Nanoparticle conjugation of antigen enhances cytotoxic T-cell responses in pulmonary vaccination

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 44, 2011, Pages

  Nembrini, Chiara ^a   Stano, Armando ^a   Dane, Karen Y ^a   Ballester, Marie ^a   Van Der Vlies, André J ^a   Marsland, Benjamin J ^b,c   Swartz, Melody A ^a   Hubbell, Jeffrey A ^a  

^a EPFL   (Switzerland)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Adjuvant; Antigen conjugation; Antigen trafficking; Prophylactic; T lymphocyte

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; INFLUENZA VACCINE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; NANOPARTICLE; OVALBUMIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD8+ T LYMPHOCYTE; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DRUG DELIVERY SYSTEM; IMMUNIZATION; INFLUENZA A; INFLUENZA A (H1N1); LUNG; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH17 CELL; VACCINATION;

ANIMALS; ANTIGENS; CD8-POSITIVE T-LYMPHOCYTES; COCULTURE TECHNIQUES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNOLOGIC MEMORY; LUNG; LUNG DISEASES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NANOPARTICLES; T-LYMPHOCYTES, CYTOTOXIC; VACCINES;

MUS;

EID: 81055130325     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1104264108     Document Type: Article

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