Molecular evolution of affinity and flexibility in the immune system

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 21, 2007, Pages 8821-8826

  Thorpe, Ian F ^a   Brooks III, Charles L ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Antibody; Binding; Entropy; Ligand association; Molecular recognition

Indexed keywords

ANTIBODY; ANTIGEN; LIGAND;

ANTIGEN ANTIBODY COMPLEX; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; ENERGY; ENTHALPY; ENTROPY; IMMUNE SYSTEM; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; MOLECULAR RECOGNITION; PRIORITY JOURNAL; CHEMISTRY; COMPUTER SIMULATION; GENETICS; IMMUNOLOGY; METABOLISM; PROTEIN BINDING; PROTEIN PROCESSING; PROTEIN QUATERNARY STRUCTURE; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

ANTIBODIES; ANTIGENS; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; EVOLUTION, MOLECULAR; IMMUNE SYSTEM; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, QUATERNARY; THERMODYNAMICS;

EID: 34547460183     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0610064104     Document Type: Article

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