Resistance to apoptosis in human CD8+ T cells that reach replicative senescence after multiple rounds of antigen-specific proliferation

Experimental Gerontology

Volumn 34, Issue 5, 1999, Pages 633-644

  Spaulding, Carolyn ^a   Guo, Wei ^a   Effros, Rita B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis; Cellular proliferation; Human; Replicative senescence; T lymphocytes

Indexed keywords

ANTIGEN; CASPASE 3; CD28 ANTIGEN; CD8 ANTIGEN; FAS ANTIGEN; GALECTIN; HEAT SHOCK PROTEIN; INTERLEUKIN 2; MONOCLONAL ANTIBODY; OKT 3; PROTEIN KINASE C INHIBITOR; STAUROSPORINE; TELOMERASE;

ANTIGEN SPECIFICITY; APOPTOSIS; ARTICLE; CELL AGING; CONTROLLED STUDY; ENZYME ACTIVITY; HEAT SHOCK; HUMAN; HUMAN CELL; LYMPHOCYTE CULTURE; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; TELOMERE;

APOPTOSIS; CASPASE 3; CASPASES; CD8-POSITIVE T-LYMPHOCYTES; CELL AGING; CELL DIVISION; CELLS, CULTURED; HUMANS; LYMPHOCYTE ACTIVATION; TIME FACTORS;

EID: 0032845553     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(99)00033-9     Document Type: Article

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