Non-Fc-mediated mechanisms are involved in clearance of amyloid-β in vivo by immunotherapy

Journal of Neuroscience

Volumn 22, Issue 18, 2002, Pages 7873-7878

  Bacskai, Brian J ^a   Kajdasz, Stephen T ^a   McLellan, Megan E ^a   Games, Dora ^b   Seubert, Peter ^b   Schenk, Dale ^b   Hyman, Bradley T ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b ELAN PHARMACEUTICALS   (United States)

Author keywords

Alzheimer; Amyloid; Antibody; Imaging; Immunotherapy; Microglia; Multiphoton; Senile plaque; Transgenic

Indexed keywords

AMYLOID BETA PROTEIN; FC RECEPTOR; FLUORESCEIN ISOTHIOCYANATE; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2B;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE DISRUPTION; GENE OVEREXPRESSION; IMMUNOTHERAPY; IN VIVO STUDY; MICROGLIA; MICROSCOPY; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; SENILE PLAQUE; TRANSGENIC MOUSE;

EID: 0037107177     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-18-07873.2002     Document Type: Article

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