An artificial antigen-presenting cell with paracrine delivery of IL-2 impacts the magnitude and direction of the T cell response

Journal of Biological Chemistry

Volumn 286, Issue 40, 2011, Pages 34883-34892

  Steenblock, Erin R ^a   Fadel, Tarek ^a   Labowsky, Michael ^b   Pober, Jordan S ^c   Fahmy, Tarek M ^a  

^a Yale University   (United States)

^b Ansama Research LLC   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION-INDUCED CELL DEATHS; ANTIGEN PRESENTING CELLS; COSTIMULATION; CYTOKINES; EMERGING TECHNOLOGIES; IN-VITRO; LOW LEVEL; PARACRINE; SUSTAINED RELEASE; SYNAPTIC CONTACTS; T CELLS; T-CELL RESPONSE; TEMPORAL CHARACTERISTICS;

BIODEGRADABLE POLYMERS; CELL DEATH;

ANTIGENS;

INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL ACTIVITY; CELL CONTACT; CELL COUNT; CELL DEATH; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RELEASE; IN VITRO STUDY; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; T LYMPHOCYTE;

ANIMALS; ANTIGEN PRESENTATION; ANTIGEN-PRESENTING CELLS; BIOCOMPATIBLE MATERIALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CYTOKINES; FLOW CYTOMETRY; INTERLEUKIN-2; MICE; MICE, INBRED C57BL; POLYMERS; T-LYMPHOCYTES;

EID: 80053413863     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.276329     Document Type: Article

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