Immune response to controlled release of immunomodulating peptides in a murine experimental autoimmune encephalomyelitis (EAE) model

Journal of Controlled Release

Volumn 141, Issue 2, 2010, Pages 145-152

  Zhao, Hong ^a   Kiptoo, Paul ^a   Williams, Todd D ^a   Siahaan, Teruna J ^a   Topp, Elizabeth M ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

EAE; Microparticles; PLP BPI peptides; Poly(D,L lactide)

Indexed keywords

ANTIGENIC PEPTIDES; BODY WEIGHT; CONTROLLED RELEASE; DOSING FREQUENCY; EAE; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; IMMUNE RESPONSE; MICRO-PARTICLES; MULTIPLE SCLEROSIS; OVERALL SURVIVAL; PLGA MICROPARTICLES; POLY (D ,L-LACTIDE); POLY-LACTIDE-CO-GLYCOLIDE; T CELL ACTIVATION; TREATMENT GROUP; WATER EMULSION;

AMINES; EMULSIFICATION; FLUORINE CONTAINING POLYMERS; IMMUNOLOGY; TOXICITY;

PEPTIDES;

ACETYL PROTEOLIPID PROTEIN BIFUNCTIONAL PEPTIDE INHIBITOR; IMMUNOMODULATING AGENT; POLYGLACTIN; PROTEOLIPID PROTEIN; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANAPHYLAXIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG EFFICACY; EVAPORATION; FEMALE; IMMUNE RESPONSE; IMMUNIZATION; IN VITRO STUDY; MORPHOLOGY; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; OVERALL SURVIVAL; PARTICLE SIZE; PRIORITY JOURNAL; SOLVENT EFFECT; SUPPRESSOR CELL; T LYMPHOCYTE ACTIVATION; TOXICITY TESTING;

ANAPHYLAXIS; ANIMALS; BODY WEIGHT; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; IMMUNOLOGIC FACTORS; INJECTIONS, INTRAVENOUS; INJECTIONS, SUBCUTANEOUS; LACTIC ACID; MICE; MYELIN PROTEOLIPID PROTEIN; PARTICLE SIZE; PEPTIDE FRAGMENTS; POLYGLYCOLIC ACID; SOLUBILITY; SURFACE PROPERTIES; TIME FACTORS;

EID: 72149128473     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.09.002     Document Type: Article

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