Altered T-cell subtypes in spondyloarthritis, rheumatoid arthritis and polymyalgia rheumatica

Rheumatology International

Volumn 30, Issue 3, 2010, Pages 297-303

  Dejaco, Christian ^a,b   Duftner, Christina ^a,b   Klauser, Andrea ^a   Schirmer, Michael ^a,b  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b GENERAL HOSPITAL KLAGENFURT   (Austria)

Author keywords

Polymyalgia rheumatica; Rheumatoid arthritis; Spondyloarthritis; T lymphocytes; Temporal arteritis

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD45RA ANTIGEN; CD45RO ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA;

ADULT; ANKYLOSING SPONDYLITIS; ARTICLE; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; MAJOR CLINICAL STUDY; MALE; MEMORY T LYMPHOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; REGULATORY T LYMPHOCYTE; RHEUMATIC POLYMYALGIA; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID;

ADULT; AGED; ANTIGENS, SURFACE; ARTHRITIS, RHEUMATOID; BIOLOGICAL MARKERS; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOLOGIC MEMORY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; POLYMYALGIA RHEUMATICA; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; SPONDYLITIS, ANKYLOSING; SYNOVIAL FLUID; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY;

EID: 73649125846     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00296-009-0949-9     Document Type: Article

References (50)

1. YM Kang X Zhang UG Wagner H Yang RD Beckenbaugh PJ Kurtin JJ Goronzy CM Weyand 2002 CD8 T cells are required for the formation of ectopic germinal centers in rheumatoid synovitis J Exp Med 195 1325 1336 10.1084/jem.20011565 10.1084/jem.20011565 1:CAS:528:DC%2BD38XjvFegtLw%3D 12021312 (Pubitemid 34564334)
2. S Takemura PA Klimiuk A Braun JJ Goronzy CM Weyand 2001 T cell activation in rheumatoid synovium is B cell dependent J Immunol 167 4710 4718 1:CAS:528:DC%2BD3MXns1Gls7Y%3D 11591802
3. S Takemura A Braun C Crowson PJ Kurtin RH Cofield WM O'Fallon JJ Goronzy CM Weyand 2001 Lymphoid neogenesis in rheumatoid synovitis J Immunol 167 1072 1080 1:CAS:528:DC%2BD3MXotFWktbg%3D 11441118
4. JA Byrne JL Butler MD Cooper 1988 Differential activation requirements for virgin and memory T cells J Immunol 141 3249 3257 1:STN:280: DyaL1M%2FjsFCgtA%3D%3D 2972769
5. CL Kohem RI Brezinschek H Wisbey C Tortorella PE Lipsky N Oppenheimer-Marks 1996 Enrichment of differentiated CD45RBdim, CD27- memory T cells in the peripheral blood, synovial fluid, and synovial tissue of patients with rheumatoid arthritis Arthritis Rheum 39 844 854 10.1002/art.1780390518 10.1002/art.1780390518 1:STN:280:DyaK283ht1CntA%3D%3D 8639182 (Pubitemid 26140431)
6. Y Morita M Yamamura M Kawashima S Harada K Tsuji K Shibuya K Maruyama H Makino 1998 Flow cytometric single-cell analysis of cytokine production by CD4+ T cells in synovial tissue and peripheral blood from patients with rheumatoid arthritis Arthritis Rheum 4 1669 1676 10.1002/1529-0131(199809)41:9<1669:: AID-ART19>3.0.CO;2-G 10.1002/1529-0131(199809)41:9<1669::AID-ART19>3.0. CO;2-G (Pubitemid 28459927)
7. MC Brunner-Weinzierl H Hoff GR Burmester 2004 Multiple functions for CD28 and cytotoxic T lymphocyte antigen-4 during different phases of T cell responses: implications for arthritis and autoimmune diseases Arthritis Res Ther 6 45 54 10.1186/ar1158 10.1186/ar1158 1:CAS:528:DC%2BD2cXot1Wltrg%3D 15059264
8. JM Kremer 2005 Selective costimulation modulators: a novel approach for the treatment of rheumatoid arthritis J Clin Rheumatol 11 55 62 10.1097/01.rhu.0000166626.68898.17 10.1097/01.rhu.0000166626.68898.17 (Pubitemid 40863820)
9. D Schmidt JJ Goronzy CM Weyand 1996 CD4+ CD7- CD28- T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity J Clin Invest 97 2027 2037 10.1172/JCI118638 10.1172/JCI118638 1:CAS:528:DyaK28Xislyms7Y%3D 8621791
10. JJ Goronzy CM Weyand 2001 Thymic function and peripheral T-cell homeostasis in rheumatoid arthritis Trends Immunol 22 251 255 10.1016/S1471-4906(00)01841-X 10.1016/S1471-4906(00)01841-X 1:CAS:528: DC%2BD3MXktFahu7o%3D 11323282 (Pubitemid 32667512)
11. R Tarazona O DelaRosa C Alonso B Ostos J Espejo J Pena R Solana 2000 Increased expression of NK cell markers on T lymphocytes in aging and chronic activation of the immune system reflects the accumulation of effector/senescent T cells Mech Ageing Dev 121 77 88 10.1016/S0047-6374(00)00199-8 10.1016/S0047-6374(00)00199-8 1:CAS:528:DC%2BD3MXnsVWmug%3D%3D 11164462 (Pubitemid 32115402)
12. CM Weyand JJ Goronzy 1999 T-cell responses in rheumatoid arthritis: systemic abnormalities-local disease Curr Opin Rheumatol 11 210 217 10.1097/00002281-199905000-00010 10.1097/00002281-199905000-00010 1:STN:280:DyaK1M3lvFWgsQ%3D%3D 10328581 (Pubitemid 29257639)
13. M Prelog 2006 Aging of the immune system: a risk factor for autoimmunity? Autoimmun Rev 5 136 139 10.1016/j.autrev.2005.09.008 10.1016/j.autrev.2005.09. 008 1:CAS:528:DC%2BD28XisFWqsL4%3D 16431345 (Pubitemid 43129545)
14. B Raffeiner C Dejaco C Duftner W Kullich C Goldberger SC Vega M Keller B Grubeck-Loebenstein M Schirmer 2005 Between adaptive and innate immunity: TLR4-mediated perforin production by CD28null T-helper cells in ankylosing spondylitis Arthritis Res Ther 7 R1412 R1420 10.1186/ar1840 10.1186/ar1840 1:CAS:528:DC%2BD2MXht1Wmsr%2FK 16277694
15. S Abedin JJ Michel B Lemster AN Vallejo 2005 Diversity of NKR expression in aging T cells and in T cells of the aged: the new frontier into the exploration of protective immunity in the elderly Exp Gerontol 40 537 548 10.1016/j.exger.2005.04.012 10.1016/j.exger.2005.04.012 1:CAS:528: DC%2BD2MXntVGis70%3D 16002251 (Pubitemid 41074799)
16. C Baecher-Allan JA Brown GJ Freeman DA Hafler 2001 CD4+CD25high regulatory cells in human peripheral blood J Immunol 167 1245 1253 1:CAS:528:DC%2BD3MXls1Wktbk%3D 11466340
17. D Valmori A Merlo NE Souleimanian CS Hesdorffer M Ayyoub 2005 A peripheral circulating compartment of natural naive CD4+ Tregs J Clin Invest 115 1953 1962 10.1172/JCI23963 10.1172/JCI23963 1:CAS:528:DC%2BD2MXlvF2qtLs%3D 16007258 (Pubitemid 40979735)
18. C Dejaco C Duftner B Grubeck-Loebenstein M Schirmer 2006 Imbalance of regulatory T cells in human autoimmune diseases Immunology 117 289 300 10.1111/j.1365-2567.2005.02317.x 10.1111/j.1365-2567.2005.02317.x 1:CAS:528:DC%2BD28XjtVeqsL0%3D 16476048
19. CC Su WY Shau CR Wang CY Chuang CY Chen 1997 CD69 to CD3 ratio of peripheral blood mononuclear cells as a marker to monitor systemic lupus erythematosus disease activity Lupus 6 449 454 10.1177/096120339700600507 10.1177/096120339700600507 1:STN:280:DyaK2szntlehsQ%3D%3D 9229364
20. M Dougados S van der Linden R Juhlin B Huitfeldt B Amor A Calin A Cats B Dijkmans I Olivieri G Pasero, et al. 1991 The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy Arthritis Rheum 34 1218 1227 10.1002/art.1780341003 10.1002/art.1780341003 1:STN:280:DyaK38%2FivFSqsA%3D%3D 1930310
21. FC Arnett SM Edworthy DA Bloch DJ McShane JF Fries NS Cooper LA Healey SR Kaplan MH Liang HS Luthra, et al. 1988 The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis Arthritis Rheum 31 315 324 10.1002/art.1780310302 10.1002/art.1780310302 1:STN:280: DyaL1c7pt1Ohsg%3D%3D 3358796
22. HA Bird W Esselinckx AS Dixon AG Mowat PH Wood 1979 An evaluation of criteria for polymyalgia rheumatica Ann Rheum Dis 38 434 439 10.1136/ard.38.5.434 10.1136/ard.38.5.434 1:STN:280:DyaL3c%2Fos1Khtg%3D%3D 518143
23. C Duftner C Dejaco W Kullich A Klauser C Goldberger A Falkenbach M Schirmer 2006 Preferential type 1 chemokine receptors and cytokine production of CD28- T-cells in ankylosing spondylitis Ann Rheum Dis 65 647 653 10.1136/ard.2005.042085 10.1136/ard.2005.042085 1:CAS:528:DC%2BD28XkvFyqur4%3D 16219708
24. C Duftner C Goldberger A Falkenbach R Würzner B Falkensammer KP Pfeiffer E Maerker-Hermann M Schirmer 2003 Prevalence, clinical relevance and characterization of circulating cytotoxic CD4+CD28- T cell in ankylosing spondylitis Arthritis Res Ther 5 292 300 10.1186/ar793 10.1186/ar793
25. T Namekawa MR Snyder JH Yen BE Goehring PJ Leibson CM Weyand JJ Goronzy 2000 Killer cell activating receptors function as costimulatory molecules on CD4+CD28null T cells clonally expanded in rheumatoid arthritis J Immunol 165 1138 1145 1:CAS:528:DC%2BD3cXkvFWitLg%3D 10878393
26. P Lamprecht F Moosig E Csernok U Seitzer A Schnabel A Mueller WL Gross 2001 CD28 negative T cells are enriched in granulomatous lesions of the respiratory tract in Wegener's granulomatosis Thorax 56 751 757 10.1136/thorax.56.10.751 10.1136/thorax.56.10.751 1:STN:280: DC%2BD3MrhsV2nsg%3D%3D 11562512 (Pubitemid 32917543)
27. S Markovic-Plese I Cortese KP Wandinger HF McFarland R Martin 2001 CD4+CD28- costimulation-independent T cells in multiple sclerosis J Clin Invest 108 1185 1194 1:CAS:528:DC%2BD3MXns1ChsLw%3D 11602626
28. G Liuzzo SL Kopecky RL Frye WM O'Fallon A Maseri JJ Goronzy CM Weyand 1999 Perturbation of the T-cell repertoire in patients with unstable angina Circulation 100 2135 2139 1:CAS:528:DyaK1MXotFajsbc%3D 10571971
29. C Duftner R Seiler P Klein-Weigel H Gobel C Goldberger C Ihling G Fraedrich M Schirmer 2005 High prevalence of circulating CD4+CD28- T-cells in patients with small abdominal aortic aneurysms Arterioscler Thromb Vasc Biol 25 1347 1352 10.1161/01.ATV.0000167520.41436.c0 10.1161/01.ATV.0000167520.41436.c0 1:CAS:528:DC%2BD2MXltlSis78%3D 15845908 (Pubitemid 40923350)
30. T Nakajima S Schulte KJ Warrington SL Kopecky RL Frye JJ Goronzy CM Weyand 2002 T-cell-mediated lysis of endothelial cells in acute coronary syndromes Circulation 105 570 575 10.1161/hc0502.103348 10.1161/hc0502.103348 1:CAS:528:DC%2BD38XhslGiu7g%3D 11827921 (Pubitemid 34123430)
31. PB Martens JJ Goronzy D Schaid CM Weyand 1997 Expansion of unusual CD4+T cells in severe rheumatoid arthritis Arthritis Rheum 40 1106 1114 10.1002/art.1780400615 10.1002/art.1780400615 1:CAS:528:DyaK2sXktV2qt74%3D 9182921 (Pubitemid 27242298)
32. JJ Goronzy EL Matteson JW Fulbright KJ Warrington A Chang-Miller GG Hunder TG Mason AM Nelson RM Valente CS Crowson HA Erlich RL Reynolds RG Swee WM O'Fallon CM Weyand 2004 Prognostic markers of radiographic progression in early rheumatoid arthritis Arthritis Rheum 50 43 54 10.1002/art.11445 10.1002/art.11445 14730598 (Pubitemid 38084286)
33. R Gerli G Schillaci A Giordano EB Bocci O Bistoni G Vaudo S Marchesi M Pirro F Ragni Y Shoenfeld E Mannarino 2004 CD4+CD28- T lymphocytes contribute to early atherosclerotic damage in rheumatoid arthritis patients Circulation 109 2744 2748 10.1161/01.CIR.0000131450.66017.B3 10.1161/01.CIR.0000131450.66017.B3 1:CAS:528:DC%2BD2cXksVKgtb0%3D 15159291 (Pubitemid 38737922)
34. KJ Warrington PD Kent RL Frye JF Lymp SL Kopecky JJ Goronzy CM Weyand 2005 Rheumatoid arthritis is an independent risk factor for multi-vessel coronary artery disease: a case control study Arthritis Res Ther 7 R984 R991 10.1186/ar1775 10.1186/ar1775 1:CAS:528:DC%2BD2MXpvFOgu7c%3D 16207339
35. S Gupta R Bi K Su L Yel S Chiplunkar S Gollapudi 2004 Characterization of naive, memory and effector CD8+ T cells: effect of age Exp Gerontol 39 545 550 10.1016/j.exger.2003.08.013 10.1016/j.exger.2003.08.013 1:CAS:528: DC%2BD2cXisF2nurg%3D 15050289 (Pubitemid 38402081)
36. E Davila YM Kang YW Park H Sawai X He S Pryshchep JJ Goronzy CM Weyand 2005 Cell-based immunotherapy with suppressor CD8+ T cells in rheumatoid arthritis J Immunol 174 7292 7301 1:CAS:528:DC%2BD2MXkt1Olsro%3D 15905576
37. JJ Goronzy JW Fulbright CS Crowson GA Poland WM O'Fallon CM Weyand 2001 Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals J Virol 75 12182 12187 10.1128/JVI.75.24. 12182-12187.2001 10.1128/JVI.75.24.12182-12187.2001 1:CAS:528: DC%2BD3MXovVygt78%3D 11711609 (Pubitemid 33115891)
38. M Saurwein-Teissl TL Lung F Marx C Gschosser E Asch I Blasko W Parson G Böck D Schönitzer E Trannoy B Grubeck-Loebenstein 2002 Lack of antibody production following immunization in old age: association with CD8(+)CD28(-) T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines J Immunol 168 5893 5899 1:CAS:528:DC%2BD38XktFCrtLk%3D 12023394
39. R Ciubotariu R Vasilescu E Ho P Cinti C Cancedda L Poli M Late Z Liu P Berloco R Cortesini N Suciu-Foca Cortesini 2001 Detection of T suppressor cells in patients with organ allografts Hum Immunol 62 15 20 10.1016/S0198-8859(00) 00226-3 10.1016/S0198-8859(00)00226-3 1:CAS:528:DC%2BD3MXpsV2gtg%3D%3D 11165711 (Pubitemid 32163930)
40. SO Schonland C Lopez T Widmann J Zimmer E Bryl JJ Goronzy CM Weyand 2003 Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages Proc Natl Acad Sci USA 100 13471 13476 10.1073/pnas.2233561100 10.1073/pnas.2233561100 14578453 (Pubitemid 37444766)
41. K Koetz E Bryl K Spickschen WM O'Fallon JJ Goronzy CM Weyand 2000 T cell homeostasis in patients with rheumatoid arthritis Proc Natl Acad Sci USA 97 9203 9208 10.1073/pnas.97.16.9203 10.1073/pnas.97.16.9203 1:CAS:528: DC%2BD3cXls12ksLk%3D 10922071 (Pubitemid 30626698)
42. E Amyes AJ McMichael MF Callan 2005 Human CD4+ T cells are predominantly distributed among six phenotypically and functionally distinct subsets J Immunol 175 5765 5773 1:CAS:528:DC%2BD2MXhtFahurvL 16237068
43. D Cao R van Vollenhoven L Klareskog C Trollmo V Malmstrom 2004 CD25bright CD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease Arthritis Res Ther 6 R335 R346 10.1186/ar1192 10.1186/ar1192 1:CAS:528:DC%2BD2cXmt1Gls7Y%3D 15225369
44. MF Liu CR Wang LL Fung CR Wu 2004 Decreased CD4+CD25+ T cells in peripheral blood of patients with systemic lupus erythematosus Scand J Immunol 59 198 202 10.1111/j.0300-9475.2004.01370.x 10.1111/j.0300-9475.2004.01370.x 14871297 (Pubitemid 38253553)
45. JM van Amelsfort KM Jacobs JW Bijlsma FP Lafeber LS Taams 2004 CD4+CD25+ regulatory T cells in rheumatoid arthritis Arthritis Rheum 50 2775 2785 10.1002/art.20499 10.1002/art.20499 15457445 (Pubitemid 39209514)
46. D Cao V Malmstrom C Baecher-Allan D Hafler L Klareskog C Trollmo 2003 Isolation and functional characterization of regulatory CD25bright CD4+ T cells from the target organ of patients with rheumatoid arthritis Eur J Immunol 33 215 223 10.1002/immu.200390024 10.1002/immu.200390024 1:CAS:528: DC%2BD3sXos1SltA%3D%3D 12594850 (Pubitemid 36157659)
47. MR Ehrenstein JG Evans A Singh S Moore G Warnes DA Isenberg C Mauri 2004 Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy J Exp Med 200 277 285 10.1084/jem.20040165 10.1084/jem.20040165 1:CAS:528:DC%2BD2cXmsVCktbg%3D 15280421 (Pubitemid 39031247)
48. M Mottonen J Heikkinen L Mustonen P Isomaki R Luukkainen O Lassila 2005 CD4+CD25+ T cells with the phenotypic and functional characteristics of regulatory T cells are enriched in the synovial fluid of patients with rheumatoid arthritis Clin Exp Immunol 140 360 367 10.1111/j.1365-2249.2005. 02754.x 10.1111/j.1365-2249.2005.02754.x 1:STN:280:DC%2BD2M7nsFyisw%3D%3D 15807863 (Pubitemid 40559165)
49. A Suarez P Lopez J Gomez C Gutierrez 2006 Enrichment of CD4+CD25high T cell population in SLE patients treated with glucocorticoids Ann Rheum Dis 65 1512 1517 10.1136/ard.2005.049924 10.1136/ard.2005.049924 1:CAS:528: DC%2BD28Xht1OjtLrM 16606650 (Pubitemid 44629132)
50. C Dejaco C Duftner M Schirmer 2006 Are regulatory T-cells linked with aging? Exp Gerontol 41 339 345 10.1016/j.exger.2006.01.008 10.1016/j.exger.2006. 01.008 1:CAS:528:DC%2BD28XksVOhtbg%3D 16516426