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Volumn 17, Issue , 2015, Pages 317-349

Biomaterial Strategies for Immunomodulation

Author keywords

Immunoengineering; Immunotherapy; Vaccination

Indexed keywords

BIOMATERIALS; DISEASES; IMMUNE SYSTEM; MEDICAL APPLICATIONS; VACCINES;

EID: 84946233311     PISSN: 15239829     EISSN: 15454274     Source Type: Book Series    
DOI: 10.1146/annurev-bioeng-071813-104814     Document Type: Review
Times cited : (142)

References (199)
  • 2
    • 76249096897 scopus 로고    scopus 로고
    • A self-Assembling peptide acting as an immune adjuvant
    • Rudra JS, Tian YF, Jung JP, Collier JH. 2010. A self-Assembling peptide acting as an immune adjuvant. PNAS 107:622-27
    • (2010) PNAS , vol.107 , pp. 622-627
    • Rudra, J.S.1    Tian, Y.F.2    Jung, J.P.3    Collier, J.H.4
  • 4
    • 84863568613 scopus 로고    scopus 로고
    • Self-Assembled peptide nanofibers raising durable antibody responses against a malaria epitope
    • Rudra JS, Mishra S, Chong AS, Mitchell RA, Nardin EH, et al. 2012. Self-Assembled peptide nanofibers raising durable antibody responses against a malaria epitope. Biomaterials 33:6476-84
    • (2012) Biomaterials , vol.33 , pp. 6476-6484
    • Rudra, J.S.1    Mishra, S.2    Chong, A.S.3    Mitchell, R.A.4    Nardin, E.H.5
  • 5
    • 84882924297 scopus 로고    scopus 로고
    • The use of self-Adjuvanting nanofiber vaccines to elicit high-Affinity B cell responses to peptide antigens without inflammation
    • Chen J, Pompano RR, Santiago FW, Maillat L, Sciammas R, et al. 2013. The use of self-Adjuvanting nanofiber vaccines to elicit high-Affinity B cell responses to peptide antigens without inflammation. Biomaterials 34:8776-85
    • (2013) Biomaterials , vol.34 , pp. 8776-8785
    • Chen, J.1    Pompano, R.R.2    Santiago, F.W.3    Maillat, L.4    Sciammas, R.5
  • 7
    • 79952517440 scopus 로고    scopus 로고
    • Multifactorial optimization of endothelial cell growth using modular synthetic extracellular matrices
    • Jung JP, Moyano JV, Collier JH. 2011. Multifactorial optimization of endothelial cell growth using modular synthetic extracellular matrices. Integr. Biol. 3:185-96
    • (2011) Integr. Biol. , vol.3 , pp. 185-196
    • Jung, J.P.1    Moyano, J.V.2    Collier, J.H.3
  • 8
    • 60849130956 scopus 로고    scopus 로고
    • Peptide nanoparticles serve as a powerful platform for the immunogenic display of poorly antigenic actin determinants
    • Schroeder U, Graff A, Buchmeier S, Rigler P, Silvan U, et al. 2009. Peptide nanoparticles serve as a powerful platform for the immunogenic display of poorly antigenic actin determinants. J. Mol. Biol. 386:1368-81
    • (2009) J. Mol. Biol. , vol.386 , pp. 1368-1381
    • Schroeder, U.1    Graff, A.2    Buchmeier, S.3    Rigler, P.4    Silvan, U.5
  • 9
    • 84895071915 scopus 로고    scopus 로고
    • Nanoclusters self-Assembled from conformation-stabilized influenzaM2e as broadly cross-protective influenza vaccines
    • Wang L, Hess A, Chang TZ, Wang Y-C, Champion JA, et al. 2014. Nanoclusters self-Assembled from conformation-stabilized influenzaM2e as broadly cross-protective influenza vaccines. Nanomedicine 10:473-82
    • (2014) Nanomedicine , vol.10 , pp. 473-482
    • Wang, L.1    Hess, A.2    Chang, T.Z.3    Wang, Y.-C.4    Champion, J.A.5
  • 10
    • 84865459821 scopus 로고    scopus 로고
    • Differential functional effects of biomaterials on dendritic cell maturation
    • Park J, Babensee JE. 2012. Differential functional effects of biomaterials on dendritic cell maturation. Acta Biomater. 8:3606-17
    • (2012) Acta Biomater. , vol.8 , pp. 3606-3617
    • Park, J.1    Babensee, J.E.2
  • 11
    • 84912561549 scopus 로고    scopus 로고
    • Phenotype and polarization of autologous t cells by biomaterialtreated dendritic cells
    • Park J, Gerber MH, Babensee JE. 2014. Phenotype and polarization of autologous t cells by biomaterialtreated dendritic cells. J. Biomed. Mater. Res. A 103:170-84
    • (2014) J. Biomed. Mater. Res. A , vol.103 , pp. 170-184
    • Park, J.1    Gerber, M.H.2    Babensee, J.E.3
  • 12
    • 24044543562 scopus 로고    scopus 로고
    • Differential levels of dendritic cell maturation on different biomaterials used in combination products
    • Babensee JE, Paranjpe A. 2005. Differential levels of dendritic cell maturation on different biomaterials used in combination products. J. Biomed. Mater. Res. A 74:503-10
    • (2005) J. Biomed. Mater. Res. A , vol.74 , pp. 503-510
    • Babensee, J.E.1    Paranjpe, A.2
  • 13
    • 29444441343 scopus 로고    scopus 로고
    • Manifold mechanisms of toll-like receptor-ligand recognition
    • Ishii KJ, Coban C, Akira S. 2005. Manifold mechanisms of toll-like receptor-ligand recognition. J. Clin. Immunol. 25:511-21
    • (2005) J. Clin. Immunol. , vol.25 , pp. 511-521
    • Ishii, K.J.1    Coban, C.2    Akira, S.3
  • 14
    • 5644244327 scopus 로고    scopus 로고
    • Approach to the comprehensive analysis of glycoproteins isolated from human serum using a multi-lectin affinity column
    • Yang Z, Hancock WS. 2004. Approach to the comprehensive analysis of glycoproteins isolated from human serum using a multi-lectin affinity column. J. Chromatogr. A 1053:79-88
    • (2004) J. Chromatogr. A , vol.1053 , pp. 79-88
    • Yang, Z.1    Hancock, W.S.2
  • 15
    • 33750728433 scopus 로고    scopus 로고
    • Targeting dendritic cells with biomaterials: Developing the next generation of vaccines
    • Reddy ST, Swartz MA, Hubbell JA. 2006. Targeting dendritic cells with biomaterials: developing the next generation of vaccines. Trends Immunol. 27:573-79
    • (2006) Trends Immunol. , vol.27 , pp. 573-579
    • Reddy, S.T.1    Swartz, M.A.2    Hubbell, J.A.3
  • 16
    • 77953081609 scopus 로고    scopus 로고
    • The role of multiple toll-like receptor signalling cascades on interactions between biomedical polymers and dendritic cells
    • Shokouhi B, Coban C, Hasirci V, Aydin E, Dhanasingh A, et al. 2010. The role of multiple toll-like receptor signalling cascades on interactions between biomedical polymers and dendritic cells. Biomaterials 31:5759-71
    • (2010) Biomaterials , vol.31 , pp. 5759-5771
    • Shokouhi, B.1    Coban, C.2    Hasirci, V.3    Aydin, E.4    Dhanasingh, A.5
  • 17
    • 78649760576 scopus 로고    scopus 로고
    • The role of integrins in the recognition and response of dendritic cells to biomaterials
    • Rogers TH, Babensee JE. 2011. The role of integrins in the recognition and response of dendritic cells to biomaterials. Biomaterials 32:1270-79
    • (2011) Biomaterials , vol.32 , pp. 1270-1279
    • Rogers, T.H.1    Babensee, J.E.2
  • 19
    • 0142258106 scopus 로고    scopus 로고
    • Humoral immune responses to model antigen co-delivered with biomaterials used in tissue engineering
    • Matzelle MM, Babensee JE. 2004. Humoral immune responses to model antigen co-delivered with biomaterials used in tissue engineering. Biomaterials 25:295-304
    • (2004) Biomaterials , vol.25 , pp. 295-304
    • Matzelle, M.M.1    Babensee, J.E.2
  • 20
    • 10644221275 scopus 로고    scopus 로고
    • The effect of the physical form of poly(lactic-co-glycolic acid) carriers on the humoral immune response to co-delivered antigen
    • Bennewitz NL, Babensee JE. 2005. The effect of the physical form of poly(lactic-co-glycolic acid) carriers on the humoral immune response to co-delivered antigen. Biomaterials 26:2991-99
    • (2005) Biomaterials , vol.26 , pp. 2991-2999
    • Bennewitz, N.L.1    Babensee, J.E.2
  • 21
    • 40649091858 scopus 로고    scopus 로고
    • Interaction of dendritic cells with biomaterials
    • Babensee JE. 2008. Interaction of dendritic cells with biomaterials. Semin. Immunol. 20:101-8
    • (2008) Semin. Immunol. , vol.20 , pp. 101-108
    • Babensee, J.E.1
  • 22
    • 77956271261 scopus 로고    scopus 로고
    • Biomaterial adjuvant effect is attenuated by anti-inflammatory drug delivery or material selection
    • Norton LW, Park J, Babensee JE. 2010. Biomaterial adjuvant effect is attenuated by anti-inflammatory drug delivery or material selection. J. Control. Release 146:341-48
    • (2010) J. Control. Release , vol.146 , pp. 341-348
    • Norton, L.W.1    Park, J.2    Babensee, J.E.3
  • 23
    • 81355147743 scopus 로고    scopus 로고
    • Adaptive micro and nanoparticles: Temporal control over carrier properties to facilitate drug delivery
    • Yoo J-W, Doshi N, Mitragotri S. 2011. Adaptive micro and nanoparticles: temporal control over carrier properties to facilitate drug delivery. Adv. Drug Deliv. Rev. 63:1247-56
    • (2011) Adv. Drug Deliv. Rev. , vol.63 , pp. 1247-1256
    • Yoo, J.-W.1    Doshi, N.2    Mitragotri, S.3
  • 24
    • 0034996764 scopus 로고    scopus 로고
    • Long-circulating and target-specific nanoparticles: Theory to practice
    • Moghimi SM, Hunter AC,Murray JC. 2001. Long-circulating and target-specific nanoparticles: theory to practice. Pharmacol. Rev. 53:283-318
    • (2001) Pharmacol. Rev. , vol.53 , pp. 283-318
    • Moghimi, S.M.1    Hunter, A.C.2    Murray, J.C.3
  • 25
    • 84861578472 scopus 로고    scopus 로고
    • Control of size dispersity of chitosan biopolymer microparticles and nanoparticles to influence vaccine trafficking and cell uptake
    • Kobiasi MA, Chua BY, Tonkin D, Jackson DC, Mainwaring DE. 2012. Control of size dispersity of chitosan biopolymer microparticles and nanoparticles to influence vaccine trafficking and cell uptake. J. Biomed. Mater. Res. A 100:1859-67
    • (2012) J. Biomed. Mater. Res. A , vol.100 , pp. 1859-1867
    • Kobiasi, M.A.1    Chua, B.Y.2    Tonkin, D.3    Jackson, D.C.4    Mainwaring, D.E.5
  • 26
    • 0348014781 scopus 로고    scopus 로고
    • Morphological characteristics of total joint arthroplasty-derived ultra-high molecular weight polyethylene (UHMWPE) wear debris that provoke inflammation in a murine model of inflammation
    • Sieving A, Wu B, Mayton L, Nasser S, Wooley PH. 2003. Morphological characteristics of total joint arthroplasty-derived ultra-high molecular weight polyethylene (UHMWPE) wear debris that provoke inflammation in a murine model of inflammation. J. Biomed. Mater. Res. A 64:457-64
    • (2003) J. Biomed. Mater. Res. A , vol.64 , pp. 457-464
    • Sieving, A.1    Wu, B.2    Mayton, L.3    Nasser, S.4    Wooley, P.H.5
  • 27
    • 57749207052 scopus 로고    scopus 로고
    • Intravascular delivery of particulate systems: Does geometry really matter
    • Decuzzi P, Pasqualini R, Arap W, Ferrari M. 2009. Intravascular delivery of particulate systems: does geometry really matter? Pharm. Res. 26:235-43
    • (2009) Pharm. Res. , vol.26 , pp. 235-243
    • Decuzzi, P.1    Pasqualini, R.2    Arap, W.3    Ferrari, M.4
  • 28
    • 17144417434 scopus 로고    scopus 로고
    • A theoretical model for the margination of particles within blood vessels
    • Decuzzi P, Lee S, Bhushan B, Ferrari M. 2005. A theoretical model for the margination of particles within blood vessels. Ann. Biomed. Eng. 33:179-90
    • (2005) Ann. Biomed. Eng. , vol.33 , pp. 179-190
    • Decuzzi, P.1    Lee, S.2    Bhushan, B.3    Ferrari, M.4
  • 29
    • 0015884996 scopus 로고
    • The role of blood flow in platelet adhesion, fibrin deposition, and formation of mural thrombi
    • Baumgartner HR. 1973. The role of blood flow in platelet adhesion, fibrin deposition, and formation of mural thrombi. Microvasc. Res. 5:167-79
    • (1973) Microvasc. Res. , vol.5 , pp. 167-179
    • Baumgartner, H.R.1
  • 30
    • 77955607302 scopus 로고    scopus 로고
    • Factors that control the circulation time of nanoparticles in blood: Challenges, solutions and future prospects
    • Yoo J-W, Chambers E, Mitragotri S. 2010. Factors that control the circulation time of nanoparticles in blood: challenges, solutions and future prospects. Curr. Pharm. Des. 16:2298-307
    • (2010) Curr. Pharm. Des. , vol.16 , pp. 2298-2307
    • Yoo, J.-W.1    Chambers, E.2    Mitragotri, S.3
  • 31
    • 0019991617 scopus 로고
    • Blood clearance and organ deposition of intravenously administered colloidal particles: The effects of particle size, nature and shape
    • Ilium L, Davis SS, Wilson CG, Thomas NW, Frier M, Hardy JG. 1982. Blood clearance and organ deposition of intravenously administered colloidal particles: the effects of particle size, nature and shape. Int. J. Pharm. 12:135-46
    • (1982) Int. J. Pharm. , vol.12 , pp. 135-146
    • Ilium, L.1    Davis, S.S.2    Wilson, C.G.3    Thomas, N.W.4    Frier, M.5    Hardy, J.G.6
  • 32
    • 34547178393 scopus 로고    scopus 로고
    • Particle shape: A new design parameter for micro-And nanoscale drug delivery carriers
    • Champion JA, Katare YK, Mitragotri S. 2007. Particle shape: A new design parameter for micro-And nanoscale drug delivery carriers. J. Control. Release 121:3-9
    • (2007) J. Control. Release , vol.121 , pp. 3-9
    • Champion, J.A.1    Katare, Y.K.2    Mitragotri, S.3
  • 33
    • 77955175216 scopus 로고    scopus 로고
    • Strategies in the design of nanoparticles for therapeutic applications
    • Petros RA, DeSimone JM. 2010. Strategies in the design of nanoparticles for therapeutic applications. Nat. Rev. Drug Discov. 9:615-27
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 615-627
    • Petros, R.A.1    DeSimone, J.M.2
  • 34
    • 57749178400 scopus 로고    scopus 로고
    • Shape induced inhibition of phagocytosis of polymer particles
    • Champion JA, Mitragotri S. 2009. Shape induced inhibition of phagocytosis of polymer particles. Pharm. Res. 26:244-49
    • (2009) Pharm. Res. , vol.26 , pp. 244-249
    • Champion, J.A.1    Mitragotri, S.2
  • 35
    • 0035249938 scopus 로고    scopus 로고
    • Self-Assembly of monodispersed spherical colloids into complex aggregates with well-defined sizes, shapes, and structures
    • Yin Y, Xia Y. 2001. Self-Assembly of monodispersed spherical colloids into complex aggregates with well-defined sizes, shapes, and structures. Adv. Mater. 13:267-71
    • (2001) Adv. Mater. , vol.13 , pp. 267-271
    • Yin, Y.1    Xia, Y.2
  • 36
    • 48349116380 scopus 로고    scopus 로고
    • Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers
    • Muro S, Garnacho C, Champion JA, Leferovich J, Gajewski C, et al. 2008. Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers. Mol. Ther. 16:1450-58
    • (2008) Mol. Ther. , vol.16 , pp. 1450-1458
    • Muro, S.1    Garnacho, C.2    Champion, J.A.3    Leferovich, J.4    Gajewski, C.5
  • 37
    • 74349124409 scopus 로고    scopus 로고
    • Endocytosis and intracellular distribution of PLGA particles in endothelial cells: Effect of particle geometry
    • Yoo J-W, Doshi N, Mitragotri S. 2010. Endocytosis and intracellular distribution of PLGA particles in endothelial cells: effect of particle geometry. Macromol. Rapid Commun. 31:142-48
    • (2010) Macromol. Rapid Commun. , vol.31 , pp. 142-148
    • Yoo, J.-W.1    Doshi, N.2    Mitragotri, S.3
  • 38
    • 52249093974 scopus 로고    scopus 로고
    • Shape effects of nanoparticles conjugated with cell-penetrating peptides (HIV Tat PTD) on CHO cell uptake
    • Zhang K, Fang H, Chen Z, Taylor J-SA, Wooley KL. 2008. Shape effects of nanoparticles conjugated with cell-penetrating peptides (HIV Tat PTD) on CHO cell uptake. Bioconjug. Chem. 19:1880-87
    • (2008) Bioconjug. Chem. , vol.19 , pp. 1880-1887
    • Zhang, K.1    Fang, H.2    Chen, Z.3    Taylor, J.-S.A.4    Wooley, K.L.5
  • 40
    • 84875421244 scopus 로고    scopus 로고
    • Tuning innate immune activation by surface texturing of polymer microparticles: The role of shape in inflammasome activation
    • Vaine CA, Patel MK, Zhu J, Lee E, Finberg RW, et al. 2013. Tuning innate immune activation by surface texturing of polymer microparticles: the role of shape in inflammasome activation. J. Immunol. 190:3525-32
    • (2013) J. Immunol. , vol.190 , pp. 3525-3532
    • Vaine, C.A.1    Patel, M.K.2    Zhu, J.3    Lee, E.4    Finberg, R.W.5
  • 41
    • 0016612425 scopus 로고
    • The effect of particle size and charge on the clearance rates of liposomes and liposome encapsulated drugs
    • Juliano RL, Stamp D. 1975. The effect of particle size and charge on the clearance rates of liposomes and liposome encapsulated drugs. Biochem. Biophys. Res. Commun. 63:651-58
    • (1975) Biochem. Biophys. Res. Commun. , vol.63 , pp. 651-658
    • Juliano, R.L.1    Stamp, D.2
  • 42
    • 84878030500 scopus 로고    scopus 로고
    • Physicochemical characteristics of nanoparticles affect circulation, biodistribution, cellular internalization, and trafficking
    • Duan X, Li Y. 2013. Physicochemical characteristics of nanoparticles affect circulation, biodistribution, cellular internalization, and trafficking. Small 9:1521-32
    • (2013) Small , vol.9 , pp. 1521-1532
    • Duan, X.1    Li, Y.2
  • 43
    • 33646384586 scopus 로고    scopus 로고
    • Parameters influencing the stealthiness of colloidal drug delivery systems
    • Vonarbourg A, Passirani C, Saulnier P, Benoit J-P. 2006. Parameters influencing the stealthiness of colloidal drug delivery systems. Biomaterials 27:4356-73
    • (2006) Biomaterials , vol.27 , pp. 4356-4373
    • Vonarbourg, A.1    Passirani, C.2    Saulnier, P.3    Benoit, J.-P.4
  • 44
    • 46749119051 scopus 로고    scopus 로고
    • Role of particle size in phagocytosis of polymeric microspheres
    • Champion JA, Walker A, Mitragotri S. 2008. Role of particle size in phagocytosis of polymeric microspheres. Pharm. Res. 25:1815-21
    • (2008) Pharm. Res. , vol.25 , pp. 1815-1821
    • Champion, J.A.1    Walker, A.2    Mitragotri, S.3
  • 45
    • 51049090204 scopus 로고    scopus 로고
    • Nanoparticle therapeutics: An emerging treatment modality for cancer
    • Davis ME, Chen ZG, Shin DM. 2008. Nanoparticle therapeutics: An emerging treatment modality for cancer. Nat. Rev. Drug Discov. 7:771-82
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 771-782
    • Davis, M.E.1    Chen, Z.G.2    Shin, D.M.3
  • 46
    • 51049092308 scopus 로고    scopus 로고
    • Factors affecting the clearance and biodistribution of polymeric nanoparticles
    • Alexis F, PridgenE,MolnarLK, Farokhzad OC. 2008. Factors affecting the clearance and biodistribution of polymeric nanoparticles. Mol. Pharm. 5:505-15
    • (2008) Mol. Pharm. , vol.5 , pp. 505-515
    • Alexis, F.1    Pridgen, E.2    Molnar, L.K.3    Farokhzad, O.C.4
  • 47
    • 15044362503 scopus 로고    scopus 로고
    • Ficoll and dextran vs. Globular proteins as probes for testing glomerular permselectivity: Effects of molecular size, shape, charge, and deformability
    • Venturoli D, Rippe B. 2005. Ficoll and dextran vs. globular proteins as probes for testing glomerular permselectivity: effects of molecular size, shape, charge, and deformability. Am. J. Physiol. Ren. Physiol. 288:F605-13
    • (2005) Am. J. Physiol. Ren. Physiol. , vol.288 , pp. F605-F613
    • Venturoli, D.1    Rippe, B.2
  • 48
    • 0031903379 scopus 로고    scopus 로고
    • Transvascular drug delivery in solid tumors
    • Yuan F. 1998. Transvascular drug delivery in solid tumors. Semin. Radiat. Oncol. 8:164-75
    • (1998) Semin. Radiat. Oncol. , vol.8 , pp. 164-175
    • Yuan, F.1
  • 49
    • 21344448185 scopus 로고    scopus 로고
    • Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model
    • Foged C, Brodin B, Frokjaer S, Sundblad A. 2005. Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model. Int. J. Pharm. 298:315-22
    • (2005) Int. J. Pharm. , vol.298 , pp. 315-322
    • Foged, C.1    Brodin, B.2    Frokjaer, S.3    Sundblad, A.4
  • 50
    • 58149182691 scopus 로고    scopus 로고
    • The role of phagosomal pH on the size-dependent efficiency of crosspresentation by dendritic cells
    • Tran KK, Shen H. 2009. The role of phagosomal pH on the size-dependent efficiency of crosspresentation by dendritic cells. Biomaterials 30:1356-62
    • (2009) Biomaterials , vol.30 , pp. 1356-1362
    • Tran, K.K.1    Shen, H.2
  • 51
    • 84899938460 scopus 로고    scopus 로고
    • Molecular factors in dendritic cell responses to adsorbed glycoconjugates
    • Hotaling NA, Cummings RD, Ratner DM, Babensee JE. 2014. Molecular factors in dendritic cell responses to adsorbed glycoconjugates. Biomaterials 35:5862-74
    • (2014) Biomaterials , vol.35 , pp. 5862-5874
    • Hotaling, N.A.1    Cummings, R.D.2    Ratner, D.M.3    Babensee, J.E.4
  • 52
    • 80052699275 scopus 로고    scopus 로고
    • Modulating pharmacokinetics, tumor uptake and biodistribution by engineered nanoparticles
    • Arvizo RR, Miranda OR, Moyano DF,Walden CA, Giri K, et al. 2011. Modulating pharmacokinetics, tumor uptake and biodistribution by engineered nanoparticles. PLOS ONE 6:e24374
    • (2011) PLOS ONE , vol.6 , pp. e24374
    • Arvizo, R.R.1    Miranda, O.R.2    Moyano, D.F.3    Walden, C.A.4    Giri, K.5
  • 53
    • 77249104877 scopus 로고    scopus 로고
    • Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles
    • He C, Hu Y, Yin L, Tang C, Yin C. 2010. Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles. Biomaterials 31:3657-66
    • (2010) Biomaterials , vol.31 , pp. 3657-3666
    • He, C.1    Hu, Y.2    Yin, L.3    Tang, C.4    Yin, C.5
  • 54
    • 0032214525 scopus 로고    scopus 로고
    • Surface-modified biodegradable albumin nano-And microspheres. II: Effect of surface charges on in vitro phagocytosis and biodistribution in rats
    • Roser M, Fischer D, Kissel T. 1998. Surface-modified biodegradable albumin nano-And microspheres. II: Effect of surface charges on in vitro phagocytosis and biodistribution in rats. Eur. J. Pharm. Biopharm. 46:255-63
    • (1998) Eur. J. Pharm. Biopharm. , vol.46 , pp. 255-263
    • Roser, M.1    Fischer, D.2    Kissel, T.3
  • 55
    • 0035845725 scopus 로고    scopus 로고
    • Evaluation of particle uptake in human blood monocyte-derived cells in vitro. Does phagocytosis activity of dendritic cells measure up with macrophages
    • Thiele L, Rothen-Rutishauser B, Jilek S,Wunderli-Allenspach H, Merkle HP,Walter E. 2001. Evaluation of particle uptake in human blood monocyte-derived cells in vitro. Does phagocytosis activity of dendritic cells measure up with macrophages? J. Control. Release 76:59-71
    • (2001) J. Control. Release , vol.76 , pp. 59-71
    • Thiele, L.1    Rothen-Rutishauser, B.2    Jilek, S.3    Wunderli-Allenspach, H.4    Merkle, H.P.5    Walter, E.6
  • 56
    • 67649637644 scopus 로고    scopus 로고
    • Long-circulation of hemoglobin-loaded polymeric nanoparticles as oxygen carriers with modulated surface charges
    • Xu F, Yuan Y, Shan X, Liu C, Tao X, et al. 2009. Long-circulation of hemoglobin-loaded polymeric nanoparticles as oxygen carriers with modulated surface charges. Int. J. Pharm. 377:199-206
    • (2009) Int. J. Pharm. , vol.377 , pp. 199-206
    • Xu, F.1    Yuan, Y.2    Shan, X.3    Liu, C.4    Tao, X.5
  • 57
    • 79952008706 scopus 로고    scopus 로고
    • The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles
    • Xiao K, Li Y, Luo J, Lee JS, Xiao W, et al. 2011. The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles. Biomaterials 32:3435-46
    • (2011) Biomaterials , vol.32 , pp. 3435-3446
    • Xiao, K.1    Li, Y.2    Luo, J.3    Lee, J.S.4    Xiao, W.5
  • 58
    • 30144441248 scopus 로고    scopus 로고
    • Preparation of fluorescent carboxyl and amino functionalized polystyrene particles by miniemulsion polymerization as markers for cells
    • Holzapfel V,Musyanovych A, Landfester K, LorenzMR, Mailänder V. 2005. Preparation of fluorescent carboxyl and amino functionalized polystyrene particles by miniemulsion polymerization as markers for cells. Macromol. Chem. Phys. 206:2440-49
    • (2005) Macromol. Chem. Phys. , vol.206 , pp. 2440-2449
    • Holzapfel, V.1    Musyanovych, A.2    Landfester, K.3    Lorenz, M.R.4    Mailänder, V.5
  • 59
    • 80055102868 scopus 로고    scopus 로고
    • Criteria impacting the cellular uptake of nanoparticles: A study emphasizing polymer type and surfactant effects
    • MusyanovychA,Dausend J, Dass M, Walther P,MailänderV,LandfesterK. 2011. Criteria impacting the cellular uptake of nanoparticles: A study emphasizing polymer type and surfactant effects. Acta Biomater. 7:4160-68
    • (2011) Acta Biomater. , vol.7 , pp. 4160-4168
    • Musyanovych, A.1    Dausend, J.2    Dass, M.3    Walther, P.4    Mailänder, V.5    Landfester, K.6
  • 60
    • 84884933619 scopus 로고    scopus 로고
    • Nanosized drug delivery vectors and the reticuloendothelial system
    • Dordrecht, Neth. Springer, ed. A Prokop
    • Kaminskas LM, Boyd BJ. 2011. Nanosized drug delivery vectors and the reticuloendothelial system. In Intracellular Delivery, ed. A Prokop, pp. 155-78. Dordrecht, Neth.: Springer
    • (2011) Intracellular Delivery , pp. 155-178
    • Kaminskas, L.M.1    Boyd, B.J.2
  • 61
    • 60549105531 scopus 로고    scopus 로고
    • Long-circulating polymeric nanoparticles bearing a combinatorial coating of PEG and water-soluble chitosan
    • Sheng Y, Liu C, Yuan Y, Tao X, Yang F, et al. 2009. Long-circulating polymeric nanoparticles bearing a combinatorial coating of PEG and water-soluble chitosan. Biomaterials 30:2340-48
    • (2009) Biomaterials , vol.30 , pp. 2340-2348
    • Sheng, Y.1    Liu, C.2    Yuan, Y.3    Tao, X.4    Yang, F.5
  • 62
    • 0029360414 scopus 로고
    • The controlled intravenous delivery of drugs using PEG-coated sterically stabilized nanospheres
    • Gref R, Domb A, Quellec P, Blunk T, Müller RH, et al. 1995. The controlled intravenous delivery of drugs using PEG-coated sterically stabilized nanospheres. Adv. Drug Deliv. Rev. 16:215-33
    • (1995) Adv. Drug Deliv. Rev. , vol.16 , pp. 215-233
    • Gref, R.1    Domb, A.2    Quellec, P.3    Blunk, T.4    Müller, R.H.5
  • 63
    • 33748797672 scopus 로고    scopus 로고
    • Macrophage uptake of core-shell nanoparticles surface modified with poly(ethylene glycol)
    • Zahr AS, Davis CA, Pishko MV. 2006. Macrophage uptake of core-shell nanoparticles surface modified with poly(ethylene glycol). Langmuir 22:8178-85
    • (2006) Langmuir , vol.22 , pp. 8178-8185
    • Zahr, A.S.1    Davis, C.A.2    Pishko, M.V.3
  • 65
    • 67649491055 scopus 로고    scopus 로고
    • Understanding biophysicochemical interactions at the nano-bio interface
    • Nel AE, Mädler L, Velegol D, Xia T, Hoek EMV, et al. 2009. Understanding biophysicochemical interactions at the nano-bio interface. Nat. Mater. 8:543-57
    • (2009) Nat. Mater. , vol.8 , pp. 543-557
    • Nel, A.E.1    Mädler, L.2    Velegol, D.3    Xia, T.4    Hoek, E.M.V.5
  • 66
    • 0029379537 scopus 로고
    • Surface modification of nanoparticles to oppose uptake by the mononuclear phagocyte system
    • Storm G, Belliot SO, Daemen T, Lasic DD. 1995. Surface modification of nanoparticles to oppose uptake by the mononuclear phagocyte system. Adv. Drug Deliv. Rev. 17:31-48
    • (1995) Adv. Drug Deliv. Rev. , vol.17 , pp. 31-48
    • Storm, G.1    Belliot, S.O.2    Daemen, T.3    Lasic, D.D.4
  • 67
    • 28844488494 scopus 로고    scopus 로고
    • Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles
    • Owens DE 3rd, Peppas NA. 2006. Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles. Int. J. Pharm. 307:93-102
    • (2006) Int. J. Pharm. , vol.307 , pp. 93-102
    • Owens, D.E.1    Peppas, N.A.2
  • 68
    • 77955175216 scopus 로고    scopus 로고
    • Strategies in the design of nanoparticles for therapeutic applications
    • Petros RA, DeSimone JM. 2010. Strategies in the design of nanoparticles for therapeutic applications. Nat. Rev. Drug Discov. 9:615-27
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 615-627
    • Petros, R.A.1    DeSimone, J.M.2
  • 69
    • 84906674581 scopus 로고    scopus 로고
    • Presentation modality of glycoconjugates modulates dendritic cell phenotype
    • HotalingNA, Ratner DM,Cummings RD, Babensee JE. 2014. Presentation modality of glycoconjugates modulates dendritic cell phenotype. Biomater. Sci. 2:1426-39
    • (2014) Biomater. Sci. , vol.2 , pp. 1426-1439
    • Hotaling, N.A.1    Ratner, D.M.2    Cummings, R.D.3    Babensee, J.E.4
  • 70
    • 84949484380 scopus 로고    scopus 로고
    • Macrophage chitin binding proteins in phagocytosis and M1 activation in response to chitin microparticles
    • Shibata Y, Kogiso M, Huang C-J, Nouri-Shirazi M, Mizoguchi E, Dorey CK. 2012. Macrophage chitin binding proteins in phagocytosis and M1 activation in response to chitin microparticles. J. Immunol. 188:172.27
    • (2012) J. Immunol. , vol.188 , pp. 172-182
    • Shibata, Y.1    Kogiso, M.2    Huang, C.-J.3    Nouri-Shirazi, M.4    Mizoguchi, E.5    Dorey, C.K.6
  • 71
    • 84860335491 scopus 로고    scopus 로고
    • Innate immunity mediates follicular transport of particulate but not soluble protein antigen
    • Link A, Zabel F, Schnetzler Y, Titz A, Brombacher F, Bachmann MF. 2012. Innate immunity mediates follicular transport of particulate but not soluble protein antigen. J. Immunol. 188:3724-33
    • (2012) J. Immunol. , vol.188 , pp. 3724-3733
    • Link, A.1    Zabel, F.2    Schnetzler, Y.3    Titz, A.4    Brombacher, F.5    Bachmann, M.F.6
  • 72
    • 47849097202 scopus 로고    scopus 로고
    • Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
    • Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, et al. 2008. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat. Immunol. 9:847-56
    • (2008) Nat. Immunol. , vol.9 , pp. 847-856
    • Hornung, V.1    Bauernfeind, F.2    Halle, A.3    Samstad, E.O.4    Kono, H.5
  • 73
    • 78650610580 scopus 로고    scopus 로고
    • Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1and IL-1
    • Yazdi AS, Guarda G, Riteau N, Drexler SK, Tardivel A, et al. 2010. Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1 and IL-1. PNAS 107:19449-54
    • (2010) PNAS , vol.107 , pp. 19449-19454
    • Yazdi, A.S.1    Guarda, G.2    Riteau, N.3    Drexler, S.K.4    Tardivel, A.5
  • 74
    • 67349272344 scopus 로고    scopus 로고
    • Inflammasome-Activating nanoparticles as modular systems for optimizing vaccine efficacy
    • Demento SL, Eisenbarth SC, Foellmer HG, Platt C, Caplan MJ, et al. 2009. Inflammasome-Activating nanoparticles as modular systems for optimizing vaccine efficacy. Vaccine 27:3013-21
    • (2009) Vaccine , vol.27 , pp. 3013-3021
    • Demento, S.L.1    Eisenbarth, S.C.2    Foellmer, H.G.3    Platt, C.4    Caplan, M.J.5
  • 75
    • 78049361384 scopus 로고    scopus 로고
    • TLR9-targeted biodegradable nanoparticles as immunization vectors protect against West Nile encephalitis
    • Demento SL, Bonafé N, Cui W, Kaech SM, Caplan MJ, et al. 2010. TLR9-targeted biodegradable nanoparticles as immunization vectors protect against West Nile encephalitis. J. Immunol. 185:2989-97
    • (2010) J. Immunol. , vol.185 , pp. 2989-2997
    • Demento, S.L.1    Bonafé, N.2    Cui, W.3    Kaech, S.M.4    Caplan, M.J.5
  • 76
    • 80053161466 scopus 로고    scopus 로고
    • In situ engineering of the lymph node microenvironment via intranodal injection of adjuvant-releasing polymer particles
    • Jewell CM, López SCB, Irvine DJ. 2011. In situ engineering of the lymph node microenvironment via intranodal injection of adjuvant-releasing polymer particles. PNAS 108:15745-50
    • (2011) PNAS , vol.108 , pp. 15745-15750
    • Jewell, C.M.1    López, S.C.B.2    Irvine, D.J.3
  • 77
    • 78650576197 scopus 로고    scopus 로고
    • Use of defined TLR ligands as adjuvants within human vaccines
    • Duthie MS, Windish HP, Fox CB, Reed SG. 2011. Use of defined TLR ligands as adjuvants within human vaccines. Immunol. Rev. 239:178-96
    • (2011) Immunol. Rev. , vol.239 , pp. 178-196
    • Duthie, M.S.1    Windish, H.P.2    Fox, C.B.3    Reed, S.G.4
  • 78
    • 84856387516 scopus 로고    scopus 로고
    • Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction
    • Moon JJ, Suh H, Li AV, Ockenhouse CF, Yadava A, Irvine DJ. 2012. Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction. PNAS 109:1080-85
    • (2012) PNAS , vol.109 , pp. 1080-1085
    • Moon, J.J.1    Suh, H.2    Li, A.V.3    Ockenhouse, C.F.4    Yadava, A.5    Irvine, D.J.6
  • 79
    • 79951899834 scopus 로고    scopus 로고
    • Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses
    • Moon JJ, Suh H, Bershteyn A, Stephan MT, Liu H, et al. 2011. Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses. Nat. Mater. 10:243-51
    • (2011) Nat. Mater. , vol.10 , pp. 243-251
    • Moon, J.J.1    Suh, H.2    Bershteyn, A.3    Stephan, M.T.4    Liu, H.5
  • 80
    • 0037343587 scopus 로고    scopus 로고
    • Biodegradable micro-And nanoparticles as long-term delivery vehicles for interferon
    • Sánchez A, Tobó M, González L, Fabra A, Alonso MJ. 2003. Biodegradable micro-And nanoparticles as long-term delivery vehicles for interferon-. Eur. J. Pharm. Sci. 18:221-29
    • (2003) Eur. J. Pharm. Sci. , vol.18 , pp. 221-229
    • Sánchez, A.1    Tobó, M.2    González, L.3    Fabra, A.4    Alonso, M.J.5
  • 81
    • 0031060125 scopus 로고    scopus 로고
    • Characterization of PLGA microspheres for the controlled delivery of IL-1 for tumor immunotherapy
    • Chen L, Apte RN, Cohen S. 1997. Characterization of PLGA microspheres for the controlled delivery of IL-1 for tumor immunotherapy. J. Control. Release 43:261-72
    • (1997) J. Control. Release , vol.43 , pp. 261-272
    • Chen, L.1    Apte, R.N.2    Cohen, S.3
  • 83
    • 0035962385 scopus 로고    scopus 로고
    • PEGylated polycyanoacrylate nanoparticles as tumor necrosis factor-carriers
    • Li Y-P, PeiY-Y,ZhouZ-H, ZhangX-Y,GuZ-H, et al. 2001. PEGylated polycyanoacrylate nanoparticles as tumor necrosis factor-carriers. J. Control. Release 71:287-96
    • (2001) J. Control. Release , vol.71 , pp. 287-296
    • Li, Y.-P.1    PeiY-Y2    ZhouZ-H3    ZhangX-Y4    GuZ-H5
  • 84
    • 0027141113 scopus 로고
    • Controlled release, biodegradable cytokine depots: A new approach in cancer vaccine design
    • Golumbek PT, Azhari R, Jaffee EM, Levitsky HI, Lazenby A, et al. 1993. Controlled release, biodegradable cytokine depots: A new approach in cancer vaccine design. Cancer Res. 53:5841-44
    • (1993) Cancer Res. , vol.53 , pp. 5841-5844
    • Golumbek, P.T.1    Azhari, R.2    Jaffee, E.M.3    Levitsky, H.I.4    Lazenby, A.5
  • 85
    • 0034069615 scopus 로고    scopus 로고
    • Controlled release of transforming growth factor 1 from biodegradable polymer microparticles
    • Lu L, Stamatas GN, Mikos AG. 2000. Controlled release of transforming growth factor 1 from biodegradable polymer microparticles. J. Biomed. Mater. Res. 50:440-51
    • (2000) J. Biomed. Mater. Res. , vol.50 , pp. 440-451
    • Lu, L.1    Stamatas, G.N.2    Mikos, A.G.3
  • 86
    • 79956114010 scopus 로고    scopus 로고
    • Pathogen-Associated molecular patterns on biomaterials: A paradigm for engineering new vaccines
    • Demento SL, Siefert AL, Bandyopadhyay A, Sharp FA, Fahmy TM. 2011. Pathogen-Associated molecular patterns on biomaterials: A paradigm for engineering new vaccines. Trends Biotechnol. 29:294-306
    • (2011) Trends Biotechnol. , vol.29 , pp. 294-306
    • Demento, S.L.1    Siefert, A.L.2    Bandyopadhyay, A.3    Sharp, F.A.4    Fahmy, T.M.5
  • 87
    • 84857257866 scopus 로고    scopus 로고
    • Synthetic mast cell granules as adjuvants to promote and polarize immunity in lymph nodes
    • St. John AL, Chan CY, Staats HF, Leong KW, Abraham SN. 2012. Synthetic mast cell granules as adjuvants to promote and polarize immunity in lymph nodes. Nat. Mater. 11:250-57
    • (2012) Nat. Mater. , vol.11 , pp. 250-257
    • St. John, A.L.1    Chan, C.Y.2    Staats, H.F.3    Leong, K.W.4    Abraham, S.N.5
  • 88
    • 0033786776 scopus 로고    scopus 로고
    • Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand
    • Bielekova B, Goodwin B, Richert N, Cortese I, Kondo T, et al. 2000. Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand. Nat. Med. 6:1167-75
    • (2000) Nat. Med. , vol.6 , pp. 1167-1175
    • Bielekova, B.1    Goodwin, B.2    Richert, N.3    Cortese, I.4    Kondo, T.5
  • 89
    • 82955198543 scopus 로고    scopus 로고
    • A phase III study evaluating the efficacy and safety of MBP8298 in secondary progressive MS
    • Freedman MS, Bar-Or A, Oger J, Traboulsee A, Patry D, et al. 2011. A phase III study evaluating the efficacy and safety of MBP8298 in secondary progressive MS. Neurology 77:1551-60
    • (2011) Neurology , vol.77 , pp. 1551-1560
    • Freedman, M.S.1    Bar-Or, A.2    Oger, J.3    Traboulsee, A.4    Patry, D.5
  • 90
    • 22144479728 scopus 로고    scopus 로고
    • Differential induction of IgE-mediated anaphylaxis after soluble versus cell-bound tolerogenic peptide therapy of autoimmune encephalomyelitis
    • Smith CE, Eagar TN, Strominger JL, Miller SD. 2005. Differential induction of IgE-mediated anaphylaxis after soluble versus cell-bound tolerogenic peptide therapy of autoimmune encephalomyelitis. PNAS 102:9595-600
    • (2005) PNAS , vol.102 , pp. 9595-9600
    • Smith, C.E.1    Eagar, T.N.2    Strominger, J.L.3    Miller, S.D.4
  • 91
    • 84875822264 scopus 로고    scopus 로고
    • Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus in mice
    • Look M, Stern E, Wang QA, DiPlacido LD, Kashgarian M, et al. 2013. Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus in mice. J. Clin. Investig. 123:1741-49
    • (2013) J. Clin. Investig. , vol.123 , pp. 1741-1749
    • Look, M.1    Stern, E.2    Wang, Q.A.3    DiPlacido, L.D.4    Kashgarian, M.5
  • 92
    • 80054764032 scopus 로고    scopus 로고
    • Liposomal encapsulation of glucocorticoids alters their mode of action in the treatment of experimental autoimmune encephalomyelitis
    • Schweingruber N, Haine A, Tiede K, Karabinskaya A, van den Brandt J, et al. 2011. Liposomal encapsulation of glucocorticoids alters their mode of action in the treatment of experimental autoimmune encephalomyelitis. J. Immunol. 187:4310-18
    • (2011) J. Immunol. , vol.187 , pp. 4310-4318
    • Schweingruber, N.1    Haine, A.2    Tiede, K.3    Karabinskaya, A.4    Van Den Brandt, J.5
  • 93
  • 94
    • 72149128473 scopus 로고    scopus 로고
    • Immune response to controlled release of immunomodulating peptides in a murine experimental autoimmune encephalomyelitis (EAE) model
    • Zhao H, Kiptoo P, Williams TD, Siahaan TJ, Topp EM. 2010. Immune response to controlled release of immunomodulating peptides in a murine experimental autoimmune encephalomyelitis (EAE) model. J. Control. Release 141:145-52
    • (2010) J. Control. Release , vol.141 , pp. 145-152
    • Zhao, H.1    Kiptoo, P.2    Williams, T.D.3    Siahaan, T.J.4    Topp, E.M.5
  • 95
    • 16244415192 scopus 로고    scopus 로고
    • Leukemia inhibitory factor is linked to regulatory transplantation tolerance
    • Metcalfe SM, Watson TJ, Shurey S, Adams E, Green CJ. 2005. Leukemia inhibitory factor is linked to regulatory transplantation tolerance. Transplantation 79:726-30
    • (2005) Transplantation , vol.79 , pp. 726-730
    • Metcalfe, S.M.1    Watson, T.J.2    Shurey, S.3    Adams, E.4    Green, C.J.5
  • 96
    • 79952934026 scopus 로고    scopus 로고
    • Modulation of CD4+ T lymphocyte lineage outcomes with targeted, nanoparticle-mediated cytokine delivery
    • Park J, GaoW,Whiston R, Strom TB, Metcalfe S, Fahmy TM. 2011. Modulation of CD4+ T lymphocyte lineage outcomes with targeted, nanoparticle-mediated cytokine delivery. Mol. Pharm. 8:143-52
    • (2011) Mol. Pharm. , vol.8 , pp. 143-152
    • Park, J.1    Gao, W.2    Whiston, R.3    Strom, T.B.4    Metcalfe, S.5    Fahmy, T.M.6
  • 97
    • 74049160009 scopus 로고    scopus 로고
    • Mechanisms maintaining peripheral tolerance
    • Mueller DL. 2010. Mechanisms maintaining peripheral tolerance. Nat. Immunol. 11:21-27
    • (2010) Nat. Immunol. , vol.11 , pp. 21-27
    • Mueller, D.L.1
  • 98
    • 84872027397 scopus 로고    scopus 로고
    • Clearing the dead: Apoptotic cell sensing, recognition, engulfment, and digestion
    • Hochreiter-Hufford A, Ravichandran KS. 2013. Clearing the dead: Apoptotic cell sensing, recognition, engulfment, and digestion. Cold Spring Harb. Perspect. Biol. 5:a008748
    • (2013) Cold Spring Harb. Perspect. Biol. , vol.5 , pp. a008748
    • Hochreiter-Hufford, A.1    Ravichandran, K.S.2
  • 99
    • 55749114418 scopus 로고    scopus 로고
    • ECDI-fixed allogeneic splenocytes induce donor-specific tolerance for long-term survival of islet transplants via two distinct mechanisms
    • Luo XR, Pothoven KL,McCarthy D, DeGutes M, Martin A, et al. 2008. ECDI-fixed allogeneic splenocytes induce donor-specific tolerance for long-term survival of islet transplants via two distinct mechanisms. PNAS 105:14527-32
    • (2008) PNAS , vol.105 , pp. 14527-14532
    • Luo, X.R.1    Pothoven, K.L.2    McCarthy, D.3    DeGutes, M.4    Martin, A.5
  • 100
    • 84870953123 scopus 로고    scopus 로고
    • Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis
    • Getts DR,Martin AJ, McCarthy DP,Terry RL,HunterZN, et al. 2012. Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis. Nat. Biotechnol. 30:1217-24
    • (2012) Nat. Biotechnol. , vol.30 , pp. 1217-1224
    • Getts, D.R.1    Martin, A.J.2    McCarthy, D.P.3    Terry, R.L.4    Hunter, Z.N.5
  • 102
    • 84887014101 scopus 로고    scopus 로고
    • All-trans retinoic acid and rapamycin synergize with transforming growth factor-1 to induce regulatoryTcells but confer different migratory capacities
    • Jhunjhunwala S, Chen LC, Nichols EE, Thomson AW, Raimondi G, Little SR. 2013. All-trans retinoic acid and rapamycin synergize with transforming growth factor-1 to induce regulatoryTcells but confer different migratory capacities. J. Leukoc. Biol. 94:981-89
    • (2013) J. Leukoc. Biol. , vol.94 , pp. 981-989
    • Jhunjhunwala, S.1    Chen, L.C.2    Nichols, E.E.3    Thomson, A.W.4    Raimondi, G.5    Little, S.R.6
  • 103
    • 84859494040 scopus 로고    scopus 로고
    • Controlled release formulations of IL-2, TGF-1 and rapamycin for the induction of regulatory T cells
    • Jhunjhunwala S, Balmert SC, Raimondi G, Dons E, Nichols EE, et al. 2012. Controlled release formulations of IL-2, TGF-1 and rapamycin for the induction of regulatory T cells. J. Control. Release 159:78-84
    • (2012) J. Control. Release , vol.159 , pp. 78-84
    • Jhunjhunwala, S.1    Balmert, S.C.2    Raimondi, G.3    Dons, E.4    Nichols, E.E.5
  • 104
    • 84863949288 scopus 로고    scopus 로고
    • Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis
    • Yeste A, Nadeau M, Burns EJ, Weiner HL, Quintana FJ. 2012. Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis. PNAS 109:11270-75
    • (2012) PNAS , vol.109 , pp. 11270-11275
    • Yeste, A.1    Nadeau, M.2    Burns, E.J.3    Weiner, H.L.4    Quintana, F.J.5
  • 105
    • 84857783764 scopus 로고    scopus 로고
    • Strategies to reduce dendritic cell activation through functional biomaterial design
    • Hume PS, He J, Haskins K, Anseth KS. 2012. Strategies to reduce dendritic cell activation through functional biomaterial design. Biomaterials 33:3615-25
    • (2012) Biomaterials , vol.33 , pp. 3615-3625
    • Hume, P.S.1    He, J.2    Haskins, K.3    Anseth, K.S.4
  • 106
    • 38949135155 scopus 로고    scopus 로고
    • The microanatomy of T-cell responses
    • Lammermann T, Sixt M. 2008. The microanatomy of T-cell responses. Immunol. Rev. 221:26-43
    • (2008) Immunol. Rev. , vol.221 , pp. 26-43
    • Lammermann, T.1    Sixt, M.2
  • 107
    • 34247149876 scopus 로고    scopus 로고
    • The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles
    • Pape KA, CatronDM, Itano AA, JenkinsMK. 2007. The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles. Immunity 26:491-502
    • (2007) Immunity , vol.26 , pp. 491-502
    • Pape, K.A.1    Catron, D.M.2    Itano, A.A.3    Jenkins, M.K.4
  • 108
    • 33646480406 scopus 로고    scopus 로고
    • In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfide) nanoparticles
    • Reddy ST, Rehor A, Schmoekel HG, Hubbell JA, Swartz MA. 2006. In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfide) nanoparticles. J. Control. Release 112:26-34
    • (2006) J. Control. Release , vol.112 , pp. 26-34
    • Reddy, S.T.1    Rehor, A.2    Schmoekel, H.G.3    Hubbell, J.A.4    Swartz, M.A.5
  • 110
    • 11844253824 scopus 로고    scopus 로고
    • Oxidation-sensitive polymeric nanoparticles
    • Rehor A,Hubbell JA, Tirelli N. 2005. Oxidation-sensitive polymeric nanoparticles. Langmuir 21:411-17
    • (2005) Langmuir , vol.21 , pp. 411-417
    • Rehor, A.1    Hubbell, J.A.2    Tirelli, N.3
  • 111
    • 4344697146 scopus 로고    scopus 로고
    • Size-dependent immunogenicity: Therapeutic and protective properties of nano-vaccines against tumors
    • Fifis T, Gamvrellis A, Crimeen-Irwin B, Pietersz GA, Li J, et al. 2004. Size-dependent immunogenicity: therapeutic and protective properties of nano-vaccines against tumors. J. Immunol. 173:3148-54
    • (2004) J. Immunol. , vol.173 , pp. 3148-3154
    • Fifis, T.1    Gamvrellis, A.2    Crimeen-Irwin, B.3    Pietersz, G.A.4    Li, J.5
  • 113
    • 84871956263 scopus 로고    scopus 로고
    • Biodegradable particles as vaccine delivery systems: Size matters
    • Joshi VB, Geary SM, Salem AK. 2013. Biodegradable particles as vaccine delivery systems: size matters. AAPS J. 15:85-94
    • (2013) AAPS J. , vol.15 , pp. 85-94
    • Joshi, V.B.1    Geary, S.M.2    Salem, A.K.3
  • 114
    • 17644371966 scopus 로고    scopus 로고
    • Mucosal immunity and vaccines
    • Holmgren J, Czerkinsky C. 2005. Mucosal immunity and vaccines. Nat. Med. 11:S45-53
    • (2005) Nat. Med. , vol.11 , pp. S45-53
    • Holmgren, J.1    Czerkinsky, C.2
  • 115
    • 33644836224 scopus 로고    scopus 로고
    • Mucosal vaccines: The promise and the challenge
    • Neutra MR, Kozlowski PA. 2006. Mucosal vaccines: the promise and the challenge. Nat. Rev. Immunol. 6:148-58
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 148-158
    • Neutra, M.R.1    Kozlowski, P.A.2
  • 116
    • 81055130325 scopus 로고    scopus 로고
    • Nanoparticle conjugation of antigen enhances cytotoxic T-cell responses in pulmonary vaccination
    • Nembrini C, Stano A, Dane KY, Ballester M, van der Vlies AJ, et al. 2011. Nanoparticle conjugation of antigen enhances cytotoxic T-cell responses in pulmonary vaccination. PNAS 108:E989-97
    • (2011) PNAS , vol.108 , pp. E989-E997
    • Nembrini, C.1    Stano, A.2    Dane, K.Y.3    Ballester, M.4    Van Der Vlies, A.J.5
  • 117
    • 80052339594 scopus 로고    scopus 로고
    • Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis
    • Ballester M, Nembrini C, Dhar N, de Titta A, de Piano C, et al. 2011. Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis. Vaccine 29:6959-66
    • (2011) Vaccine , vol.29 , pp. 6959-6966
    • Ballester, M.1    Nembrini, C.2    Dhar, N.3    De Titta, A.4    De Piano, C.5
  • 118
    • 84862519335 scopus 로고    scopus 로고
    • Mucus-penetrating nanoparticles for vaginal drug delivery protect against herpes simplex virus
    • Ensign LM, Tang BC, Wang Y-Y, Tse TA, Hoen T, et al. 2012. Mucus-penetrating nanoparticles for vaginal drug delivery protect against herpes simplex virus. Sci. Transl. Med. 4:138ra79
    • (2012) Sci. Transl. Med. , vol.4 , pp. 138ra79
    • Ensign, L.M.1    Tang, B.C.2    Wang, Y.-Y.3    Tse, T.A.4    Hoen, T.5
  • 119
    • 60149111908 scopus 로고    scopus 로고
    • Mucus-penetrating nanoparticles for drug and gene delivery tomucosal tissues
    • Lai SK,WangYY, Hanes J. 2009. Mucus-penetrating nanoparticles for drug and gene delivery tomucosal tissues. Adv. Drug Deliv. Rev. 61:158-71
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 158-171
    • Lai, S.K.1    Wang, Y.Y.2    Hanes, J.3
  • 120
    • 76249115874 scopus 로고    scopus 로고
    • Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses
    • Lai SK, Wang Y-Y, Hida K, Cone R, Hanes J. 2010. Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses. PNAS 107:598-603
    • (2010) PNAS , vol.107 , pp. 598-603
    • Lai, S.K.1    Wang, Y.-Y.2    Hida, K.3    Cone, R.4    Hanes, J.5
  • 121
    • 84862893004 scopus 로고    scopus 로고
    • Spatiotemporally separated antigen uptake by alveolar dendritic cells and airway presentation toTcells in the lung
    • Thornton EE, Looney MR, BoseO, Sen D, Sheppard D, et al. 2012. Spatiotemporally separated antigen uptake by alveolar dendritic cells and airway presentation toTcells in the lung. J. Exp.Med. 209:1183-99
    • (2012) J. Exp.Med. , vol.209 , pp. 1183-1199
    • Thornton, E.E.1    Looney, M.R.2    Bose, O.3    Sen, D.4    Sheppard, D.5
  • 122
    • 84884676871 scopus 로고    scopus 로고
    • Generation of effector memoryTcell-based mucosal and systemic immunity with pulmonary nanoparticle vaccination
    • Li AV,Moon JJ, AbrahamW, Suh H, Elkhader J, et al. 2013. Generation of effector memoryTcell-based mucosal and systemic immunity with pulmonary nanoparticle vaccination. Sci. Transl. Med. 5:204ra130
    • (2013) Sci. Transl. Med. , vol.5 , pp. 204ra130
    • Li, A.V.1    Moon, J.J.2    Abraham, W.3    Suh, H.4    Elkhader, J.5
  • 123
    • 77957738079 scopus 로고    scopus 로고
    • Vaccine delivery by polymeric vehicles in the mouse reproductive tract induces sustained local and systemic immunity
    • Kuo-Haller P, Cu Y, Blum J, Appleton JA, Saltzman WM. 2010. Vaccine delivery by polymeric vehicles in the mouse reproductive tract induces sustained local and systemic immunity. Mol. Pharm. 7:1585-95
    • (2010) Mol. Pharm. , vol.7 , pp. 1585-1595
    • Kuo-Haller, P.1    Cu, Y.2    Blum, J.3    Appleton, J.A.4    Saltzman, W.M.5
  • 124
    • 0037174674 scopus 로고    scopus 로고
    • Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
    • Dudley ME,Wunderlich JR, Robbins PF, Yang JC, Hwu P, et al. 2002. Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science 298:850-54
    • (2002) Science , vol.298 , pp. 850-854
    • Dudley, M.E.1    Wunderlich, J.R.2    Robbins, P.F.3    Yang, J.C.4    Hwu, P.5
  • 125
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: Moving beyond current vaccines
    • Rosenberg SA, Yang JC, Restifo NP. 2004. Cancer immunotherapy: moving beyond current vaccines. Nat. Med. 10:909-15
    • (2004) Nat. Med. , vol.10 , pp. 909-915
    • Rosenberg, S.A.1    Yang, J.C.2    Restifo, N.P.3
  • 126
    • 45549099784 scopus 로고    scopus 로고
    • Treatment ofmetastaticmelanoma with autologous CD4+ T cells against NY-ESO-1
    • Hunder NN, WallenH,Cao J, HendricksDW, Reilly JZ, et al. 2008. Treatment ofmetastaticmelanoma with autologous CD4+ T cells against NY-ESO-1. N. Engl. J. Med. 358:2698-703
    • (2008) N. Engl. J. Med. , vol.358 , pp. 2698-2703
    • Hunder, N.N.1    Wallen, H.2    Cao, J.3    Hendricks, D.W.4    Reilly, J.Z.5
  • 127
    • 36549077641 scopus 로고    scopus 로고
    • Adoptive cellular therapy for cytomegalovirus infection following allogeneic stem cell transplantation using virus-specific T cells
    • Mackinnon S, Thomson K, Verfuerth S, Peggs K, Lowdell M. 2008. Adoptive cellular therapy for cytomegalovirus infection following allogeneic stem cell transplantation using virus-specific T cells. Blood Cells Mol. Dis. 40:63-67
    • (2008) Blood Cells Mol. Dis. , vol.40 , pp. 63-67
    • Mackinnon, S.1    Thomson, K.2    Verfuerth, S.3    Peggs, K.4    Lowdell, M.5
  • 128
    • 33749624177 scopus 로고    scopus 로고
    • Cancer regression in patients after transfer of genetically engineered lymphocytes
    • Morgan RA, Dudley ME, Wunderlich JR, Hughes MS, Yang JC, et al. 2006. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 314:126-29
    • (2006) Science , vol.314 , pp. 126-129
    • Morgan, R.A.1    Dudley, M.E.2    Wunderlich, J.R.3    Hughes, M.S.4    Yang, J.C.5
  • 129
    • 70350511426 scopus 로고    scopus 로고
    • Safety and immunologic effects of IL-15 administration in nonhuman primates
    • Berger C, Berger M, Hackman RC, Gough M, Elliott C, et al. 2009. Safety and immunologic effects of IL-15 administration in nonhuman primates. Blood 114:2417-26
    • (2009) Blood , vol.114 , pp. 2417-2426
    • Berger, C.1    Berger, M.2    Hackman, R.C.3    Gough, M.4    Elliott, C.5
  • 130
    • 0023203708 scopus 로고
    • Recombinant interleukin-2 toxicity, pharmacokinetics, and immunomodulatory effects in a phase i trial
    • Thompson JA, Lee DJ, Cox WW, Lindgren CG, Collins C, et al. 1987. Recombinant interleukin-2 toxicity, pharmacokinetics, and immunomodulatory effects in a phase I trial. Cancer Res. 47:4202-7
    • (1987) Cancer Res. , vol.47 , pp. 4202-4207
    • Thompson, J.A.1    Lee, D.J.2    Cox, W.W.3    Lindgren, C.G.4    Collins, C.5
  • 131
    • 77956428880 scopus 로고    scopus 로고
    • Therapeutic cell engineeringwith surfaceconjugated synthetic nanoparticles
    • StephanMT, Moon JJ,UmSH, Bershteyn A, Irvine DJ. 2010. Therapeutic cell engineeringwith surfaceconjugated synthetic nanoparticles. Nat. Med. 16:1035-41
    • (2010) Nat. Med. , vol.16 , pp. 1035-1041
    • Stephan, M.T.1    Moon, J.J.2    Um, S.H.3    Bershteyn, A.4    Irvine, D.J.5
  • 132
    • 84861348645 scopus 로고    scopus 로고
    • Synapse-directed delivery of immunomodulators using T-cell-conjugated nanoparticles
    • Stephan MT, Stephan SB, Bak P, Chen J, Irvine DJ. 2012. Synapse-directed delivery of immunomodulators using T-cell-conjugated nanoparticles. Biomaterials 33:5776-87
    • (2012) Biomaterials , vol.33 , pp. 5776-5787
    • Stephan, M.T.1    Stephan, S.B.2    Bak, P.3    Chen, J.4    Irvine, D.J.5
  • 133
    • 84887121506 scopus 로고    scopus 로고
    • In vivo targeting of adoptively transferred T-cells with antibody-And cytokine-conjugated liposomes
    • Zheng Y, Stephan MT, Gai SA, Abraham W, Shearer A, Irvine DJ. 2013. In vivo targeting of adoptively transferred T-cells with antibody-And cytokine-conjugated liposomes. J. Control. Release 172:426-35
    • (2013) J. Control. Release , vol.172 , pp. 426-435
    • Zheng, Y.1    Stephan, M.T.2    Gai, S.A.3    Abraham, W.4    Shearer, A.5    Irvine, D.J.6
  • 134
    • 40649095267 scopus 로고    scopus 로고
    • Lymphoid tissue engineering: Invoking lymphoid tissue neogenesis in immunotherapy and models of immunity
    • Irvine DJ, Stachowiak AN, Hori Y. 2008. Lymphoid tissue engineering: invoking lymphoid tissue neogenesis in immunotherapy and models of immunity. Semin. Immunol. 20:137-46
    • (2008) Semin. Immunol. , vol.20 , pp. 137-146
    • Irvine, D.J.1    Stachowiak, A.N.2    Hori, Y.3
  • 135
    • 84874207557 scopus 로고    scopus 로고
    • Application of tissue engineering to the immune system: Development of artificial lymph nodes
    • Cupedo T, Stroock A, Coles M. 2012. Application of tissue engineering to the immune system: development of artificial lymph nodes. Front. Immunol. 3:1-6
    • (2012) Front. Immunol. , vol.3 , pp. 1-6
    • Cupedo, T.1    Stroock, A.2    Coles, M.3
  • 138
    • 33751577815 scopus 로고    scopus 로고
    • Biomaterial-based notch signaling for the differentiation of hematopoietic stem cells into T cells
    • Taqvi S,Dixit L, RoyK. 2006. Biomaterial-based notch signaling for the differentiation of hematopoietic stem cells into T cells. J. Biomed. Mater. Res. A 79:689-97
    • (2006) J. Biomed. Mater. Res. A , vol.79 , pp. 689-697
    • Taqvi, S.1    Dixit, L.2    Roy, K.3
  • 139
    • 0037978900 scopus 로고    scopus 로고
    • Organogenesis of lymphoid tissues
    • Mebius RE. 2003. Organogenesis of lymphoid tissues. Nat. Rev. Immunol. 3:292-303
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 292-303
    • Mebius, R.E.1
  • 141
    • 11144268883 scopus 로고    scopus 로고
    • Generation of a synthetic lymphoid tissue-like organoid in mice
    • Suematsu S, Watanabe T. 2004. Generation of a synthetic lymphoid tissue-like organoid in mice. Nat. Biotechnol. 22:1539-45
    • (2004) Nat. Biotechnol. , vol.22 , pp. 1539-1545
    • Suematsu, S.1    Watanabe, T.2
  • 142
    • 77955975048 scopus 로고    scopus 로고
    • Artificial engineering of secondary lymphoid organs
    • ed. FWAlt. Amsterdam Elsevier
    • Tan JKH, Watanabe T. 2010. Artificial engineering of secondary lymphoid organs. In Advances in Immunology, Vol. 105, ed. FWAlt, pp. 131-157. Amsterdam: Elsevier
    • (2010) Advances in Immunology , vol.105 , pp. 131-157
    • Tan, J.K.H.1    Watanabe, T.2
  • 143
    • 34147154843 scopus 로고    scopus 로고
    • Artificial lymph nodes induce potent secondary immune responses in naive and immunodeficient mice
    • Okamoto N, Chihara R, Shimizu C, Nishimoto S, Watanabe T. 2007. Artificial lymph nodes induce potent secondary immune responses in naive and immunodeficient mice. J. Clin. Investig. 117:997-1007
    • (2007) J. Clin. Investig. , vol.117 , pp. 997-1007
    • Okamoto, N.1    Chihara, R.2    Shimizu, C.3    Nishimoto, S.4    Watanabe, T.5
  • 146
    • 70449570269 scopus 로고    scopus 로고
    • An immunologic model for rapid vaccine assessment-A clinical trial in a test tube
    • Higbee RG, Byers AM, Dhir V, Drake D, Fahlenkamp HG, et al. 2009. An immunologic model for rapid vaccine assessment-A clinical trial in a test tube. Altern. Lab. Anim. 37(Suppl. 1):19-27
    • (2009) Altern. Lab. Anim. , vol.37 , pp. 19-27
    • Higbee, R.G.1    Byers, A.M.2    Dhir, V.3    Drake, D.4    Fahlenkamp, H.G.5
  • 147
    • 34548780292 scopus 로고    scopus 로고
    • Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces
    • Woolf E, Grigorova I, Sagiv A, Grabovsky V, Feigelson SW, et al. 2007. Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces. Nat. Immunol. 8:1076-85
    • (2007) Nat. Immunol. , vol.8 , pp. 1076-1085
    • Woolf, E.1    Grigorova, I.2    Sagiv, A.3    Grabovsky, V.4    Feigelson, S.W.5
  • 148
    • 43049095762 scopus 로고    scopus 로고
    • Inverse opal hydrogel-collagen composite scaffolds as a supportive microenvironment for immune cell migration
    • Stachowiak AN, Irvine DJ. 2008. Inverse opal hydrogel-collagen composite scaffolds as a supportive microenvironment for immune cell migration. J. Biomed. Mater. Res. A 85:815-28
    • (2008) J. Biomed. Mater. Res. A , vol.85 , pp. 815-828
    • Stachowiak, A.N.1    Irvine, D.J.2
  • 149
    • 14844286184 scopus 로고    scopus 로고
    • Bioactive hydrogels with an ordered cellular structure combine interconnected macroporosity and robustmechanical properties
    • Stachowiak AN, Bershteyn A, Tzatzalos E, Irvine DJ. 2005. Bioactive hydrogels with an ordered cellular structure combine interconnected macroporosity and robustmechanical properties. Adv. Mater. 17:399-403
    • (2005) Adv. Mater. , vol.17 , pp. 399-403
    • Stachowiak, A.N.1    Bershteyn, A.2    Tzatzalos, E.3    Irvine, D.J.4
  • 150
    • 17644365138 scopus 로고    scopus 로고
    • Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs
    • Cyster JG. 2005. Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs. Annu. Rev. Immunol. 23:127-59
    • (2005) Annu. Rev. Immunol. , vol.23 , pp. 127-159
    • Cyster, J.G.1
  • 151
    • 70449713917 scopus 로고    scopus 로고
    • Fluid flow regulates stromal cell organization and CCL21 expression in a tissue-engineered lymph node microenvironment
    • Tomei AA, Siegert S, Britschgi MR, Luther SA, Swartz MA. 2009. Fluid flow regulates stromal cell organization and CCL21 expression in a tissue-engineered lymph node microenvironment. J. Immunol. 183:4273-83
    • (2009) J. Immunol. , vol.183 , pp. 4273-4283
    • Tomei, A.A.1    Siegert, S.2    Britschgi, M.R.3    Luther, S.A.4    Swartz, M.A.5
  • 152
    • 77953720628 scopus 로고    scopus 로고
    • In situ regulation of DC subsets and T cells mediates tumor regression in mice
    • Ali OA, Emerich D, Dranoff G,Mooney DJ. 2009. In situ regulation of DC subsets and T cells mediates tumor regression in mice. Sci. Transl. Med. 1:8ra19
    • (2009) Sci. Transl. Med. , vol.1 , pp. 8ra19
    • Ali, O.A.1    Emerich, D.2    Dranoff, G.3    Mooney, D.J.4
  • 153
    • 58949100114 scopus 로고    scopus 로고
    • Infection-mimicking materials to program dendritic cells in situ
    • Ali OA, Huebsch N, Cao L, Dranoff G, Mooney DJ. 2009. Infection-mimicking materials to program dendritic cells in situ. Nat. Mater. 8:151-58
    • (2009) Nat. Mater. , vol.8 , pp. 151-158
    • Ali, O.A.1    Huebsch, N.2    Cao, L.3    Dranoff, G.4    Mooney, D.J.5
  • 154
    • 84961289256 scopus 로고    scopus 로고
    • Injectable, spontaneously assembling, inorganic scaffoldsmodulate immune cells in vivo and increase vaccine efficacy
    • Kim J, Li WA, Choi Y, Lewin SA, Verbeke CS, et al. 2015. Injectable, spontaneously assembling, inorganic scaffoldsmodulate immune cells in vivo and increase vaccine efficacy. Nat. Biotechnol. 33:64-72
    • (2015) Nat. Biotechnol. , vol.33 , pp. 64-72
    • Kim, J.1    Li, W.A.2    Choi, Y.3    Lewin, S.A.4    Verbeke, C.S.5
  • 155
    • 67849084830 scopus 로고    scopus 로고
    • In-situ crosslinking hydrogels for combinatorial delivery of chemokines and siRNA-DNA carrying microparticles to dendritic cells
    • Singh A, Suri S, Roy K. 2009. In-situ crosslinking hydrogels for combinatorial delivery of chemokines and siRNA-DNA carrying microparticles to dendritic cells. Biomaterials 30:5187-200
    • (2009) Biomaterials , vol.30 , pp. 5187-5200
    • Singh, A.1    Suri, S.2    Roy, K.3
  • 156
    • 80054095576 scopus 로고    scopus 로고
    • An injectable synthetic immune-priming center mediates efficient T-cell class switching and T-helper 1 response against B cell lymphoma
    • Singh A, Qin H, Fernandez I,Wei J, Lin J, et al. 2011. An injectable synthetic immune-priming center mediates efficient T-cell class switching and T-helper 1 response against B cell lymphoma. J. Control. Release 155:184-92
    • (2011) J. Control. Release , vol.155 , pp. 184-192
    • Singh, A.1    Qin, H.2    Fernandez, I.3    Wei, J.4    Lin, J.5
  • 157
    • 56749179475 scopus 로고    scopus 로고
    • Efficient modulation of T-cell response by dual-mode, single-carrier delivery of cytokine-targeted siRNA and DNA vaccine to antigen-presenting cells
    • Singh A, Nie H, Ghosn B, Qin H, Kwak LW, Roy K. 2008. Efficient modulation of T-cell response by dual-mode, single-carrier delivery of cytokine-targeted siRNA and DNA vaccine to antigen-presenting cells. Mol. Ther. 16:2011-21
    • (2008) Mol. Ther. , vol.16 , pp. 2011-2021
    • Singh, A.1    Nie, H.2    Ghosn, B.3    Qin, H.4    Kwak, L.W.5    Roy, K.6
  • 158
    • 84866743713 scopus 로고    scopus 로고
    • Combination delivery of TGF-inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy
    • Park J, Wrzesinski SH, Stern E, Look M, Criscione J, et al. 2012. Combination delivery of TGF-inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy. Nat. Mater. 11:895-905
    • (2012) Nat. Mater. , vol.11 , pp. 895-905
    • Park, J.1    Wrzesinski, S.H.2    Stern, E.3    Look, M.4    Criscione, J.5
  • 159
    • 70349854888 scopus 로고    scopus 로고
    • Engulfing tumors with synthetic extracellular matrices for cancer immunotherapy
    • Hori Y, Stern PJ, Hynes RO, Irvine DJ. 2009. Engulfing tumors with synthetic extracellular matrices for cancer immunotherapy. Biomaterials 30:6757-67
    • (2009) Biomaterials , vol.30 , pp. 6757-6767
    • Hori, Y.1    Stern, P.J.2    Hynes, R.O.3    Irvine, D.J.4
  • 160
    • 64249117324 scopus 로고    scopus 로고
    • Modular injectable matrices based on alginate solution/ microspheremixtures that gel in situ and co-deliver immunomodulatory factors
    • Hori Y, Winans AM, Irvine DJ. 2009. Modular injectable matrices based on alginate solution/ microspheremixtures that gel in situ and co-deliver immunomodulatory factors. Acta Biomater. 5:969-82
    • (2009) Acta Biomater. , vol.5 , pp. 969-982
    • Hori, Y.1    Winans, A.M.2    Irvine, D.J.3
  • 161
    • 46749110694 scopus 로고    scopus 로고
    • Injectable dendritic cell-carrying alginate gels for immunization and immunotherapy
    • Hori Y, Winans AM, Huang CC, Horrigan EM, Irvine DJ. 2008. Injectable dendritic cell-carrying alginate gels for immunization and immunotherapy. Biomaterials 29:3671-82
    • (2008) Biomaterials , vol.29 , pp. 3671-3682
    • Hori, Y.1    Winans, A.M.2    Huang, C.C.3    Horrigan, E.M.4    Irvine, D.J.5
  • 162
    • 16344370564 scopus 로고    scopus 로고
    • T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell
    • González PA, Carreño LJ, Coombs D, Mora JE, Palmieri E, et al. 2005. T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell. PNAS 102:4824-29
    • (2005) PNAS , vol.102 , pp. 4824-4829
    • González, P.A.1    Carreño, L.J.2    Coombs, D.3    Mora, J.E.4    Palmieri, E.5
  • 164
    • 12444272793 scopus 로고    scopus 로고
    • Conduit for privileged communications in the lymph node
    • Anderson AO, Shaw S. 2005. Conduit for privileged communications in the lymph node. Immunity 22:3-5
    • (2005) Immunity , vol.22 , pp. 3-5
    • Anderson, A.O.1    Shaw, S.2
  • 165
    • 53149095854 scopus 로고    scopus 로고
    • Enhanced cellular activation with single walled carbon nanotube bundles presenting antibody stimuli
    • Fadel TR, Steenblock ER, Stern E, Li N,Wang X, et al. 2008. Enhanced cellular activation with single walled carbon nanotube bundles presenting antibody stimuli. Nano Lett. 8:2070-76
    • (2008) Nano Lett. , vol.8 , pp. 2070-2076
    • Fadel, T.R.1    Steenblock, E.R.2    Stern, E.3    Li, N.4    Wang, X.5
  • 166
    • 84874690008 scopus 로고    scopus 로고
    • Adsorption of multimeric T cell antigens on carbon nanotubes: Effect on protein structure and antigen-specific T cell stimulation
    • Fadel TR, Li N, Shah S, Look M, Pfefferle LD, et al. 2013. Adsorption of multimeric T cell antigens on carbon nanotubes: effect on protein structure and antigen-specific T cell stimulation. Small 9:666-72
    • (2013) Small , vol.9 , pp. 666-672
    • Fadel, T.R.1    Li, N.2    Shah, S.3    Look, M.4    Pfefferle, L.D.5
  • 167
    • 42249104403 scopus 로고    scopus 로고
    • Delivery of antigen using a novel mannosylated dendrimer potentiates immunogenicity in vitro and in vivo
    • Sheng K-C, Kalkanidis M, Pouniotis DS, Esparon S, Tang CK, et al. 2008. Delivery of antigen using a novel mannosylated dendrimer potentiates immunogenicity in vitro and in vivo. Eur. J. Immunol. 38:424-36
    • (2008) Eur. J. Immunol. , vol.38 , pp. 424-436
    • Sheng, K.-C.1    Kalkanidis, M.2    Pouniotis, D.S.3    Esparon, S.4    Tang, C.K.5
  • 169
    • 33947233339 scopus 로고    scopus 로고
    • A nanoscopic multivalent antigen-presenting carrier for sensitive detection and drug delivery to T cells
    • Fahmy TM, Schneck JP, Saltzman WM. 2007. A nanoscopic multivalent antigen-presenting carrier for sensitive detection and drug delivery to T cells. Nanomed. Nanotechnol. Biol. Med. 3:75-85
    • (2007) Nanomed. Nanotechnol. Biol. Med. , vol.3 , pp. 75-85
    • Fahmy, T.M.1    Schneck, J.P.2    Saltzman, W.M.3
  • 170
    • 82955237641 scopus 로고    scopus 로고
    • Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice
    • Zhou J, Neff CP, Liu X, Zhang J, Li H, et al. 2011. Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice. Mol. Ther. 19:2228-38
    • (2011) Mol. Ther. , vol.19 , pp. 2228-2238
    • Zhou, J.1    Neff, C.P.2    Liu, X.3    Zhang, J.4    Li, H.5
  • 171
    • 84867637264 scopus 로고    scopus 로고
    • Multivalent glycopeptide dendrimers for the targeted delivery of antigens to dendritic cells
    • Garcá-Vallejo JJ, Ambrosini M, Overbeek A, van RielWE, Bloem K, et al. 2013. Multivalent glycopeptide dendrimers for the targeted delivery of antigens to dendritic cells. Mol. Immunol. 53:387-97
    • (2013) Mol. Immunol. , vol.53 , pp. 387-397
    • Garcá-Vallejo, J.J.1    Ambrosini, M.2    Overbeek, A.3    Van Riel, W.E.4    Bloem, K.5
  • 172
    • 80053413863 scopus 로고    scopus 로고
    • An artificial antigen-presenting cell with paracrine delivery of IL-2 impacts the magnitude and direction of the T cell response
    • Steenblock ER, Fadel T, LabowskyM, Pober JS, Fahmy TM. 2011. An artificial antigen-presenting cell with paracrine delivery of IL-2 impacts the magnitude and direction of the T cell response. J. Biol. Chem. 286:34883-92
    • (2011) J. Biol. Chem. , vol.286 , pp. 34883-34892
    • Steenblock, E.R.1    Fadel, T.2    Labowsky, M.3    Pober, J.S.4    Fahmy, T.M.5
  • 173
    • 77951011799 scopus 로고    scopus 로고
    • Biomimetic approaches to modulating theTcell immune response with nano-And micro-particles
    • Demento S, Steenblock ER, FahmyTM. 2009. Biomimetic approaches to modulating theTcell immune response with nano-And micro-particles. Conf. Proc. IEEE Eng. Med. Biol. Soc. 2009:1161-66
    • (2009) Conf. Proc. IEEE Eng. Med. Biol. Soc. , vol.2009 , pp. 1161-1166
    • Demento, S.1    Steenblock, E.R.2    Fahmy, T.M.3
  • 174
    • 84891752647 scopus 로고    scopus 로고
    • Generation of functional, antigen-specific CD8+ human T cells from cord-blood stem cells using exogenous notch and tetramer-TCR signaling
    • Fernandez I, Ooi TP, Roy K. 2013. Generation of functional, antigen-specific CD8+ human T cells from cord-blood stem cells using exogenous notch and tetramer-TCR signaling. Stem Cell 32:93-104
    • (2013) Stem Cell , vol.32 , pp. 93-104
    • Fernandez, I.1    Ooi, T.P.2    Roy, K.3
  • 175
    • 77954932467 scopus 로고    scopus 로고
    • Programming dendritic cells to induceTH2 and tolerogenic responses
    • Pulendran B,TangH,Manicassamy S. 2010. Programming dendritic cells to induceTH2 and tolerogenic responses. Nat. Immunol. 11:647-55
    • (2010) Nat. Immunol. , vol.11 , pp. 647-655
    • Pulendran, B.1    Tang, H.2    Manicassamy, S.3
  • 176
    • 79956300649 scopus 로고    scopus 로고
    • Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
    • Kawai T, Akira S. 2011. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34:637-50
    • (2011) Immunity , vol.34 , pp. 637-650
    • Kawai, T.1    Akira, S.2
  • 177
    • 84866430987 scopus 로고    scopus 로고
    • Engagement of T-cell antigen receptor and CD4/CD8 co-receptors induces prolonged stat activation through autocrine/paracrine stimulation in human primary T cells
    • Chueh F-Y, Yu C-L. 2012. Engagement of T-cell antigen receptor and CD4/CD8 co-receptors induces prolonged stat activation through autocrine/paracrine stimulation in human primary T cells. Biochem. Biophys. Res. Commun. 426:242-46
    • (2012) Biochem. Biophys. Res. Commun. , vol.426 , pp. 242-246
    • Chueh, F.-Y.1    Yu, C.-L.2
  • 180
    • 84890335187 scopus 로고    scopus 로고
    • Carbon nanotube scaffolds instruct human dendritic cells: Modulating immune responses by contacts at the nanoscale
    • Aldinucci A, Turco A, Biagioli T, Toma FM, Bani D, et al. 2013. Carbon nanotube scaffolds instruct human dendritic cells: modulating immune responses by contacts at the nanoscale. Nano Lett. 13:6098-105
    • (2013) Nano Lett. , vol.13 , pp. 6098-6105
    • Aldinucci, A.1    Turco, A.2    Biagioli, T.3    Toma, F.M.4    Bani, D.5
  • 181
    • 84866995936 scopus 로고    scopus 로고
    • Substrate stiffness modulates gene expression and phenotype in neonatal cardiomyocytes in vitro
    • ForteG, Pagliari S, Ebara M, UtoK,Tam JKV, et al. 2012. Substrate stiffness modulates gene expression and phenotype in neonatal cardiomyocytes in vitro. Tissue Eng. Part A 18:1837-48
    • (2012) Tissue Eng. Part A , vol.18 , pp. 1837-1848
    • Forte, G.1    Pagliari, S.2    Ebara, M.3    Uto, K.4    Tam, J.K.V.5
  • 182
    • 10644233985 scopus 로고    scopus 로고
    • Gene expression clustering using self-organizing maps: Analysis of the macrophage response to particulate biomaterials
    • Garrigues GE, Cho DR, Rubash HE, Goldring SR, Herndon JH, Shanbhag AS. 2005. Gene expression clustering using self-organizing maps: Analysis of the macrophage response to particulate biomaterials. Biomaterials 26:2933-45
    • (2005) Biomaterials , vol.26 , pp. 2933-2945
    • Garrigues, G.E.1    Cho, D.R.2    Rubash, H.E.3    Goldring, S.R.4    Herndon, J.H.5    Shanbhag, A.S.6
  • 183
    • 77958588988 scopus 로고    scopus 로고
    • Gene expression study of monocytes/ macrophages during early foreign body reaction and identification of potential precursors of myofibroblasts
    • Mesure L, De VisscherG,Vranken I, Lebacq A, FlamengW. 2010. Gene expression study of monocytes/ macrophages during early foreign body reaction and identification of potential precursors of myofibroblasts. PLOS ONE 5:e12949
    • (2010) PLOS ONE , vol.5 , pp. e12949
    • Mesure, L.1    De Visscher, G.2    Vranken, I.3    Lebacq, A.4    Flameng, W.5
  • 184
    • 77955915569 scopus 로고    scopus 로고
    • Validation of a high-throughput methodology to assess the effects of biomaterials on dendritic cell phenotype
    • Kou PM, Babensee JE. 2010. Validation of a high-throughput methodology to assess the effects of biomaterials on dendritic cell phenotype. Acta Biomater. 6:2621-30
    • (2010) Acta Biomater. , vol.6 , pp. 2621-2630
    • Kou, P.M.1    Babensee, J.E.2
  • 185
    • 79251612605 scopus 로고    scopus 로고
    • Dendritic cell responses to surface properties of clinical titanium surfaces
    • Kou PM, Schwartz Z, Boyan BD, Babensee JE. 2011. Dendritic cell responses to surface properties of clinical titanium surfaces. Acta Biomater. 7:1354-63
    • (2011) Acta Biomater. , vol.7 , pp. 1354-1363
    • Kou, P.M.1    Schwartz, Z.2    Boyan, B.D.3    Babensee, J.E.4
  • 186
    • 83555177199 scopus 로고    scopus 로고
    • Predicting biomaterial property-dendritic cell phenotype relationships from the multivariate analysis of responses to polymethacrylates
    • Kou PM, Pallassana N, Bowden R, Cunningham B, Joy A, et al. 2012. Predicting biomaterial property-dendritic cell phenotype relationships from the multivariate analysis of responses to polymethacrylates. Biomaterials 33:1699-713
    • (2012) Biomaterials , vol.33 , pp. 1699-1713
    • Kou, P.M.1    Pallassana, N.2    Bowden, R.3    Cunningham, B.4    Joy, A.5
  • 187
  • 188
    • 77957291432 scopus 로고    scopus 로고
    • Polymer surface functionalities that control human embryoid body cell adhesion revealed by high throughput surface characterization of combinatorial material microarrays
    • Yang J, Mei Y, Hook AL, Taylor M, Urquhart AJ, et al. 2010. Polymer surface functionalities that control human embryoid body cell adhesion revealed by high throughput surface characterization of combinatorial material microarrays. Biomaterials 31:8827-38
    • (2010) Biomaterials , vol.31 , pp. 8827-8838
    • Yang, J.1    Mei, Y.2    Hook, A.L.3    Taylor, M.4    Urquhart, A.J.5
  • 189
    • 84862865591 scopus 로고    scopus 로고
    • Immunologically active biomaterials for cancer therapy
    • Ali OA, Mooney DJ. 2011. Immunologically active biomaterials for cancer therapy. Curr. Top. Microbiol. Immunol. 344:279-97
    • (2011) Curr. Top. Microbiol. Immunol. , vol.344 , pp. 279-297
    • Ali, O.A.1    Mooney, D.J.2
  • 190
    • 84864140479 scopus 로고    scopus 로고
    • Engineering nano-And microparticles to tune immunity
    • Moon JJ, Huang B, Irvine DJ. 2012. Engineering nano-And microparticles to tune immunity. Adv. Mater. 24:3724-46
    • (2012) Adv. Mater. , vol.24 , pp. 3724-3746
    • Moon, J.J.1    Huang, B.2    Irvine, D.J.3
  • 192
    • 84880626687 scopus 로고    scopus 로고
    • Integrative genomic analysis of the human immune response to influenza vaccination
    • Franco LM, Bucasas KL, Wells JM, Niño D, Wang X, et al. 2013. Integrative genomic analysis of the human immune response to influenza vaccination. eLife 2:e00299
    • (2013) ELife , vol.2 , pp. e00299
    • Franco, L.M.1    Bucasas, K.L.2    Wells, J.M.3    Niño, D.4    Wang, X.5
  • 193
    • 79953747554 scopus 로고    scopus 로고
    • Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity
    • Flach TL, Ng G, Hari A, Desrosiers MD, Zhang P, et al. 2011. Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity. Nat. Med. 17:479-87
    • (2011) Nat. Med. , vol.17 , pp. 479-487
    • Flach, T.L.1    Ng, G.2    Hari, A.3    Desrosiers, M.D.4    Zhang, P.5
  • 194
    • 80455154958 scopus 로고    scopus 로고
    • Alpha-Alumina nanoparticles induce efficient autophagy-dependent cross-presentation and potent antitumour response
    • Li H, Li Y, Jiao J, Hu HM. 2011. Alpha-Alumina nanoparticles induce efficient autophagy-dependent cross-presentation and potent antitumour response. Nat. Nanotechnol. 6:645-50
    • (2011) Nat. Nanotechnol. , vol.6 , pp. 645-650
    • Li, H.1    Li, Y.2    Jiao, J.3    Hu, H.M.4
  • 196
    • 79960299888 scopus 로고    scopus 로고
    • Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy
    • Rosenberg SA, Yang JC, Sherry RM,Kammula US,Hughes MS, et al. 2011. Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy. Clin. Cancer Res. 17:4550-57
    • (2011) Clin. Cancer Res. , vol.17 , pp. 4550-4557
    • Rosenberg, S.A.1    Yang, J.C.2    Sherry, R.M.3    Kammula, U.S.4    Hughes, M.S.5
  • 199
    • 84255197842 scopus 로고    scopus 로고
    • Cancer immunotherapy comes of age
    • Mellman I, Coukos G, Dranoff G. 2011. Cancer immunotherapy comes of age. Nature 480:480-89
    • (2011) Nature , vol.480 , pp. 480-489
    • Mellman, I.1    Coukos, G.2    Dranoff, G.3


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