Oxidative stress-induced mutagenesis in single-strand DNA occurs primarily at cytosines and is DNA polymerase zeta-dependent only for adenines and guanines

Nucleic Acids Research

Volumn 41, Issue 19, 2013, Pages 8995-9005

  Degtyareva, Natalya P ^a,b   Heyburn, Lanier ^a   Sterling, Joan ^c   Resnick, Michael A ^c   Gordenin, Dmitry A ^c   Doetsch, Paul W ^a,b  

^a Department of Biochemistry ^*  (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CYTOSINE; DNA DIRECTED DNA POLYMERASE; DNA DIRECTED DNA POLYMERASE ZETA; GUANINE; MESYLIC ACID METHYL ESTER; REACTIVE OXYGEN METABOLITE; SINGLE STRANDED DNA; SULFITE; UNCLASSIFIED DRUG;

ALKYLATION; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DEAMINATION; DNA DAMAGE; DNA SYNTHESIS; MUTAGENESIS; MUTATION; OXIDATIVE STRESS; PRIORITY JOURNAL; TRANSLESION SYNTHESIS; ULTRAVIOLET IRRADIATION; YEAST;

ADENINE; CYTOSINE; DNA; DNA, SINGLE-STRANDED; DNA-DIRECTED DNA POLYMERASE; GUANINE; HYDROGEN PEROXIDE; MUTAGENESIS; OXIDATIVE STRESS; PARAQUAT; REACTIVE OXYGEN SPECIES; SACCHAROMYCETALES;

EID: 84886073963     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt671     Document Type: Article

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