-
1
-
-
0032519426
-
Increased apoptosis of T cell subsets in aging humans: altered expression of Fas (CD95), Fas ligand, Bcl-2, and Bax
-
Aggarwal S., Gupta S. Increased apoptosis of T cell subsets in aging humans: altered expression of Fas (CD95), Fas ligand, Bcl-2, and Bax. J. Immunol. 1998, 160:1627-1637.
-
(1998)
J. Immunol.
, vol.160
, pp. 1627-1637
-
-
Aggarwal, S.1
Gupta, S.2
-
2
-
-
0033558334
-
Increased TNF-alpha-induced apoptosis in lymphocytes from aged humans: changes in TNF-alpha receptor expression and activation of caspases
-
Aggarwal S., Gollapudi S., Gupta S. Increased TNF-alpha-induced apoptosis in lymphocytes from aged humans: changes in TNF-alpha receptor expression and activation of caspases. J. Immunol. 1999, 162:2154-2161.
-
(1999)
J. Immunol.
, vol.162
, pp. 2154-2161
-
-
Aggarwal, S.1
Gollapudi, S.2
Gupta, S.3
-
3
-
-
33746217907
-
How T lymphocytes switch between life and death
-
Arnold R., Brenner D., Becker M., Frey C.R., Krammer P.H. How T lymphocytes switch between life and death. Eur. J. Immunol. 2006, 36:1654-1658.
-
(2006)
Eur. J. Immunol.
, vol.36
, pp. 1654-1658
-
-
Arnold, R.1
Brenner, D.2
Becker, M.3
Frey, C.R.4
Krammer, P.H.5
-
4
-
-
84898879369
-
T cell receptor-mediated activation is a potent inducer of macroautophagy in human CD8(+)CD28(+) T cells but not in CD8(+)CD28(-) T cells
-
Arnold C.R., Pritz T., Brunner S., Knabb C., Salvenmoser W., Holzwarth B., Thedieck K., Grubeck-Loebenstein B. T cell receptor-mediated activation is a potent inducer of macroautophagy in human CD8(+)CD28(+) T cells but not in CD8(+)CD28(-) T cells. Exp. Gerontol. 2014, 54:75-83.
-
(2014)
Exp. Gerontol.
, vol.54
, pp. 75-83
-
-
Arnold, C.R.1
Pritz, T.2
Brunner, S.3
Knabb, C.4
Salvenmoser, W.5
Holzwarth, B.6
Thedieck, K.7
Grubeck-Loebenstein, B.8
-
5
-
-
80051518362
-
Age-dependent increases in apoptosis/necrosis ratios in human lymphocytes exposed to oxidative stress
-
Behrens M.I., Silva M., Schmied A., Salech F., Manzur H., Rebolledo R., Bull R., Torres V., Henriquez M., Quest A.F. Age-dependent increases in apoptosis/necrosis ratios in human lymphocytes exposed to oxidative stress. J. Gerontol. A Biol. Sci. Med. Sci. 2011, 66:732-740.
-
(2011)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.66
, pp. 732-740
-
-
Behrens, M.I.1
Silva, M.2
Schmied, A.3
Salech, F.4
Manzur, H.5
Rebolledo, R.6
Bull, R.7
Torres, V.8
Henriquez, M.9
Quest, A.F.10
-
6
-
-
84866120008
-
Inverse susceptibility to oxidative death of lymphocytes obtained from Alzheimer's patients and skin cancer survivors: increased apoptosis in Alzheimer's and reduced necrosis in cancer
-
Behrens M.I., Silva M., Salech F., Ponce D.P., Merino D., Sinning M., Xiong C., Roe C.M., Quest A.F. Inverse susceptibility to oxidative death of lymphocytes obtained from Alzheimer's patients and skin cancer survivors: increased apoptosis in Alzheimer's and reduced necrosis in cancer. J. Gerontol. A Biol. Sci. Med. Sci. 2012, 67:1036-1040.
-
(2012)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.67
, pp. 1036-1040
-
-
Behrens, M.I.1
Silva, M.2
Salech, F.3
Ponce, D.P.4
Merino, D.5
Sinning, M.6
Xiong, C.7
Roe, C.M.8
Quest, A.F.9
-
7
-
-
55949083821
-
FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells
-
Bell B.D., Leverrier S., Weist B.M., Newton R.H., Arechiga A.F., Luhrs K.A., Morrissette N.S., Walsh C.M. FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:16677-16682.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 16677-16682
-
-
Bell, B.D.1
Leverrier, S.2
Weist, B.M.3
Newton, R.H.4
Arechiga, A.F.5
Luhrs, K.A.6
Morrissette, N.S.7
Walsh, C.M.8
-
8
-
-
29244440885
-
Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death
-
Brenner D., Golks A., Kiefer F., Krammer P.H., Arnold R. Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death. EMBO J. 2005, 24:4279-4290.
-
(2005)
EMBO J.
, vol.24
, pp. 4279-4290
-
-
Brenner, D.1
Golks, A.2
Kiefer, F.3
Krammer, P.H.4
Arnold, R.5
-
9
-
-
84864018624
-
Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8(+) T cells sensitizing them to apoptotic cell death
-
Brunner S., Herndler-Brandstetter D., Arnold C.R., Wiegers G.J., Villunger A., Hackl M., Grillari J., Moreno-Villanueva M., Burkle A., Grubeck-Loebenstein B. Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8(+) T cells sensitizing them to apoptotic cell death. Aging Cell 2012.
-
(2012)
Aging Cell
-
-
Brunner, S.1
Herndler-Brandstetter, D.2
Arnold, C.R.3
Wiegers, G.J.4
Villunger, A.5
Hackl, M.6
Grillari, J.7
Moreno-Villanueva, M.8
Burkle, A.9
Grubeck-Loebenstein, B.10
-
10
-
-
0037396242
-
Proliferation of CD8+ in culture of human T cells derived from peripheral blood of adult donors and cord blood of newborns
-
Brzezinska A., Magalska A., Sikora E. Proliferation of CD8+ in culture of human T cells derived from peripheral blood of adult donors and cord blood of newborns. Mech. Ageing Dev. 2003, 124:379-387.
-
(2003)
Mech. Ageing Dev.
, vol.124
, pp. 379-387
-
-
Brzezinska, A.1
Magalska, A.2
Sikora, E.3
-
11
-
-
18744422561
-
Proliferation and apoptosis of human CD8(+)CD28(+) and CD8(+)CD28(-) lymphocytes during aging
-
Brzezinska A., Magalska A., Szybinska A., Sikora E. Proliferation and apoptosis of human CD8(+)CD28(+) and CD8(+)CD28(-) lymphocytes during aging. Exp. Gerontol. 2004, 39:539-544.
-
(2004)
Exp. Gerontol.
, vol.39
, pp. 539-544
-
-
Brzezinska, A.1
Magalska, A.2
Szybinska, A.3
Sikora, E.4
-
12
-
-
31544482406
-
Does in vitro replicative senescence of human CD8+ cells reflect the phenotypic changes observed during in vivo ageing?
-
Brzezinska A. Does in vitro replicative senescence of human CD8+ cells reflect the phenotypic changes observed during in vivo ageing?. Acta Biochim. Pol. 2005, 52:931-935.
-
(2005)
Acta Biochim. Pol.
, vol.52
, pp. 931-935
-
-
Brzezinska, A.1
-
13
-
-
0038049143
-
Cancer and ageing: rival demons?
-
Campisi J. Cancer and ageing: rival demons?. Nat. Rev. Cancer 2003, 3:339-349.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 339-349
-
-
Campisi, J.1
-
14
-
-
33749457668
-
Complexity of anti-immunosenescence strategies in humans
-
Capri M., Monti D., Salvioli S., Lescai F., Pierini M., Altilia S., Sevini F., Valensin S., Ostan R., Bucci L., Franceschi C. Complexity of anti-immunosenescence strategies in humans. Artif. Organs 2006, 30:730-742.
-
(2006)
Artif. Organs
, vol.30
, pp. 730-742
-
-
Capri, M.1
Monti, D.2
Salvioli, S.3
Lescai, F.4
Pierini, M.5
Altilia, S.6
Sevini, F.7
Valensin, S.8
Ostan, R.9
Bucci, L.10
Franceschi, C.11
-
15
-
-
56249132503
-
Antigen-mediated T cell expansion regulated by parallel pathways of death
-
Ch'en I.L., Beisner D.R., Degterev A., Lynch C., Yuan J., Hoffmann A., Hedrick S.M. Antigen-mediated T cell expansion regulated by parallel pathways of death. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:17463-17468.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 17463-17468
-
-
Ch'en, I.L.1
Beisner, D.R.2
Degterev, A.3
Lynch, C.4
Yuan, J.5
Hoffmann, A.6
Hedrick, S.M.7
-
16
-
-
67649393351
-
Vaccination in the elderly: an immunological perspective
-
Chen W.H., Kozlovsky B.F., Effros R.B., Grubeck-Loebenstein B., Edelman R., Sztein M.B. Vaccination in the elderly: an immunological perspective. Trends Immunol. 2009, 30:351-359.
-
(2009)
Trends Immunol.
, vol.30
, pp. 351-359
-
-
Chen, W.H.1
Kozlovsky, B.F.2
Effros, R.B.3
Grubeck-Loebenstein, B.4
Edelman, R.5
Sztein, M.B.6
-
17
-
-
33646756222
-
Dissecting p53-dependent apoptosis
-
Chipuk J.E., Green D.R. Dissecting p53-dependent apoptosis. Cell Death Differ. 2006, 13:994-1002.
-
(2006)
Cell Death Differ.
, vol.13
, pp. 994-1002
-
-
Chipuk, J.E.1
Green, D.R.2
-
18
-
-
77951251430
-
Necroptosis as an alternative form of programmed cell death
-
Christofferson D.E., Yuan J. Necroptosis as an alternative form of programmed cell death. Curr. Opin. Cell Biol. 2010, 22:263-268.
-
(2010)
Curr. Opin. Cell Biol.
, vol.22
, pp. 263-268
-
-
Christofferson, D.E.1
Yuan, J.2
-
19
-
-
34250163578
-
Apoptosis remodeling in immunosenescence: implications for strategies to delay ageing
-
De Martinis, Franceschi C., Monti D., Ginaldi L. Apoptosis remodeling in immunosenescence: implications for strategies to delay ageing. Curr. Med. Chem. 2007, 14:1389-1397.
-
(2007)
Curr. Med. Chem.
, vol.14
, pp. 1389-1397
-
-
De, Martinis1
Franceschi, C.2
Monti, D.3
Ginaldi, L.4
-
20
-
-
73649125846
-
Altered T-cell subtypes in spondyloarthritis, rheumatoid arthritis and polymyalgia rheumatica
-
Dejaco C., Duftner C., Klauser A., Schirmer M. Altered T-cell subtypes in spondyloarthritis, rheumatoid arthritis and polymyalgia rheumatica. Rheumatol. Int. 2010, 30:297-303.
-
(2010)
Rheumatol. Int.
, vol.30
, pp. 297-303
-
-
Dejaco, C.1
Duftner, C.2
Klauser, A.3
Schirmer, M.4
-
21
-
-
0037012044
-
Age associated decline in CD25 and CD28 expression correlate with an increased susceptibility to CD95 mediated apoptosis in T cells
-
Dennett N.S., Barcia R.N., McLeod J.D. Age associated decline in CD25 and CD28 expression correlate with an increased susceptibility to CD95 mediated apoptosis in T cells. Exp. Gerontol. 2002, 37:271-283.
-
(2002)
Exp. Gerontol.
, vol.37
, pp. 271-283
-
-
Dennett, N.S.1
Barcia, R.N.2
McLeod, J.D.3
-
22
-
-
23644438163
-
Age-related susceptibility of naive and memory CD4T cells to apoptosis induced by IL-2 deprivation or PHA addition
-
Donnini A., Re F., Bollettini M., Moresi R., Tesei S., Bernardini G., Provinciali M. Age-related susceptibility of naive and memory CD4T cells to apoptosis induced by IL-2 deprivation or PHA addition. Biogerontology 2005, 6:193-204.
-
(2005)
Biogerontology
, vol.6
, pp. 193-204
-
-
Donnini, A.1
Re, F.2
Bollettini, M.3
Moresi, R.4
Tesei, S.5
Bernardini, G.6
Provinciali, M.7
-
23
-
-
57749208337
-
CD4+ CD28 null T cells in coronary artery disease: when helpers become killers
-
Dumitriu I.E., Araguas E.T., Baboonian C., Kaski J.C. CD4+ CD28 null T cells in coronary artery disease: when helpers become killers. Cardiovasc. Res. 2009, 81:11-19.
-
(2009)
Cardiovasc. Res.
, vol.81
, pp. 11-19
-
-
Dumitriu, I.E.1
Araguas, E.T.2
Baboonian, C.3
Kaski, J.C.4
-
24
-
-
20344373118
-
The role of CD8+ T-cell replicative senescence in human aging
-
Effros R.B., Dagarag M., Spaulding C., Man J. The role of CD8+ T-cell replicative senescence in human aging. Immunol. Rev. 2005, 205:147-157.
-
(2005)
Immunol. Rev.
, vol.205
, pp. 147-157
-
-
Effros, R.B.1
Dagarag, M.2
Spaulding, C.3
Man, J.4
-
25
-
-
0034194058
-
Shortage of circulating naive CD8(+) T cells provides new insights on immunodeficiency in aging
-
Fagnoni F.F., Vescovini R., Passeri G., Bologna G., Pedrazzoni M., Lavagetto G., Casti A., Franceschi C., Passeri M., Sansoni P. Shortage of circulating naive CD8(+) T cells provides new insights on immunodeficiency in aging. Blood 2000, 95:2860-2868.
-
(2000)
Blood
, vol.95
, pp. 2860-2868
-
-
Fagnoni, F.F.1
Vescovini, R.2
Passeri, G.3
Bologna, G.4
Pedrazzoni, M.5
Lavagetto, G.6
Casti, A.7
Franceschi, C.8
Passeri, M.9
Sansoni, P.10
-
26
-
-
0033911488
-
Inflamm-aging: An evolutionary perspective on immunosenescence
-
Franceschi C., Bonafe M., Valensin S., Olivieri F., De Luca M., Ottaviani E., De Benedictis G. Inflamm-aging: An evolutionary perspective on immunosenescence. Ann. N. Y. Acad. Sci. 2000, 908:244-254.
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.908
, pp. 244-254
-
-
Franceschi, C.1
Bonafe, M.2
Valensin, S.3
Olivieri, F.4
De Luca, M.5
Ottaviani, E.6
De Benedictis, G.7
-
27
-
-
77952105389
-
Inflammatory networks during cellular senescence: causes and consequences
-
Freund A., Orjalo A.V., Desprez P.Y., Campisi J. Inflammatory networks during cellular senescence: causes and consequences. Trends Mol. Med. 2010, 16:238-246.
-
(2010)
Trends Mol. Med.
, vol.16
, pp. 238-246
-
-
Freund, A.1
Orjalo, A.V.2
Desprez, P.Y.3
Campisi, J.4
-
28
-
-
3242891953
-
The immune system in the elderly: activation-induced and damage-induced apoptosis
-
Ginaldi L., De Martinis M., Monti D., Franceschi C. The immune system in the elderly: activation-induced and damage-induced apoptosis. Immunol. Res. 2004, 30:81-94.
-
(2004)
Immunol. Res.
, vol.30
, pp. 81-94
-
-
Ginaldi, L.1
De Martinis, M.2
Monti, D.3
Franceschi, C.4
-
29
-
-
12744253311
-
Chronic antigenic load and apoptosis in immunosenescence
-
Ginaldi L., De Martinis M., Monti D., Franceschi C. Chronic antigenic load and apoptosis in immunosenescence. Trends Immunol. 2005, 26:79-84.
-
(2005)
Trends Immunol.
, vol.26
, pp. 79-84
-
-
Ginaldi, L.1
De Martinis, M.2
Monti, D.3
Franceschi, C.4
-
30
-
-
39749133647
-
Apoptosis in the homeostasis of the immune system and in human immune mediated diseases
-
Giovannetti A., Pierdominici M., Di Iorio A., Cianci R., Murdaca G., Puppo F., Pandolfi F., Paganelli R. Apoptosis in the homeostasis of the immune system and in human immune mediated diseases. Curr. Pharm. Des. 2008, 14:253-268.
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 253-268
-
-
Giovannetti, A.1
Pierdominici, M.2
Di Iorio, A.3
Cianci, R.4
Murdaca, G.5
Puppo, F.6
Pandolfi, F.7
Paganelli, R.8
-
32
-
-
0033834612
-
The illusion of cell immortality
-
Hayflick L. The illusion of cell immortality. Br. J. Cancer 2000, 83:841-846.
-
(2000)
Br. J. Cancer
, vol.83
, pp. 841-846
-
-
Hayflick, L.1
-
33
-
-
0031011169
-
Increased apoptosis of CD45RO- T cells with aging
-
Herndon F.J., Hsu H.C., Mountz J.D. Increased apoptosis of CD45RO- T cells with aging. Mech. Ageing Dev. 1997, 94:123-134.
-
(1997)
Mech. Ageing Dev.
, vol.94
, pp. 123-134
-
-
Herndon, F.J.1
Hsu, H.C.2
Mountz, J.D.3
-
34
-
-
84881430701
-
Transmitting senescence to the cell neighbourhood
-
Hoare M., Narita M. Transmitting senescence to the cell neighbourhood. Nat. Cell Biol. 2013, 15:887-889.
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 887-889
-
-
Hoare, M.1
Narita, M.2
-
35
-
-
20344399856
-
Impaired apoptosis and immune senescence - cause or effect?
-
Hsu H.C., Scott D.K., Mountz J.D. Impaired apoptosis and immune senescence - cause or effect?. Immunol. Rev. 2005, 205:130-146.
-
(2005)
Immunol. Rev.
, vol.205
, pp. 130-146
-
-
Hsu, H.C.1
Scott, D.K.2
Mountz, J.D.3
-
36
-
-
45449084795
-
Cellular senescence and organismal aging
-
Jeyapalan J.C., Sedivy J.M. Cellular senescence and organismal aging. Mech. Ageing Dev. 2008, 129:467-474.
-
(2008)
Mech. Ageing Dev.
, vol.129
, pp. 467-474
-
-
Jeyapalan, J.C.1
Sedivy, J.M.2
-
37
-
-
0034802113
-
Functional decline in aging and disease: a role for apoptosis
-
Joaquin A.M., Gollapudi S. Functional decline in aging and disease: a role for apoptosis. J. Am. Geriatrics Soc. 2001, 49:1234-1240.
-
(2001)
J. Am. Geriatrics Soc.
, vol.49
, pp. 1234-1240
-
-
Joaquin, A.M.1
Gollapudi, S.2
-
38
-
-
0033790128
-
Up-regulation of c-FLIPshort and reduction of activation-induced cell death in CD28-costimulated human T cells
-
Kirchhoff S., Muller W.W., Li-Weber M., Krammer P.H. Up-regulation of c-FLIPshort and reduction of activation-induced cell death in CD28-costimulated human T cells. Eur. J. Immunol. 2000, 30:2765-2774.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 2765-2774
-
-
Kirchhoff, S.1
Muller, W.W.2
Li-Weber, M.3
Krammer, P.H.4
-
39
-
-
38949145803
-
A systematic look at an old problem
-
Kirkwood T.B. A systematic look at an old problem. Nature 2008, 451:644-647.
-
(2008)
Nature
, vol.451
, pp. 644-647
-
-
Kirkwood, T.B.1
-
41
-
-
0037833695
-
The role of CD95 in the regulation of peripheral T-cell apoptosis
-
Krueger A., Fas S.C., Baumann S., Krammer P.H. The role of CD95 in the regulation of peripheral T-cell apoptosis. Immunol. Rev. 2003, 193:58-69.
-
(2003)
Immunol. Rev.
, vol.193
, pp. 58-69
-
-
Krueger, A.1
Fas, S.C.2
Baumann, S.3
Krammer, P.H.4
-
42
-
-
78349257844
-
The essence of senescence
-
Kuilman T., Michaloglou C., Mooi W.J., Peeper D.S. The essence of senescence. Genes Dev. 2010, 24:2463-2479.
-
(2010)
Genes Dev.
, vol.24
, pp. 2463-2479
-
-
Kuilman, T.1
Michaloglou, C.2
Mooi, W.J.3
Peeper, D.S.4
-
43
-
-
0029977502
-
Regulation of CD95 (APO-1) expression and the induction of apoptosis in human T cells: changes in old age
-
Lechner H., Amort M., Steger M.M., Maczek C., Grubeck-Loebenstein B. Regulation of CD95 (APO-1) expression and the induction of apoptosis in human T cells: changes in old age. Int. Arch. Allergy Immunol. 1996, 110:238-243.
-
(1996)
Int. Arch. Allergy Immunol.
, vol.110
, pp. 238-243
-
-
Lechner, H.1
Amort, M.2
Steger, M.M.3
Maczek, C.4
Grubeck-Loebenstein, B.5
-
44
-
-
84877812916
-
Frailty, inflammation, and immunity
-
Li H., Manwani B., Leng S.X. Frailty, inflammation, and immunity. Aging Dis. 2011, 2:466-473.
-
(2011)
Aging Dis.
, vol.2
, pp. 466-473
-
-
Li, H.1
Manwani, B.2
Leng, S.X.3
-
45
-
-
0035409448
-
Programmed cell death and apoptosis: origins of the theory
-
Lockshin R.A., Zakeri Z. Programmed cell death and apoptosis: origins of the theory. Nat. Rev. Mol. Cell Biol. 2001, 2:545-550.
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 545-550
-
-
Lockshin, R.A.1
Zakeri, Z.2
-
46
-
-
37349039029
-
T-cell death and cancer immune tolerance
-
Lu B., Finn O.J. T-cell death and cancer immune tolerance. Cell Death Differ. 2008, 15:70-79.
-
(2008)
Cell Death Differ.
, vol.15
, pp. 70-79
-
-
Lu, B.1
Finn, O.J.2
-
47
-
-
84865296205
-
Programmed necrosis and autophagy in immune function
-
Lu J.V., Walsh C.M. Programmed necrosis and autophagy in immune function. Immunol. Rev. 2012, 249:205-217.
-
(2012)
Immunol. Rev.
, vol.249
, pp. 205-217
-
-
Lu, J.V.1
Walsh, C.M.2
-
48
-
-
84880956842
-
Virological and immunological characteristics of human cytomegalovirus infection associated with Alzheimer disease
-
Lurain N.S., Hanson B.A., Martinson J., Leurgans S.E., Landay A.L., Bennett D.A., Schneider J.A. Virological and immunological characteristics of human cytomegalovirus infection associated with Alzheimer disease. J. Infect. Dis. 2013, 208:564-572.
-
(2013)
J. Infect. Dis.
, vol.208
, pp. 564-572
-
-
Lurain, N.S.1
Hanson, B.A.2
Martinson, J.3
Leurgans, S.E.4
Landay, A.L.5
Bennett, D.A.6
Schneider, J.A.7
-
49
-
-
0032030581
-
Activation of human T cells with superantigen (staphylococcal enterotoxin B) and CD28 confers resistance to apoptosis via CD95
-
McLeod J.D., Walker L.S., Patel Y.I., Boulougouris G., Sansom D.M. Activation of human T cells with superantigen (staphylococcal enterotoxin B) and CD28 confers resistance to apoptosis via CD95. J. Immunol. 1998, 160:2072-2079.
-
(1998)
J. Immunol.
, vol.160
, pp. 2072-2079
-
-
McLeod, J.D.1
Walker, L.S.2
Patel, Y.I.3
Boulougouris, G.4
Sansom, D.M.5
-
50
-
-
0035915794
-
Decreased susceptibility to oxidative stress-induced apoptosis of peripheral blood mononuclear cells from healthy elderly and centenarians
-
Monti D., Salvioli S., Capri M., Malorni W., Straface E., Cossarizza A., Botti B., Piacentini M., Baggio G., Barbi C., Valensin S., Bonafe M., Franceschi C. Decreased susceptibility to oxidative stress-induced apoptosis of peripheral blood mononuclear cells from healthy elderly and centenarians. Mech. Ageing Dev. 2000, 121:239-250.
-
(2000)
Mech. Ageing Dev.
, vol.121
, pp. 239-250
-
-
Monti, D.1
Salvioli, S.2
Capri, M.3
Malorni, W.4
Straface, E.5
Cossarizza, A.6
Botti, B.7
Piacentini, M.8
Baggio, G.9
Barbi, C.10
Valensin, S.11
Bonafe, M.12
Franceschi, C.13
-
51
-
-
84889600900
-
Programmed cell senescence during mammalian embryonic development
-
Munoz-Espin D., Canamero M., Maraver A., Gomez-Lopez G., Contreras J., Murillo-Cuesta S., Rodriguez-Baeza A., Varela-Nieto I., Ruberte J., Collado M., Serrano M. Programmed cell senescence during mammalian embryonic development. Cell 2013, 155:1104-1118.
-
(2013)
Cell
, vol.155
, pp. 1104-1118
-
-
Munoz-Espin, D.1
Canamero, M.2
Maraver, A.3
Gomez-Lopez, G.4
Contreras, J.5
Murillo-Cuesta, S.6
Rodriguez-Baeza, A.7
Varela-Nieto, I.8
Ruberte, J.9
Collado, M.10
Serrano, M.11
-
52
-
-
0029993331
-
Apoptosis and the maintenance of homoeostasis in the immune system
-
Osborne B.A. Apoptosis and the maintenance of homoeostasis in the immune system. Curr. Opin. Immunol. 1996, 8:245-254.
-
(1996)
Curr. Opin. Immunol.
, vol.8
, pp. 245-254
-
-
Osborne, B.A.1
-
53
-
-
84896106344
-
Evaluating the physiological reserves of older patients with cancer: the value of potential biomarkers of aging?
-
Pallis A.G., Hatse S., Brouwers B., Pawelec G., Falandry C., Wedding U., Lago L.D., Repetto L., Ring A., Wildiers H. Evaluating the physiological reserves of older patients with cancer: the value of potential biomarkers of aging?. J. Geriatric Oncol. 2014, 5:204-218.
-
(2014)
J. Geriatric Oncol.
, vol.5
, pp. 204-218
-
-
Pallis, A.G.1
Hatse, S.2
Brouwers, B.3
Pawelec, G.4
Falandry, C.5
Wedding, U.6
Lago, L.D.7
Repetto, L.8
Ring, A.9
Wildiers, H.10
-
54
-
-
0038725685
-
Negative selection - clearing out the bad apples from the T-cell repertoire
-
Palmer E. Negative selection - clearing out the bad apples from the T-cell repertoire. Nat. Rev. Immunol. 2003, 3:383-391.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 383-391
-
-
Palmer, E.1
-
55
-
-
84922602504
-
Necroptosis and its role in inflammation
-
Pasparakis M., Vandenabeele P. Necroptosis and its role in inflammation. Nature 2015, 517:311-320.
-
(2015)
Nature
, vol.517
, pp. 311-320
-
-
Pasparakis, M.1
Vandenabeele, P.2
-
56
-
-
0030297442
-
Decreased proliferative capacity and increased susceptibility to activation-induced cell death in late-passage human CD4+ TCR2+ cultured T cell clones
-
Pawelec G., Sansom D., Rehbein A., Adibzadeh M., Beckman I. Decreased proliferative capacity and increased susceptibility to activation-induced cell death in late-passage human CD4+ TCR2+ cultured T cell clones. Exp. Gerontol. 1996, 31:655-668.
-
(1996)
Exp. Gerontol.
, vol.31
, pp. 655-668
-
-
Pawelec, G.1
Sansom, D.2
Rehbein, A.3
Adibzadeh, M.4
Beckman, I.5
-
57
-
-
84901044149
-
Inflammation, ageing and chronic disease
-
Pawelec G., Goldeck D., Derhovanessian E. Inflammation, ageing and chronic disease. Curr. Opin. Immunol. 2014, 29:23-28.
-
(2014)
Curr. Opin. Immunol.
, vol.29
, pp. 23-28
-
-
Pawelec, G.1
Goldeck, D.2
Derhovanessian, E.3
-
58
-
-
84898803220
-
Immunosenenescence: role of cytomegalovirus
-
Pawelec G. Immunosenenescence: role of cytomegalovirus. Exp. Gerontol. 2014, 54:1-5.
-
(2014)
Exp. Gerontol.
, vol.54
, pp. 1-5
-
-
Pawelec, G.1
-
59
-
-
0030981153
-
Susceptibility to apoptosis of T lymphocytes from elderly humans is associated with increased in vivo expression of functional Fas receptors
-
Phelouzat M.A., Laforge T., Arbogast A., Quadri R.A., Boutet S., Proust J.J. Susceptibility to apoptosis of T lymphocytes from elderly humans is associated with increased in vivo expression of functional Fas receptors. Mech. Ageing Dev. 1997, 96:35-46.
-
(1997)
Mech. Ageing Dev.
, vol.96
, pp. 35-46
-
-
Phelouzat, M.A.1
Laforge, T.2
Arbogast, A.3
Quadri, R.A.4
Boutet, S.5
Proust, J.J.6
-
60
-
-
8544221894
-
Balanced regulation of mRNA production for Fas and Fas ligand in lymphocytes from centenarians: how the immune system starts its second century
-
Pinti M., Troiano L., Nasi M., Bellodi C., Ferraresi R., Mussi C., Salvioli G., Cossarizza A. Balanced regulation of mRNA production for Fas and Fas ligand in lymphocytes from centenarians: how the immune system starts its second century. Circulation 2004, 110:3108-3114.
-
(2004)
Circulation
, vol.110
, pp. 3108-3114
-
-
Pinti, M.1
Troiano, L.2
Nasi, M.3
Bellodi, C.4
Ferraresi, R.5
Mussi, C.6
Salvioli, G.7
Cossarizza, A.8
-
61
-
-
84911406832
-
Increased susceptibility to oxidative death of lymphocytes from Alzheimer patients correlates with dementia severity
-
Ponce D.P., Salech F., SanMartin C.D., Silva M., Xiong C., Roe C.M., Henriquez M., Quest A.F., Behrens M.I. Increased susceptibility to oxidative death of lymphocytes from Alzheimer patients correlates with dementia severity. Curr. Alzheimer Res. 2014, 11:892-898.
-
(2014)
Curr. Alzheimer Res.
, vol.11
, pp. 892-898
-
-
Ponce, D.P.1
Salech, F.2
SanMartin, C.D.3
Silva, M.4
Xiong, C.5
Roe, C.M.6
Henriquez, M.7
Quest, A.F.8
Behrens, M.I.9
-
62
-
-
0032971440
-
Differentiation of human CD8T cells: implications for in vivo persistence of CD8+ CD28- cytotoxic effector clones
-
Posnett D.N., Edinger J.W., Manavalan J.S., Irwin C., Marodon G. Differentiation of human CD8T cells: implications for in vivo persistence of CD8+ CD28- cytotoxic effector clones. Int. Immunol. 1999, 11:229-241.
-
(1999)
Int. Immunol.
, vol.11
, pp. 229-241
-
-
Posnett, D.N.1
Edinger, J.W.2
Manavalan, J.S.3
Irwin, C.4
Marodon, G.5
-
63
-
-
0032524933
-
Apoptosis and ageing
-
Potestio M., Caruso C., Gervasi F., Scialabba G., D'Anna C., Di Lorenzo G., Balistreri C.R., Candore G., Romano G.C. Apoptosis and ageing. Mech. Ageing Dev. 1998, 102:221-237.
-
(1998)
Mech. Ageing Dev.
, vol.102
, pp. 221-237
-
-
Potestio, M.1
Caruso, C.2
Gervasi, F.3
Scialabba, G.4
D'Anna, C.5
Di Lorenzo, G.6
Balistreri, C.R.7
Candore, G.8
Romano, G.C.9
-
64
-
-
0032828528
-
Age-related changes in the expression of CD95 (APO1/FAS) on blood lymphocytes
-
Potestio M., Pawelec G., Di Lorenzo G., Candore G., D'Anna C., Gervasi F., Lio D., Tranchida G., Caruso C., Romano G.C. Age-related changes in the expression of CD95 (APO1/FAS) on blood lymphocytes. Exp. Gerontol. 1999, 34:659-673.
-
(1999)
Exp. Gerontol.
, vol.34
, pp. 659-673
-
-
Potestio, M.1
Pawelec, G.2
Di Lorenzo, G.3
Candore, G.4
D'Anna, C.5
Gervasi, F.6
Lio, D.7
Tranchida, G.8
Caruso, C.9
Romano, G.C.10
-
65
-
-
84868704447
-
Tumor-induced CD8+ T-cell dysfunction in lung cancer patients
-
Prado-Garcia H., Romero-Garcia S., Aguilar-Cazares D., Meneses-Flores M., Lopez-Gonzalez J.S. Tumor-induced CD8+ T-cell dysfunction in lung cancer patients. Clin. Dev. Immunol. 2012, 2012:741741.
-
(2012)
Clin. Dev. Immunol.
, vol.2012
, pp. 741741
-
-
Prado-Garcia, H.1
Romero-Garcia, S.2
Aguilar-Cazares, D.3
Meneses-Flores, M.4
Lopez-Gonzalez, J.S.5
-
66
-
-
0033078912
-
UVC-induced cell death of IL-2-dependent human lymphocytes
-
Radziszewska E., Piwocka K., Skierski J., Sikora E. UVC-induced cell death of IL-2-dependent human lymphocytes. Cell Biol. Int. 1999, 23:97-103.
-
(1999)
Cell Biol. Int.
, vol.23
, pp. 97-103
-
-
Radziszewska, E.1
Piwocka, K.2
Skierski, J.3
Sikora, E.4
-
67
-
-
0034567910
-
Effect of aging on UVC-induced apoptosis of rat splenocytes
-
Radziszewska E., Piwocka K., Bielak-Zmijewska A., Skierski J., Sikora E. Effect of aging on UVC-induced apoptosis of rat splenocytes. Acta Biochim. Pol. 2000, 47:339-347.
-
(2000)
Acta Biochim. Pol.
, vol.47
, pp. 339-347
-
-
Radziszewska, E.1
Piwocka, K.2
Bielak-Zmijewska, A.3
Skierski, J.4
Sikora, E.5
-
68
-
-
79951912532
-
Four faces of cellular senescence
-
Rodier F., Campisi J. Four faces of cellular senescence. J. Cell Biol. 2011, 192:547-556.
-
(2011)
J. Cell Biol.
, vol.192
, pp. 547-556
-
-
Rodier, F.1
Campisi, J.2
-
69
-
-
79953677172
-
Apoptosis and aging: increased resistance to apoptosis enhances the aging process
-
Salminen A., Ojala J., Kaarniranta K. Apoptosis and aging: increased resistance to apoptosis enhances the aging process. Cell Mol. Life Sci. 2011, 68:1021-1031.
-
(2011)
Cell Mol. Life Sci.
, vol.68
, pp. 1021-1031
-
-
Salminen, A.1
Ojala, J.2
Kaarniranta, K.3
-
70
-
-
0034282322
-
Age-related changes of apoptotic cell death in human lymphocytes
-
Schindowski K., Leutner S., Muller W.E., Eckert A. Age-related changes of apoptotic cell death in human lymphocytes. Neurobiol. Aging 2000, 21:661-670.
-
(2000)
Neurobiol. Aging
, vol.21
, pp. 661-670
-
-
Schindowski, K.1
Leutner, S.2
Muller, W.E.3
Eckert, A.4
-
71
-
-
0036151690
-
Circulating cytotoxic CD8(+) CD28(-) T cells in ankylosing spondylitis
-
Schirmer M., Goldberger C., Wurzner R., Duftner C., Pfeiffer K.P., Clausen J., Neumayr G., Falkenbach A. Circulating cytotoxic CD8(+) CD28(-) T cells in ankylosing spondylitis. Arthritis Res. 2002, 4:71-76.
-
(2002)
Arthritis Res.
, vol.4
, pp. 71-76
-
-
Schirmer, M.1
Goldberger, C.2
Wurzner, R.3
Duftner, C.4
Pfeiffer, K.P.5
Clausen, J.6
Neumayr, G.7
Falkenbach, A.8
-
72
-
-
12344265789
-
T cell subsets and mortality in older community-dwelling women
-
Semba R.D., Margolick J.B., Leng S., Walston J., Ricks M.O., Fried L.P. T cell subsets and mortality in older community-dwelling women. Exp. Gerontol. 2005, 40:81-87.
-
(2005)
Exp. Gerontol.
, vol.40
, pp. 81-87
-
-
Semba, R.D.1
Margolick, J.B.2
Leng, S.3
Walston, J.4
Ricks, M.O.5
Fried, L.P.6
-
73
-
-
78650243948
-
Impact of cellular senescence signature on ageing research
-
Sikora E., Arendt T., Bennett M., Narita M. Impact of cellular senescence signature on ageing research. Ageing Res. Rev. 2011, 10:146-152.
-
(2011)
Ageing Res. Rev.
, vol.10
, pp. 146-152
-
-
Sikora, E.1
Arendt, T.2
Bennett, M.3
Narita, M.4
-
74
-
-
84879019836
-
Rejuvenation of senescent cells-the road to postponing human aging and age-related disease?
-
Sikora E. Rejuvenation of senescent cells-the road to postponing human aging and age-related disease?. Exp. Gerontol. 2013, 48:661-666.
-
(2013)
Exp. Gerontol.
, vol.48
, pp. 661-666
-
-
Sikora, E.1
-
75
-
-
0032845553
-
Resistance to apoptosis in human CD8+ T cells that reach replicative senescence after multiple rounds of antigen-specific proliferation
-
Spaulding C., Guo W., Effros R.B. Resistance to apoptosis in human CD8+ T cells that reach replicative senescence after multiple rounds of antigen-specific proliferation. Exp. Gerontol. 1999, 34:633-644.
-
(1999)
Exp. Gerontol.
, vol.34
, pp. 633-644
-
-
Spaulding, C.1
Guo, W.2
Effros, R.B.3
-
76
-
-
0035854526
-
T cell death and memory
-
Sprent J., Tough D.F. T cell death and memory. Science 2001, 293:245-248.
-
(2001)
Science
, vol.293
, pp. 245-248
-
-
Sprent, J.1
Tough, D.F.2
-
77
-
-
84889565689
-
Senescence is a developmental mechanism that contributes to embryonic growth and patterning
-
Storer M., Mas A., Robert-Moreno A., Pecoraro M., Ortells M.C., Di Giacomo V., Yosef R., Pilpel N., Krizhanovsky V., Sharpe J., Keyes W.M. Senescence is a developmental mechanism that contributes to embryonic growth and patterning. Cell 2013, 155:1119-1130.
-
(2013)
Cell
, vol.155
, pp. 1119-1130
-
-
Storer, M.1
Mas, A.2
Robert-Moreno, A.3
Pecoraro, M.4
Ortells, M.C.5
Di Giacomo, V.6
Yosef, R.7
Pilpel, N.8
Krizhanovsky, V.9
Sharpe, J.10
Keyes, W.M.11
-
78
-
-
0028223847
-
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
-
Takahashi T., Tanaka M., Brannan C.I., Jenkins N.A., Copeland N.G., Suda T., Nagata S. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 1994, 76:969-976.
-
(1994)
Cell
, vol.76
, pp. 969-976
-
-
Takahashi, T.1
Tanaka, M.2
Brannan, C.I.3
Jenkins, N.A.4
Copeland, N.G.5
Suda, T.6
Nagata, S.7
-
80
-
-
0034544566
-
Clonality and longevity of CD4+CD28null T cells are associated with defects in apoptotic pathways
-
Vallejo A.N., Schirmer M., Weyand C.M., Goronzy J.J. Clonality and longevity of CD4+CD28null T cells are associated with defects in apoptotic pathways. J. Immunol. 2000, 165:6301-6307.
-
(2000)
J. Immunol.
, vol.165
, pp. 6301-6307
-
-
Vallejo, A.N.1
Schirmer, M.2
Weyand, C.M.3
Goronzy, J.J.4
-
81
-
-
20344379893
-
CD28 extinction in human T cells: altered functions and the program of T-cell senescence
-
Vallejo A.N. CD28 extinction in human T cells: altered functions and the program of T-cell senescence. Immunol. Rev. 2005, 205:158-169.
-
(2005)
Immunol. Rev.
, vol.205
, pp. 158-169
-
-
Vallejo, A.N.1
-
82
-
-
33947700360
-
Role of persistent CMV infection in configuring T cell immunity in the elderly
-
Vasto S., Colonna-Romano G., Larbi A., Wikby A., Caruso C., Pawelec G. Role of persistent CMV infection in configuring T cell immunity in the elderly. Immun. Ageing 2007, 4:2.
-
(2007)
Immun. Ageing
, vol.4
, pp. 2
-
-
Vasto, S.1
Colonna-Romano, G.2
Larbi, A.3
Wikby, A.4
Caruso, C.5
Pawelec, G.6
-
83
-
-
0031667566
-
Down-regulation of CD28 via Fas (CD95): influence of CD28 on T-cell apoptosis
-
Walker L.S., McLeod J.D., Boulougouris G., Patel Y.I., Hall N.D., Sansom D.M. Down-regulation of CD28 via Fas (CD95): influence of CD28 on T-cell apoptosis. Immunology 1998, 94:41-47.
-
(1998)
Immunology
, vol.94
, pp. 41-47
-
-
Walker, L.S.1
McLeod, J.D.2
Boulougouris, G.3
Patel, Y.I.4
Hall, N.D.5
Sansom, D.M.6
-
84
-
-
77953783023
-
The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasis
-
Walsh C.M., Edinger A.L. The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasis. Immunol. Rev. 2010, 236:95-109.
-
(2010)
Immunol. Rev.
, vol.236
, pp. 95-109
-
-
Walsh, C.M.1
Edinger, A.L.2
-
85
-
-
66149167336
-
DNA damage response and cellular senescence in tissues of aging mice
-
Wang C., Jurk D., Maddick M., Nelson G., Martin-Ruiz C., von Zglinicki T. DNA damage response and cellular senescence in tissues of aging mice. Aging Cell 2009, 8:311-323.
-
(2009)
Aging Cell
, vol.8
, pp. 311-323
-
-
Wang, C.1
Jurk, D.2
Maddick, M.3
Nelson, G.4
Martin-Ruiz, C.5
von Zglinicki, T.6
-
86
-
-
0033391878
-
Apoptosis: a two-edged sword in aging
-
Warner H.R. Apoptosis: a two-edged sword in aging. Ann. N. Y. Acad Sci. 1999, 887:1-11.
-
(1999)
Ann. N. Y. Acad Sci.
, vol.887
, pp. 1-11
-
-
Warner, H.R.1
-
87
-
-
33846086146
-
Is cell death and replacement a factor in aging?
-
Warner H.R. Is cell death and replacement a factor in aging?. Mech. Ageing Dev. 2007, 128:13-16.
-
(2007)
Mech. Ageing Dev.
, vol.128
, pp. 13-16
-
-
Warner, H.R.1
-
88
-
-
0026568919
-
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
-
Watanabe-Fukunaga R., Brannan C.I., Copeland N.G., Jenkins N.A., Nagata S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 1992, 356:314-317.
-
(1992)
Nature
, vol.356
, pp. 314-317
-
-
Watanabe-Fukunaga, R.1
Brannan, C.I.2
Copeland, N.G.3
Jenkins, N.A.4
Nagata, S.5
-
89
-
-
19644375921
-
Discovery, regulation, and action of the major apoptotic nucleases DFF40/CAD and endonuclease G
-
Widlak P., Garrard W.T. Discovery, regulation, and action of the major apoptotic nucleases DFF40/CAD and endonuclease G. J. Cell Biochem. 2005, 94:1078-1087.
-
(2005)
J. Cell Biochem.
, vol.94
, pp. 1078-1087
-
-
Widlak, P.1
Garrard, W.T.2
-
90
-
-
20544476197
-
An immune risk phenotype, cognitive impairment, and survival in very late life: impact of allostatic load in Swedish octogenarian and nonagenarian humans
-
Wikby A., Ferguson F., Forsey R., Thompson J., Strindhall J., Lofgren S., Nilsson B.O., Ernerudh J., Pawelec G., Johansson B. An immune risk phenotype, cognitive impairment, and survival in very late life: impact of allostatic load in Swedish octogenarian and nonagenarian humans. J. Gerontol. A Biol. Sci. Med. Sci. 2005, 60:556-565.
-
(2005)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.60
, pp. 556-565
-
-
Wikby, A.1
Ferguson, F.2
Forsey, R.3
Thompson, J.4
Strindhall, J.5
Lofgren, S.6
Nilsson, B.O.7
Ernerudh, J.8
Pawelec, G.9
Johansson, B.10
-
91
-
-
10744223612
-
Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: a contribution to understand the relationship between inflammation and immunosenescence
-
Zanni F., Vescovini R., Biasini C., Fagnoni F., Zanlari L., Telera A., Di Pede P., Passeri G., Pedrazzoni M., Passeri M., Franceschi C., Sansoni P. Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: a contribution to understand the relationship between inflammation and immunosenescence. Exp. Gerontol. 2003, 38:981-987.
-
(2003)
Exp. Gerontol.
, vol.38
, pp. 981-987
-
-
Zanni, F.1
Vescovini, R.2
Biasini, C.3
Fagnoni, F.4
Zanlari, L.5
Telera, A.6
Di Pede, P.7
Passeri, G.8
Pedrazzoni, M.9
Passeri, M.10
Franceschi, C.11
Sansoni, P.12
-
92
-
-
84874798024
-
What is the proximal cause of aging?
-
Zimniak P. What is the proximal cause of aging?. Front. Gen. 2012, 3:189.
-
(2012)
Front. Gen.
, vol.3
, pp. 189
-
-
Zimniak, P.1
-
93
-
-
45849099050
-
Living on a break: cellular senescence as a DNA-damage response
-
d'Adda di Fagagna F. Living on a break: cellular senescence as a DNA-damage response. Nat. Rev. Cancer 2008, 8:512-522.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 512-522
-
-
d'Adda di Fagagna, F.1
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