Targeting the Achilles heel of the hepatitis B virus: A review of current treatments against covalently closed circular DNA

Drug Discovery Today

Volumn 20, Issue 5, 2015, Pages 548-561

  Ahmed, Marawan ^a   Wang, Feng ^b   Levin, Aviad ^a   Le, Connie ^a   Eltayebi, Yomna ^a   Houghton, Michael ^a,c   Tyrrell, Lorne ^a,c   Barakat, Khaled ^a,c  

^a UNIVERSITY OF ALBERTA   (Canada)

^b SWINBURNE UNIVERSITY OF TECHNOLOGY   (Australia)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; CIRCULAR DNA; VIRUS DNA;

ANIMAL; CHEMICAL STRUCTURE; DRUG DESIGN; DRUG EFFECTS; GENETICS; GENOTYPE; GROWTH, DEVELOPMENT AND AGING; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMAN; MOLECULARLY TARGETED THERAPY; REMISSION; STRUCTURE ACTIVITY RELATION; TREATMENT OUTCOME; VIROLOGY; VIRUS LOAD;

ANIMALS; ANTIVIRAL AGENTS; DNA, CIRCULAR; DNA, VIRAL; DRUG DESIGN; GENOTYPE; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; MOLECULAR STRUCTURE; MOLECULAR TARGETED THERAPY; REMISSION INDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TREATMENT OUTCOME; VIRAL LOAD;

EID: 84939949165     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2015.01.008     Document Type: Review

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