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Volumn 96, Issue 1-3, 1997, Pages 35-46

Susceptibility to apoptosis of T lymphocytes from elderly humans is associated with increased in vivo expression of functional Fas receptors

Author keywords

Aging; Apoptosis; Cell activation; Fas receptor; Human T lymphocytes

Indexed keywords

CD45 ANTIGEN; CD69 ANTIGEN; DNA FRAGMENT; FAS ANTIGEN; IMMUNOGLOBULIN M; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR;

EID: 0030981153     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0047-6374(97)01883-6     Document Type: Article
Times cited : (67)

References (38)
  • 2
    • 0030591595 scopus 로고    scopus 로고
    • Age-related tyrosine-specific phosphorylation defect in human lymphocytes activated through CD3, CD4, CD8 or the IL-2 receptor
    • R.A. Quadri, O. Plastre, M.-A. Phelouzat, A. Arbogast and Jacques J. Proust, Age-related tyrosine-specific phosphorylation defect in human lymphocytes activated through CD3, CD4, CD8 or the IL-2 receptor. Mech. Ageing. Dev., 88 (1996) 125-138.
    • (1996) Mech. Ageing. Dev. , vol.88 , pp. 125-138
    • Quadri, R.A.1    Plastre, O.2    Phelouzat, M.-A.3    Arbogast, A.4    Proust, J.J.5
  • 3
    • 0029988530 scopus 로고    scopus 로고
    • Age-related reductions in the activation of mitogen-activated protein kinase p44 (mapk)/ERK1 and p42 (mapk)/ERK2 in human T cells stimulated via ligation of the T cell receptor complex
    • R.L. Whisler, Y.G. Newhouse, S.E. Bagenstose, Age-related reductions in the activation of mitogen-activated protein kinase p44 (mapk)/ERK1 and p42 (mapk)/ERK2 in human T cells stimulated via ligation of the T cell receptor complex. Cell Immunol., 168 (1996) 201-210.
    • (1996) Cell Immunol. , vol.168 , pp. 201-210
    • Whisler, R.L.1    Newhouse, Y.G.2    Bagenstose, S.E.3
  • 4
    • 0023200924 scopus 로고
    • Age-related defect in signal transduction during lectin activation of murine T lymphocytes
    • J.J. Proust, C.R. Filburn, S.A. Harrisson, M.A. Buchholz and A.A. Nordin, Age-related defect in signal transduction during lectin activation of murine T lymphocytes. J. Immunol., 139 (1987) 1472-1478.
    • (1987) J. Immunol. , vol.139 , pp. 1472-1478
    • Proust, J.J.1    Filburn, C.R.2    Harrisson, S.A.3    Buchholz, M.A.4    Nordin, A.A.5
  • 5
    • 0025253398 scopus 로고
    • Decreased steady-state c-myc mRNa in activated T cell cultures from old humans is caused by a smaller proportion of T cells that transcribe the c-myc gene
    • D.A. Gamble, R. Schwab, M.E. Weksler and P. Szabo, Decreased steady-state c-myc mRNA in activated T cell cultures from old humans is caused by a smaller proportion of T cells that transcribe the c-myc gene. J. Immunol., 144 (1990) 3569-3573.
    • (1990) J. Immunol. , vol.144 , pp. 3569-3573
    • Gamble, D.A.1    Schwab, R.2    Weksler, M.E.3    Szabo, P.4
  • 6
    • 0026508422 scopus 로고
    • Phytohemagglutinin-induced changes of membrane lipid packing, c-myc and c-myb encoded protein expression in human lymphocytes during aging
    • C. Pieri, R. Recchioni, F. Moroni, F. Marcheselli and G. Lipponi, Phytohemagglutinin-induced changes of membrane lipid packing, c-myc and c-myb encoded protein expression in human lymphocytes during aging. Mech. Ageing Dev., 64 (1992) 177-187.
    • (1992) Mech. Ageing Dev. , vol.64 , pp. 177-187
    • Pieri, C.1    Recchioni, R.2    Moroni, F.3    Marcheselli, F.4    Lipponi, G.5
  • 8
    • 0029935914 scopus 로고    scopus 로고
    • Age-related decrease in IL-2 production by human T cells are associated with impaired activation of nuclear transcription factors AP-1 and NF-AT
    • R.L. Whisler, B.Q. Liu and M. Chen, Age-related decrease in IL-2 production by human T cells are associated with impaired activation of nuclear transcription factors AP-1 and NF-AT. Cell. Immunol., 169 (1996) 185-195.
    • (1996) Cell. Immunol. , vol.169 , pp. 185-195
    • Whisler, R.L.1    Liu, B.Q.2    Chen, M.3
  • 9
    • 0023950743 scopus 로고
    • Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors
    • J.E. Nagel, R.K. Choppra, F.J. Chrest, M.T. McCoy, E.L. Schneider, N.J. Holbrook and W.H. Adler, Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors. J. Clin. Invest., 81 (1988) 1096-1102.
    • (1988) J. Clin. Invest. , vol.81 , pp. 1096-1102
    • Nagel, J.E.1    Choppra, R.K.2    Chrest, F.J.3    McCoy, M.T.4    Schneider, E.L.5    Holbrook, N.J.6    Adler, W.H.7
  • 10
    • 0024207035 scopus 로고
    • Restricted expression of mitogen-induced high affinity IL-2 receptors in aging mice
    • J.J. Proust, D.S. Kittur, M.A. Buchholz and A.A. Nordin, Restricted expression of mitogen-induced high affinity IL-2 receptors in aging mice. J. Immunol., 141 (1988) 4902-4916.
    • (1988) J. Immunol. , vol.141 , pp. 4902-4916
    • Proust, J.J.1    Kittur, D.S.2    Buchholz, M.A.3    Nordin, A.A.4
  • 12
    • 0030009805 scopus 로고    scopus 로고
    • Excessive apoptosis of mature T lymphocytes is a characteristic feature of human immune senescence
    • M.-A. Phelouzat, A. Arbogast, T. Laforge, R.A. Quadri and J.J. Proust, Excessive apoptosis of mature T lymphocytes is a characteristic feature of human immune senescence. Mech. Ageing Dev., 88 (1996) 25-38.
    • (1996) Mech. Ageing Dev. , vol.88 , pp. 25-38
    • Phelouzat, M.-A.1    Arbogast, A.2    Laforge, T.3    Quadri, R.A.4    Proust, J.J.5
  • 14
    • 0026482756 scopus 로고
    • Induction of apoptosis by monoclonal antibody anti-APO-1 class switch variants is dependent on cross-linking of APO-1 cell surface antigens
    • J. Dhein, P.T. Daniel, B.C. Trauth, A. Oehm, P. Moller and P.H. Krammer, Induction of apoptosis by monoclonal antibody anti-APO-1 class switch variants is dependent on cross-linking of APO-1 cell surface antigens. J. Immunol., 149 (1992) 3116-3173.
    • (1992) J. Immunol. , vol.149 , pp. 3116-3173
    • Dhein, J.1    Daniel, P.T.2    Trauth, B.C.3    Oehm, A.4    Moller, P.5    Krammer, P.H.6
  • 16
    • 0028097822 scopus 로고
    • Purification and characterization of the Fas-ligand that induces apoptosis
    • T. Suda and S. Nagata, Purification and characterization of the Fas-ligand that induces apoptosis. J. Exp. Med., 179 (1994) 873-879.
    • (1994) J. Exp. Med. , vol.179 , pp. 873-879
    • Suda, T.1    Nagata, S.2
  • 18
    • 0028149786 scopus 로고
    • Checkpoints of dueling dimers foil death wishes
    • Z.N. Oltvai and S.J. Korsmeyer, Checkpoints of dueling dimers foil death wishes. Cell, 19 (1994) 189-192.
    • (1994) Cell , vol.19 , pp. 189-192
    • Oltvai, Z.N.1    Korsmeyer, S.J.2
  • 19
    • 0028802845 scopus 로고
    • Fas and FasL in the homeostatic regulation of immune responses
    • D.H. Lynch, F. Ramsdell and M.R. Alderson, Fas and FasL in the homeostatic regulation of immune responses. Immunol. Today, 16 (1995) 569-574.
    • (1995) Immunol. Today , vol.16 , pp. 569-574
    • Lynch, D.H.1    Ramsdell, F.2    Alderson, M.R.3
  • 21
    • 0018140454 scopus 로고
    • 'Panning' for lymphocytes: A method for cell selection
    • L.J. Wysocki and V.L. Sato, 'Panning' for lymphocytes: A method for cell selection. Proc. Natl. Acad. Sci. USA, 75 (1978) 2844-2848.
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 2844-2848
    • Wysocki, L.J.1    Sato, V.L.2
  • 22
    • 0024596722 scopus 로고
    • A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor for tumor necrosis factor
    • S. Yonehara, A. Ishii and M. Yonehara, A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor for tumor necrosis factor. J. Exp. Med., 169 (1989) 1747-1756.
    • (1989) J. Exp. Med. , vol.169 , pp. 1747-1756
    • Yonehara, S.1    Ishii, A.2    Yonehara, M.3
  • 24
    • 0026568919 scopus 로고
    • Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
    • R. Watanabe-Fukunaga, C.I. Brannan, N.G. Copeland, N.A. Jenkins and S. Nagata, Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature, 356 (1992) 314-317.
    • (1992) Nature , vol.356 , pp. 314-317
    • Watanabe-Fukunaga, R.1    Brannan, C.I.2    Copeland, N.G.3    Jenkins, N.A.4    Nagata, S.5
  • 27
    • 0029061537 scopus 로고
    • Prevention of age-related T cell apoptosis defect in CD2-Fas-transgenic mice
    • T. Zhou, C.K. Edwards III and J.D. Mountz, Prevention of age-related T cell apoptosis defect in CD2-Fas-transgenic mice. J. Exp. Med., 182 (1995) 129-137.
    • (1995) J. Exp. Med. , vol.182 , pp. 129-137
    • Zhou, T.1    Edwards C.K. III2    Mountz, J.D.3
  • 28
    • 0028670386 scopus 로고
    • Physiological T-Cell death: Susceptibility is modulated by activation, aging and transformation, but the mechanism is constant
    • D.S. Ucker, L.D. Hebshi, J.F. Bloomquist and B.E. Torbett, Physiological T-Cell death: Susceptibility is modulated by activation, aging and transformation, but the mechanism is constant. Immunol. Rev., 142 (1994) 273-299.
    • (1994) Immunol. Rev. , vol.142 , pp. 273-299
    • Ucker, D.S.1    Hebshi, L.D.2    Bloomquist, J.F.3    Torbett, B.E.4
  • 30
    • 0028129894 scopus 로고
    • Effect of the lpr mutation on elimination and inactivation of self-reactive B cells
    • J.C. Rathmell and C.C. Goodnow, Effect of the lpr mutation on elimination and inactivation of self-reactive B cells. J. Immunol., 153 (1994) 2831-2842.
    • (1994) J. Immunol. , vol.153 , pp. 2831-2842
    • Rathmell, J.C.1    Goodnow, C.C.2
  • 31
    • 0028330345 scopus 로고
    • Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus
    • W. Emlen, J. Niebur and R. Kadera, Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus. J. Immunol., 152 (1994) 3685-3692.
    • (1994) J. Immunol. , vol.152 , pp. 3685-3692
    • Emlen, W.1    Niebur, J.2    Kadera, R.3
  • 32
    • 0343883673 scopus 로고
    • + T cells in autoimmune hepatitis and chronic hepatitis type C associated with autoimmune phenomena
    • + T cells in autoimmune hepatitis and chronic hepatitis type C associated with autoimmune phenomena. Hepatology, 20 (1994) 193.
    • (1994) Hepatology , vol.20 , pp. 193
    • Ogawa, S.1    Sakaguchi, K.2    Takaki, A.3    Shiraga, K.4
  • 34
    • 0026497684 scopus 로고
    • Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood
    • T. Miyawaki, T. Uehara, R. Nibu, T. Tsuji, A. Yachie, S. Yonehara and N. Taniguchi, Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood. J. Immunol., 149 (1992) 3753-3758.
    • (1992) J. Immunol. , vol.149 , pp. 3753-3758
    • Miyawaki, T.1    Uehara, T.2    Nibu, R.3    Tsuji, T.4    Yachie, A.5    Yonehara, S.6    Taniguchi, N.7
  • 35
    • 0028080739 scopus 로고
    • The CD69 receptor: A multipurpose cell-surface trigger for hematopoietic cells
    • R. Testi, D. D'Ambrosio, R. De Maria and A. Santoni, The CD69 receptor: A multipurpose cell-surface trigger for hematopoietic cells. Immunol. Today, 15 (1994) 479-483.
    • (1994) Immunol. Today , vol.15 , pp. 479-483
    • Testi, R.1    D'Ambrosio, D.2    De Maria, R.3    Santoni, A.4
  • 36
    • 0027132028 scopus 로고
    • A comprehensive analysis of peripheral blood lymphocytes in healthy aged human by flow cytometry
    • X.N. Xu, I. Beckman, M. Ahern and J. Bradley, A comprehensive analysis of peripheral blood lymphocytes in healthy aged human by flow cytometry. Immun. Cell. Biol., 71 (1993) 549-557.
    • (1993) Immun. Cell. Biol. , vol.71 , pp. 549-557
    • Xu, X.N.1    Beckman, I.2    Ahern, M.3    Bradley, J.4
  • 38
    • 0028670374 scopus 로고
    • Fas antigen and sphingomyelin-ceramide turnover-mediated signalling: Role in life and death of T lymphocytes
    • B.M. Gill, H. Nishikata, G. Chan, T.L. Delovitch and A. Ochi, Fas antigen and sphingomyelin-ceramide turnover-mediated signalling: Role in life and death of T lymphocytes. Immunol. Rev., 142 (1994) 113-125.
    • (1994) Immunol. Rev. , vol.142 , pp. 113-125
    • Gill, B.M.1    Nishikata, H.2    Chan, G.3    Delovitch, T.L.4    Ochi, A.5


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