Modulating pharmacokinetics, tumor uptake and biodistribution by engineered nanoparticles

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Arvizo, Rochelle R ^a   Miranda, Oscar R ^b   Moyano, Daniel F ^b   Walden, Chad A ^c   Giri, Karuna ^a   Bhattacharya, Resham ^a   Robertson, J David ^d   Rotello, Vincent M ^b   Reid, Joel M ^c   Mukherjee, Priyabrata ^a,e  

^a MAYO GRADUATE SCHOOL   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

^c MAYO CLINIC ROCHESTER   (United States)

^d UNIVERSITY OF MISSOURI   (United States)

^e MAYO CLINIC CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GOLD NANOPARTICLE; GOLD; LIGAND; METAL NANOPARTICLE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG UPTAKE; MALE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; SOLID TUMOR; TIME TO MAXIMUM PLASMA CONCENTRATION; TUMOR XENOGRAFT; ANIMAL; CHEMISTRY; METABOLISM; NANOTECHNOLOGY; NEOPLASM; SURFACE PROPERTY; TIME; TISSUE DISTRIBUTION; TUMOR CELL LINE;

MUS;

ANIMALS; CELL LINE, TUMOR; GOLD; LIGANDS; MALE; METAL NANOPARTICLES; MICE; NANOTECHNOLOGY; NEOPLASMS; SURFACE PROPERTIES; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 80052699275     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024374     Document Type: Article

References (43)

1. Petros RA, DeSimone JM, (2010) Strategies in the design of nanoparticles for therapeutic applications. Nature Review Drug Discovery 9 (8): 615-627.
2. Davis AJ, Tannock IF, (2002) Tumor physiology and resistance to chemotherapy: repopulation and drug penetration. Cancer Treat Res 112: 1-26.
3. Gindy ME, Prud'homme RK, (2009) Multifunctional nanoparticles for imaging, delivery and targeting in cancer therapy. Expert Opinion on Drug Delivery 6 (8): 865-878.
4. Gao J, Liang G, Zhang B, Kuang Y, Zhang X, et al. (2007) FePt@CoS(2) yolk-shell nanocrystals as a potent agent to kill HeLa cells. J Am Chem Soc 129 (5): 1428-1433.
5. Langer R, Tirrell DA, (2004) Designing materials for biology and medicine. Nature 428 (6982): 487-492.
6. Chanda N, Kan P, Watkinson L, Shukla R, Zambre A, et al. (2010) Radioactive gold nanoparticles in cancer therapy: therapeutic efficacy studies of GA-198AuNP nanoconstruct in prostate tumor bearing mice. Nanomedicine: the official journal of the American Academy of Nanomedicine 6 (2): 201-209.
7. Wu W, Pastorin G, Benincasa M, Klumpp C, Briand J-P, et al. (2005) Targeted Delivery of Amphotericin B to Cells by Using Functionalized Carbon Nanotubes. Angewandte Chemie International Edition 44 (39): 6358-6362.
8. Sinha R, Kim GJ, Nie S, Shin DM, (2006) Nanotechnology in cancer therapeutics: bioconjugated nanoparticles for drug delivery. Mol Cancer Ther 5 (8): 1909-1917.
9. Katti K, Kannan R, Katti K, Kattumori V, Pandrapraganda R, et al. (2006) Hybrid gold nanoparticles in molecular imaging and radiotherapy. Czechoslovak Journal of Physics 56 (0): D23-D34.
10. Peer D, Karp JM, Hong S, Farokhzad OC, Margalit R, et al. (2007) Nanocarriers as an emerging platform for cancer therapy. Nat Nanotechnol 2 (12): 751-760 (in eng).
11. Mukherjee P, Bhattacharya R, Mukhopadhyay D, (2005) Gold Nanoparticles Bearing Functional Anti-Cancer Drug and Anti-Angiogenic Agent: A "2 in 1" System with Potential Application in Cancer Therapeutics. Journal of Biomedical Nanotechnology 1 (2): 224-228.
12. Jain RK, Stylianopoulos T, (2010) Delivering nanomedicine to solid tumors. Nat Rev Clin Oncol 7 (11): 653-664.
13. Choi HS, Liu W, Liu F, Nasr K, Misra P, et al. (2009) Design considerations for tumour-targeted nanoparticles. Nature Nanotechnology 5 (1): 42-47.
14. Perrault SD, Walkey C, Jennings T, Fischer HC, Chan WCW, (2009) Mediating Tumor Targeting Efficiency of Nanoparticles Through Design. Nano Letters 9 (5): 1909-1915.
15. Gwak H-S, Choi J-S, Choi H-K, (2005) Enhanced bioavailability of piroxicam via salt formation with ethanolamines. International Journal of Pharmaceutics 297 (1-2): 156-161.
16. Oh Y-K, Park TG, (2009) siRNA delivery systems for cancer treatment. Adv Drug Deliver Rev 61 pp. 850-862.
17. Hillyer JF, Albrecht RM, (2001) Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles. Journal of Pharmaceutical Sciences 90 (12): 1927-1936.
18. Hong R, Fernandez J, Nakade H, Arvizo R, Emrick T, et al. (2006) In situ observation of place exchange reactions of gold nanoparticles. Correlation of monolayer structure and stability. Chem Commun pp. 2347-2349.
19. Moyano DF, Rotello V, (2011) Nano Meets Biology: Structure and Function at the Nanoparticle Interface. Langmuir in press.
20. De M, Rana S, Akpinar H, Miranda OR, Arvizo RR, et al. (2009) Sensing of proteins in human serum using conjugates of nanoparticles and green fluorescent protein. Nature Chem 1 pp. 461-465.
21. Kim C-K, Ghosh P, Rotello VM, (2009) Multimodal Drug Delivery using Gold Nanoparticles. Nanoscale 1 pp. 61-67.
22. You CC, Miranda OR, Gider B., Ghosh P, (2007) Detection and identification of proteins using nanoparticle fluorescent polymer 'chemical nose' sensors. Nature Nanotechnology 2: 318-323.
23. Zhu ZJ, Ghosh PS, Miranda OR, Vachet RW, Rotello VM, (2008) Multiplexed Screening of Cellular Uptake of Gold Nanoparticles Using Laser Desorption/Ionization Mass Spectrometry. Journal of the American Chemical Society 130 (43): 14139-14143.
24. Agasti SS, Chompoosor A, You C-C, Ghosh P, Kim CK, et al. (2009) Photoregulated Release of Caged Anticancer Drugs from Gold Nanoparticles. Journal of the American Chemical Society 131 (16): 5728-5729.
25. Zhu Z-J CR, Quercio MJ, Yan B, Miranda OR, Anderton DL, et al. (2010) Surface properties dictate uptake, distribution, excretion, and toxicity of nanoparticles in fish. Small 6 pp. 2261-2265.
26. Fang JNH, Maeda H, (2011) The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv Drug Deliver Rev 63 pp. 136-151.
27. Li M, Al-Jamal KT, Kostarelos K, Reineke J, (2010) Physiologically Based Pharmacokinetic Modeling of Nanoparticles. ACS Nano 4 (11): 6303-6317.
28. Dobrovolskaia MA, McNeil SE, (2007) Immunological properties of engineered nanomaterials. 2 (8): 469-478.
29. Medintz IL, Uyeda HT, Goldman ER, Mattoussi H, (2005) Quantum dot bioconjugates for imaging, labelling and sensing. Nat Mater 4 (6): 435-446.
30. Grobmyer SR, Iwakuma N, Sharma P, Moudgil BM, (2010) Cancer Nanotechnology, Methods in Molecular Biology vol 624 pp. 1-9 (Springer, Heidelberg).
31. Moghimi SM, Bonnemain B, (1999) Subcutaneous and intravenous delivery of diagnostic agents to the lymphatic system: applications in lymphoscintigraphy and indirect lymphography. Advanced Drug Delivery Reviews 37 (1-3): 295-312.
32. Yang X-C, Samanta B, Agasti S, Jeong Y, Zhu ZJ, et al. (2009) Drug Delivery Using Nanoparticle-Stabilized Nanocapsules. Angewandte Chemie International Edition 50 (2): 477-481.
33. Ferrari M, (2005) Cancer nanotechnology: opportunities and challenges. Nat Rev Cancer 5 (3): 161-171.
34. Davis ME, Chen Z, Shin DM, (2008) Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat Rev Drug Discov 7 (9): 771-782.
35. Maltzahn G, Centrone A, Park JH, Ramanathan R, Sailor MJ, et al. (2009) SERS-Coded Gold Nanorods as a Multifunctional Platform for Densely Multiplexed Near-Infrared Imaging and Photothermal Heating. Advanced Materials 21 (31): 3175-3180.
36. Schluep T, Hwang J, Hildebrandt IJ, Czernin J, Choi CHJ, et al. (2009) Pharmacokinetics and tumor dynamics of the nanoparticle IT-101 from PET imaging and tumor histological measurements. Proceedings of the National Academy of Sciences 106 (27): 11394-11399.
37. Owens DE, Peppas NA, (2006) Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles. International Journal of Pharmaceutics 307 (1): 93-102.
38. Jain RK, (1990) Vascular and interstitial barriers to delivery of therapeutic agents in tumors. (Translated from eng) Cancer Metastasis Rev 9 (3): 253-266 (in eng).
39. Simberg D, Park JH, Karmali PP, Zhang WM, Merkulov S, et al. (2009) Differential proteomics analysis of the surface heterogeneity of dextran iron oxide nanoparticles and the implications for their in vivo clearance. Biomaterials 30 (23-24): 3926-3933.
40. Brust M, Walker M, Bethell D, Schiffrin DJ, Whyman RJ, (1994) Synthesis of Thiol-derivatised Gold Nanoparticles in a Two-phase Liquid-Liquid System. J Chem Soc Chem Commun pp. 801-802.
41. Kanaras AG, Kamounah FS, Schaumburg K, Kiely CJ, Brust M, (2002) Thioalkylated tetraethylene glycol: a new ligand for water soluble monolayer protected gold clusters. Chem Commun pp. 2294-2295.
42. Templeton AC, Wuelfing WP, Murray RW, (2000) Monolayer-Protected Cluster Molecules. Accounts of Chemical Research 33 (1): 27-36.
43. Arvizo RR, Miranda OR, Thompson MA, Pabelick CM, Bhattacharya R, et al. (2010) Effect of Nanoparticle Surface Charge at the Plasma Membrane and Beyond. Nano Letters 10 (7): 2543-2548.