-
1
-
-
77949424341
-
Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients
-
Agarwal S., Loh Y.H., McLoughlin E.M., Huang J., Park I.H., Miller J.D., Huo H., Okuka M., Dos Reis R.M., Loewer S., Ng H.H., Keefe D.L., Goldman F.D., Klingelhutz A.J., Liu L., Daley G.Q. Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients. Nature 2010, 464:292-296.
-
(2010)
Nature
, vol.464
, pp. 292-296
-
-
Agarwal, S.1
Loh, Y.H.2
McLoughlin, E.M.3
Huang, J.4
Park, I.H.5
Miller, J.D.6
Huo, H.7
Okuka, M.8
Dos Reis, R.M.9
Loewer, S.10
Ng, H.H.11
Keefe, D.L.12
Goldman, F.D.13
Klingelhutz, A.J.14
Liu, L.15
Daley, G.Q.16
-
2
-
-
33744485564
-
Curcumin's biphasic hormetic response on proteasome activity and heat-shock protein synthesis in human keratinocytes
-
Ali R.E., Rattan S.I. Curcumin's biphasic hormetic response on proteasome activity and heat-shock protein synthesis in human keratinocytes. Ann. N. Y. Acad. Sci. 2006, 1067:394-399.
-
(2006)
Ann. N. Y. Acad. Sci.
, vol.1067
, pp. 394-399
-
-
Ali, R.E.1
Rattan, S.I.2
-
4
-
-
80855138775
-
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
-
Baker D.J., Wijshake T., Tchkonia T., LeBrasseur N.K., Childs B.G., van de Sluis B., Kirkland J.L., van Deursen J.M. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature 2011, 479:232-236.
-
(2011)
Nature
, vol.479
, pp. 232-236
-
-
Baker, D.J.1
Wijshake, T.2
Tchkonia, T.3
LeBrasseur, N.K.4
Childs, B.G.5
van de Sluis, B.6
Kirkland, J.L.7
van Deursen, J.M.8
-
5
-
-
80655140442
-
Progeria, rapamycin and normal aging: recent breakthrough
-
Blagosklonny M.V. Progeria, rapamycin and normal aging: recent breakthrough. Aging (Albany NY) 2011, 3:685-691.
-
(2011)
Aging (Albany NY)
, vol.3
, pp. 685-691
-
-
Blagosklonny, M.V.1
-
6
-
-
22944488871
-
Telomeres and human disease: ageing, cancer and beyond
-
Blasco M.A. Telomeres and human disease: ageing, cancer and beyond. Nat. Rev. Genet. 2005, 6:611-622.
-
(2005)
Nat. Rev. Genet.
, vol.6
, pp. 611-622
-
-
Blasco, M.A.1
-
7
-
-
0034595212
-
EMBO WORKSHOP REPORT: molecular and cellular gerontology Serpiano, Switzerland, September 18-22, 1999
-
Brack C., Lithgow G., Osiewacz H., Toussaint O. EMBO WORKSHOP REPORT: molecular and cellular gerontology Serpiano, Switzerland, September 18-22, 1999. EMBO J. 2000, 19:1929-1934.
-
(2000)
EMBO J.
, vol.19
, pp. 1929-1934
-
-
Brack, C.1
Lithgow, G.2
Osiewacz, H.3
Toussaint, O.4
-
8
-
-
84864018624
-
Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8(+) T cells sensitizing them to apoptotic cell death
-
Brunner S., Herndler-Brandstetter D., Arnold C.R., Wiegers G.J., Villunger A., Hackl M., Grillari J., Moreno-Villanueva M., Burkle A., Grubeck-Loebenstein B. Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8(+) T cells sensitizing them to apoptotic cell death. Aging Cell 2012, 4:579-587.
-
(2012)
Aging Cell
, vol.4
, pp. 579-587
-
-
Brunner, S.1
Herndler-Brandstetter, D.2
Arnold, C.R.3
Wiegers, G.J.4
Villunger, A.5
Hackl, M.6
Grillari, J.7
Moreno-Villanueva, M.8
Burkle, A.9
Grubeck-Loebenstein, B.10
-
9
-
-
0037396242
-
Proliferation of CD8+ in culture of human T cells derived from peripheral blood of adult donors and cord blood of newborns
-
Brzezinska A., Magalska A., Sikora E. Proliferation of CD8+ in culture of human T cells derived from peripheral blood of adult donors and cord blood of newborns. Mech. Ageing Dev. 2003, 124:379-387.
-
(2003)
Mech. Ageing Dev.
, vol.124
, pp. 379-387
-
-
Brzezinska, A.1
Magalska, A.2
Sikora, E.3
-
10
-
-
77954950116
-
Progeria syndromes and ageing: what is the connection?
-
Burtner C.R., Kennedy B.K. Progeria syndromes and ageing: what is the connection?. Nat. Rev. Mol. Cell Biol. 2012, 11:567-578.
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 567-578
-
-
Burtner, C.R.1
Kennedy, B.K.2
-
11
-
-
77957794662
-
Pathophysiology of vascular calcification: pivotal role of cellular senescence in vascular smooth muscle cells
-
Burton D.G., Matsubara H., Ikeda K. Pathophysiology of vascular calcification: pivotal role of cellular senescence in vascular smooth muscle cells. Exp. Gerontol. 2010, 45:819-824.
-
(2010)
Exp. Gerontol.
, vol.45
, pp. 819-824
-
-
Burton, D.G.1
Matsubara, H.2
Ikeda, K.3
-
12
-
-
0035500487
-
Cellular senescence as a tumor-suppressor mechanism
-
Campisi J. Cellular senescence as a tumor-suppressor mechanism. Trends Cell Biol. 2001, 11:S27-S31.
-
(2001)
Trends Cell Biol.
, vol.11
-
-
Campisi, J.1
-
13
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors
-
Campisi J. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 2005, 120:513-522.
-
(2005)
Cell
, vol.120
, pp. 513-522
-
-
Campisi, J.1
-
14
-
-
80855128461
-
Cellular senescence: a link between cancer and age-related degenerative disease?
-
Campisi J., Andersen J.K., Kapahi P., Melov S. Cellular senescence: a link between cancer and age-related degenerative disease?. Semin. Cancer Biol. 2011, 21:354-359.
-
(2011)
Semin. Cancer Biol.
, vol.21
, pp. 354-359
-
-
Campisi, J.1
Andersen, J.K.2
Kapahi, P.3
Melov, S.4
-
15
-
-
79959776029
-
Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells
-
Cao K., Graziotto J.J., Blair C.D., Mazzulli J.R., Erdos M.R., Krainc D., Collins F.S. Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells. Sci. Transl. Med. 2011, 3:89ra58.
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Cao, K.1
Graziotto, J.J.2
Blair, C.D.3
Mazzulli, J.R.4
Erdos, M.R.5
Krainc, D.6
Collins, F.S.7
-
16
-
-
44649095065
-
Unexpected pieces to the senescence puzzle
-
Cichowski K., Hahn W.C. Unexpected pieces to the senescence puzzle. Cell 2008, 133:958-961.
-
(2008)
Cell
, vol.133
, pp. 958-961
-
-
Cichowski, K.1
Hahn, W.C.2
-
17
-
-
45849099050
-
Living on a break: cellular senescence as a DNA-damage response
-
d'Adda di Fagagna F. Living on a break: cellular senescence as a DNA-damage response. Nat. Rev. Cancer 2008, 8:512-522.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 512-522
-
-
d'Adda di Fagagna, F.1
-
18
-
-
77954563804
-
Senescent cells as a source of inflammatory factors for tumor progression
-
Davalos A.R., Coppe J.P., Campisi J., Desprez P.Y. Senescent cells as a source of inflammatory factors for tumor progression. Cancer Metastasis Rev. 2010, 29:273-283.
-
(2010)
Cancer Metastasis Rev.
, vol.29
, pp. 273-283
-
-
Davalos, A.R.1
Coppe, J.P.2
Campisi, J.3
Desprez, P.Y.4
-
20
-
-
58849155179
-
Vascular endothelial senescence: from mechanisms to pathophysiology
-
Erusalimsky J.D. Vascular endothelial senescence: from mechanisms to pathophysiology. J. Appl. Physiol. 2009, 106:326-332.
-
(2009)
J. Appl. Physiol.
, vol.106
, pp. 326-332
-
-
Erusalimsky, J.D.1
-
21
-
-
34147096369
-
Systemic inflammation, infection, ApoE alleles, and Alzheimer disease: a position paper
-
Finch C.E., Morgan T.E. Systemic inflammation, infection, ApoE alleles, and Alzheimer disease: a position paper. Curr Alzheimer Res. 2007, 4:185-189.
-
(2007)
Curr Alzheimer Res.
, vol.4
, pp. 185-189
-
-
Finch, C.E.1
Morgan, T.E.2
-
22
-
-
0033911488
-
Inflamm-aging. An evolutionary perspective on immunosenescence
-
Franceschi C., Bonafe M., Valensin S., Olivieri F., De Luca M., Ottaviani E., De Benedictis G. Inflamm-aging. An evolutionary perspective on immunosenescence. Ann. N. Y. Acad. Sci. 2000, 908:244-254.
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.908
, pp. 244-254
-
-
Franceschi, C.1
Bonafe, M.2
Valensin, S.3
Olivieri, F.4
De Luca, M.5
Ottaviani, E.6
De Benedictis, G.7
-
23
-
-
19544383551
-
Senescence and its bypass in the vascular endothelium
-
Freedman D.A. Senescence and its bypass in the vascular endothelium. Front. Biosci. 2005, 10:940-950.
-
(2005)
Front. Biosci.
, vol.10
, pp. 940-950
-
-
Freedman, D.A.1
-
24
-
-
53649109801
-
Critical pathways in cellular senescence and immortalization revealed by gene expression profiling
-
Fridman A.L., Tainsky M.A. Critical pathways in cellular senescence and immortalization revealed by gene expression profiling. Oncogene 2008, 27:5975-5987.
-
(2008)
Oncogene
, vol.27
, pp. 5975-5987
-
-
Fridman, A.L.1
Tainsky, M.A.2
-
25
-
-
84859372986
-
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation
-
Fumagalli M., Rossiello F., Clerici M., Barozzi S., Cittaro D., Kaplunov J.M., Bucci G., Dobreva M., Matti V., Beausejour C.M., Herbig U., Longhese M.P., d'Adda di Fagagna F. Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. Nat. Cell Biol. 2012, 14:355-365.
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 355-365
-
-
Fumagalli, M.1
Rossiello, F.2
Clerici, M.3
Barozzi, S.4
Cittaro, D.5
Kaplunov, J.M.6
Bucci, G.7
Dobreva, M.8
Matti, V.9
Beausejour, C.M.10
Herbig, U.11
Longhese, M.P.12
d'Adda di Fagagna, F.13
-
26
-
-
77953479256
-
Senescence-associated beta-galactosidase activity expression in aging hippocampal neurons
-
Geng Y.Q., Guan J.T., Xu X.H., Fu Y.C. Senescence-associated beta-galactosidase activity expression in aging hippocampal neurons. Biochem. Biophys. Res. Commun. 2010, 396:866-869.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.396
, pp. 866-869
-
-
Geng, Y.Q.1
Guan, J.T.2
Xu, X.H.3
Fu, Y.C.4
-
27
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley C.B., Futcher A.B., Greider C.W. Telomeres shorten during ageing of human fibroblasts. Nature 1990, 345:458-460.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
28
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick L., Moorhead P.S. The serial cultivation of human diploid cell strains. Exp. Cell Res. 1961, 25:585-621.
-
(1961)
Exp. Cell Res.
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
29
-
-
33644692330
-
Cellular senescence in aging primates
-
Herbig U., Ferreira M., Condel L., Carey D., Sedivy J.M. Cellular senescence in aging primates. Science 2006, 311:1257.
-
(2006)
Science
, vol.311
, pp. 1257
-
-
Herbig, U.1
Ferreira, M.2
Condel, L.3
Carey, D.4
Sedivy, J.M.5
-
30
-
-
84859352385
-
Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
-
Hewitt G., Jurk D., Marques F.D., Correia-Melo C., Hardy T., Gackowska A., Anderson R., Taschuk M., Mann J., Passos J.F. Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence. Nat. Commun. 2012, 3:708.
-
(2012)
Nat. Commun.
, vol.3
, pp. 708
-
-
Hewitt, G.1
Jurk, D.2
Marques, F.D.3
Correia-Melo, C.4
Hardy, T.5
Gackowska, A.6
Anderson, R.7
Taschuk, M.8
Mann, J.9
Passos, J.F.10
-
31
-
-
33845866857
-
Inflammation and metabolic disorders
-
Hotamisligil G.S. Inflammation and metabolic disorders. Nature 2006, 444:860-867.
-
(2006)
Nature
, vol.444
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
32
-
-
45449084795
-
Cellular senescence and organismal aging
-
Jeyapalan J.C., Sedivy J.M. Cellular senescence and organismal aging. Mech. Ageing Dev. 2008, 129:467-474.
-
(2008)
Mech. Ageing Dev.
, vol.129
, pp. 467-474
-
-
Jeyapalan, J.C.1
Sedivy, J.M.2
-
33
-
-
79952115737
-
Cellular senescence controls fibrosis in wound healing
-
Jun J.I., Lau L.F. Cellular senescence controls fibrosis in wound healing. Aging (Albany NY). 2010, 2:627-631.
-
(2010)
Aging (Albany NY).
, vol.2
, pp. 627-631
-
-
Jun, J.I.1
Lau, L.F.2
-
34
-
-
38949145803
-
A systematic look at an old problem
-
Kirkwood T.B. A systematic look at an old problem. Nature 2008, 451:644-647.
-
(2008)
Nature
, vol.451
, pp. 644-647
-
-
Kirkwood, T.B.1
-
35
-
-
79952609648
-
Age-associated increase in heterochromatic marks in murine and primate tissues
-
Kreiling J.A., Tamamori-Adachi M., Sexton A.N., Jeyapalan J.C., Munoz-Najar U., Peterson A.L., Manivannan J., Rogers E.S., Pchelintsev N.A., Adams P.D., Sedivy J.M. Age-associated increase in heterochromatic marks in murine and primate tissues. Aging Cell 2011, 10:292-304.
-
(2011)
Aging Cell
, vol.10
, pp. 292-304
-
-
Kreiling, J.A.1
Tamamori-Adachi, M.2
Sexton, A.N.3
Jeyapalan, J.C.4
Munoz-Najar, U.5
Peterson, A.L.6
Manivannan, J.7
Rogers, E.S.8
Pchelintsev, N.A.9
Adams, P.D.10
Sedivy, J.M.11
-
36
-
-
49749145668
-
Senescence of activated stellate cells limits liver fibrosis
-
Krizhanovsky V., Yon M., Dickins R.A., Hearn S., Simon J., Miething C., Yee H., Zender L., Lowe S.W. Senescence of activated stellate cells limits liver fibrosis. Cell 2008, 134:657-667.
-
(2008)
Cell
, vol.134
, pp. 657-667
-
-
Krizhanovsky, V.1
Yon, M.2
Dickins, R.A.3
Hearn, S.4
Simon, J.5
Miething, C.6
Yee, H.7
Zender, L.8
Lowe, S.W.9
-
37
-
-
66149163071
-
A comprehensive review on mesenchymal stem cell growth and senescence
-
Ksiazek K. A comprehensive review on mesenchymal stem cell growth and senescence. Rejuvenation Res. 2009, 12:105-116.
-
(2009)
Rejuvenation Res.
, vol.12
, pp. 105-116
-
-
Ksiazek, K.1
-
38
-
-
44649101304
-
Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network
-
Kuilman T., Michaloglou C., Vredeveld L.C., Douma S., van Doorn R., Desmet C.J., Aarden L.A., Mooi W.J., Peeper D.S. Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell 2008, 133:1019-1031.
-
(2008)
Cell
, vol.133
, pp. 1019-1031
-
-
Kuilman, T.1
Michaloglou, C.2
Vredeveld, L.C.3
Douma, S.4
van Doorn, R.5
Desmet, C.J.6
Aarden, L.A.7
Mooi, W.J.8
Peeper, D.S.9
-
39
-
-
78349257844
-
The essence of senescence
-
Kuilman T., Michaloglou C., Mooi W.J., Peeper D.S. The essence of senescence. Genes Dev. 2011, 24:2463-2479.
-
(2011)
Genes Dev.
, vol.24
, pp. 2463-2479
-
-
Kuilman, T.1
Michaloglou, C.2
Mooi, W.J.3
Peeper, D.S.4
-
40
-
-
80455144472
-
Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state
-
Lapasset L., Milhavet O., Prieur A., Besnard E., Babled A., Ait-Hamou N., Leschik J., Pellestor F., Ramirez J.M., De Vos J., Lehmann S., Lemaitre J.M. Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state. Genes Dev. 2011, 25:2248-2253.
-
(2011)
Genes Dev.
, vol.25
, pp. 2248-2253
-
-
Lapasset, L.1
Milhavet, O.2
Prieur, A.3
Besnard, E.4
Babled, A.5
Ait-Hamou, N.6
Leschik, J.7
Pellestor, F.8
Ramirez, J.M.9
De Vos, J.10
Lehmann, S.11
Lemaitre, J.M.12
-
41
-
-
19944432549
-
What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?
-
Leroi A.M., Bartke A., De Benedictis G., Franceschi C., Gartner A., Gonos E.S., Fedei M.E., Kivisild T., Lee S., Kartaf-Ozer N., Schumacher M., Sikora E., Slagboom E., Tatar M., Yashin A.I., Vijg J., Zwaan B. What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?. Mech. Ageing Dev. 2005, 126:421-429.
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 421-429
-
-
Leroi, A.M.1
Bartke, A.2
De Benedictis, G.3
Franceschi, C.4
Gartner, A.5
Gonos, E.S.6
Fedei, M.E.7
Kivisild, T.8
Lee, S.9
Kartaf-Ozer, N.10
Schumacher, M.11
Sikora, E.12
Slagboom, E.13
Tatar, M.14
Yashin, A.I.15
Vijg, J.16
Zwaan, B.17
-
42
-
-
79955513612
-
Manifestations and mechanisms of stem cell aging
-
Liu L., Rando T.A. Manifestations and mechanisms of stem cell aging. J. Cell Biol. 2012, 193:257-266.
-
(2012)
J. Cell Biol.
, vol.193
, pp. 257-266
-
-
Liu, L.1
Rando, T.A.2
-
43
-
-
47949096781
-
Cancer-related inflammation
-
Mantovani A., Allavena P., Sica A., Balkwill F. Cancer-related inflammation. Nature 2008, 454:436-444.
-
(2008)
Nature
, vol.454
, pp. 436-444
-
-
Mantovani, A.1
Allavena, P.2
Sica, A.3
Balkwill, F.4
-
44
-
-
80655140600
-
MTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: a roadmap from energy metabolism to stem cell renewal and aging
-
Menendez J.A., Vellon L., Oliveras-Ferraros C., Cufi S., Vazquez-Martin A. mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: a roadmap from energy metabolism to stem cell renewal and aging. Cell Cycle 2011, 10:3658-3677.
-
(2011)
Cell Cycle
, vol.10
, pp. 3658-3677
-
-
Menendez, J.A.1
Vellon, L.2
Oliveras-Ferraros, C.3
Cufi, S.4
Vazquez-Martin, A.5
-
45
-
-
78649710391
-
Role of cellular senescence in lifestyle-related disease
-
Minamino T. Role of cellular senescence in lifestyle-related disease. Circ. J. 2010, 74:2527-2533.
-
(2010)
Circ. J.
, vol.74
, pp. 2527-2533
-
-
Minamino, T.1
-
46
-
-
33846121333
-
Vascular cell senescence: contribution to atherosclerosis
-
Minamino T., Komuro I. Vascular cell senescence: contribution to atherosclerosis. Circ. Res. 2007, 100:15-26.
-
(2007)
Circ. Res.
, vol.100
, pp. 15-26
-
-
Minamino, T.1
Komuro, I.2
-
47
-
-
0033541401
-
Telomere length in fibroblasts and blood cells from healthy centenarians
-
Mondello C., Petropoulou C., Monti D., Gonos E.S., Franceschi C., Nuzzo F. Telomere length in fibroblasts and blood cells from healthy centenarians. Exp. Cell Res. 1999, 248:234-242.
-
(1999)
Exp. Cell Res.
, vol.248
, pp. 234-242
-
-
Mondello, C.1
Petropoulou, C.2
Monti, D.3
Gonos, E.S.4
Franceschi, C.5
Nuzzo, F.6
-
48
-
-
84863088886
-
Curcumin induces permanent growth arrest of human colon cancer cells: link between senescence and autophagy
-
Mosieniak G., Adamowicz M., Alster O., Jaskowiak H., Szczepankiewicz A.A., Wilczynski G.M., Ciechomska I.A., Sikora E. Curcumin induces permanent growth arrest of human colon cancer cells: link between senescence and autophagy. Mech. Ageing Dev. 2012, 133:444-455.
-
(2012)
Mech. Ageing Dev.
, vol.133
, pp. 444-455
-
-
Mosieniak, G.1
Adamowicz, M.2
Alster, O.3
Jaskowiak, H.4
Szczepankiewicz, A.A.5
Wilczynski, G.M.6
Ciechomska, I.A.7
Sikora, E.8
-
49
-
-
69949125332
-
Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence
-
Nakamura A.J., Chiang Y.J., Hathcock K.S., Horikawa I., Sedelnikova O.A., Hodes R.J., Bonner W.M. Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence. Epigenetics Chromatin. 2008, 1:6.
-
(2008)
Epigenetics Chromatin.
, vol.1
, pp. 6
-
-
Nakamura, A.J.1
Chiang, Y.J.2
Hathcock, K.S.3
Horikawa, I.4
Sedelnikova, O.A.5
Hodes, R.J.6
Bonner, W.M.7
-
50
-
-
79959637828
-
Pro-senescence therapy for cancer treatment
-
Nardella C., Clohessy J.G., Alimonti A., Pandolfi P.P. Pro-senescence therapy for cancer treatment. Nat. Rev. Cancer 2011, 11:503-511.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 503-511
-
-
Nardella, C.1
Clohessy, J.G.2
Alimonti, A.3
Pandolfi, P.P.4
-
51
-
-
84859491432
-
Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency
-
Ohmine S., Squillace K.A., Hartjes K.A., Deeds M.C., Armstrong A.S., Thatava T., Sakuma T., Terzic A., Kudva Y., Ikeda Y. Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency. Aging (Albany NY). 2012, 4:60-73.
-
(2012)
Aging (Albany NY).
, vol.4
, pp. 60-73
-
-
Ohmine, S.1
Squillace, K.A.2
Hartjes, K.A.3
Deeds, M.C.4
Armstrong, A.S.5
Thatava, T.6
Sakuma, T.7
Terzic, A.8
Kudva, Y.9
Ikeda, Y.10
-
52
-
-
84857134035
-
Telomere/telomerase system: a new target of statins pleiotropic effect?
-
Olivieri F., Mazzanti I., Abbatecola A.M., Recchioni R., Marcheselli F., Procopio A.D., Antonicelli R. Telomere/telomerase system: a new target of statins pleiotropic effect?. Curr. Vasc. Pharmacol. 2012, 10:216-224.
-
(2012)
Curr. Vasc. Pharmacol.
, vol.10
, pp. 216-224
-
-
Olivieri, F.1
Mazzanti, I.2
Abbatecola, A.M.3
Recchioni, R.4
Marcheselli, F.5
Procopio, A.D.6
Antonicelli, R.7
-
53
-
-
41549149451
-
Cellular senescence in vivo: a barrier to tumorigenesis
-
Prieur A., Peeper D.S. Cellular senescence in vivo: a barrier to tumorigenesis. Curr. Opin. Cell Biol. 2008, 20:150-155.
-
(2008)
Curr. Opin. Cell Biol.
, vol.20
, pp. 150-155
-
-
Prieur, A.1
Peeper, D.S.2
-
54
-
-
49749107218
-
Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy
-
Puig P.E., Guilly M.N., Bouchot A., Droin N., Cathelin D., Bouyer F., Favier L., Ghiringhelli F., Kroemer G., Solary E., Martin F., Chauffert B. Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy. Cell Biol. Int. 2008, 32:1031-1043.
-
(2008)
Cell Biol. Int.
, vol.32
, pp. 1031-1043
-
-
Puig, P.E.1
Guilly, M.N.2
Bouchot, A.3
Droin, N.4
Cathelin, D.5
Bouyer, F.6
Favier, L.7
Ghiringhelli, F.8
Kroemer, G.9
Solary, E.10
Martin, F.11
Chauffert, B.12
-
55
-
-
84862752615
-
Curcuminoid binding to embryonal carcinoma cells: reductive metabolism, induction of apoptosis, senescence, and inhibition of cell proliferation
-
Quitschke W.W. Curcuminoid binding to embryonal carcinoma cells: reductive metabolism, induction of apoptosis, senescence, and inhibition of cell proliferation. PLoS One 2012, 7:e39568.
-
(2012)
PLoS One
, vol.7
-
-
Quitschke, W.W.1
-
56
-
-
33845299892
-
Stem cells, senescence, neosis and self-renewal in cancer
-
Rajaraman R., Guernsey D.L., Rajaraman M.M., Rajaraman S.R. Stem cells, senescence, neosis and self-renewal in cancer. Cancer Cell Int. 2006, 6:25.
-
(2006)
Cancer Cell Int.
, vol.6
, pp. 25
-
-
Rajaraman, R.1
Guernsey, D.L.2
Rajaraman, M.M.3
Rajaraman, S.R.4
-
57
-
-
84856090875
-
Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock
-
Rando T.A., Chang H.Y. Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock. Cell 2012, 148:46-57.
-
(2012)
Cell
, vol.148
, pp. 46-57
-
-
Rando, T.A.1
Chang, H.Y.2
-
58
-
-
0038277105
-
Tumor cell senescence in cancer treatment
-
Roninson I.B. Tumor cell senescence in cancer treatment. Cancer Res. 2003, 63:2705-2715.
-
(2003)
Cancer Res.
, vol.63
, pp. 2705-2715
-
-
Roninson, I.B.1
-
59
-
-
72449147738
-
The multifunctional role of mTOR in innate immunity: implications for transplant immunity
-
Saemann M.D., Haidinger M., Hecking M., Horl W.H., Weichhart T. The multifunctional role of mTOR in innate immunity: implications for transplant immunity. Am. J. Transplant. 2009, 9:2655-2661.
-
(2009)
Am. J. Transplant.
, vol.9
, pp. 2655-2661
-
-
Saemann, M.D.1
Haidinger, M.2
Hecking, M.3
Horl, W.H.4
Weichhart, T.5
-
60
-
-
82955167885
-
Circulating leukocyte telomere length and oxidative stress: a new target for statin therapy
-
Saliques S., Teyssier J.R., Vergely C., Lorgis L., Lorin J., Farnier M., Donzel A., Sicard P., Berchoud J., Lagrost A.C., Touzery C., Ragot S., Cottin Y., Rochette L., Zeller M. Circulating leukocyte telomere length and oxidative stress: a new target for statin therapy. Atherosclerosis 2011, 219:753-760.
-
(2011)
Atherosclerosis
, vol.219
, pp. 753-760
-
-
Saliques, S.1
Teyssier, J.R.2
Vergely, C.3
Lorgis, L.4
Lorin, J.5
Farnier, M.6
Donzel, A.7
Sicard, P.8
Berchoud, J.9
Lagrost, A.C.10
Touzery, C.11
Ragot, S.12
Cottin, Y.13
Rochette, L.14
Zeller, M.15
-
61
-
-
52449083947
-
Curcumin in cell death processes: a challenge for CAM of age-related pathologies
-
Salvioli S., Sikora E., Cooper E.L., Franceschi C. Curcumin in cell death processes: a challenge for CAM of age-related pathologies. Evid Based Complement Alternat Med. 2007, 4:181-190.
-
(2007)
Evid Based Complement Alternat Med.
, vol.4
, pp. 181-190
-
-
Salvioli, S.1
Sikora, E.2
Cooper, E.L.3
Franceschi, C.4
-
62
-
-
1642602686
-
Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks
-
Sedelnikova O.A., Horikawa I., Zimonjic D.B., Popescu N.C., Bonner W.M., Barrett J.C. Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks. Nat. Cell Biol. 2004, 6:168-170.
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 168-170
-
-
Sedelnikova, O.A.1
Horikawa, I.2
Zimonjic, D.B.3
Popescu, N.C.4
Bonner, W.M.5
Barrett, J.C.6
-
63
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano M., Lin A.W., McCurrach M.E., Beach D., Lowe S.W. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997, 88:593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
64
-
-
77249109022
-
The promise of slow down ageing may come from curcumin
-
Sikora E., Bielak-Zmijewska A., Mosieniak G., Piwocka K. The promise of slow down ageing may come from curcumin. Curr. Pharm. Des. 2010, 16:884-892.
-
(2010)
Curr. Pharm. Des.
, vol.16
, pp. 884-892
-
-
Sikora, E.1
Bielak-Zmijewska, A.2
Mosieniak, G.3
Piwocka, K.4
-
65
-
-
78650243948
-
Impact of cellular senescence signature on ageing research
-
Sikora E., Arendt T., Bennett M., Narita M. Impact of cellular senescence signature on ageing research. Ageing Res. Rev. 2011, 10:146-152.
-
(2011)
Ageing Res. Rev.
, vol.10
, pp. 146-152
-
-
Sikora, E.1
Arendt, T.2
Bennett, M.3
Narita, M.4
-
66
-
-
58149327460
-
Induction of senescence with doxorubicin leads to increased genomic instability of HCT116 cells
-
Sliwinska M.A., Mosieniak G., Wolanin K., Babik A., Piwocka K., Magalska A., Szczepanowska J., Fronk J., Sikora E. Induction of senescence with doxorubicin leads to increased genomic instability of HCT116 cells. Mech. Ageing Dev. 2009, 130:24-32.
-
(2009)
Mech. Ageing Dev.
, vol.130
, pp. 24-32
-
-
Sliwinska, M.A.1
Mosieniak, G.2
Wolanin, K.3
Babik, A.4
Piwocka, K.5
Magalska, A.6
Szczepanowska, J.7
Fronk, J.8
Sikora, E.9
-
67
-
-
0037687519
-
Human epithelial cell immortalization as a step in carcinogenesis
-
Stampfer M.R., Yaswen P. Human epithelial cell immortalization as a step in carcinogenesis. Cancer Lett. 2003, 194:199-208.
-
(2003)
Cancer Lett.
, vol.194
, pp. 199-208
-
-
Stampfer, M.R.1
Yaswen, P.2
-
68
-
-
0026322601
-
Senescent cells fail to express cdc2, cycA, and cycB in response to mitogen stimulation
-
Stein G.H., Drullinger L.F., Robetorye R.S., Pereira-Smith O.M., Smith J.R. Senescent cells fail to express cdc2, cycA, and cycB in response to mitogen stimulation. Proc. Natl. Acad. Sci. U. S. A. 1991, 88:11012-11016.
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 11012-11016
-
-
Stein, G.H.1
Drullinger, L.F.2
Robetorye, R.S.3
Pereira-Smith, O.M.4
Smith, J.R.5
-
69
-
-
84863660563
-
Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice
-
Mar 26. [Electronic publication ahead of print]
-
Strong R., Miller R.A., Astle C.M., Baur J.A., de Cabo R., Fernandez E., Guo W., Javors M., Kirkland J.L., Nelson J.F., Sinclair D.A., Teter B., Williams D., Zaveri N., Nadon N.L., Harrison D.E. Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice. J. Gerontol. A. Biol. Sci. Med. Sci. 2012, Mar 26. [Electronic publication ahead of print].
-
(2012)
J. Gerontol. A. Biol. Sci. Med. Sci.
-
-
Strong, R.1
Miller, R.A.2
Astle, C.M.3
Baur, J.A.4
de Cabo, R.5
Fernandez, E.6
Guo, W.7
Javors, M.8
Kirkland, J.L.9
Nelson, J.F.10
Sinclair, D.A.11
Teter, B.12
Williams, D.13
Zaveri, N.14
Nadon, N.L.15
Harrison, D.E.16
-
70
-
-
84859492402
-
Molecular links between cellular senescence, longevity and age-related diseases-a systems biology perspective
-
Tacutu R., Budovsky A., Yanai H., Fraifeld V.E. Molecular links between cellular senescence, longevity and age-related diseases-a systems biology perspective. Aging (Albany NY). 2011, 3:1178-1191.
-
(2011)
Aging (Albany NY).
, vol.3
, pp. 1178-1191
-
-
Tacutu, R.1
Budovsky, A.2
Yanai, H.3
Fraifeld, V.E.4
-
71
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
72
-
-
77954687175
-
Changes of telomere length with aging
-
Takubo K., Aida J., Izumiyama-Shimomura N., Ishikawa N., Sawabe M., Kurabayashi R., Shiraishi H., Arai T., Nakamura K.-N. Changes of telomere length with aging. Geriatr. Gerontol. Int. 2010, 10(Suppl. 1):S197-S206.
-
(2010)
Geriatr. Gerontol. Int.
, vol.10
, Issue.SUPPL. 1
-
-
Takubo, K.1
Aida, J.2
Izumiyama-Shimomura, N.3
Ishikawa, N.4
Sawabe, M.5
Kurabayashi, R.6
Shiraishi, H.7
Arai, T.8
Nakamura, K.-N.9
-
73
-
-
78349299099
-
Fat tissue, aging, and cellular senescence
-
Tchkonia T., Morbeck D.E., Von Zglinicki T., Van Deursen J., Lustgarten J., Scrable H., Khosla S., Jensen M.D., Kirkland J.L. Fat tissue, aging, and cellular senescence. Aging Cell 2010, 9:667-684.
-
(2010)
Aging Cell
, vol.9
, pp. 667-684
-
-
Tchkonia, T.1
Morbeck, D.E.2
Von Zglinicki, T.3
Van Deursen, J.4
Lustgarten, J.5
Scrable, H.6
Khosla, S.7
Jensen, M.D.8
Kirkland, J.L.9
-
74
-
-
80053373582
-
Statin-induced myopathies
-
Tomaszewski M., Stepien K.M., Tomaszewska J., Czuczwar S.J. Statin-induced myopathies. Pharmacol. Rep. 2011, 63:859-866.
-
(2011)
Pharmacol. Rep.
, vol.63
, pp. 859-866
-
-
Tomaszewski, M.1
Stepien, K.M.2
Tomaszewska, J.3
Czuczwar, S.J.4
-
75
-
-
84859314596
-
Signalling the end of the line
-
van Tuyn J., Adams P.D. Signalling the end of the line. Nat. Cell Biol. 2012, 14:339-341.
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 339-341
-
-
van Tuyn, J.1
Adams, P.D.2
-
76
-
-
84975806501
-
Inflammatory networks in ageing, age-related diseases and longevity
-
Vasto S., Candore G., Balistreri C.R., Caruso M., Colonna-Romano G., Grimaldi M.P., Listi F., Nuzzo D., Lio D., Caruso C. Inflammatory networks in ageing, age-related diseases and longevity. Mech. Ageing Dev. 2007, 128:83-91.
-
(2007)
Mech. Ageing Dev.
, vol.128
, pp. 83-91
-
-
Vasto, S.1
Candore, G.2
Balistreri, C.R.3
Caruso, M.4
Colonna-Romano, G.5
Grimaldi, M.P.6
Listi, F.7
Nuzzo, D.8
Lio, D.9
Caruso, C.10
-
77
-
-
0037335554
-
Telomere-driven replicative senescence is a stress response
-
von Zglinicki T., Petrie J., Kirkwood T.B. Telomere-driven replicative senescence is a stress response. Nat. Biotechnol. 2003, 21:229-230.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 229-230
-
-
von Zglinicki, T.1
Petrie, J.2
Kirkwood, T.B.3
-
78
-
-
0034894667
-
Replicative senescence of human endothelial cells in vitro involves G1 arrest, polyploidization and senescence-associated apoptosis
-
Wagner M., Hampel B., Bernhard D., Hala M., Zwerschke W., Jansen-Durr P. Replicative senescence of human endothelial cells in vitro involves G1 arrest, polyploidization and senescence-associated apoptosis. Exp. Gerontol. 2001, 36:1327-1347.
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 1327-1347
-
-
Wagner, M.1
Hampel, B.2
Bernhard, D.3
Hala, M.4
Zwerschke, W.5
Jansen-Durr, P.6
-
79
-
-
66149167336
-
DNA damage response and cellular senescence in tissues of aging mice
-
Wang C., Jurk D., Maddick M., Nelson G., Martin-Ruiz C., von Zglinicki T. DNA damage response and cellular senescence in tissues of aging mice. Aging Cell 2009, 8:311-323.
-
(2009)
Aging Cell
, vol.8
, pp. 311-323
-
-
Wang, C.1
Jurk, D.2
Maddick, M.3
Nelson, G.4
Martin-Ruiz, C.5
von Zglinicki, T.6
-
80
-
-
33846937033
-
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
-
Xue W., Zender L., Miething C., Dickins R.A., Hernando E., Krizhanovsky V., Cordon-Cardo C., Lowe S.W. Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 2007, 445:656-660.
-
(2007)
Nature
, vol.445
, pp. 656-660
-
-
Xue, W.1
Zender, L.2
Miething, C.3
Dickins, R.A.4
Hernando, E.5
Krizhanovsky, V.6
Cordon-Cardo, C.7
Lowe, S.W.8
|