Generation of effector memory T cell-based mucosal and systemic immunity with pulmonary nanoparticle vaccination

Science Translational Medicine

Volumn 5, Issue 204, 2013, Pages

  Li, Adrienne V ^a,b   Moon, James J ^a,c   Abraham, Wuhbet ^b   Suh, Heikyung ^b,d   Elkhader, Jamal ^a   Seidman, Michael A ^e   Yen, Minmin ^a   Im, Eung Jun ^b,f   Foley, Maria H ^a,b   Barouch, Dan H ^b,f   Irvine, Darrell J ^a,b,d  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA4BETA7 INTEGRIN; CD8 ANTIGEN; DIOLEOYLPHOSPHATIDYLCHOLINE; GAMMA INTERFERON; GRANZYME B; INTEGRIN; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 7 RECEPTOR; MACROGOL; NANOCAPSULE; NANOPARTICLE; OVALBUMIN; PHOSPHATIDYLETHANOLAMINE; PHOSPHORYL LIPID A; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL LIKE RECEPTOR AGONIST; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; ARTICLE; BRONCHITIS; CD8+ T LYMPHOCYTE; CELL COUNT; CELL VACUOLE; CONTROLLED STUDY; CROSS LINKING; CROSS PRESENTATION; DRUG DOSAGE FORM COMPARISON; DRUG SAFETY; DRUG TOLERABILITY; EFFECTOR CELL; FEMALE; IMMUNE RESPONSE; INTERSTITIAL PNEUMONIA; LAMELLAR BODY; LUNG GRANULOMA; LYMPHATIC DRAINAGE; LYMPHOCYTE HOMING; MEMORY T LYMPHOCYTE; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PHENOTYPE; PLEURISY; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY TRACT MUCOSA; T LYMPHOCYTE; VAGINA MUCOSA;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CROSS-PRIMING; DENDRITIC CELLS; IMMUNITY, MUCOSAL; IMMUNOLOGIC MEMORY; LUNG; LYMPH NODES; MICE; MICE, INBRED C57BL; MODELS, IMMUNOLOGICAL; NANOPARTICLES; T-LYMPHOCYTES; VACCINATION; VACCINIA VIRUS;

EID: 84884676871     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3006516     Document Type: Article

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