Thermodynamics of antibody - Antigen interaction revealed by mutation analysis of antibody variable regions

Journal of Biochemistry

Volumn 158, Issue 1, 2015, Pages 1-13

  Akiba, Hiroki ^a   Tsumoto, Kouhei ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Interaction; Isothermal titration calorimetry; Kinetics; Protein structure; Thermodynamics

Indexed keywords

AMINO ACID; ANTIBODY; ANTIGEN; AROMATIC AMINO ACID; EPIDERMAL GROWTH FACTOR RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; VASCULOTROPIN ANTIBODY; IMMUNOGLOBULIN VARIABLE REGION;

ANTIBODY ENGINEERING; ANTIGEN ANTIBODY COMPLEX; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ANTIGEN RECOGNITION; COMPLEX FORMATION; COVALENT BOND; ENTHALPY; ENTROPY; HEAVY CHAIN; HYDRATION; HYDROGEN BOND; HYDROPHOBICITY; ISOTHERMAL TITRATION CALORIMETRY; KINETIC PARAMETERS; LIGHT CHAIN; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; MUTATIONAL ANALYSIS; PHYSICAL CHEMISTRY; PROTEIN PROTEIN INTERACTION; REVERTANT; REVIEW; SITE DIRECTED MUTAGENESIS; STATIC ELECTRICITY; THERMODYNAMICS; GENETICS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; KINETICS; MUTATION;

ANTIGEN-ANTIBODY REACTIONS; HYDROGEN BONDING; IMMUNOGLOBULIN VARIABLE REGION; KINETICS; MUTATION; THERMODYNAMICS;

EID: 84943223497     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvv049     Document Type: Review

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