How protein recognizes ladder-like polycyclic ethers: Interactions between ciguatoxin (CTX3C) fragments and its specific antibody 10C9

Journal of Biological Chemistry

Volumn 283, Issue 28, 2008, Pages 19440-19447

  Ui, Mihoko ^a   Tanaka, Yoshikazu ^a   Tsumuraya, Takeshi ^b   Fujii, Ikuo ^b   Inoue, Masayuki ^a,c   Hirama, Masahiro ^c   Tsumoto, Kouhei ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b Osaka Prefecture University   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY STRUCTURES; ANTIGEN FRAGMENTS; ATOMIC LEVELS; BINDING POCKETS; FREE FORMS; MARINE TOXINS; MOLECULAR REARRANGEMENTS; PATHOGENIC MECHANISMS; POLYCYCLIC ETHERS; ROTATIONAL MOTIONS;

ANTIBODIES; CLARIFICATION; CRYSTAL STRUCTURE; ETHERS; FLOW INTERACTIONS; HYDROGEN; HYDROGEN BONDS; MACHINE DESIGN; METABOLITES; ORGANIC COMPOUNDS; REACTION KINETICS; VAN DER WAALS FORCES;

ANTIGENS;

10C9 ANTIBODY; ANTIBODY; CIGUATOXIN; ETHER DERIVATIVE; IMMUNOGLOBULIN F(AB) FRAGMENT; POLYCYCLIC ETHER; POLYCYCLIC HYDROCARBON; TOXIN ANTIBODY; UNCLASSIFIED DRUG; ANTITOXIN; CIGUATOXIN 3C; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANTIBODY SPECIFICITY; ANTIBODY STRUCTURE; ANTIGEN ANTIBODY COMPLEX; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ARTICLE; BINDING KINETICS; BINDING SITE; CIRCLING BEHAVIOR; CONTROLLED STUDY; CRYSTAL STRUCTURE; HYDROGEN BOND; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; THERMOSTABILITY; ANIMAL; ANTIBODY COMBINING SITE; CHEMISTRY; IMMUNOGLOBULIN CONSTANT REGION; IMMUNOLOGY; PROTEIN QUATERNARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY COMPLEX; ANTITOXINS; BINDING SITES, ANTIBODY; CIGUATOXINS; CRYSTALLOGRAPHY, X-RAY; IMMUNOGLOBULIN CONSTANT REGIONS; IMMUNOGLOBULIN VARIABLE REGION; MICE; POLYCYCLIC COMPOUNDS; PROTEIN STRUCTURE, QUATERNARY;

EID: 50349100083     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M801282200     Document Type: Article

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