
Guthrie VB, Allen J, Camps M, Karchin R. 2011. Network models of TEM β-lactamase mutations coevolving under antibiotic selection show modular structure and anticipate evolutionary trajectories. PLOS Comput. Biol. 7:e1002184
-
(2011)
PLOS Comput. Biol
, vol.7
, pp. e1002184
-
-
Guthrie, V.B.1
Allen, J.2
Camps, M.3
Karchin, R.4
-
52
-
-
0034503096
-
DNA polymerase zeta introduces multiple mutations when bypassing spontaneous DNA damage in Saccharomyces cerevisiae
-
Harfe BD, Jinks-Robertson S. 2000. DNA polymerase zeta introduces multiple mutations when bypassing spontaneous DNA damage in Saccharomyces cerevisiae. Mol. Cell 6:1491-99
-
(2000)
Mol. Cell
, vol.6
, pp. 1491-1499
-
-
Harfe, B.D.1
Jinks-Robertson, S.2
-
53
-
-
0038681901
-
DNA deamination mediates innate immunity to retroviral infection
-
Harris RS, Bishop KN, Sheehy AM, Craig HM, Petersen-Mahrt SK, et al. 2003. DNA deamination mediates innate immunity to retroviral infection. Cell 113:803-9
-
(2003)
Cell
, vol.113
, pp. 803-809
-
-
Harris, R.S.1
Bishop, K.N.2
Sheehy, A.M.3
Craig, H.M.4
Petersen-Mahrt, S.K.5
-
55
-
-
0036863733
-
RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators
-
Harris RS, Petersen-Mahrt SK, Neuberger MS. 2002. RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators. Mol. Cell 10:1247-53
-
(2002)
Mol. Cell
, vol.10
, pp. 1247-1253
-
-
Harris, R.S.1
Petersen-Mahrt, S.K.2
Neuberger, M.S.3
-
56
-
-
84906303775
-
Mechanisms underlying mutational signatures in human cancers
-
Helleday T, Eshtad S, Nik-Zainal S. 2014. Mechanisms underlying mutational signatures in human cancers. Nat. Rev. Genet. 15:585-98
-
(2014)
Nat. Rev. Genet
, vol.15
, pp. 585-598
-
-
Helleday, T.1
Eshtad, S.2
Nik-Zainal, S.3
-
57
-
-
77954328102
-
Increased mutagenesis and unique mutation signature associated with mitotic gene conversion
-
Hicks WM, Kim M, Haber JE. 2010. Increased mutagenesis and unique mutation signature associated with mitotic gene conversion. Science 329:82-85
-
(2010)
Science
, vol.329
, pp. 82-85
-
-
Hicks, W.M.1
Kim, M.2
Haber, J.E.3
-
58
-
-
4344575833
-
Spontaneous multiple mutations show both proximal spacing consistent with chronocoordinate events and alterations with p53-deficiency
-
Hill KA,Wang J, Farwell KD, Scaringe WA, Sommer SS. 2004. Spontaneous multiple mutations show both proximal spacing consistent with chronocoordinate events and alterations with p53-deficiency. Mutat. Res. 554:223-40
-
(2004)
Mutat. Res
, vol.554
, pp. 223-240
-
-
Hill, K.A.1
Wang, J.2
Farwell, K.D.3
Scaringe, W.A.4
Sommer, S.S.5
-
59
-
-
30344440118
-
UracilDNAglycosylase is dispensable for human immunodeficiency virus type 1 replication and does not contribute to the antiviral effects of the cytidine deaminase APOBEC3G
-
Kaiser SM,Emerman M. 2006. UracilDNAglycosylase is dispensable for human immunodeficiency virus type 1 replication and does not contribute to the antiviral effects of the cytidine deaminase APOBEC3G. J. Virol. 80:875-82
-
(2006)
J. Virol
, vol.80
, pp. 875-882
-
-
Kaiser, S.M.1
Emerman, M.2
-
60
-
-
66749104393
-
High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer
-
Kashuba VI, Pavlova TV, Grigorieva EV, Kutsenko A, Yenamandra SP, et al. 2009. High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer. PLOS ONE 4:e5231
-
(2009)
PLOS ONE
, vol.4
, pp. e5231
-
-
Kashuba, V.I.1
Pavlova, T.V.2
Grigorieva, E.V.3
Kutsenko, A.4
Yenamandra, S.P.5
-
62
-
-
38349099227
-
Initiating the uninitiated: Replication of damaged DNA and carcinogenesis
-
Kaufmann WK. 2007. Initiating the uninitiated: replication of damaged DNA and carcinogenesis. Cell Cycle 6:1460-67
-
(2007)
Cell Cycle
, vol.6
, pp. 1460-1467
-
-
Kaufmann, W.K.1
-
65
-
-
0025779567
-
Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice
-
Kohler SW, Provost GS, Fieck A, Kretz PL, Bullock WO, et al. 1991. Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice. PNAS 88:7958-62
-
(1991)
PNAS
, vol.88
, pp. 7958-7962
-
-
Kohler, S.W.1
Provost, G.S.2
Fieck, A.3
Kretz, P.L.4
Bullock, W.O.5
-
66
-
-
84871174239
-
AID/APOBEC cytosine deaminase induces genome-wide kataegis
-
Lada AG, Dhar A, Boissy RJ, Hirano M, Rubel AA, et al. 2012. AID/APOBEC cytosine deaminase induces genome-wide kataegis. Biol. Direct 7:47
-
(2012)
Biol. Direct
, vol.7
, pp. 47
-
-
Lada, A.G.1
Dhar, A.2
Boissy, R.J.3
Hirano, M.4
Rubel, A.A.5
-
67
-
-
84884686754
-
Genome-wide mutation avalanches induced in diploid yeast cells by a base analog or an APOBEC deaminase
-
Lada AG, Stepchenkova EI,Waisertreiger ISR,NoskovVN, Dhar A, et al. 2013. Genome-wide mutation avalanches induced in diploid yeast cells by a base analog or an APOBEC deaminase. PLOS Genet. 9:e1003736
-
(2013)
PLOS Genet
, vol.9
, pp. e1003736
-
-
Lada, A.G.1
Stepchenkova, E.I.2
Waisertreiger, I.S.R.3
Noskov, V.N.4
Dhar, A.5
-
68
-
-
84880507665
-
Mutational heterogeneity in cancer and the search for new cancer-associated genes
-
Lawrence MS, Stojanov P, Polak P, Kryukov GV, Cibulskis K, et al. 2013. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature 499:214-18
-
(2013)
Nature
, vol.499
, pp. 214-218
-
-
Lawrence, M.S.1
Stojanov, P.2
Polak, P.3
Kryukov, G.V.4
Cibulskis, K.5
-
69
-
-
84869392858
-
Local and global functions of Timeless and Tipin in replication fork protection
-
Leman AR, Noguchi E. 2012. Local and global functions of Timeless and Tipin in replication fork protection. Cell Cycle 11:3945-55
-
(2012)
Cell Cycle
, vol.11
, pp. 3945-3955
-
-
Leman, A.R.1
Noguchi, E.2
-
70
-
-
0036640951
-
Human SNP variability and mutation rate are higher in regions of high recombination
-
Lercher MJ, Hurst LD. 2002. Human SNP variability and mutation rate are higher in regions of high recombination. Trends Genet. 18:337-40
-
(2002)
Trends Genet
, vol.18
, pp. 337-340
-
-
Lercher, M.J.1
Hurst, L.D.2
-
71
-
-
0028349973
-
Complex frameshift mutations mediated by plasmid pKM101: Mutational mechanisms deduced from 4-aminobiphenyl-induced mutation spectra in Salmonella
-
Levine JG, Schaaper RM, DeMarini DM. 1994. Complex frameshift mutations mediated by plasmid pKM101: mutational mechanisms deduced from 4-aminobiphenyl-induced mutation spectra in Salmonella. Genetics 136:731-46
-
(1994)
Genetics
, vol.136
, pp. 731-746
-
-
Levine, J.G.1
Schaaper, R.M.2
DeMarini, D.M.3
-
73
-
-
63149179802
-
Balancing AID and DNA repair during somatic hypermutation
-
Liu M, Schatz DG. 2009. Balancing AID and DNA repair during somatic hypermutation. Trends Immunol. 30:173-81
-
(2009)
Trends Immunol
, vol.30
, pp. 173-181
-
-
Liu, M.1
Schatz, D.G.2
-
74
-
-
84876585078
-
A common deletion in the APOBEC3 genes and breast cancer risk
-
Long J, Delahanty RJ, Li G, Gao YT, Lu W, et al. 2013. A common deletion in the APOBEC3 genes and breast cancer risk. J. Natl. Cancer Inst. 105:573-79
-
(2013)
J. Natl. Cancer Inst
, vol.105
, pp. 573-579
-
-
Long, J.1
Delahanty, R.J.2
Li, G.3
Gao, Y.T.4
Lu, W.5
-
75
-
-
41949120904
-
Apn1 and Apn2 endonucleases prevent accumulation of repairassociated DNA breaks in budding yeast as revealed by direct chromosomal analysis
-
Ma W, Resnick MA,Gordenin DA. 2008. Apn1 and Apn2 endonucleases prevent accumulation of repairassociated DNA breaks in budding yeast as revealed by direct chromosomal analysis. Nucleic Acids Res. 36:1836-46
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 1836-1846
-
-
Ma, W.1
Resnick, M.A.2
Gordenin, D.A.3
-
76
-
-
0000925644
-
Different rates of spontaneous mutation during mitosis and meiosis in yeast
-
Magni GE, Von Borstel RC. 1962. Different rates of spontaneous mutation during mitosis and meiosis in yeast. Genetics 47:1097-108
-
(1962)
Genetics
, vol.47
, pp. 1097-1108
-
-
Magni, G.E.1
Von Borstel, R.C.2
-
77
-
-
84870218426
-
Mutations arising during repair of chromosome breaks
-
Malkova A, Haber JE. 2012. Mutations arising during repair of chromosome breaks. Annu. Rev. Genet. 46:455-73
-
(2012)
Annu. Rev. Genet
, vol.46
, pp. 455-473
-
-
Malkova, A.1
Haber, J.E.2
-
78
-
-
84879887310
-
Break-induced replication: Functions and molecular mechanism
-
Malkova A, Ira G. 2013. Break-induced replication: functions and molecular mechanism. Curr. Opin. Genet. Dev. 23:271-79
-
(2013)
Curr. Opin. Genet. Dev
, vol.23
, pp. 271-279
-
-
Malkova, A.1
Ira, G.2
-
79
-
-
77953128777
-
The quest for molecular quasi-species in ligand-activity space and its application to directed enzyme evolution
-
Mannervik B, Runarsdottir A. 2010. The quest for molecular quasi-species in ligand-activity space and its application to directed enzyme evolution. FEBS Lett. 584:2565-71
-
(2010)
FEBS Lett
, vol.584
, pp. 2565-2571
-
-
Mannervik, B.1
Runarsdottir, A.2
-
80
-
-
0034720285
-
Low fidelity DNA synthesis by human DNA polymerase-eta
-
Matsuda T, Bebenek K, Masutani C, Hanaoka F, Kunkel TA. 2000. Low fidelity DNA synthesis by human DNA polymerase-eta. Nature 404:1011-13
-
(2000)
Nature
, vol.404
, pp. 1011-1013
-
-
Matsuda, T.1
Bebenek, K.2
Masutani, C.3
Hanaoka, F.4
Kunkel, T.A.5
-
81
-
-
77955964086
-
AID and somatic hypermutation
-
Maul RW, Gearhart PJ. 2010. AID and somatic hypermutation. Adv. Immunol. 105:159-91
-
(2010)
Adv. Immunol
, vol.105
, pp. 159-191
-
-
Maul, R.W.1
Gearhart, P.J.2
-
82
-
-
84871595000
-
Whole-genome sequencing in autism identifies hot spots for de novo germline mutation
-
Michaelson JJ, Shi Y, Gujral M, ZhengH,Malhotra D, et al. 2012. Whole-genome sequencing in autism identifies hot spots for de novo germline mutation. Cell 151:1431-42
-
(2012)
Cell
, vol.151
, pp. 1431-1442
-
-
Michaelson, J.J.1
Shi, Y.2
Gujral, M.3
Zheng, H.4
Malhotra, D.5
-
83
-
-
84857957437
-
Telomere proteins POT1, TRF1 and TRF2 augment long-patch base excision repair in vitro
-
Miller AS, Balakrishnan L, Buncher NA, Opresko PL, Bambara RA. 2012. Telomere proteins POT1, TRF1 and TRF2 augment long-patch base excision repair in vitro. Cell Cycle 11:998-1007
-
(2012)
Cell Cycle
, vol.11
, pp. 998-1007
-
-
Miller, A.S.1
Balakrishnan, L.2
Buncher, N.A.3
Opresko, P.L.4
Bambara, R.A.5
-
85
-
-
0035451450
-
Single nucleotide polymorphisms and recombination rate in humans
-
NachmanMW.2001. Single nucleotide polymorphisms and recombination rate in humans. Trends Genet. 17:481-85
-
(2001)
Trends Genet
, vol.17
, pp. 481-485
-
-
Nachman, M.W.1
-
86
-
-
84861541343
-
Mutational processes molding the genomes of 21 breast cancers
-
Nik-Zainal S, Alexandrov LB,Wedge DC, Van Loo P, Greenman CD, et al. 2012. Mutational processes molding the genomes of 21 breast cancers. Cell 149:979-93
-
(2012)
Cell
, vol.149
, pp. 979-993
-
-
Nik-Zainal, S.1
Alexandrov, L.B.2
Wedge, D.C.3
Van Loo, P.4
Greenman, C.D.5
-
87
-
-
84899645475
-
Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBECdependent mutations in breast cancer
-
Nik-Zainal S, Wedge DC, Alexandrov LB, Petljak M, Butler AP, et al. 2014. Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBECdependent mutations in breast cancer. Nat. Genet. 46:487-91
-
(2014)
Nat. Genet
, vol.46
, pp. 487-491
-
-
Nik-Zainal, S.1
Wedge, D.C.2
Alexandrov, L.B.3
Petljak, M.4
Butler, A.P.5
-
88
-
-
84891755888
-
DNA polymerases and Rev1 mediate error-prone bypass of non-B DNA structures
-
Northam MR, Moore EA, Mertz TM, Binz SK, Stith CM, et al. 2014. DNA polymerases and Rev1 mediate error-prone bypass of non-B DNA structures. Nucleic Acids Res. 42:290-306
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 290-306
-
-
Northam, M.R.1
Moore, E.A.2
Mertz, T.M.3
Binz, S.K.4
Stith, C.M.5
-
89
-
-
74249092035
-
Participation of DNA polymerase zeta in replication of undamaged DNA in Saccharomyces cerevisiae
-
Northam MR, Robinson HA, Kochenova OV, Shcherbakova PV. 2010. Participation of DNA polymerase zeta in replication of undamaged DNA in Saccharomyces cerevisiae. Genetics 184:27-42
-
(2010)
Genetics
, vol.184
, pp. 27-42
-
-
Northam, M.R.1
Robinson, H.A.2
Kochenova, O.V.3
Shcherbakova, P.V.4
-
90
-
-
0023115587
-
Simulating evolution by gene duplication
-
Ohta T. 1987. Simulating evolution by gene duplication. Genetics 115:207-13
-
(1987)
Genetics
, vol.115
, pp. 207-213
-
-
Ohta, T.1
-
91
-
-
73949105846
-
Use of high throughput sequencing to observe genome dynamics at a single cell level
-
Parkhomchuk D, Amstislavskiy V, Soldatov A, Ogryzko V. 2009. Use of high throughput sequencing to observe genome dynamics at a single cell level. PNAS 106:20830-35
-
(2009)
PNAS
, vol.106
, pp. 20830-20835
-
-
Parkhomchuk, D.1
Amstislavskiy, V.2
Soldatov, A.3
Ogryzko, V.4
-
92
-
-
79960220935
-
AID targeting in antibody diversity
-
Pavri R, Nussenzweig MC. 2011. AID targeting in antibody diversity. Adv. Immunol. 110:1-26
-
(2011)
Adv. Immunol
, vol.110
, pp. 1-26
-
-
Pavri, R.1
Nussenzweig, M.C.2
-
93
-
-
42649124572
-
The biochemistry of somatic hypermutation
-
Peled JU, Kuang FL, Iglesias-Ussel MD, Roa S, Kalis SL, et al. 2008. The biochemistry of somatic hypermutation. Annu. Rev. Immunol. 26:481-511
-
(2008)
Annu. Rev. Immunol
, vol.26
, pp. 481-511
-
-
Peled, J.U.1
Kuang, F.L.2
Iglesias-Ussel, M.D.3
Roa, S.4
Kalis, S.L.5
-
94
-
-
84918779420
-
AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature
-
Pettersen HS, Galashevskaya A, Doseth B, Sousa MM, Sarno A, et al. 2015. AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature. DNA Repair (Amst.) 25:60-71
-
(2015)
DNA Repair (Amst. )
, vol.25
, pp. 60-71
-
-
Pettersen, H.S.1
Galashevskaya, A.2
Doseth, B.3
Sousa, M.M.4
Sarno, A.5
-
95
-
-
1942439667
-
Switching from high-fidelity replicases to low-fidelity lesion-bypass polymerases
-
Plosky BS, Woodgate R. 2004. Switching from high-fidelity replicases to low-fidelity lesion-bypass polymerases. Curr. Opin. Genet. Dev. 14:113-19
-
(2004)
Curr. Opin. Genet. Dev
, vol.14
, pp. 113-119
-
-
Plosky, B.S.1
Woodgate, R.2
-
96
-
-
33750428182
-
Forces shaping the fastest evolving regions in the human genome
-
Pollard KS, Salama SR, King B, Kern AD, Dreszer T, et al. 2006. Forces shaping the fastest evolving regions in the human genome. PLOS Genet. 2:e168
-
(2006)
PLOS Genet
, vol.2
, pp. e168
-
-
Pollard, K.S.1
Salama, S.R.2
King, B.3
Kern, A.D.4
Dreszer, T.5
-
97
-
-
84899533639
-
Mutation signatures of carcinogen exposure: Genome-wide detection and new opportunities for cancer prevention
-
Poon S, McPherson J, Tan P, Teh B, Rozen S. 2014. Mutation signatures of carcinogen exposure: genome-wide detection and new opportunities for cancer prevention. Genome Med. 6:24
-
(2014)
Genome Med
, vol.6
, pp. 24
-
-
Poon, S.1
McPherson, J.2
Tan, P.3
Teh, B.4
Rozen, S.5
-
99
-
-
77953718211
-
Sequence space and the ongoing expansion of the protein universe
-
Povolotskaya IS, Kondrashov FA. 2010. Sequence space and the ongoing expansion of the protein universe. Nature 465:922-26
-
(2010)
Nature
, vol.465
, pp. 922-926
-
-
Povolotskaya, I.S.1
Kondrashov, F.A.2
-
100
-
-
84911431761
-
Recombination initiation maps of individual human genomes
-
Pratto F, Brick K, Khil P, Smagulova F, Petukhova GV, Camerini-Otero RD. 2014. Recombination initiation maps of individual human genomes. Science 346:6211
-
(2014)
Science
, vol.346
, pp. 6211
-
-
Pratto, F.1
Brick, K.2
Khil, P.3
Smagulova, F.4
Petukhova, G.V.5
Camerini-Otero, R.D.6
-
101
-
-
84919941546
-
B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity
-
Qian J, Wang Q, Dose M, Pruett N, Kieffer-KwonKR, et al. 2014. B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity. Cell 159:1524-37
-
(2014)
Cell
, vol.159
, pp. 1524-1537
-
-
Qian, J.1
Wang, Q.2
Dose, M.3
Pruett, N.4
Kieffer-Kwon, K.R.5
-
102
-
-
84908310298
-
APOBEC3 signature mutations in chronic lymphocytic leukemia
-
Rebhandl S, Huemer M, Gassner FJ, Zaborsky N, Hebenstreit D, et al. 2014. APOBEC3 signature mutations in chronic lymphocytic leukemia. Leukemia 28:1929-32
-
(2014)
Leukemia
, vol.28
, pp. 1929-1932
-
-
Rebhandl, S.1
Huemer, M.2
Gassner, F.J.3
Zaborsky, N.4
Hebenstreit, D.5
-
105
-
-
84899637671
-
APOBEC3A deaminates transiently exposed single-strand DNA during LINE-1 retrotransposition
-
Richardson SR, Narvaiza I, Planegger RA, Weitzman MD, Moran JV. 2014. APOBEC3A deaminates transiently exposed single-strand DNA during LINE-1 retrotransposition. eLife 3:e02008
-
(2014)
ELife
, vol.3
, pp. e02008
-
-
Richardson, S.R.1
Narvaiza, I.2
Planegger, R.A.3
Weitzman, M.D.4
Moran, J.V.5
-
106
-
-
0025630591
-
Frameshift mutation: Determinants of specificity
-
Ripley LS. 1990. Frameshift mutation: determinants of specificity. Annu. Rev. Genet. 24:189-213
-
(1990)
Annu. Rev. Genet
, vol.24
, pp. 189-213
-
-
Ripley, L.S.1
-
107
-
-
84896728239
-
Clustered and genome-wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitness
-
Roberts SA, Gordenin DA. 2014. Clustered and genome-wide transient mutagenesis in human cancers: hypermutation without permanent mutators or loss of fitness. BioEssays 36:382-93
-
(2014)
BioEssays
, vol.36
, pp. 382-393
-
-
Roberts, S.A.1
Gordenin, D.A.2
-
108
-
-
85019305142
-
Clustered mutations in human cancer
-
Roberts SA, Gordenin DA. 2014. Clustered mutations in human cancer. eLS doi: 10.1002/ 9780470015902.a0024941
-
(2014)
ELS
-
-
Roberts, S.A.1
Gordenin, D.A.2
-
109
-
-
84925497848
-
Hypermutation in human cancer genomes: Footprints andmechanisms
-
Roberts SA, Gordenin DA. 2014. Hypermutation in human cancer genomes: footprints andmechanisms. Nat. Rev. Cancer 14:786-800
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 786-800
-
-
Roberts, S.A.1
Gordenin, D.A.2
-
110
-
-
84883432724
-
An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers
-
Roberts SA, Lawrence MS, Klimczak LJ, Grimm SA, Fargo D, et al. 2013. An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers. Nat. Genet. 45:970-76
-
(2013)
Nat. Genet
, vol.45
, pp. 970-976
-
-
Roberts, S.A.1
Lawrence, M.S.2
Klimczak, L.J.3
Grimm, S.A.4
Fargo, D.5
-
111
-
-
84861460657
-
Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions
-
Roberts SA, Sterling J, Thompson C, Harris S, Mav D, et al. 2012. Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions. Mol. Cell 46:424-35
-
(2012)
Mol. Cell
, vol.46
, pp. 424-435
-
-
Roberts, S.A.1
Sterling, J.2
Thompson, C.3
Harris, S.4
Mav, D.5
-
112
-
-
77952396942
-
Human telomeres are hypersensitive to UV-induced DNA damage and refractory to repair
-
Rochette PJ, Brash DE. 2010. Human telomeres are hypersensitive to UV-induced DNA damage and refractory to repair. PLOS Genet. 6:e1000926
-
(2010)
PLOS Genet
, vol.6
, pp. e1000926
-
-
Rochette, P.J.1
Brash, D.E.2
-
113
-
-
0042847380
-
Theoretical analysis ofmutation hotspots and theirDNA sequence context specificity
-
Rogozin IB, Pavlov YI. 2003. Theoretical analysis ofmutation hotspots and theirDNA sequence context specificity. Mutat. Res. Rev. Mutat. 544:65-85
-
(2003)
Mutat. Res. Rev. Mutat
, vol.544
, pp. 65-85
-
-
Rogozin, I.B.1
Pavlov, Y.I.2
-
114
-
-
0035379581
-
Somatic mutation hotspots correlate with DNA polymerase ηerror spectrum
-
Rogozin IB, Pavlov YI, Bebenek K, Matsuda T, Kunkel TA. 2001. Somatic mutation hotspots correlate with DNA polymerase ηerror spectrum. Nat. Immunol. 2:530-36
-
(2001)
Nat. Immunol
, vol.2
, pp. 530-536
-
-
Rogozin, I.B.1
Pavlov, Y.I.2
Bebenek, K.3
Matsuda, T.4
Kunkel, T.A.5
-
115
-
-
84885843906
-
Migrating bubble during breakinduced replication drives conservative DNA synthesis
-
Saini N, Ramakrishnan S, Elango R, Ayyar S, Zhang Y, et al. 2013. Migrating bubble during breakinduced replication drives conservative DNA synthesis. Nature 502:389-92
-
(2013)
Nature
, vol.502
, pp. 389-392
-
-
Saini, N.1
Ramakrishnan, S.2
Elango, R.3
Ayyar, S.4
Zhang, Y.5
-
116
-
-
84902318918
-
Break-induced replication is a source of mutation clusters underlying kataegis
-
Sakofsky CJ, Roberts SA, Malc E, Mieczkowski PA, Resnick MA, et al. 2014. Break-induced replication is a source of mutation clusters underlying kataegis. Cell Rep. 7:1640-48
-
(2014)
Cell Rep
, vol.7
, pp. 1640-1648
-
-
Sakofsky, C.J.1
Roberts, S.A.2
Malc, E.3
Mieczkowski, P.A.4
Resnick, M.A.5
-
117
-
-
84874681638
-
Translesion DNA synthesis and mutagenesis in eukaryotes
-
Sale JE. 2013. Translesion DNA synthesis and mutagenesis in eukaryotes. Cold Spring Harb. Perspect. Biol. 5:a012708
-
(2013)
Cold Spring Harb. Perspect. Biol
, vol.5
, pp. a012708
-
-
Sale, J.E.1
-
118
-
-
40149102165
-
The DNA deaminase activity of human APOBEC3G is required for Ty1, MusD, and human immunodeficiency virus type 1 restriction
-
Schumacher AJ, Hache G, Macduff DA, BrownWL, Harris RS. 2008. The DNA deaminase activity of human APOBEC3G is required for Ty1, MusD, and human immunodeficiency virus type 1 restriction. J. Virol. 82:2652-60
-
(2008)
J. Virol
, vol.82
, pp. 2652-2660
-
-
Schumacher, A.J.1
Hache, G.2
Macduff, D.A.3
Brown, W.L.4
Harris, R.S.5
-
119
-
-
22244448696
-
APOBEC3G hypermutates genomic DNA and inhibits Ty1 retrotransposition in yeast
-
Schumacher AJ, Nissley DV, Harris RS. 2005. APOBEC3G hypermutates genomic DNA and inhibits Ty1 retrotransposition in yeast. PNAS 102:9854-59
-
(2005)
PNAS
, vol.102
, pp. 9854-9859
-
-
Schumacher, A.J.1
Nissley, D.V.2
Harris, R.S.3
-
120
-
-
33744546833
-
Translesion synthesis DNA polymerases and control of genome stability
-
Shcherbakova PV, Fijalkowska IJ. 2006. Translesion synthesis DNA polymerases and control of genome stability. Front. Biosci. 11:2496-517
-
(2006)
Front. Biosci
, vol.11
, pp. 2496-2517
-
-
Shcherbakova, P.V.1
Fijalkowska, I.J.2
-
121
-
-
84896845690
-
Complex correlations: Replication timing and mutational landscapes during cancer and genome evolution
-
Sima J, Gilbert DM. 2014. Complex correlations: replication timing and mutational landscapes during cancer and genome evolution. Curr. Opin. Genet. Dev. 25:93-100
-
(2014)
Curr. Opin. Genet. Dev
, vol.25
, pp. 93-100
-
-
Sima, J.1
Gilbert, D.M.2
-
122
-
-
0014935646
-
Natural selection and the concept of a protein space
-
Smith JM. 1970. Natural selection and the concept of a protein space. Nature 225:563-64
-
(1970)
Nature
, vol.225
, pp. 563-564
-
-
Smith, J.M.1
-
123
-
-
33749416027
-
The influence of recombination on human genetic diversity
-
Spencer CC, Deloukas P, Hunt S, Mullikin J, Myers S, et al. 2006. The influence of recombination on human genetic diversity. PLOS Genet. 2:e148
-
(2006)
PLOS Genet
, vol.2
, pp. e148
-
-
Spencer, C.C.1
Deloukas, P.2
Hunt, S.3
Mullikin, J.4
Myers, S.5
-
124
-
-
63449141981
-
Human mutation rate associated with DNA replication timing
-
Stamatoyannopoulos JA, Adzhubei I,Thurman RE,Kryukov GV,Mirkin SM, Sunyaev SR. 2009.Human mutation rate associated with DNA replication timing. Nat. Genet. 41:393-95
-
(2009)
Nat. Genet
, vol.41
, pp. 393-395
-
-
Stamatoyannopoulos, J.A.1
Adzhubei, I.2
Thurman, R.E.3
Kryukov, G.V.4
Mirkin, S.M.5
Sunyaev, S.R.6
-
125
-
-
57849133053
-
Mechanism of somatic hypermutation: Critical analysis of strand biased mutation signatures at A:T and G:C base pairs
-
Steele EJ. 2009. Mechanism of somatic hypermutation: critical analysis of strand biased mutation signatures at A:T and G:C base pairs. Mol. Immunol. 46:305-20
-
(2009)
Mol. Immunol
, vol.46
, pp. 305-320
-
-
Steele, E.J.1
-
126
-
-
84868677197
-
DNA polymerase zeta generates clustered mutations during bypass of endogenous DNA lesions in Saccharomyces cerevisiae
-
Stone JE, Lujan SA, Kunkel TA. 2012. DNA polymerase zeta generates clustered mutations during bypass of endogenous DNA lesions in Saccharomyces cerevisiae. Environ. Mol. Mutagen. 53:777-86
-
(2012)
Environ. Mol. Mutagen
, vol.53
, pp. 777-786
-
-
Stone, J.E.1
Lujan, S.A.2
Kunkel, T.A.3
-
127
-
-
0029024834
-
DNA synthesis errors associated with double-strand-break repair
-
Strathern JN, Shafer BK, McGill CB. 1995. DNA synthesis errors associated with double-strand-break repair. Genetics 140:965-72
-
(1995)
Genetics
, vol.140
, pp. 965-972
-
-
Strathern, J.N.1
Shafer, B.K.2
McGill, C.B.3
-
128
-
-
84908345680
-
MMS exposure promotes increased MtDNA mutagenesis in the presence of replication-defective disease-associated DNA polymerase γvariants
-
Stumpf JD, CopelandWC. 2014. MMS exposure promotes increased MtDNA mutagenesis in the presence of replication-defective disease-associated DNA polymerase γvariants. PLOS Genet. 10:e1004748
-
(2014)
PLOS Genet
, vol.10
, pp. e1004748
-
-
Stumpf, J.D.1
Copeland, W.C.2
-
129
-
-
84895917491
-
Molecular evolution of vertebrate neurotrophins: Co-option of the highly conserved nerve growth factor gene into the advanced snake venom arsenal
-
Sunagar K, Fry BG, Jackson TN, Casewell NR, Undheim EA, et al. 2013. Molecular evolution of vertebrate neurotrophins: co-option of the highly conserved nerve growth factor gene into the advanced snake venom arsenal. PLOS ONE 8:e81827
-
(2013)
PLOS ONE
, vol.8
, pp. e81827
-
-
Sunagar, K.1
Fry, B.G.2
Jackson, T.N.3
Casewell, N.R.4
Undheim, E.A.5
-
131
-
-
84879061509
-
DNA deaminases induce breakassociated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis
-
Taylor BJ, Nik-Zainal S, Wu YL, Stebbings LA, Raine K, et al. 2013. DNA deaminases induce breakassociated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis. eLife 2:e00534
-
(2013)
ELife
, vol.2
, pp. e00534
-
-
Taylor, B.J.1
Nik-Zainal, S.2
Wu, Y.L.3
Stebbings, L.A.4
Raine, K.5
-
132
-
-
84922298785
-
Active RNAP pre-initiation sites are highly mutated by cytidine deaminases in yeast, with AID targeting small RNA genes
-
Taylor BJ, Wu YL, Rada C. 2014. Active RNAP pre-initiation sites are highly mutated by cytidine deaminases in yeast, with AID targeting small RNA genes. eLife 3:e03553
-
(2014)
ELife
, vol.3
, pp. e03553
-
-
Taylor, B.J.1
Wu, Y.L.2
Rada, C.3
-
133
-
-
39049145798
-
Immunoglobulin somatic hypermutation
-
Teng G, Papavasiliou FN. 2007. Immunoglobulin somatic hypermutation. Annu. Rev. Genet. 41:107-20
-
(2007)
Annu. Rev. Genet
, vol.41
, pp. 107-120
-
-
Teng, G.1
Papavasiliou, F.N.2
-
135
-
-
34347214120
-
Evidence for mutation showers
-
Wang J, Gonzalez KD, Scaringe WA, Tsai K, Liu N, et al. 2007. Evidence for mutation showers. PNAS 104:8403-8
-
(2007)
PNAS
, vol.104
, pp. 8403-8408
-
-
Wang, J.1
Gonzalez, K.D.2
Scaringe, W.A.3
Tsai, K.4
Liu, N.5
-
136
-
-
21044435697
-
Perspective: Sign epistasis and genetic constraint on evolutionary trajectories
-
Weinreich DM,Watson RA, Chao L. 2005. Perspective: sign epistasis and genetic constraint on evolutionary trajectories. Evolution 59:1165-74
-
(2005)
Evolution
, vol.59
, pp. 1165-1174
-
-
Weinreich, D.M.1
Watson, R.A.2
Chao, L.3
-
137
-
-
84901321535
-
Structural insights into the evolution of a sexy protein: Novel topology and restricted backbone flexibility in a hypervariable pheromone from the red-legged salamander, Plethodon shermani
-
WilburnDB, Bowen KE, Doty KA, Arumugam S, Lane AN, et al. 2014. Structural insights into the evolution of a sexy protein: novel topology and restricted backbone flexibility in a hypervariable pheromone from the red-legged salamander, Plethodon shermani. PLOS ONE 9:e96975
-
(2014)
PLOS ONE
, vol.9
, pp. e96975
-
-
Wilburn, D.B.1
Bowen, K.E.2
Doty, K.A.3
Arumugam, S.4
Lane, A.N.5
-
138
-
-
84903542170
-
BRCA1 controls homologous recombination at Tus/Ter-stalled mammalian replication forks
-
Willis NA, Chandramouly G, Huang B, Kwok A, Follonier C, et al. 2014. BRCA1 controls homologous recombination at Tus/Ter-stalled mammalian replication forks. Nature 510:556-59
-
(2014)
Nature
, vol.510
, pp. 556-559
-
-
Willis, N.A.1
Chandramouly, G.2
Huang, B.3
Kwok, A.4
Follonier, C.5
-
139
-
-
0000907353
-
The roles of mutation, inbreeding, crossbreading and selection in evolution
-
Wright S. 1932. The roles of mutation, inbreeding, crossbreading and selection in evolution. Proc. Sixth Int. Congr. Genet. 1:356-66
-
(1932)
Proc. Sixth Int. Congr. Genet
, vol.1
, pp. 356-366
-
-
Wright, S.1
-
140
-
-
84885093727
-
APOBEC3 deletion polymorphism is associated with breast cancer risk among women of European ancestry
-
Xuan D, Li G, Cai Q, Deming-Halverson S, Shrubsole MJ, et al. 2013. APOBEC3 deletion polymorphism is associated with breast cancer risk among women of European ancestry. Carcinogenesis 34:2240-43
-
(2013)
Carcinogenesis
, vol.34
, pp. 2240-2243
-
-
Xuan, D.1
Li, G.2
Cai, Q.3
Deming-Halverson, S.4
Shrubsole, M.J.5
-
141
-
-
34249671724
-
Virion-associated uracil DNA glycosylase-2 and apurinic/apyrimidinic endonuclease are involved in the degradation of APOBEC3G-edited nascent HIV-1 DNA
-
Yang B, Chen K, Zhang C, Huang S, Zhang H. 2007. Virion-associated uracil DNA glycosylase-2 and apurinic/apyrimidinic endonuclease are involved in the degradation of APOBEC3G-edited nascent HIV-1 DNA. J. Biol. Chem. 282:11667-75
-
(2007)
J. Biol. Chem
, vol.282
, pp. 11667-11675
-
-
Yang, B.1
Chen, K.2
Zhang, C.3
Huang, S.4
Zhang, H.5
-
142
-
-
77955274581
-
A single-strand specific lesion drives MMS-induced hypermutability at a double-strand break in yeast
-
Yang Y, Gordenin DA, Resnick MA. 2010. A single-strand specific lesion drives MMS-induced hypermutability at a double-strand break in yeast. DNA Repair (Amst.) 9:914-21
-
(2010)
DNA Repair (Amst. )
, vol.9
, pp. 914-921
-
-
Yang, Y.1
Gordenin, D.A.2
Resnick, M.A.3
-
143
-
-
57149094856
-
Hypermutability of damaged singlestrand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae
-
Yang Y, Sterling J, Storici F, Resnick MA, Gordenin DA. 2008. Hypermutability of damaged singlestrand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae. PLOS Genet. 4:e1000264
-
(2008)
PLOS Genet
, vol.4
, pp. e1000264
-
-
Yang, Y.1
Sterling, J.2
Storici, F.3
Resnick, M.A.4
Gordenin, D.A.5
|