-
1
-
-
33846816853
-
Edward Jenner and the history of smallpox and vaccination
-
S. Riedel Edward Jenner and the history of smallpox and vaccination Proc (Bayl Univ Med Cent) 18 2005 21 25
-
(2005)
Proc (Bayl Univ Med Cent)
, vol.18
, pp. 21-25
-
-
Riedel, S.1
-
2
-
-
33846799128
-
Translational mini-review series on vaccines: The Edward Jenner Museum and the history of vaccination
-
A.J. Morgan, and S. Parker Translational mini-review series on vaccines: The Edward Jenner Museum and the history of vaccination Clin Exp Immunol 147 2007 389 394
-
(2007)
Clin Exp Immunol
, vol.147
, pp. 389-394
-
-
Morgan, A.J.1
Parker, S.2
-
3
-
-
7044263390
-
Vaccine adjuvants: Current state and future trends
-
N. Petrovsky, and J.C. Aguilar Vaccine adjuvants: Current state and future trends Immunol Cell Biol 82 2004 488 496
-
(2004)
Immunol Cell Biol
, vol.82
, pp. 488-496
-
-
Petrovsky, N.1
Aguilar, J.C.2
-
4
-
-
84879931604
-
Unconventional vaccines: Progress and challenges
-
N. Petrovsky Unconventional vaccines: Progress and challenges J Vaccines Vaccin 4 2013 186
-
(2013)
J Vaccines Vaccin
, vol.4
, pp. 186
-
-
Petrovsky, N.1
-
6
-
-
0035967233
-
The effectiveness of the varicella vaccine in clinical practice
-
M. Vazquez, P.S. LaRussa, A.A. Gershon, S.P. Steinberg, K. Freudigman, and E.D. Shapiro The effectiveness of the varicella vaccine in clinical practice N Engl J Med 344 2001 955 960
-
(2001)
N Engl J Med
, vol.344
, pp. 955-960
-
-
Vazquez, M.1
LaRussa, P.S.2
Gershon, A.A.3
Steinberg, S.P.4
Freudigman, K.5
Shapiro, E.D.6
-
7
-
-
21144448596
-
A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults
-
M.N. Oxman, M.J. Levin, G.R. Johnson, K.E. Schmader, S.E. Straus, L.D. Gelb, and et al. A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults N Engl J Med 352 2005 2271 2284
-
(2005)
N Engl J Med
, vol.352
, pp. 2271-2284
-
-
Oxman, M.N.1
Levin, M.J.2
Johnson, G.R.3
Schmader, K.E.4
Straus, S.E.5
Gelb, L.D.6
-
10
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
P.W. Kantoff, C.S. Higano, N.D. Shore, E.R. Berger, E.J. Small, D.F. Penson, and et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer N Engl J Med 363 2010 411 422
-
(2010)
N Engl J Med
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
Berger, E.R.4
Small, E.J.5
Penson, D.F.6
-
12
-
-
84921345093
-
Antibodies to watch in 2015
-
J.M. Reichert Antibodies to watch in 2015 MAbs 7 2015 1 8
-
(2015)
MAbs
, vol.7
, pp. 1-8
-
-
Reichert, J.M.1
-
13
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
J. Hardy, and D.J. Selkoe The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics Science 297 2002 353 356
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
14
-
-
0026597063
-
Alzheimer's disease: the amyloid cascade hypothesis
-
J.A. Hardy, and G.A. Higgins Alzheimer's disease: the amyloid cascade hypothesis Science 256 1992 184 185
-
(1992)
Science
, vol.256
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, G.A.2
-
15
-
-
84872559990
-
Molecular mechanisms of amyloid oligomers toxicity
-
R. Kayed, and C.A. Lasagna-Reeves Molecular mechanisms of amyloid oligomers toxicity J Alzheimers Dis 33 Suppl 1 2013 S67 S78
-
(2013)
J Alzheimers Dis
, vol.33
, pp. S67-S78
-
-
Kayed, R.1
Lasagna-Reeves, C.A.2
-
16
-
-
45249108473
-
Structure-function implications in Alzheimer's disease: Effect of Abeta oligomers at central synapses
-
W. Cerpa, M.C. Dinamarca, and N.C. Inestrosa Structure-function implications in Alzheimer's disease: Effect of Abeta oligomers at central synapses Curr Alzheimer Res 5 2008 233 243
-
(2008)
Curr Alzheimer Res
, vol.5
, pp. 233-243
-
-
Cerpa, W.1
Dinamarca, M.C.2
Inestrosa, N.C.3
-
18
-
-
76649129325
-
Alzheimer Abeta peptide induces chromosome mis-segregation and aneuploidy, including trisomy 21: Requirement for tau and APP
-
A. Granic, J. Padmanabhan, M. Norden, and H. Potter Alzheimer Abeta peptide induces chromosome mis-segregation and aneuploidy, including trisomy 21: Requirement for tau and APP Mol Biol Cell 21 2010 511 520
-
(2010)
Mol Biol Cell
, vol.21
, pp. 511-520
-
-
Granic, A.1
Padmanabhan, J.2
Norden, M.3
Potter, H.4
-
19
-
-
0025801967
-
Review and hypothesis: Alzheimer disease and Down syndrome - chromosome 21 nondisjunction may underlie both disorders
-
H. Potter Review and hypothesis: Alzheimer disease and Down syndrome - chromosome 21 nondisjunction may underlie both disorders Am J Hum Genet 48 1991 1192 1200
-
(1991)
Am J Hum Genet
, vol.48
, pp. 1192-1200
-
-
Potter, H.1
-
20
-
-
21044453723
-
Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo
-
I. Klyubin, D.M. Walsh, C.A. Lemere, W.K. Cullen, G.M. Shankar, V. Betts, and et al. Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo Nat Med 11 2005 556 561
-
(2005)
Nat Med
, vol.11
, pp. 556-561
-
-
Klyubin, I.1
Walsh, D.M.2
Lemere, C.A.3
Cullen, W.K.4
Shankar, G.M.5
Betts, V.6
-
21
-
-
84858195896
-
New pharmacological strategies for treatment of Alzheimer's disease: Focus on disease modifying drugs
-
S. Salomone, F. Caraci, G.M. Leggio, J. Fedotova, and F. Drago New pharmacological strategies for treatment of Alzheimer's disease: Focus on disease modifying drugs Br J Clin Pharmacol 73 2012 504 517
-
(2012)
Br J Clin Pharmacol
, vol.73
, pp. 504-517
-
-
Salomone, S.1
Caraci, F.2
Leggio, G.M.3
Fedotova, J.4
Drago, F.5
-
22
-
-
79955671043
-
Targeting oligomers in neurodegenerative disorders: Lessons from alpha-synuclein, tau, and amyloid-beta peptide
-
B.S. Gadad, G.B. Britton, and K.S. Rao Targeting oligomers in neurodegenerative disorders: Lessons from alpha-synuclein, tau, and amyloid-beta peptide J Alzheimers Dis 24 Suppl 2 2011 223 232
-
(2011)
J Alzheimers Dis
, vol.24
, pp. 223-232
-
-
Gadad, B.S.1
Britton, G.B.2
Rao, K.S.3
-
23
-
-
0033536163
-
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
see comments
-
D. Schenk, R. Barbour, W. Dunn, G. Gordon, H. Grajeda, T. Guido, and et al. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse [see comments] Nature 400 1999 173 177
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guido, T.6
-
24
-
-
4444362840
-
Current progress in beta-amyloid immunotherapy
-
D. Schenk, M. Hagen, and P. Seubert Current progress in beta-amyloid immunotherapy Curr Opin Immunol 16 2004 599 606
-
(2004)
Curr Opin Immunol
, vol.16
, pp. 599-606
-
-
Schenk, D.1
Hagen, M.2
Seubert, P.3
-
25
-
-
84984755327
-
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
-
D. Morgan, D.M. Diamond, P.E. Gottschall, K.E. Ugen, C. Dickey, J. Hardy, and et al. A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease Nature 408 2000 982 985
-
(2000)
Nature
, vol.408
, pp. 982-985
-
-
Morgan, D.1
Diamond, D.M.2
Gottschall, P.E.3
Ugen, K.E.4
Dickey, C.5
Hardy, J.6
-
27
-
-
0034700480
-
A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease
-
G. Chen, K.S. Chen, J. Knox, J. Inglis, A. Bernard, S.J. Martin, and et al. A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease Nature 408 2000 975 979
-
(2000)
Nature
, vol.408
, pp. 975-979
-
-
Chen, G.1
Chen, K.S.2
Knox, J.3
Inglis, J.4
Bernard, A.5
Martin, S.J.6
-
28
-
-
0033835996
-
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
-
F. Bard, C. Cannon, R. Barbour, R.L. Burke, D. Games, H. Grajeda, and et al. Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease Nat Med 6 2000 916 919
-
(2000)
Nat Med
, vol.6
, pp. 916-919
-
-
Bard, F.1
Cannon, C.2
Barbour, R.3
Burke, R.L.4
Games, D.5
Grajeda, H.6
-
29
-
-
0035902619
-
Peripheral anti-Abeta antibody alters CNS and plasma Abeta clearance and decreases brain Abeta burden in a mouse model of Alzheimer's disease
-
R.B. DeMattos, K.R. Bales, D.J. Cummins, J.C. Dodart, S.M. Paul, and D.M. Holtzman Peripheral anti-Abeta antibody alters CNS and plasma Abeta clearance and decreases brain Abeta burden in a mouse model of Alzheimer's disease Proc Natl Acad Sci U S A 98 2001 8850 8855
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 8850-8855
-
-
DeMattos, R.B.1
Bales, K.R.2
Cummins, D.J.3
Dodart, J.C.4
Paul, S.M.5
Holtzman, D.M.6
-
30
-
-
0036240395
-
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model
-
J.C. Dodart, K.R. Bales, K.S. Gannon, S.J. Greene, R.B. DeMattos, C. Mathis, and et al. Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model Nat Neurosci 5 2002 452 457
-
(2002)
Nat Neurosci
, vol.5
, pp. 452-457
-
-
Dodart, J.C.1
Bales, K.R.2
Gannon, K.S.3
Greene, S.J.4
DeMattos, R.B.5
Mathis, C.6
-
31
-
-
14244255355
-
Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage
-
D.M. Wilcock, A. Rojiani, A. Rosenthal, S. Subbarao, M.J. Freeman, M.N. Gordon, and et al. Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage J Neuroinflammation 1 2004 24
-
(2004)
J Neuroinflammation
, vol.1
, pp. 24
-
-
Wilcock, D.M.1
Rojiani, A.2
Rosenthal, A.3
Subbarao, S.4
Freeman, M.J.5
Gordon, M.N.6
-
32
-
-
0037452779
-
Epitope and isotype specificities of antibodies to beta-amyloid peptide for protection against Alzheimer's disease-like neuropathology
-
F. Bard, R. Barbour, C. Cannon, R. Carretto, M. Fox, D. Games, and et al. Epitope and isotype specificities of antibodies to beta-amyloid peptide for protection against Alzheimer's disease-like neuropathology Proc Natl Acad Sci U S A 100 2003 2023 2028
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 2023-2028
-
-
Bard, F.1
Barbour, R.2
Cannon, C.3
Carretto, R.4
Fox, M.5
Games, D.6
-
33
-
-
0035106780
-
Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy
-
B.J. Bacskai, S.T. Kajdasz, R.H. Christie, C. Carter, D. Games, P. Seubert, and et al. Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy Nat Med 7 2001 369 372
-
(2001)
Nat Med
, vol.7
, pp. 369-372
-
-
Bacskai, B.J.1
Kajdasz, S.T.2
Christie, R.H.3
Carter, C.4
Games, D.5
Seubert, P.6
-
34
-
-
1642497601
-
Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration
-
D.M. Wilcock, S.K. Munireddy, A. Rosenthal, K.E. Ugen, M.N. Gordon, and D. Morgan Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration Neurobiol Dis 15 2004 11 20
-
(2004)
Neurobiol Dis
, vol.15
, pp. 11-20
-
-
Wilcock, D.M.1
Munireddy, S.K.2
Rosenthal, A.3
Ugen, K.E.4
Gordon, M.N.5
Morgan, D.6
-
36
-
-
0032145617
-
N-terminal EFRH sequence of Alzheimer's beta-amyloid peptide represents the epitope of its anti-aggregating antibodies
-
D. Frenkel, M. Balass, and B. Solomon N-terminal EFRH sequence of Alzheimer's beta-amyloid peptide represents the epitope of its anti-aggregating antibodies J Neuroimmunol 88 1998 85 90
-
(1998)
J Neuroimmunol
, vol.88
, pp. 85-90
-
-
Frenkel, D.1
Balass, M.2
Solomon, B.3
-
37
-
-
0033103657
-
High affinity binding of monoclonal antibodies to the sequential epitope EFRH of beta-amyloid peptide is essential for modulation of fibrillar aggregation
-
D. Frenkel, M. Balass, E. Katchalski-Katzir, and B. Solomon High affinity binding of monoclonal antibodies to the sequential epitope EFRH of beta-amyloid peptide is essential for modulation of fibrillar aggregation J Neuroimmunol 95 1999 136 142
-
(1999)
J Neuroimmunol
, vol.95
, pp. 136-142
-
-
Frenkel, D.1
Balass, M.2
Katchalski-Katzir, E.3
Solomon, B.4
-
38
-
-
0037107177
-
Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy
-
B.J. Bacskai, S.T. Kajdasz, M.E. McLellan, D. Games, P. Seubert, D. Schenk, and et al. Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy J Neurosci 22 2002 7873 7878
-
(2002)
J Neurosci
, vol.22
, pp. 7873-7878
-
-
Bacskai, B.J.1
Kajdasz, S.T.2
McLellan, M.E.3
Games, D.4
Seubert, P.5
Schenk, D.6
-
39
-
-
0037155581
-
Brain to plasma amyloid-beta efflux: A measure of brain amyloid burden in a mouse model of Alzheimer's disease
-
R.B. DeMattos, K.R. Bales, D.J. Cummins, S.M. Paul, and D.M. Holtzman Brain to plasma amyloid-beta efflux: A measure of brain amyloid burden in a mouse model of Alzheimer's disease Science 295 2002 2264 2267
-
(2002)
Science
, vol.295
, pp. 2264-2267
-
-
DeMattos, R.B.1
Bales, K.R.2
Cummins, D.J.3
Paul, S.M.4
Holtzman, D.M.5
-
40
-
-
0036319503
-
Plaque-associated disruption of CSF and plasma amyloid-b (Ab) equilibrium in a mouse model of Alzheimer's disease
-
R.B. DeMattos, K.R. Bales, M. Parsadanian, M.A. O'Dell, E.M. Foss, S.M. Paul, and et al. Plaque-associated disruption of CSF and plasma amyloid-b (Ab) equilibrium in a mouse model of Alzheimer's disease J Neurochem 81 2002 229 236
-
(2002)
J Neurochem
, vol.81
, pp. 229-236
-
-
DeMattos, R.B.1
Bales, K.R.2
Parsadanian, M.3
O'Dell, M.A.4
Foss, E.M.5
Paul, S.M.6
-
42
-
-
84856479445
-
Targeting beta amyloid: A clinical review of immunotherapeutic approaches in Alzheimer's disease
-
K. Lobello, J.M. Ryan, E. Liu, G. Rippon, and R. Black Targeting beta amyloid: A clinical review of immunotherapeutic approaches in Alzheimer's disease Int J Alzheimers Dis 2012 2012 628070
-
(2012)
Int J Alzheimers Dis
, vol.2012
, pp. 628070
-
-
Lobello, K.1
Ryan, J.M.2
Liu, E.3
Rippon, G.4
Black, R.5
-
43
-
-
84895729926
-
Amyloid-β-directed immunotherapy for Alzheimer's disease
-
L. Lannfelt, N.R. Relkin, and E.R. Siemers Amyloid-β-directed immunotherapy for Alzheimer's disease J Intern Med 275 2014 284 295
-
(2014)
J Intern Med
, vol.275
, pp. 284-295
-
-
Lannfelt, L.1
Relkin, N.R.2
Siemers, E.R.3
-
44
-
-
84655160770
-
'Clinical trials in Alzheimer's disease': Immunotherapy approaches
-
J. Delrieu, P.J. Ousset, C. Caillaud, and B. Vellas 'Clinical trials in Alzheimer's disease': Immunotherapy approaches J Neurochem 120 Suppl 1 2012 186 193
-
(2012)
J Neurochem
, vol.120
, pp. 186-193
-
-
Delrieu, J.1
Ousset, P.J.2
Caillaud, C.3
Vellas, B.4
-
45
-
-
76849091134
-
Can Alzheimer disease be prevented by amyloid-beta immunotherapy?
-
C.A. Lemere, and E. Masliah Can Alzheimer disease be prevented by amyloid-beta immunotherapy? Nat Rev Neurol 6 2010 108 119
-
(2010)
Nat Rev Neurol
, vol.6
, pp. 108-119
-
-
Lemere, C.A.1
Masliah, E.2
-
47
-
-
84918796063
-
Active and passive Aβ-immunotherapy: Positive and negative outcomes from pre-clinical and clinical trials and future directions
-
M.G. Agadjanyan, and D. Cribbs Active and passive Aβ-immunotherapy: Positive and negative outcomes from pre-clinical and clinical trials and future directions CNS Neurol Disord Drug Targets 8 1 & 2 2009
-
(2009)
CNS Neurol Disord Drug Targets
, vol.8
, Issue.1-2
-
-
Agadjanyan, M.G.1
Cribbs, D.2
-
48
-
-
67649662393
-
AD vaccines: Conclusions and future directions
-
T. Wisniewski AD vaccines: Conclusions and future directions CNS Neurol Disord Drug Targets 8 2009 160 166
-
(2009)
CNS Neurol Disord Drug Targets
, vol.8
, pp. 160-166
-
-
Wisniewski, T.1
-
49
-
-
84897954317
-
Immunotherapy for Alzheimer's disease
-
T. Wisniewski, and F. Goni Immunotherapy for Alzheimer's disease Biochem Pharmacol 88 2014 499 507
-
(2014)
Biochem Pharmacol
, vol.88
, pp. 499-507
-
-
Wisniewski, T.1
Goni, F.2
-
50
-
-
84945491518
-
Biogen antibody buoyed by phase 1 data and hungry investors
-
Presented at the, March 25, 2015
-
Alzforum Biogen antibody buoyed by phase 1 data and hungry investors 2015 Presented at the AD/PD Conference, March 25, 2015
-
(2015)
AD/PD Conference
-
-
-
51
-
-
84945438329
-
Aducanumab (BIIB037) reduced brain amyloid plaque levels and slowed cognitive decline in patients with prodromal or mild Alzheimer's disease in phase 1B study
-
Neurimmune. Aducanumab (BIIB037) reduced brain amyloid plaque levels and slowed cognitive decline in patients with prodromal or mild Alzheimer's disease in phase 1B study. Biogen Idec presents positive interim results from phase 1B study at 2015 AD/PD Conference 2015.
-
(2015)
Biogen Idec presents positive interim results from phase 1B study at 2015 AD/PD Conference
-
-
Neurimmune1
-
52
-
-
0037393454
-
Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: A case report
-
J.A. Nicoll, D. Wilkinson, C. Holmes, P. Steart, H. Markham, and R.O. Weller Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: A case report Nat Med 9 2003 448 452
-
(2003)
Nat Med
, vol.9
, pp. 448-452
-
-
Nicoll, J.A.1
Wilkinson, D.2
Holmes, C.3
Steart, P.4
Markham, H.5
Weller, R.O.6
-
53
-
-
10744230547
-
Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization
-
J.M. Orgogozo, S. Gilman, J.M. Dartigues, B. Laurent, M. Puel, L.C. Kirby, and et al. Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization Neurology 61 2003 46 54
-
(2003)
Neurology
, vol.61
, pp. 46-54
-
-
Orgogozo, J.M.1
Gilman, S.2
Dartigues, J.M.3
Laurent, B.4
Puel, M.5
Kirby, L.C.6
-
54
-
-
1042265187
-
Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease
-
I. Ferrer, M.B. Rovira, M.L. Guerra, M.J. Rey, and F. Costa-Jussa Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease Brain Pathol 14 2004 11 20
-
(2004)
Brain Pathol
, vol.14
, pp. 11-20
-
-
Ferrer, I.1
Rovira, M.B.2
Guerra, M.L.3
Rey, M.J.4
Costa-Jussa, F.5
-
55
-
-
19944429065
-
Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease
-
E. Masliah, L. Hansen, A. Adame, L. Crews, F. Bard, C. Lee, and et al. Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease Neurology 64 2005 129 131
-
(2005)
Neurology
, vol.64
, pp. 129-131
-
-
Masliah, E.1
Hansen, L.2
Adame, A.3
Crews, L.4
Bard, F.5
Lee, C.6
-
56
-
-
33750586141
-
Abeta species removal after abeta42 immunization
-
J.A. Nicoll, E. Barton, D. Boche, J.W. Neal, I. Ferrer, P. Thompson, and et al. Abeta species removal after abeta42 immunization J Neuropathol Exp Neurol 65 2006 1040 1048
-
(2006)
J Neuropathol Exp Neurol
, vol.65
, pp. 1040-1048
-
-
Nicoll, J.A.1
Barton, E.2
Boche, D.3
Neal, J.W.4
Ferrer, I.5
Thompson, P.6
-
57
-
-
33748767945
-
Amyloid-beta peptide remnants in AN-1792-immunized Alzheimer's disease patients: A biochemical analysis
-
R.L. Patton, W.M. Kalback, C.L. Esh, T.A. Kokjohn, G.D. Van Vickle, D.C. Luehrs, and et al. Amyloid-beta peptide remnants in AN-1792-immunized Alzheimer's disease patients: A biochemical analysis Am J Pathol 169 2006 1048 1063
-
(2006)
Am J Pathol
, vol.169
, pp. 1048-1063
-
-
Patton, R.L.1
Kalback, W.M.2
Esh, C.L.3
Kokjohn, T.A.4
Van Vickle, G.D.5
Luehrs, D.C.6
-
58
-
-
20944448555
-
Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial
-
S. Gilman, M. Koller, R.S. Black, L. Jenkins, S.G. Griffith, N.C. Fox, and et al. Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial Neurology 64 2005 1553 1562
-
(2005)
Neurology
, vol.64
, pp. 1553-1562
-
-
Gilman, S.1
Koller, M.2
Black, R.S.3
Jenkins, L.4
Griffith, S.G.5
Fox, N.C.6
-
60
-
-
84901436269
-
History of narcolepsy at Stanford University
-
E.J. Mignot History of narcolepsy at Stanford University Immunol Res 58 2014 315 339
-
(2014)
Immunol Res
, vol.58
, pp. 315-339
-
-
Mignot, E.J.1
-
61
-
-
84899102996
-
Narcolepsy, 2009 A(H1N1) pandemic influenza, and pandemic influenza vaccinations: What is known and unknown about the neurological disorder, the role for autoimmunity, and vaccine adjuvants
-
S.S. Ahmed, P.H. Schur, N.E. MacDonald, and L. Steinman Narcolepsy, 2009 A(H1N1) pandemic influenza, and pandemic influenza vaccinations: What is known and unknown about the neurological disorder, the role for autoimmunity, and vaccine adjuvants J Autoimmun 50 2014 1 11
-
(2014)
J Autoimmun
, vol.50
, pp. 1-11
-
-
Ahmed, S.S.1
Schur, P.H.2
MacDonald, N.E.3
Steinman, L.4
-
62
-
-
79960827514
-
Explorations of clinical trials and pharmacovigilance databases of MF59(R)-adjuvanted influenza vaccines for associated cases of narcolepsy
-
T.F. Tsai, A. Crucitti, P. Nacci, U. Nicolay, G. Della Cioppa, J. Ferguson, and et al. Explorations of clinical trials and pharmacovigilance databases of MF59(R)-adjuvanted influenza vaccines for associated cases of narcolepsy Scand J Infect Dis 43 2011 702 706
-
(2011)
Scand J Infect Dis
, vol.43
, pp. 702-706
-
-
Tsai, T.F.1
Crucitti, A.2
Nacci, P.3
Nicolay, U.4
Della Cioppa, G.5
Ferguson, J.6
-
63
-
-
84945197664
-
Comparative safety of vaccine adjuvants: a summary of current evidence and future needs
-
In Press
-
N. Petrovsky Comparative safety of vaccine adjuvants: a summary of current evidence and future needs Drug Saf 2015 In Press
-
(2015)
Drug Saf
-
-
Petrovsky, N.1
-
64
-
-
11444267243
-
Evaluation of the safety and immunogenicity of synthetic Abeta42 (AN1792) in patients with AD
-
A.J. Bayer, R. Bullock, R.W. Jones, D. Wilkinson, K.R. Paterson, L. Jenkins, and et al. Evaluation of the safety and immunogenicity of synthetic Abeta42 (AN1792) in patients with AD Neurology 64 2005 94 101
-
(2005)
Neurology
, vol.64
, pp. 94-101
-
-
Bayer, A.J.1
Bullock, R.2
Jones, R.W.3
Wilkinson, D.4
Paterson, K.R.5
Jenkins, L.6
-
65
-
-
18144415471
-
Effects of Abeta immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease
-
N.C. Fox, R.S. Black, S. Gilman, M.N. Rossor, S.G. Griffith, L. Jenkins, and et al. Effects of Abeta immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease Neurology 64 2005 1563 1572
-
(2005)
Neurology
, vol.64
, pp. 1563-1572
-
-
Fox, N.C.1
Black, R.S.2
Gilman, S.3
Rossor, M.N.4
Griffith, S.G.5
Jenkins, L.6
-
66
-
-
0036853548
-
Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease
-
C. Hock, U. Konietzko, A. Papassotiropoulos, A. Wollmer, J. Streffer, R.C. Von Rotz, and et al. Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease Nat Med 8 2002 1270 1275
-
(2002)
Nat Med
, vol.8
, pp. 1270-1275
-
-
Hock, C.1
Konietzko, U.2
Papassotiropoulos, A.3
Wollmer, A.4
Streffer, J.5
Von Rotz, R.C.6
-
67
-
-
47149112621
-
Long-term effects of Abeta42 immunization in Alzheimer's disease: Follow-up of a randomised, placebo-controlled phase I trial
-
C. Holmes, D. Boche, D. Wilkinson, G. Yadegarfar, V. Hopkins, A. Bayer, and et al. Long-term effects of Abeta42 immunization in Alzheimer's disease: Follow-up of a randomised, placebo-controlled phase I trial Lancet 372 2008 216 223
-
(2008)
Lancet
, vol.372
, pp. 216-223
-
-
Holmes, C.1
Boche, D.2
Wilkinson, D.3
Yadegarfar, G.4
Hopkins, V.5
Bayer, A.6
-
68
-
-
0038100154
-
Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease
-
C. Hock, U. Konietzko, J.R. Streffer, J. Tracy, A. Signorell, B. Muller-Tillmanns, and et al. Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease Neuron 38 2003 547 554
-
(2003)
Neuron
, vol.38
, pp. 547-554
-
-
Hock, C.1
Konietzko, U.2
Streffer, J.R.3
Tracy, J.4
Signorell, A.5
Muller-Tillmanns, B.6
-
69
-
-
0032502801
-
Homeostasis and self-tolerance in the immune system: Turning lymphocytes off
-
L. Van Parijs, and A.K. Abbas Homeostasis and self-tolerance in the immune system: Turning lymphocytes off Science 280 1998 243 248
-
(1998)
Science
, vol.280
, pp. 243-248
-
-
Van Parijs, L.1
Abbas, A.K.2
-
71
-
-
67649635733
-
Critical issues for successful immunotherapy in Alzheimer's disease: Development of biomarkers and methods for early detection and intervention
-
R. Tarawneh, and D.M. Holtzman Critical issues for successful immunotherapy in Alzheimer's disease: Development of biomarkers and methods for early detection and intervention CNS Neurol Disord Drug Targets 8 2009 144 159
-
(2009)
CNS Neurol Disord Drug Targets
, vol.8
, pp. 144-159
-
-
Tarawneh, R.1
Holtzman, D.M.2
-
72
-
-
67049101507
-
Antibody responses, amyloid-beta peptide remnants and clinical effects of AN-1792 immunization in patients with AD in an interrupted trial
-
T.A. Kokjohn, and A.E. Roher Antibody responses, amyloid-beta peptide remnants and clinical effects of AN-1792 immunization in patients with AD in an interrupted trial CNS Neurol Disord Drug Targets 8 2009 88 97
-
(2009)
CNS Neurol Disord Drug Targets
, vol.8
, pp. 88-97
-
-
Kokjohn, T.A.1
Roher, A.E.2
-
73
-
-
33947582998
-
Site-specific UBITh amyloid-beta vaccine for immunotherapy of Alzheimer's disease
-
C.Y. Wang, C.L. Finstad, A.M. Walfield, C. Sia, K.K. Sokoll, T.Y. Chang, and et al. Site-specific UBITh amyloid-beta vaccine for immunotherapy of Alzheimer's disease Vaccine 25 2007 3041 3052
-
(2007)
Vaccine
, vol.25
, pp. 3041-3052
-
-
Wang, C.Y.1
Finstad, C.L.2
Walfield, A.M.3
Sia, C.4
Sokoll, K.K.5
Chang, T.Y.6
-
74
-
-
76849109048
-
Results of the first-in-man study with the active Abeta immunotherapy CAD106 in Alzheimer's patients
-
B.G. Winblad, L. Minthon, A. Floesser, G. Imbert, T. Dumortier, Y. He, and et al. Results of the first-in-man study with the active Abeta immunotherapy CAD106 in Alzheimer's patients Alzheimers Dement 5 4, suppl. 2009 113 114
-
(2009)
Alzheimers Dement
, vol.5
, Issue.4
, pp. 113-114
-
-
Winblad, B.G.1
Minthon, L.2
Floesser, A.3
Imbert, G.4
Dumortier, T.5
He, Y.6
-
75
-
-
36248941497
-
Alzheimer's disease peptide epitope vaccine reduces insoluble but not soluble/oligomeric A{beta} species in amyloid precursor protein transgenic mice
-
I. Petrushina, A. Ghochikyan, M. Mktrichyan, G. Mamikonyan, N. Movsesyan, H. Davtyan, and et al. Alzheimer's disease peptide epitope vaccine reduces insoluble but not soluble/oligomeric A{beta} species in amyloid precursor protein transgenic mice J Neurosci 27 2007 12721 12731
-
(2007)
J Neurosci
, vol.27
, pp. 12721-12731
-
-
Petrushina, I.1
Ghochikyan, A.2
Mktrichyan, M.3
Mamikonyan, G.4
Movsesyan, N.5
Davtyan, H.6
-
76
-
-
84899637729
-
The MultiTEP platform-based Alzheimer's disease epitope vaccine activates a broad repertoire of T helper cells in nonhuman primates
-
H. Davtyan, A. Ghochikyan, I. Petrushina, A. Hovakimyan, A. Davtyan, D.H. Cribbs, and et al. The MultiTEP platform-based Alzheimer's disease epitope vaccine activates a broad repertoire of T helper cells in nonhuman primates Alzheimers Dement 10 2014 271 283
-
(2014)
Alzheimers Dement
, vol.10
, pp. 271-283
-
-
Davtyan, H.1
Ghochikyan, A.2
Petrushina, I.3
Hovakimyan, A.4
Davtyan, A.5
Cribbs, D.H.6
-
77
-
-
67849102202
-
Anti-amyloid-beta immunotherapy in Alzheimer's disease: ACC-001 clinical trials are ongoing
-
J.M. Ryan, and M. Grundman Anti-amyloid-beta immunotherapy in Alzheimer's disease: ACC-001 clinical trials are ongoing J Alzheimers Dis 17 2009 243
-
(2009)
J Alzheimers Dis
, vol.17
, pp. 243
-
-
Ryan, J.M.1
Grundman, M.2
-
79
-
-
84886937126
-
Immunotherapy for Alzheimer's disease: Hoops and hurdles
-
C.A. Lemere Immunotherapy for Alzheimer's disease: Hoops and hurdles Mol Neurodegener 8 2013 36
-
(2013)
Mol Neurodegener
, vol.8
, pp. 36
-
-
Lemere, C.A.1
-
80
-
-
84894366258
-
Amyloid-based immunotherapy for Alzheimer's disease in the time of prevention trials: The way forward
-
F. Panza, V. Solfrizzi, B.P. Imbimbo, R. Tortelli, A. Santamato, and G. Logroscino Amyloid-based immunotherapy for Alzheimer's disease in the time of prevention trials: The way forward Expert Rev Clin Immunol 10 2014 405 419
-
(2014)
Expert Rev Clin Immunol
, vol.10
, pp. 405-419
-
-
Panza, F.1
Solfrizzi, V.2
Imbimbo, B.P.3
Tortelli, R.4
Santamato, A.5
Logroscino, G.6
-
81
-
-
84893295027
-
Active immunotherapy options for Alzheimer's disease
-
B. Winblad, A. Graf, M.E. Riviere, N. Andreasen, and J.M. Ryan Active immunotherapy options for Alzheimer's disease Alzheimers Res Ther 6 2014 7
-
(2014)
Alzheimers Res Ther
, vol.6
, pp. 7
-
-
Winblad, B.1
Graf, A.2
Riviere, M.E.3
Andreasen, N.4
Ryan, J.M.5
-
82
-
-
84889770121
-
Key roles of adjuvants in modern vaccines
-
S.G. Reed, M.T. Orr, and C.B. Fox Key roles of adjuvants in modern vaccines Nat Med 19 2013 1597 1608
-
(2013)
Nat Med
, vol.19
, pp. 1597-1608
-
-
Reed, S.G.1
Orr, M.T.2
Fox, C.B.3
-
83
-
-
40549113071
-
Freeing vaccine adjuvants from dangerous immunological dogma
-
N. Petrovsky Freeing vaccine adjuvants from dangerous immunological dogma Expert Rev Vaccines 7 2008 7 10
-
(2008)
Expert Rev Vaccines
, vol.7
, pp. 7-10
-
-
Petrovsky, N.1
-
84
-
-
34547473731
-
Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice
-
A. Muhs, D.T. Hickman, M. Pihlgren, N. Chuard, V. Giriens, C. Meerschman, and et al. Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice Proc Natl Acad Sci U S A 104 2007 9810 9815
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 9810-9815
-
-
Muhs, A.1
Hickman, D.T.2
Pihlgren, M.3
Chuard, N.4
Giriens, V.5
Meerschman, C.6
-
85
-
-
84899623721
-
Epitope-based DNA vaccine for Alzheimer's disease: Translational study in macaques
-
C.F. Evans, H. Davtyan, I. Petrushina, A. Hovakimyan, A. Davtyan, D. Hannaman, and et al. Epitope-based DNA vaccine for Alzheimer's disease: Translational study in macaques Alzheimers Dement 10 2014 284 295
-
(2014)
Alzheimers Dement
, vol.10
, pp. 284-295
-
-
Evans, C.F.1
Davtyan, H.2
Petrushina, I.3
Hovakimyan, A.4
Davtyan, A.5
Hannaman, D.6
-
87
-
-
84945471231
-
-
Accessed July 30, 2015
-
AlzForum Vanutide cridificar Available at: http://www.alzforum.org/therapeutics/vanutide-cridificar Accessed July 30, 2015
-
Vanutide cridificar
-
-
-
88
-
-
84945489542
-
-
V950-001 AM7. Identifier: NCT00464334
-
V950-001 AM7. ClinicalTrials.gov Identifier: NCT00464334. 2014.
-
(2014)
-
-
-
89
-
-
84862331908
-
Safety, tolerability, and antibody response of active Abeta immunotherapy with CAD106 in patients with Alzheimer's disease: Randomised, double-blind, placebo-controlled, first-in-human study
-
B. Winblad, N. Andreasen, L. Minthon, A. Floesser, G. Imbert, T. Dumortier, and et al. Safety, tolerability, and antibody response of active Abeta immunotherapy with CAD106 in patients with Alzheimer's disease: Randomised, double-blind, placebo-controlled, first-in-human study Lancet Neurol 11 2012 597 604
-
(2012)
Lancet Neurol
, vol.11
, pp. 597-604
-
-
Winblad, B.1
Andreasen, N.2
Minthon, L.3
Floesser, A.4
Imbert, G.5
Dumortier, T.6
-
90
-
-
78649360495
-
AFFITOME(R) technology in neurodegenerative diseases: The doubling advantage
-
A. Schneeberger, M. Mandler, F. Mattner, and W. Schmidt AFFITOME(R) technology in neurodegenerative diseases: The doubling advantage Hum Vaccin 6 2010 948 952
-
(2010)
Hum Vaccin
, vol.6
, pp. 948-952
-
-
Schneeberger, A.1
Mandler, M.2
Mattner, F.3
Schmidt, W.4
-
91
-
-
84928991840
-
Vanutide cridificar and the QS-21 adjuvant in Japanese subjects with mild to moderate Alzheimer's disease: Results from two phase 2 studies
-
H. Arai, H. Suzuki, and T. Yoshiyama Vanutide cridificar and the QS-21 adjuvant in Japanese subjects with mild to moderate Alzheimer's disease: Results from two phase 2 studies Curr Alzheimer Res 12 2015 242 254
-
(2015)
Curr Alzheimer Res
, vol.12
, pp. 242-254
-
-
Arai, H.1
Suzuki, H.2
Yoshiyama, T.3
-
92
-
-
84892695519
-
Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease
-
S. Salloway, R. Sperling, N.C. Fox, K. Blennow, W. Klunk, M. Raskind, and et al. Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease N Engl J Med 370 2014 322 333
-
(2014)
N Engl J Med
, vol.370
, pp. 322-333
-
-
Salloway, S.1
Sperling, R.2
Fox, N.C.3
Blennow, K.4
Klunk, W.5
Raskind, M.6
-
93
-
-
84892748542
-
Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease
-
R.S. Doody, R.G. Thomas, M. Farlow, T. Iwatsubo, B. Vellas, S. Joffe, and et al. Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease N Engl J Med 370 2014 311 321
-
(2014)
N Engl J Med
, vol.370
, pp. 311-321
-
-
Doody, R.S.1
Thomas, R.G.2
Farlow, M.3
Iwatsubo, T.4
Vellas, B.5
Joffe, S.6
-
94
-
-
84880174238
-
Definitions of dementia and predementia states in Alzheimer's disease and vascular cognitive impairment: Consensus from the Canadian conference on diagnosis of dementia
-
H. Chertkow, H.H. Feldman, C. Jacova, and F. Massoud Definitions of dementia and predementia states in Alzheimer's disease and vascular cognitive impairment: Consensus from the Canadian conference on diagnosis of dementia Alzheimers Res Ther 5 Suppl 1 2013 S2
-
(2013)
Alzheimers Res Ther
, vol.5
, pp. S2
-
-
Chertkow, H.1
Feldman, H.H.2
Jacova, C.3
Massoud, F.4
-
95
-
-
84881478550
-
Ushering in the study and treatment of preclinical Alzheimer disease
-
J.B. Langbaum, A.S. Fleisher, K. Chen, N. Ayutyanont, F. Lopera, Y.T. Quiroz, and et al. Ushering in the study and treatment of preclinical Alzheimer disease Nat Rev Neurol 9 2013 371 381
-
(2013)
Nat Rev Neurol
, vol.9
, pp. 371-381
-
-
Langbaum, J.B.1
Fleisher, A.S.2
Chen, K.3
Ayutyanont, N.4
Lopera, F.5
Quiroz, Y.T.6
-
98
-
-
84899047367
-
The A4 study: Stopping AD before symptoms begin?
-
R.A. Sperling, D.M. Rentz, K.A. Johnson, J. Karlawish, M. Donohue, D.P. Salmon, and et al. The A4 study: Stopping AD before symptoms begin? Sci Transl Med 6 2014 228fs13
-
(2014)
Sci Transl Med
, vol.6
, pp. 228fs13
-
-
Sperling, R.A.1
Rentz, D.M.2
Johnson, K.A.3
Karlawish, J.4
Donohue, M.5
Salmon, D.P.6
-
100
-
-
84897954153
-
New perspectives on the role of tau in Alzheimer's disease. Implications for therapy
-
M. Medina, and J. Avila New perspectives on the role of tau in Alzheimer's disease. Implications for therapy Biochem Pharmacol 88 2014 540 547
-
(2014)
Biochem Pharmacol
, vol.88
, pp. 540-547
-
-
Medina, M.1
Avila, J.2
-
101
-
-
33646066257
-
Amyloid-beta immunotherapy for the prevention and treatment of Alzheimer disease: Lessons from mice, monkeys, and humans
-
C.A. Lemere, M. Maier, L. Jiang, Y. Peng, and T.J. Seabrook Amyloid-beta immunotherapy for the prevention and treatment of Alzheimer disease: Lessons from mice, monkeys, and humans Rejuvenation Res 9 2006 77 84
-
(2006)
Rejuvenation Res
, vol.9
, pp. 77-84
-
-
Lemere, C.A.1
Maier, M.2
Jiang, L.3
Peng, Y.4
Seabrook, T.J.5
-
102
-
-
33646938005
-
Short amyloid-beta (Abeta) immunogens reduce cerebral Abeta load and learning deficits in an Alzheimer's disease mouse model in the absence of an Abeta-specific cellular immune response
-
M. Maier, T.J. Seabrook, N.D. Lazo, L. Jiang, P. Das, C. Janus, and et al. Short amyloid-beta (Abeta) immunogens reduce cerebral Abeta load and learning deficits in an Alzheimer's disease mouse model in the absence of an Abeta-specific cellular immune response J Neurosci 26 2006 4717 4728
-
(2006)
J Neurosci
, vol.26
, pp. 4717-4728
-
-
Maier, M.1
Seabrook, T.J.2
Lazo, N.D.3
Jiang, L.4
Das, P.5
Janus, C.6
-
103
-
-
80051563156
-
Effect of rice-expressed amyloid beta in the Tg2576 Alzheimer's disease transgenic mouse model
-
J. Nojima, A. Maeda, S. Aoki, S. Suo, D. Yanagihara, Y. Watanabe, and et al. Effect of rice-expressed amyloid beta in the Tg2576 Alzheimer's disease transgenic mouse model Vaccine 29 2011 6252 6258
-
(2011)
Vaccine
, vol.29
, pp. 6252-6258
-
-
Nojima, J.1
Maeda, A.2
Aoki, S.3
Suo, S.4
Yanagihara, D.5
Watanabe, Y.6
-
104
-
-
84871558491
-
Pushing the frontiers of T-cell vaccines: Accurate measurement of human T-cell responses
-
F. Saade, S.A. Gorski, and N. Petrovsky Pushing the frontiers of T-cell vaccines: Accurate measurement of human T-cell responses Expert Rev Vaccines 11 2012 1459 1470
-
(2012)
Expert Rev Vaccines
, vol.11
, pp. 1459-1470
-
-
Saade, F.1
Gorski, S.A.2
Petrovsky, N.3
-
105
-
-
53949089356
-
Immunity, ageing and cancer
-
E. Derhovanessian, R. Solana, A. Larbi, and G. Pawelec Immunity, ageing and cancer Immun Ageing 5 2008 11
-
(2008)
Immun Ageing
, vol.5
, pp. 11
-
-
Derhovanessian, E.1
Solana, R.2
Larbi, A.3
Pawelec, G.4
-
106
-
-
84876535364
-
Understanding immunosenescence to improve responses to vaccines
-
J.J. Goronzy, and C.M. Weyand Understanding immunosenescence to improve responses to vaccines Nat Immunol 14 2013 428 436
-
(2013)
Nat Immunol
, vol.14
, pp. 428-436
-
-
Goronzy, J.J.1
Weyand, C.M.2
-
107
-
-
40449086748
-
Progress in the active immunotherapeutic approach to Alzheimer's disease: Clinical investigations into AN1792-associated meningoencephalitis
-
M. Pride, P. Seubert, M. Grundman, M. Hagen, J. Eldridge, and R.S. Black Progress in the active immunotherapeutic approach to Alzheimer's disease: Clinical investigations into AN1792-associated meningoencephalitis Neurodegener Dis 5 2008 194 196
-
(2008)
Neurodegener Dis
, vol.5
, pp. 194-196
-
-
Pride, M.1
Seubert, P.2
Grundman, M.3
Hagen, M.4
Eldridge, J.5
Black, R.S.6
-
108
-
-
84928569750
-
Long-term treatment with active Abeta immunotherapy with CAD106 in mild Alzheimer's disease
-
M.R. Farlow, N. Andreasen, M.E. Riviere, I. Vostiar, A. Vitaliti, J. Sovago, and et al. Long-term treatment with active Abeta immunotherapy with CAD106 in mild Alzheimer's disease Alzheimers Res Ther 7 2015 23
-
(2015)
Alzheimers Res Ther
, vol.7
, pp. 23
-
-
Farlow, M.R.1
Andreasen, N.2
Riviere, M.E.3
Vostiar, I.4
Vitaliti, A.5
Sovago, J.6
-
109
-
-
84945491831
-
Aβ-specific antibodies induced by active immunotherapy CAD106 engage Aβ in plasma in AD patients
-
B. Winblad, M. Farlow, K. Blennow, I. Vostiar, G. Imbert, A. Tomovic, and et al. Aβ-specific antibodies induced by active immunotherapy CAD106 engage Aβ in plasma in AD patients Alzheimers Dement 7 2011 S334
-
(2011)
Alzheimers Dement
, vol.7
, pp. S334
-
-
Winblad, B.1
Farlow, M.2
Blennow, K.3
Vostiar, I.4
Imbert, G.5
Tomovic, A.6
-
110
-
-
84878805578
-
Refinement of a DNA based Alzheimer's disease epitope vaccine in rabbits
-
A. Ghochikyan, H. Davtyan, I. Petrushina, A. Hovakimyan, N. Movsesyan, A. Davtyan, and et al. Refinement of a DNA based Alzheimer's disease epitope vaccine in rabbits Hum Vaccin Immunother 9 2013 1002 1010
-
(2013)
Hum Vaccin Immunother
, vol.9
, pp. 1002-1010
-
-
Ghochikyan, A.1
Davtyan, H.2
Petrushina, I.3
Hovakimyan, A.4
Movsesyan, N.5
Davtyan, A.6
-
111
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
R. Kayed, E. Head, J.L. Thompson, T.M. McIntire, S.C. Milton, C.W. Cotman, and et al. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis Science 300 2003 486 489
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
-
112
-
-
0036852750
-
Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis
-
J. McLaurin, R. Cecal, M.E. Kierstead, X. Tian, A.L. Phinney, M. Manea, and et al. Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis Nat Med 8 2002 1263 1269
-
(2002)
Nat Med
, vol.8
, pp. 1263-1269
-
-
McLaurin, J.1
Cecal, R.2
Kierstead, M.E.3
Tian, X.4
Phinney, A.L.5
Manea, M.6
-
113
-
-
34547955761
-
Anti-Abeta 1-11 antibody binds to different beta-amyloid species, inhibits fibril formation, and disaggregates preformed fibrils, but not the most toxic oligomers
-
G. Mamikonyan, M. Necula, M. Mkrtichyan, A. Ghochikyan, I. Petrushina, N. Movsesyan, and et al. Anti-Abeta 1-11 antibody binds to different beta-amyloid species, inhibits fibril formation, and disaggregates preformed fibrils, but not the most toxic oligomers J Biol Chem 282 2007 22376 22386
-
(2007)
J Biol Chem
, vol.282
, pp. 22376-22386
-
-
Mamikonyan, G.1
Necula, M.2
Mkrtichyan, M.3
Ghochikyan, A.4
Petrushina, I.5
Movsesyan, N.6
-
114
-
-
0345862278
-
Effect of different anti-Abeta antibodies on Abeta fibrillogenesis as assessed by atomic force microscopy
-
J. Legleiter, D.L. Czilli, B. Gitter, R.B. DeMattos, D.M. Holtzman, and T. Kowalewski Effect of different anti-Abeta antibodies on Abeta fibrillogenesis as assessed by atomic force microscopy J Mol Biol 335 2004 997 1006
-
(2004)
J Mol Biol
, vol.335
, pp. 997-1006
-
-
Legleiter, J.1
Czilli, D.L.2
Gitter, B.3
DeMattos, R.B.4
Holtzman, D.M.5
Kowalewski, T.6
-
115
-
-
84874343214
-
Prevention of amyloid-beta fibril formation using antibodies against the C-terminal region of amyloid-beta1-40 and amyloid-beta1-42
-
M. Montanes, D. Casabona, L. Sarasa, P. Pesini, and M. Sarasa Prevention of amyloid-beta fibril formation using antibodies against the C-terminal region of amyloid-beta1-40 and amyloid-beta1-42 J Alzheimers Dis 34 2013 133 137
-
(2013)
J Alzheimers Dis
, vol.34
, pp. 133-137
-
-
Montanes, M.1
Casabona, D.2
Sarasa, L.3
Pesini, P.4
Sarasa, M.5
-
116
-
-
0021572655
-
Identification of subjects with a high risk of developing type I diabetes. Summary of a workshop, held on May 25th, 1984, in the Children's Hospital in Basel, Switzerland
-
W. Berger Identification of subjects with a high risk of developing type I diabetes. Summary of a workshop, held on May 25th, 1984, in the Children's Hospital in Basel, Switzerland Bull Schweiz Akad Med Wiss 1984 81 85
-
(1984)
Bull Schweiz Akad Med Wiss
, pp. 81-85
-
-
Berger, W.1
-
117
-
-
0031738116
-
Combined use of autoantibodies (IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell antibodies) in type 1 diabetes: Combinatorial Islet Autoantibody Workshop
-
C.F. Verge, D. Stenger, E. Bonifacio, P.G. Colman, C. Pilcher, P.J. Bingley, and et al. Combined use of autoantibodies (IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell antibodies) in type 1 diabetes: Combinatorial Islet Autoantibody Workshop Diabetes 47 1998 1857 1866
-
(1998)
Diabetes
, vol.47
, pp. 1857-1866
-
-
Verge, C.F.1
Stenger, D.2
Bonifacio, E.3
Colman, P.G.4
Pilcher, C.5
Bingley, P.J.6
-
118
-
-
79952279727
-
Measurement of islet cell antibodies in the Type 1 Diabetes Genetics Consortium: Efforts to harmonize procedures among the laboratories
-
P.J. Bingley, A.J. Williams, P.G. Colman, S.A. Gellert, G. Eisenbarth, L. Yu, and et al. Measurement of islet cell antibodies in the Type 1 Diabetes Genetics Consortium: Efforts to harmonize procedures among the laboratories Clin Trials 7 1 Suppl 2010 S56 S64
-
(2010)
Clin Trials
, vol.7
, Issue.1
, pp. S56-S64
-
-
Bingley, P.J.1
Williams, A.J.2
Colman, P.G.3
Gellert, S.A.4
Eisenbarth, G.5
Yu, L.6
-
119
-
-
0032993872
-
The development of a World Health Organisation international standard for islet cell antibodies: The aims and design of an international collaborative study
-
A.R. Mire-Sluis, R.G. Das, and A. Lernmark The development of a World Health Organisation international standard for islet cell antibodies: The aims and design of an international collaborative study Diabetes Metab Res Rev 15 1999 72 77
-
(1999)
Diabetes Metab Res Rev
, vol.15
, pp. 72-77
-
-
Mire-Sluis, A.R.1
Das, R.G.2
Lernmark, A.3
-
120
-
-
0032880017
-
Autoreactive T cell responses in insulin-dependent (Type 1) diabetes mellitus. Report of the first international workshop for standardization of T cell assays
-
B.O. Roep, M.A. Atkinson, P.M. van Endert, P.A. Gottlieb, S.B. Wilson, and J.A. Sachs Autoreactive T cell responses in insulin-dependent (Type 1) diabetes mellitus. Report of the first international workshop for standardization of T cell assays J Autoimmun 13 1999 267 282
-
(1999)
J Autoimmun
, vol.13
, pp. 267-282
-
-
Roep, B.O.1
Atkinson, M.A.2
Van Endert, P.M.3
Gottlieb, P.A.4
Wilson, S.B.5
Sachs, J.A.6
-
121
-
-
84908290432
-
First-in-man tau vaccine targeting structural determinants essential for pathological tau-tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheimer's disease model
-
E. Kontsekova, N. Zilka, B. Kovacech, P. Novak, and M. Novak First-in-man tau vaccine targeting structural determinants essential for pathological tau-tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheimer's disease model Alzheimers Res Ther 6 2014 44
-
(2014)
Alzheimers Res Ther
, vol.6
, pp. 44
-
-
Kontsekova, E.1
Zilka, N.2
Kovacech, B.3
Novak, P.4
Novak, M.5
-
123
-
-
84945436401
-
-
Accessed July 30, 2015
-
AlzForum ACI-35 Available at: http://www.alzforum.org/therapeutics/aci-35 Accessed July 30, 2015
-
ACI-35
-
-
-
124
-
-
34548036227
-
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
-
C. Ballatore, V.M. Lee, and J.Q. Trojanowski Tau-mediated neurodegeneration in Alzheimer's disease and related disorders Nat Rev Neurosci 8 2007 663 672
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 663-672
-
-
Ballatore, C.1
Lee, V.M.2
Trojanowski, J.Q.3
-
126
-
-
84896549213
-
Amyloid and tau in the brain in sporadic Alzheimer's disease: Defining the chicken and the egg
-
C.A. Hawkes, R.O. Carare, and R.O. Weller Amyloid and tau in the brain in sporadic Alzheimer's disease: Defining the chicken and the egg Acta Neuropathol 127 2014 617 618
-
(2014)
Acta Neuropathol
, vol.127
, pp. 617-618
-
-
Hawkes, C.A.1
Carare, R.O.2
Weller, R.O.3
-
127
-
-
84885476621
-
Amyloid or tau: The chicken or the egg?
-
D.M. Mann, and J. Hardy Amyloid or tau: The chicken or the egg? Acta Neuropathol 126 2013 609 613
-
(2013)
Acta Neuropathol
, vol.126
, pp. 609-613
-
-
Mann, D.M.1
Hardy, J.2
-
128
-
-
84885474583
-
Reply: The early pathological process in sporadic Alzheimer's disease
-
H. Braak, and K. Del Tredici Reply: The early pathological process in sporadic Alzheimer's disease Acta Neuropathol 126 2013 615 618
-
(2013)
Acta Neuropathol
, vol.126
, pp. 615-618
-
-
Braak, H.1
Del Tredici, K.2
-
129
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
H. Braak, and E. Braak Neuropathological stageing of Alzheimer-related changes Acta Neuropathol (Berl) 82 1991 239 259
-
(1991)
Acta Neuropathol (Berl)
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
130
-
-
0023200370
-
Histopathological criteria for progressive dementia disorders: Clinical-pathological correlation and classification by multivariate data analysis
-
I. Alafuzoff, K. Iqbal, H. Friden, R. Adolfsson, and B. Winblad Histopathological criteria for progressive dementia disorders: Clinical-pathological correlation and classification by multivariate data analysis Acta Neuropathol 74 1987 209 225
-
(1987)
Acta Neuropathol
, vol.74
, pp. 209-225
-
-
Alafuzoff, I.1
Iqbal, K.2
Friden, H.3
Adolfsson, R.4
Winblad, B.5
-
131
-
-
0014851803
-
Observations on the brains of demented old people
-
B.E. Tomlinson, G. Blessed, and M. Roth Observations on the brains of demented old people J Neurol Sci 11 1970 205 242
-
(1970)
J Neurol Sci
, vol.11
, pp. 205-242
-
-
Tomlinson, B.E.1
Blessed, G.2
Roth, M.3
-
132
-
-
84872379077
-
Tracking pathophysiological processes in Alzheimer's disease: An updated hypothetical model of dynamic biomarkers
-
C.R. Jack Jr., D.S. Knopman, W.J. Jagust, R.C. Petersen, M.W. Weiner, P.S. Aisen, and et al. Tracking pathophysiological processes in Alzheimer's disease: An updated hypothetical model of dynamic biomarkers Lancet Neurol 12 2013 207 216
-
(2013)
Lancet Neurol
, vol.12
, pp. 207-216
-
-
Jack, C.R.1
Knopman, D.S.2
Jagust, W.J.3
Petersen, R.C.4
Weiner, M.W.5
Aisen, P.S.6
-
133
-
-
84865529158
-
Clinical and biomarker changes in dominantly inherited Alzheimer's disease
-
R.J. Bateman, C. Xiong, T.L. Benzinger, A.M. Fagan, A. Goate, N.C. Fox, and et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease N Engl J Med 367 2012 795 804
-
(2012)
N Engl J Med
, vol.367
, pp. 795-804
-
-
Bateman, R.J.1
Xiong, C.2
Benzinger, T.L.3
Fagan, A.M.4
Goate, A.5
Fox, N.C.6
-
134
-
-
84883502695
-
Formation and propagation of tau oligomeric seeds
-
J.E. Gerson, and R. Kayed Formation and propagation of tau oligomeric seeds Front Neurol 4 2013 93
-
(2013)
Front Neurol
, vol.4
, pp. 93
-
-
Gerson, J.E.1
Kayed, R.2
-
135
-
-
84876250854
-
"Prion-like" templated misfolding in tauopathies
-
F. Clavaguera, I. Lavenir, B. Falcon, S. Frank, M. Goedert, and M. Tolnay "Prion-like" templated misfolding in tauopathies Brain Pathol 23 2013 342 349
-
(2013)
Brain Pathol
, vol.23
, pp. 342-349
-
-
Clavaguera, F.1
Lavenir, I.2
Falcon, B.3
Frank, S.4
Goedert, M.5
Tolnay, M.6
-
136
-
-
84885783467
-
Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo
-
K. Yanamandra, N. Kfoury, H. Jiang, T.E. Mahan, S. Ma, S.E. Maloney, and et al. Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo Neuron 80 2013 402 414
-
(2013)
Neuron
, vol.80
, pp. 402-414
-
-
Yanamandra, K.1
Kfoury, N.2
Jiang, H.3
Mahan, T.E.4
Ma, S.5
Maloney, S.E.6
-
137
-
-
77249133010
-
Prion-like mechanisms in neurodegenerative diseases
-
B. Frost, and M.I. Diamond Prion-like mechanisms in neurodegenerative diseases Nat Rev Neurosci 11 2010 155 159
-
(2010)
Nat Rev Neurosci
, vol.11
, pp. 155-159
-
-
Frost, B.1
Diamond, M.I.2
-
138
-
-
79955441814
-
Seeding of normal tau by pathological tau conformers drives pathogenesis of Alzheimer-like tangles
-
J.L. Guo, and V.M. Lee Seeding of normal tau by pathological tau conformers drives pathogenesis of Alzheimer-like tangles J Biol Chem 286 2011 15317 15331
-
(2011)
J Biol Chem
, vol.286
, pp. 15317-15331
-
-
Guo, J.L.1
Lee, V.M.2
-
139
-
-
84856454190
-
Trans-synaptic spread of tau pathology in vivo
-
L. Liu, V. Drouet, J.W. Wu, M.P. Witter, S.A. Small, C. Clelland, and et al. Trans-synaptic spread of tau pathology in vivo PLoS One 7 2012 e31302
-
(2012)
PLoS One
, vol.7
-
-
Liu, L.1
Drouet, V.2
Wu, J.W.3
Witter, M.P.4
Small, S.A.5
Clelland, C.6
-
140
-
-
84903535019
-
Ectosomes: A new mechanism for non-exosomal secretion of tau protein
-
S. Dujardin, S. Begard, R. Caillierez, C. Lachaud, L. Delattre, S. Carrier, and et al. Ectosomes: A new mechanism for non-exosomal secretion of tau protein PLoS One 9 2014 e100760
-
(2014)
PLoS One
, vol.9
-
-
Dujardin, S.1
Begard, S.2
Caillierez, R.3
Lachaud, C.4
Delattre, L.5
Carrier, S.6
-
142
-
-
80855148196
-
Immunotherapy for tauopathies
-
J. Gu, and E.M. Sigurdsson Immunotherapy for tauopathies J Mol Neurosci 45 2011 690 695
-
(2011)
J Mol Neurosci
, vol.45
, pp. 690-695
-
-
Gu, J.1
Sigurdsson, E.M.2
-
143
-
-
34548146119
-
Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements
-
A.A. Asuni, A. Boutajangout, D. Quartermain, and E.M. Sigurdsson Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements J Neurosci 27 2007 9115 9129
-
(2007)
J Neurosci
, vol.27
, pp. 9115-9129
-
-
Asuni, A.A.1
Boutajangout, A.2
Quartermain, D.3
Sigurdsson, E.M.4
-
144
-
-
78650065372
-
Immunotherapy targeting pathological tau prevents cognitive decline in a new tangle mouse model
-
A. Boutajangout, D. Quartermain, and E.M. Sigurdsson Immunotherapy targeting pathological tau prevents cognitive decline in a new tangle mouse model J Neurosci 30 2010 16559 16566
-
(2010)
J Neurosci
, vol.30
, pp. 16559-16566
-
-
Boutajangout, A.1
Quartermain, D.2
Sigurdsson, E.M.3
-
145
-
-
77954656871
-
Efficacy and safety of immunization with phosphorylated tau against neurofibrillary tangles in mice
-
M. Boimel, N. Grigoriadis, A. Lourbopoulos, E. Haber, O. Abramsky, and H. Rosenmann Efficacy and safety of immunization with phosphorylated tau against neurofibrillary tangles in mice Exp Neurol 224 2010 472 485
-
(2010)
Exp Neurol
, vol.224
, pp. 472-485
-
-
Boimel, M.1
Grigoriadis, N.2
Lourbopoulos, A.3
Haber, E.4
Abramsky, O.5
Rosenmann, H.6
-
146
-
-
33749614555
-
Tauopathy-like abnormalities and neurologic deficits in mice immunized with neuronal tau protein
-
H. Rosenmann, N. Grigoriadis, D. Karussis, M. Boimel, O. Touloumi, H. Ovadia, and et al. Tauopathy-like abnormalities and neurologic deficits in mice immunized with neuronal tau protein Arch Neurol 63 2006 1459 1467
-
(2006)
Arch Neurol
, vol.63
, pp. 1459-1467
-
-
Rosenmann, H.1
Grigoriadis, N.2
Karussis, D.3
Boimel, M.4
Touloumi, O.5
Ovadia, H.6
-
147
-
-
82955194797
-
Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice
-
M. Bi, A. Ittner, Y.D. Ke, J. Gotz, and L.M. Ittner Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice PLoS One 6 2011 e26860
-
(2011)
PLoS One
, vol.6
-
-
Bi, M.1
Ittner, A.2
Ke, Y.D.3
Gotz, J.4
Ittner, L.M.5
-
148
-
-
33746652117
-
Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits
-
K. Schindowski, A. Bretteville, K. Leroy, S. Begard, J.P. Brion, M. Hamdane, and et al. Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits Am J Pathol 169 2006 599 616
-
(2006)
Am J Pathol
, vol.169
, pp. 599-616
-
-
Schindowski, K.1
Bretteville, A.2
Leroy, K.3
Begard, S.4
Brion, J.P.5
Hamdane, M.6
-
149
-
-
34548829896
-
Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice
-
K. Leroy, A. Bretteville, K. Schindowski, E. Gilissen, M. Authelet, R. De Decker, and et al. Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice Am J Pathol 171 2007 976 992
-
(2007)
Am J Pathol
, vol.171
, pp. 976-992
-
-
Leroy, K.1
Bretteville, A.2
Schindowski, K.3
Gilissen, E.4
Authelet, M.5
De Decker, R.6
-
150
-
-
84860531636
-
Targeting phospho-Ser422 by active tau immunotherapy in the THYTau22 mouse model: A suitable therapeutic approach
-
L. Troquier, R. Caillierez, S. Burnouf, F.J. Fernandez-Gomez, M.E. Grosjean, N. Zommer, and et al. Targeting phospho-Ser422 by active tau immunotherapy in the THYTau22 mouse model: A suitable therapeutic approach Curr Alzheimer Res 9 2012 397 405
-
(2012)
Curr Alzheimer Res
, vol.9
, pp. 397-405
-
-
Troquier, L.1
Caillierez, R.2
Burnouf, S.3
Fernandez-Gomez, F.J.4
Grosjean, M.E.5
Zommer, N.6
-
151
-
-
84922479255
-
Efficacy and safety of a liposome-based vaccine against protein tau, assessed in tau.P301L mice that model tauopathy
-
C. Theunis, N. Crespo-Biel, V. Gafner, M. Pihlgren, M.P. Lopez-Deber, P. Reis, and et al. Efficacy and safety of a liposome-based vaccine against protein tau, assessed in tau.P301L mice that model tauopathy PLoS One 8 2013 e72301
-
(2013)
PLoS One
, vol.8
-
-
Theunis, C.1
Crespo-Biel, N.2
Gafner, V.3
Pihlgren, M.4
Lopez-Deber, M.P.5
Reis, P.6
-
152
-
-
80053202160
-
Passive immunization with anti-tau antibodies in two transgenic models: Reduction of tau pathology and delay of disease progression
-
X. Chai, S. Wu, T.K. Murray, R. Kinley, C.V. Cella, H. Sims, and et al. Passive immunization with anti-tau antibodies in two transgenic models: Reduction of tau pathology and delay of disease progression J Biol Chem 286 2011 34457 34467
-
(2011)
J Biol Chem
, vol.286
, pp. 34457-34467
-
-
Chai, X.1
Wu, S.2
Murray, T.K.3
Kinley, R.4
Cella, C.V.5
Sims, H.6
-
153
-
-
84861758226
-
Trans-cellular propagation of tau aggregation by fibrillar species
-
N. Kfoury, B.B. Holmes, H. Jiang, D.M. Holtzman, and M.I. Diamond Trans-cellular propagation of tau aggregation by fibrillar species J Biol Chem 287 2012 19440 19451
-
(2012)
J Biol Chem
, vol.287
, pp. 19440-19451
-
-
Kfoury, N.1
Holmes, B.B.2
Jiang, H.3
Holtzman, D.M.4
Diamond, M.I.5
-
154
-
-
84896269359
-
Passive immunization with tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles
-
D.L. Castillo-Carranza, U. Sengupta, M.J. Guerrero-Munoz, C.A. Lasagna-Reeves, J.E. Gerson, G. Singh, and et al. Passive immunization with tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles J Neurosci 34 2014 4260 4272
-
(2014)
J Neurosci
, vol.34
, pp. 4260-4272
-
-
Castillo-Carranza, D.L.1
Sengupta, U.2
Guerrero-Munoz, M.J.3
Lasagna-Reeves, C.A.4
Gerson, J.E.5
Singh, G.6
-
156
-
-
84925464993
-
TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model
-
Y. Wang, M. Cella, K. Mallinson, J.D. Ulrich, K.L. Young, M.L. Robinette, and et al. TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model Cell 160 2015 1061 1071
-
(2015)
Cell
, vol.160
, pp. 1061-1071
-
-
Wang, Y.1
Cella, M.2
Mallinson, K.3
Ulrich, J.D.4
Young, K.L.5
Robinette, M.L.6
-
157
-
-
84924737031
-
TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models
-
T.R. Jay, C.M. Miller, P.J. Cheng, L.C. Graham, S. Bemiller, M.L. Broihier, and et al. TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models J Exp Med 212 2015 287 295
-
(2015)
J Exp Med
, vol.212
, pp. 287-295
-
-
Jay, T.R.1
Miller, C.M.2
Cheng, P.J.3
Graham, L.C.4
Bemiller, S.5
Broihier, M.L.6
-
158
-
-
0036900076
-
Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice
-
J. Tan, T. Town, F. Crawford, T. Mori, A. DelleDonne, R. Crescentini, and et al. Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice Nat Neurosci 5 2002 1288 1293
-
(2002)
Nat Neurosci
, vol.5
, pp. 1288-1293
-
-
Tan, J.1
Town, T.2
Crawford, F.3
Mori, T.4
DelleDonne, A.5
Crescentini, R.6
-
159
-
-
0033579382
-
Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation
-
J. Tan, T. Town, D. Paris, T. Mori, Z. Suo, F. Crawford, and et al. Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation Science 286 1999 2352 2355
-
(1999)
Science
, vol.286
, pp. 2352-2355
-
-
Tan, J.1
Town, T.2
Paris, D.3
Mori, T.4
Suo, Z.5
Crawford, F.6
-
160
-
-
18244397199
-
CD40 is expressed and functional on neuronal cells
-
J. Tan, T. Town, T. Mori, D. Obregon, Y. Wu, A. DelleDonne, and et al. CD40 is expressed and functional on neuronal cells EMBO J 21 2002 643 652
-
(2002)
EMBO J
, vol.21
, pp. 643-652
-
-
Tan, J.1
Town, T.2
Mori, T.3
Obregon, D.4
Wu, Y.5
DelleDonne, A.6
-
161
-
-
84920563152
-
Toll-like receptors in Alzheimer's disease: A therapeutic perspective
-
M.E. Gambuzza, V. Sofo, F.M. Salmeri, L. Soraci, S. Marino, and P. Bramanti Toll-like receptors in Alzheimer's disease: A therapeutic perspective CNS Neurol Disord Drug Targets 13 2014 1542 1558
-
(2014)
CNS Neurol Disord Drug Targets
, vol.13
, pp. 1542-1558
-
-
Gambuzza, M.E.1
Sofo, V.2
Salmeri, F.M.3
Soraci, L.4
Marino, S.5
Bramanti, P.6
-
162
-
-
84871887566
-
Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Abeta amyloidosis
-
J. Kim, A.E. Eltorai, H. Jiang, F. Liao, P.B. Verghese, F.R. Stewart, and et al. Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Abeta amyloidosis J Exp Med 209 2012 2149 2156
-
(2012)
J Exp Med
, vol.209
, pp. 2149-2156
-
-
Kim, J.1
Eltorai, A.E.2
Jiang, H.3
Liao, F.4
Verghese, P.B.5
Stewart, F.R.6
-
163
-
-
84922026428
-
Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology
-
M.V. Guillot-Sestier, K.R. Doty, D. Gate, J. Rodriguez Jr., B.P. Leung, K. Rezai-Zadeh, and et al. Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology Neuron 85 2015 534 548
-
(2015)
Neuron
, vol.85
, pp. 534-548
-
-
Guillot-Sestier, M.V.1
Doty, K.R.2
Gate, D.3
Rodriguez, J.4
Leung, B.P.5
Rezai-Zadeh, K.6
-
164
-
-
84922064574
-
IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior
-
P. Chakrabarty, A. Li, C. Ceballos-Diaz, J.A. Eddy, C.C. Funk, B. Moore, and et al. IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior Neuron 85 2015 519 533
-
(2015)
Neuron
, vol.85
, pp. 519-533
-
-
Chakrabarty, P.1
Li, A.2
Ceballos-Diaz, C.3
Eddy, J.A.4
Funk, C.C.5
Moore, B.6
-
165
-
-
44949173099
-
Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology
-
T. Town, Y. Laouar, C. Pittenger, T. Mori, C.A. Szekely, J. Tan, and et al. Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology Nat Med 14 2008 681 687
-
(2008)
Nat Med
, vol.14
, pp. 681-687
-
-
Town, T.1
Laouar, Y.2
Pittenger, C.3
Mori, T.4
Szekely, C.A.5
Tan, J.6
-
166
-
-
20444413356
-
Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease
-
E. Masliah, E. Rockenstein, A. Adame, M. Alford, L. Crews, M. Hashimoto, and et al. Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease Neuron 46 2005 857 868
-
(2005)
Neuron
, vol.46
, pp. 857-868
-
-
Masliah, E.1
Rockenstein, E.2
Adame, A.3
Alford, M.4
Crews, L.5
Hashimoto, M.6
|