-
1
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
Australian Pancreatic Cancer Genome Initiative, ICGC Breast Cancer ConsortiumICGC Breast Cancer Consortium, ICGC MMML-Seq ConsortiumICGC MMML-Seq Consortium, ICGC PedBrainICGC PedBrain
-
Alexandrov L.B., Nik-Zainal S., Wedge D.C., Aparicio S.A., Behjati S., Biankin A.V., Bignell G.R., Bolli N., Borg A., Børresen-Dale A.L., et al. Signatures of mutational processes in human cancer. Nature 2013, 500:415-421. Australian Pancreatic Cancer Genome Initiative, ICGC Breast Cancer ConsortiumICGC Breast Cancer Consortium, ICGC MMML-Seq ConsortiumICGC MMML-Seq Consortium, ICGC PedBrainICGC PedBrain.
-
(2013)
Nature
, vol.500
, pp. 415-421
-
-
Alexandrov, L.B.1
Nik-Zainal, S.2
Wedge, D.C.3
Aparicio, S.A.4
Behjati, S.5
Biankin, A.V.6
Bignell, G.R.7
Bolli, N.8
Borg, A.9
Børresen-Dale, A.L.10
-
2
-
-
84874188583
-
APOBEC3B is an enzymatic source of mutation in breast cancer
-
Burns M.B., Lackey L., Carpenter M.A., Rathore A., Land A.M., Leonard B., Refsland E.W., Kotandeniya D., Tretyakova N., Nikas J.B., et al. APOBEC3B is an enzymatic source of mutation in breast cancer. Nature 2013, 494:366-370.
-
(2013)
Nature
, vol.494
, pp. 366-370
-
-
Burns, M.B.1
Lackey, L.2
Carpenter, M.A.3
Rathore, A.4
Land, A.M.5
Leonard, B.6
Refsland, E.W.7
Kotandeniya, D.8
Tretyakova, N.9
Nikas, J.B.10
-
3
-
-
35148875679
-
Genetic constraints on protein evolution
-
Camps M., Herman A., Loh E., Loeb L.A. Genetic constraints on protein evolution. Crit. Rev. Biochem. Mol. Biol. 2007, 42:313-326.
-
(2007)
Crit. Rev. Biochem. Mol. Biol.
, vol.42
, pp. 313-326
-
-
Camps, M.1
Herman, A.2
Loh, E.3
Loeb, L.A.4
-
4
-
-
84872008477
-
Base damage within single-strand DNA underlies invivo hypermutability induced by a ubiquitous environmental agent
-
Chan K., Sterling J.F., Roberts S.A., Bhagwat A.S., Resnick M.A., Gordenin D.A. Base damage within single-strand DNA underlies invivo hypermutability induced by a ubiquitous environmental agent. PLoS Genet. 2012, 8:e1003149.
-
(2012)
PLoS Genet.
, vol.8
-
-
Chan, K.1
Sterling, J.F.2
Roberts, S.A.3
Bhagwat, A.S.4
Resnick, M.A.5
Gordenin, D.A.6
-
5
-
-
77953224210
-
Defective resection at DNA double-strand breaks leads to de novo telomere formation and enhances gene targeting
-
Chung W.H., Zhu Z., Papusha A., Malkova A., Ira G. Defective resection at DNA double-strand breaks leads to de novo telomere formation and enhances gene targeting. PLoS Genet. 2010, 6:e1000948.
-
(2010)
PLoS Genet.
, vol.6
-
-
Chung, W.H.1
Zhu, Z.2
Papusha, A.3
Malkova, A.4
Ira, G.5
-
6
-
-
84892743776
-
Break-induced replication repair of damaged forks induces genomic duplications in human cells
-
Costantino L., Sotiriou S.K., Rantala J.K., Magin S., Mladenov E., Helleday T., Haber J.E., Iliakis G., Kallioniemi O.P., Halazonetis T.D. Break-induced replication repair of damaged forks induces genomic duplications in human cells. Science 2014, 343:88-91.
-
(2014)
Science
, vol.343
, pp. 88-91
-
-
Costantino, L.1
Sotiriou, S.K.2
Rantala, J.K.3
Magin, S.4
Mladenov, E.5
Helleday, T.6
Haber, J.E.7
Iliakis, G.8
Kallioniemi, O.P.9
Halazonetis, T.D.10
-
7
-
-
53349168503
-
Defective break-induced replication leads to half-crossovers in Saccharomyces cerevisiae
-
Deem A., Barker K., Vanhulle K., Downing B., Vayl A., Malkova A. Defective break-induced replication leads to half-crossovers in Saccharomyces cerevisiae. Genetics 2008, 179:1845-1860.
-
(2008)
Genetics
, vol.179
, pp. 1845-1860
-
-
Deem, A.1
Barker, K.2
Vanhulle, K.3
Downing, B.4
Vayl, A.5
Malkova, A.6
-
8
-
-
4644282150
-
Mutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coli
-
Delaney J.C., Essigmann J.M. Mutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coli. Proc. Natl. Acad. Sci. USA 2004, 101:14051-14056.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 14051-14056
-
-
Delaney, J.C.1
Essigmann, J.M.2
-
9
-
-
84882372684
-
Break-induced replication occurs by conservative DNA synthesis
-
Donnianni R.A., Symington L.S. Break-induced replication occurs by conservative DNA synthesis. Proc. Natl. Acad. Sci. USA 2013, 110:13475-13480.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 13475-13480
-
-
Donnianni, R.A.1
Symington, L.S.2
-
10
-
-
84873390533
-
Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability
-
Drier Y., Lawrence M.S., Carter S.L., Stewart C., Gabriel S.B., Lander E.S., Meyerson M., Beroukhim R., Getz G. Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability. Genome Res. 2013, 23:228-235.
-
(2013)
Genome Res.
, vol.23
, pp. 228-235
-
-
Drier, Y.1
Lawrence, M.S.2
Carter, S.L.3
Stewart, C.4
Gabriel, S.B.5
Lander, E.S.6
Meyerson, M.7
Beroukhim, R.8
Getz, G.9
-
12
-
-
40449120350
-
An oncogene-induced DNA damage model for cancer development
-
Halazonetis T.D., Gorgoulis V.G., Bartek J. An oncogene-induced DNA damage model for cancer development. Science 2008, 319:1352-1355.
-
(2008)
Science
, vol.319
, pp. 1352-1355
-
-
Halazonetis, T.D.1
Gorgoulis, V.G.2
Bartek, J.3
-
13
-
-
84871174239
-
AID/APOBEC cytosine deaminase induces genome-wide kataegis
-
discussion 47
-
Lada A.G., Dhar A., Boissy R.J., Hirano M., Rubel A.A., Rogozin I.B., Pavlov Y.I. AID/APOBEC cytosine deaminase induces genome-wide kataegis. Biol. Direct 2012, 7:47. discussion 47.
-
(2012)
Biol. Direct
, vol.7
, pp. 47
-
-
Lada, A.G.1
Dhar, A.2
Boissy, R.J.3
Hirano, M.4
Rubel, A.A.5
Rogozin, I.B.6
Pavlov, Y.I.7
-
14
-
-
84884686754
-
Genome-wide mutation avalanches induced in diploid yeast cells by a base analog or an APOBEC deaminase
-
Lada A.G., Stepchenkova E.I., Waisertreiger I.S., Noskov V.N., Dhar A., Eudy J.D., Boissy R.J., Hirano M., Rogozin I.B., Pavlov Y.I. Genome-wide mutation avalanches induced in diploid yeast cells by a base analog or an APOBEC deaminase. PLoS Genet. 2013, 9:e1003736.
-
(2013)
PLoS Genet.
, vol.9
-
-
Lada, A.G.1
Stepchenkova, E.I.2
Waisertreiger, I.S.3
Noskov, V.N.4
Dhar, A.5
Eudy, J.D.6
Boissy, R.J.7
Hirano, M.8
Rogozin, I.B.9
Pavlov, Y.I.10
-
15
-
-
84879887310
-
Break-induced replication: functions and molecular mechanism
-
Malkova A., Ira G. Break-induced replication: functions and molecular mechanism. Curr. Opin. Genet. Dev. 2013, 23:271-279.
-
(2013)
Curr. Opin. Genet. Dev.
, vol.23
, pp. 271-279
-
-
Malkova, A.1
Ira, G.2
-
16
-
-
12844289007
-
RAD51-dependent break-induced replication differs in kinetics and checkpoint responses from RAD51-mediated gene conversion
-
Malkova A., Naylor M.L., Yamaguchi M., Ira G., Haber J.E. RAD51-dependent break-induced replication differs in kinetics and checkpoint responses from RAD51-mediated gene conversion. Mol. Cell. Biol. 2005, 25:933-944.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 933-944
-
-
Malkova, A.1
Naylor, M.L.2
Yamaguchi, M.3
Ira, G.4
Haber, J.E.5
-
17
-
-
84861541343
-
Mutational processes molding the genomes of 21 breast cancers
-
Breast Cancer Working Group of the International Cancer Genome Consortium
-
Nik-Zainal S., Alexandrov L.B., Wedge D.C., Van Loo P., Greenman C.D., Raine K., Jones D., Hinton J., Marshall J., Stebbings L.A., et al. Mutational processes molding the genomes of 21 breast cancers. Cell 2012, 149:979-993. Breast Cancer Working Group of the International Cancer Genome Consortium.
-
(2012)
Cell
, vol.149
, pp. 979-993
-
-
Nik-Zainal, S.1
Alexandrov, L.B.2
Wedge, D.C.3
Van Loo, P.4
Greenman, C.D.5
Raine, K.6
Jones, D.7
Hinton, J.8
Marshall, J.9
Stebbings, L.A.10
-
18
-
-
84870377034
-
A single-nucleotide substitution mutator phenotype revealed by exome sequencing of human colon adenomas
-
Nikolaev S.I., Sotiriou S.K., Pateras I.S., Santoni F., Sougioultzis S., Edgren H., Almusa H., Robyr D., Guipponi M., Saarela J., et al. A single-nucleotide substitution mutator phenotype revealed by exome sequencing of human colon adenomas. Cancer Res. 2012, 72:6279-6289.
-
(2012)
Cancer Res.
, vol.72
, pp. 6279-6289
-
-
Nikolaev, S.I.1
Sotiriou, S.K.2
Pateras, I.S.3
Santoni, F.4
Sougioultzis, S.5
Edgren, H.6
Almusa, H.7
Robyr, D.8
Guipponi, M.9
Saarela, J.10
-
19
-
-
84861460657
-
Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions
-
Roberts S.A., Sterling J., Thompson C., Harris S., Mav D., Shah R., Klimczak L.J., Kryukov G.V., Malc E., Mieczkowski P.A., et al. Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions. Mol. Cell 2012, 46:424-435.
-
(2012)
Mol. Cell
, vol.46
, pp. 424-435
-
-
Roberts, S.A.1
Sterling, J.2
Thompson, C.3
Harris, S.4
Mav, D.5
Shah, R.6
Klimczak, L.J.7
Kryukov, G.V.8
Malc, E.9
Mieczkowski, P.A.10
-
20
-
-
84883432724
-
An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers
-
Roberts S.A., Lawrence M.S., Klimczak L.J., Grimm S.A., Fargo D., Stojanov P., Kiezun A., Kryukov G.V., Carter S.L., Saksena G., et al. An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers. Nat. Genet. 2013, 45:970-976.
-
(2013)
Nat. Genet.
, vol.45
, pp. 970-976
-
-
Roberts, S.A.1
Lawrence, M.S.2
Klimczak, L.J.3
Grimm, S.A.4
Fargo, D.5
Stojanov, P.6
Kiezun, A.7
Kryukov, G.V.8
Carter, S.L.9
Saksena, G.10
-
21
-
-
84885843906
-
Migrating bubble during break-induced replication drives conservative DNA synthesis
-
Saini N., Ramakrishnan S., Elango R., Ayyar S., Zhang Y., Deem A., Ira G., Haber J.E., Lobachev K.S., Malkova A. Migrating bubble during break-induced replication drives conservative DNA synthesis. Nature 2013, 502:389-392.
-
(2013)
Nature
, vol.502
, pp. 389-392
-
-
Saini, N.1
Ramakrishnan, S.2
Elango, R.3
Ayyar, S.4
Zhang, Y.5
Deem, A.6
Ira, G.7
Haber, J.E.8
Lobachev, K.S.9
Malkova, A.10
-
22
-
-
62849117547
-
Aberrant double-strand break repair resulting in half crossovers in mutants defective for Rad51 or the DNA polymerase delta complex
-
Smith C.E., Lam A.F., Symington L.S. Aberrant double-strand break repair resulting in half crossovers in mutants defective for Rad51 or the DNA polymerase delta complex. Mol. Cell. Biol. 2009, 29:1432-1441.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 1432-1441
-
-
Smith, C.E.1
Lam, A.F.2
Symington, L.S.3
-
23
-
-
84879061509
-
DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis
-
Taylor B.J., Nik-Zainal S., Wu Y.L., Stebbings L.A., Raine K., Campbell P.J., Rada C., Stratton M.R., Neuberger M.S. DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis. Elife 2013, 2:e00534.
-
(2013)
Elife
, vol.2
-
-
Taylor, B.J.1
Nik-Zainal, S.2
Wu, Y.L.3
Stebbings, L.A.4
Raine, K.5
Campbell, P.J.6
Rada, C.7
Stratton, M.R.8
Neuberger, M.S.9
-
24
-
-
84901740999
-
Cascades of genetic instability resulting from compromised break-induced replication
-
Vasan S., Deem A., Ramakrishnan S., Argueso J.L., Malkova A. Cascades of genetic instability resulting from compromised break-induced replication. PLoS Genet. 2014, 10:e1004119.
-
(2014)
PLoS Genet.
, vol.10
-
-
Vasan, S.1
Deem, A.2
Ramakrishnan, S.3
Argueso, J.L.4
Malkova, A.5
-
25
-
-
84885866032
-
Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration
-
Wilson M.A., Kwon Y., Xu Y., Chung W.H., Chi P., Niu H., Mayle R., Chen X., Malkova A., Sung P., Ira G. Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration. Nature 2013, 502:393-396.
-
(2013)
Nature
, vol.502
, pp. 393-396
-
-
Wilson, M.A.1
Kwon, Y.2
Xu, Y.3
Chung, W.H.4
Chi, P.5
Niu, H.6
Mayle, R.7
Chen, X.8
Malkova, A.9
Sung, P.10
Ira, G.11
-
26
-
-
57149094856
-
Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae
-
Yang Y., Sterling J., Storici F., Resnick M.A., Gordenin D.A. Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae. PLoS Genet. 2008, 4:e1000264.
-
(2008)
PLoS Genet.
, vol.4
-
-
Yang, Y.1
Sterling, J.2
Storici, F.3
Resnick, M.A.4
Gordenin, D.A.5
-
27
-
-
77955274581
-
A single-strand specific lesion drives MMS-induced hyper-mutability at a double-strand break in yeast
-
Yang Y., Gordenin D.A., Resnick M.A. A single-strand specific lesion drives MMS-induced hyper-mutability at a double-strand break in yeast. DNA Repair (Amst.) 2010, 9:914-921.
-
(2010)
DNA Repair (Amst.)
, vol.9
, pp. 914-921
-
-
Yang, Y.1
Gordenin, D.A.2
Resnick, M.A.3
|