Criteria impacting the cellular uptake of nanoparticles: A study emphasizing polymer type and surfactant effects

Acta Biomaterialia

Volumn 7, Issue 12, 2011, Pages 4160-4168

  Musyanovych, A ^a,b   Dausend, J ^b   Dass, M ^a,b   Walther, P ^b   Mailander V ^a,b,c   Landfester, K ^a,b  

^a MAX PLANCK INSTITUTE FOR POLYMER RESEARCH   (Germany)

^b UNIVERSITY OF ULM   (Germany)

^c UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

Electron microscopy; Flow cytometry; HeLa cells; Nanoparticle cell interaction; Surfactant

Indexed keywords

CATIONIC SURFACTANTS; CYTOLOGY; DYES; FLOW CYTOMETRY; FLUORESCENCE; FLUORESCENCE MICROSCOPY; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; LANTHANUM COMPOUNDS; SYNTHESIS (CHEMICAL);

CELL INTERACTION; CELLULAR UPTAKE; HELA CELL; NANOPARTICLE-CELL INTERACTION; NONIONIC; POLY (L-LACTIDE); POLYMER SURFACTANTS; POLYMER TYPES; SIZE RANGES; SURFACTANTS EFFECT;

NANOPARTICLES;

IONIC SURFACTANT; NANOPARTICLE; NONIONIC SURFACTANT; POLYLACTIDE; POLYSTYRENE;

ARTICLE; CELL TRANSPORT; CELL ULTRASTRUCTURE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HELA CELL; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; MOLECULAR STABILITY; NANOEMULSION; NANOFABRICATION; PARTICLE SIZE; PRIORITY JOURNAL; SURFACE CHARGE; TRANSMISSION ELECTRON MICROSCOPY;

EID: 80055102868     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2011.07.033     Document Type: Article

References (55)

1. D.F. Emerich, and C.G. Thanos Targeted nanoparticle-based drug delivery and diagnosis J Drug Target 15 2007 163 183 (Pubitemid 46562629)
2. G. Barratt Colloidal drug carriers: achievements and perspectives Cell Mol Life Sci 60 2003 21 37 (Pubitemid 36223115)
3. J. Panyam, and V. Labhasetwar Biodegradable nanoparticles for drug and gene delivery to cells and tissue Adv Drug Deliv Rev 55 2003 329 347 (Pubitemid 36297053)
4. D.B. Shenoy, J.S. Chawla, and M.M. Amiji Biodegradable polymeric nanoparticles for tumor-selective tamoxifen delivery: in vitro and in vivo studies Mat Res Soc Symp Proc 845 2005 369 373 (Pubitemid 40787973)
5. E. Allemann, J.C. Leroux, and R. Gurny Polymeric nano- and microparticles for the oral delivery of peptides and peptidomimetics Adv Drug Deliv Rev 34 1998 171 189 (Pubitemid 28535111)
6. S.M. Moghimi, A.C. Hunter, and J.C. Murray Nanomedicine: current status and future prospects FASEB J 19 2005 311 330 (Pubitemid 40316520)
7. M.S. Bhojani, M. Van Dort, A. Rehemtulla, and B.D. Ross Targeted imaging and therapy of brain cancer using theranostic nanoparticles Mol Pharmaceutics 7 2010 1921 1929
8. N.M. Khalil, and R.M. Mainardes Colloidal polymeric nanoparticles and brain drug delivery Curr Drug Deliv 6 2009 261 273
9. J.J. Lim, T.M. Hammoudi, A.M. Bratt-Leal, S.K. Hamilton, K.L. Kepple, and N.C. Bloodworth Development of nano- and microscale chondroitin sulfate particles for controlled growth factor delivery Acta Biomaterialia 7 2011 986 995
10. G. Sahay, D.Y. Alakhova, and A.V. Kabanov Endocytosis of nanomedicines J Control Release 145 2010 182 195
11. M. Murakami, H. Cabral, Y. Matsumoto, S. Wu, M.R. Kano, and T. Yamori Improving drug potency and efficacy by nanocarrier-mediated subcellular targeting Sci Transl Med 3 2011 64ra2
12. T. Musacchio, and V.P. Torchilin Recent developments in lipid-based pharmaceutical nanocarriers Front Biosci 1 2011 1388 1412
13. J.A. Champion, and S. Mitragotri Role of target geometry in phagocytosis Proc Nat Acad Sci USA. 103 2006 4930 4934
14. J.-W. Yoo, N. Doshi, and S. Mitragotri Endocytosis and intracellular distribution of PLGA particles in endothelial cells: effect of particle geometry Macromol Rapid Commun 31 2010 142 148
15. P. Decuzzi, B. Godin, T. Tanaka, S.-Y. Lee, C. Chiappini, and X. Liu Size and shape effects in the biodistribution of intravascularly injected particles J Control Release 141 2010 320 327
16. K. Makino, N. Yamamoto, K. Higuchi, N. Harada, H. Ohshima, and H. Terada Phagocytic uptake of polystyrene microspheres by alveolar macrophages: effects of the size and surface properties of the microspheres Colloid Surf B 27 2003 33 39 (Pubitemid 35346319)
17. C. Foged, B. Brodin, S. Frokjaer, and A. Sundblad Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model Int J Pharm 298 2005 315 322 (Pubitemid 40910735)
18. M.J. Heslinga, E.M. Mastria, and O. Eniola-Adefeso Fabrication of biodegradable spheroidal microparticles for drug delivery applications J Control Release 138 2009 235 242
19. S.E.A. Gratton, P.A. Ropp, P.D. Pohlhaus, J.C. Luft, V.J. Madden, and M.E. Napier The effect of particle design on cellular internalization pathways Proc Nat Acad Sci USA 105 2008 11613 11618
20. C.R. Miller, B. Bondurant, S.D. McLean, K.A. McGovern, and D.F. O'Brien Liposome-cell interactions in vitro: effect of liposome surface charge on the binding and endocytosis of conventional and sterically stabilized liposomes Biochemistry 37 1998 12875 12883 (Pubitemid 28433520)
21. C. Cortez, E. Tomaskovic-Crook, A.P.R. Johnston, A.M. Scott, E.C. Nice, and J.K. Heath Influence of size, surface, cell line, and kinetic properties on the specific binding of A33 antigen-targeted multilayered particles and capsules to colorectal cancer cells ACS Nano 1 2007 93 102
22. F. Alexis, E. Pridgen, L.K. Molnar, and O.C. Farokhzad Factors affecting the clearance and biodistribution of polymeric nanoparticles Mol Pharm 5 2008 505 515
23. L. Hu, Z. Mao, and C. Gao Colloidal particles for cellular uptake and delivery J Mater Chem 19 2009 3108 3115
24. W. Zauner, N.A. Farrow, and A.M.R. Haines In vitro uptake of polystyrene microspheres: effect of particle size, cell line and cell density J Control Release 71 2001 39 51 (Pubitemid 32195440)
25. K.Y. Win, and S.-S. Feng Effects of particle size and surface coating on cellular uptake of polymeric nanoparticles for oral delivery of anticancer drugs Biomaterials 26 2005 2713 2722 (Pubitemid 39600724)
26. P. Menei, A. Croue, V. Daniel, A. Pouplard-Barthelaix, and J.P. Benoit Fate and biocompatibility of three types of microspheres implanted into the brain J Biomed Mater Res 28 1994 1079 1085 (Pubitemid 24274850)
27. O. Benny, M. Duvshani-Eshet, T. Cargioli, L. Bello, A. Bikfalvi, and R.S. Carroll Continuous delivery of endogenous inhibitors from poly(lactic-co- glycolic acid) polymeric microspheres inhibits glioma tumor growth Clin Cancer Res 11 2005 768 776 (Pubitemid 40116906)
28. S. Duvvuri, K. Gaurav Janoria, and A.K. Mitra Effect of polymer blending on the release of ganciclovir from PLGA microspheres Pharm Res 23 2006 215 223 (Pubitemid 43214678)
29. M.K. Lai, and R.C.C. Tsiang Encapsulating acetaminophen into poly(l-lactide) microcapsules by solvent-evaporation technique in an O/W emulsion J Microencapsulation 21 2004 307 316
30. R.C. Mehta, R. Jeyanthi, S. Calis, B.C. Thanoo, K.W. Burton, and P.P. DeLuca Biodegradable microspheres as depot system for patenteral delivery of peptide drugs J Control Release 29 1994 375 384
31. J. Davda, and V. Labhasetwar Characterization of nanoparticle uptake by endothelial cells Int J Pharm 233 2002 51 59 (Pubitemid 34230418)
32. M.P. Desai, V. Labhasetwar, E. Walter, R.J. Levy, and G.L. Amidon The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent Pharm Res 14 1997 1568 1573 (Pubitemid 28009208)
33. J.H. Eldridge, C.J. Hammond, J.A. Meulbroek, J.K. Staas, R.M. Gilley, and T.R. Tice Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the peyer's patches J Control Release 11 1990 205 214 (Pubitemid 20070098)
34. P. Pietzonka, B. Rothen-Rutishauser, P. Langguth, H. Wunderli-Allenspach, E. Walter, and H.P. Merkle Transfer of lipophilic markers from PLGA and polystyrene nanoparticles to Caco-2 monolayers mimics particle uptake Pharm Res 19 2002 595 601 (Pubitemid 34553665)
35. A. Lamprecht, U. Schäfer, and C.M. Lehr Size-dependent bioadhesion of micro- and nanoparticulate carriers to the inflamed colonic mucosa Pharm Res 18 2001 788 793 (Pubitemid 32783514)
36. C. Wilhelm, C. Billotey, J. Roger, J.N. Pons, J.-C. Bacri, and F. Gazeau Intracellular uptake of anionic superparamagnetic nanoparticles as a function of their surface coating Biomaterials 24 2003 1001 1011 (Pubitemid 36024170)
37. C.K. Weiss, M.V. Kohnle, K. Landfester, T. Hauk, D. Fischer, and J. Schmitz-Wienke The first step into the brain: uptake of NIO-PBCA nanoparticles by endothelial cells in vitro and in vivo, and direct evidence for their blood-brain barrier permeation Chem Med Chem 3 2008 1395 1403
38. M.S. Cartiera, K.M. Johnson, V. Rajendran, M.J. Caplan, and W.M. Saltzman The uptake and intracellular fate of PLGA nanoparticles in epithelial cells Biomaterials 30 2009 2790 2798
39. S.W. Pang, H.Y. Park, Y.S. Jang, W.S. Kim, and J.H. Kim Effects of charge density and particle size of poly(styrene/(dimethylamino)ethyl methacrylate) nanoparticle for gene delivery in 293 cells Colloids Surf B: Biointerfaces 26 2002 213 222
40. B.C. Dash, G. Réthoré, M. Monaghan, K. Fitzgerald, W. Gallagher, and A. Pandit The influence of size and charge of chitosan/polyglutamic acid hollow spheres on cellular internalization, viability and blood compatibility Biomaterials 31 2010 8188 8197
41. X. Jiang, J. Dausend, M. Hafner, A. Musyanovych, C. Röcker, and K. Landfester Specific effects of surface amines on polystyrene nanoparticles in their interactions with mesenchymal stem cells Biomacromolecules 11 2010 748 753
42. J. Dausend, A. Musyanovych, M. Dass, P. Walther, H. Schrezenmeier, and K. Landfester Uptake mechanism of oppositely charged fluorescent nanoparticles in HeLa cells Macromol Biosci 8 2008 1135 1143
43. A. Musyanovych, R. Rossmanith, C. Tontsch, and K. Landfester Effect of hydrophilic comonomer and surfactant type on the colloidal stability and size distribution of carboxyl- and amino-functionalized polystyrene particles prepared by miniemulsion polymerization Langmuir 23 2007 5367 5376 (Pubitemid 46826482)
44. V. Holzapfel, A. Musyanovych, K. Landfester, M.R. Lorenz, and V. Mailander Preparation of fluorescent carboxyl and amino functionalized polystyrene particles by miniemulsion polymerization as markers for cells Macromol Chem Phys 206 2005 2440 2449 (Pubitemid 43051792)
45. A. Musyanovych, J. Schmitz-Wienke, V. Mailänder, P. Walther, and K. Landfester Preparation of biodegradable polymer nanoparticles by miniemulsion technique and their cell interactions Macromol Biosci 8 2008 127 139
46. Lagaly G, Schulz O, Zimehl R, Dispersionen und Emulsionen: eine Einführung in die Kolloidik feinverteilter Stoffe einschließlich der Tonminerale Steinkopff. Darmstadt: 1997.
47. B.R. Paulke, P.M. Moeglich, E. Knippel, A. Budde, R. Nitzsche, and R.H. Mueller Electrophoretic 3D-mobility profiles of latex particles with different surface groups Langmuir 11 1995 70 74
48. R.H. Müller Zetapotential und Partikelladung in der Laborpraxis: Einführung in die Theorie, praktische Messdurchführung, Dateninterpretation 1996 Wiss Verl-Ges Stuttgart
49. P. Walther, and A. Ziegler Freeze-substitution of high pressure frozen samples: the visibility of biological membranes is improved when the substitution medium contains water J Microsc 208 2002 3 10 (Pubitemid 35365577)
50. K. Landfester Synthesis of colloidal particles in miniemulsions Annu Rev Mater Res 36 2006 231 279 (Pubitemid 44476831)
51. K. Landfester Polyreactions in miniemulsions Macromol Rapid Commun 22 2001 896 936 (Pubitemid 33331727)
52. M.R. Lorenz, V. Holzapfel, A. Musyanovych, K. Nothelfer, P. Walther, and H. Frank Uptake of functionalized, fluorescent-labeled polymeric particles in different cell lines and stem cells Biomaterials 27 2006 2820 2828 (Pubitemid 43165751)
53. T. Xia, M. Kovochich, M. Liong, J.I. Zink, and A.E. Nel Cationic polystyrene nanosphere toxicity depends on cell-specific endocytic and mitochondrial injury pathways ACS Nano 2 2008 85 96 (Pubitemid 351595956)
54. H.H. Hohenberg, T. Müller-Reichert, H. Schwarz, and K. Zierold Foreword, special issue on high pressure freezing J Microsc 212 2003 1 2
55. J.S. Trent, J.I. Scheinbeim, and P.R. Couchman Ruthenium tetroxide staining of polymers for electron microscopy Macromolecules 16 1983 589 598