Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex: The case of HyHEL-10-HEL

Journal of Biological Chemistry

Volumn 282, Issue 9, 2007, Pages 6783-6791

  Shiroishi, Mitsunori ^a,d   Tsumoto, Kouhei ^a,b   Tanaka, Yoshikazu ^b   Yokota, Akiko ^a   Nakanishi, Takeshi ^a   Kondo, Hidemasa ^c   Kumagai, Izumi ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^d KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MUTATIONS; TERNARY STRUCTURES; THERMODYNAMIC ANALYSIS;

AMINO ACIDS; ANTIGENS; BINDING SITES; CRYSTALLOGRAPHY; ENZYMES; THERMODYNAMICS;

ANTIBODIES;

ANTIBODY; HEN EGG LYSOZYME ANTIBODY; HYDROXYL GROUP; LYSOZYME; TYROSINE; UNCLASSIFIED DRUG; EGG PROTEIN; IMMUNOGLOBULIN FRAGMENT; IMMUNOGLOBULIN FV;

ANTIBODY AFFINITY; ANTIBODY COMBINING SITE; ANTIGEN ANTIBODY COMPLEX; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ARTICLE; CRYSTAL STRUCTURE; EGG; GENE DELETION; GENE MUTATION; HEAVY CHAIN; IMMUNOGLOBULIN VARIABLE REGION; LIGHT CHAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; THERMODYNAMICS; ANIMAL; CHEMISTRY; CHICKEN; GENETICS; IMMUNOLOGY; MUTATION; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTIGEN-ANTIBODY COMPLEX; CHICKENS; CRYSTALLOGRAPHY, X-RAY; EGG PROTEINS; IMMUNOGLOBULIN FRAGMENTS; MURAMIDASE; MUTATION; PROTEIN CONFORMATION; THERMODYNAMICS; TYROSINE;

EID: 34250315356     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M605197200     Document Type: Article

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