Origins of specificity and affinity in antibody-protein interactions

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 26, 2014, Pages

  Peng, Hung Pin ^a,b,c   Lee, Kuo Hao ^a   Jian, Jhih Wei ^a,b,c   Yang, An Suei ^a  

^a GENOMICS RESEARCH CENTER   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c INSTITUTE OF INFORMATION SCIENCE   (Taiwan)

Author keywords

Epitope prediction; Functional epitope; Interface hot spot; Paratope prediction; Protein antigenic site

Indexed keywords

ALANINE; EPITOPE;

ANTIBODY AFFINITY; ANTIBODY COMBINING SITE; ANTIBODY PROTEIN INTERACTION; ANTIBODY SPECIFICITY; ANTIBODY STRUCTURE; ARTICLE; ATOM; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT;

EPITOPE PREDICTION; FUNCTIONAL EPITOPE; INTERFACE HOT SPOT; PARATOPE PREDICTION; PROTEIN ANTIGENIC SITE;

ALGORITHMS; ANTIBODY AFFINITY; ANTIGEN-ANTIBODY REACTIONS; BINDING SITES, ANTIBODY; COMPUTATIONAL BIOLOGY; EPITOPES; HUMANS; HYDROGEN BONDING; PROTEINS; SUBSTRATE SPECIFICITY;

EID: 84903742142     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1401131111     Document Type: Article

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