T cell receptor-mediated activation is a potent inducer of macroautophagy in human CD8+CD28+ T cells but not in CD8+CD28- T cells

Experimental Gerontology

Volumn 54, Issue , 2014, Pages 75-83

  Arnold, Christoph R ^a   Pritz, Theresa ^a   Brunner, Stefan ^a   Knabb, Carina ^a   Salvenmoser, Willi ^a   Holzwarth, Birgit ^b   Thedieck, Kathrin ^b,c   Grubeck Loebenstein, Beatrix ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Aging; Autophagy; CD28; Human; MTOR; T cells

Indexed keywords

CD28 ANTIGEN; IMMUNOSUPPRESSIVE AGENT; LYMPHOCYTE ANTIGEN RECEPTOR; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; RAPAMYCIN; TARGET OF RAPAMYCIN KINASE;

AGED; AUTOPHAGY; CD8+ T LYMPHOCYTE; CELL CULTURE; FEMALE; FLOW CYTOMETRY; HUMAN; MALE; METABOLISM; MONONUCLEAR CELL; PHYSIOLOGY;

AGED; ANTIGENS, CD28; AUTOPHAGY; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LEUKOCYTES, MONONUCLEAR; MALE; MULTIPROTEIN COMPLEXES; RECEPTORS, ANTIGEN, T-CELL; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84898879369     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2014.01.018     Document Type: Article

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