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Biochemistry

Volumn 40, Issue 36, 2001, Pages 10764-10773

A comparative analysis of the immunological evolution of antibody 28B4

(7) Yin, J a,b Mundorff, E C b Yang, P L a Wendt, K U c Hanway, D a Stevens, R C a,b Schultz, P G a,b

a SCRIPPS RESEARCH INSTITUTE (United States)

b LAWRENCE BERKELEY NATIONAL LABORATORY (United States)

c SANOFI AVENTIS DEUTSCHLAND GMBH (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATIC MUTATIONS;

GENES; GENETIC ENGINEERING; HYDROPHOBICITY; PLASTICITY; X RAY CRYSTALLOGRAPHY;

ANTIBODIES;

4 NITROPHENOL; ANTIBODY; ANTIBODY 20 1; ANTIBODY 28B4; ANTIBODY NZA6; ASPARTIC ACID; HAPTEN; IMMUNOGLOBULIN F(AB) FRAGMENT; PHOSPHONIC ACID DERIVATIVE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANTIBODY STRUCTURE; ANTIGEN SPECIFICITY; ARTICLE; BINDING AFFINITY; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENE MUTATION; MOLECULAR EVOLUTION; MOLECULAR INTERACTION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, CATALYTIC; ANTIBODY AFFINITY; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; EVOLUTION, MOLECULAR; HAPTENS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; RECOMBINANT PROTEINS;

EID: 0035845637 PISSN: 00062960 EISSN: None Source Type: Journal
DOI: 10.1021/bi010536c Document Type: Article

Times cited : (66)

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