Synthesis and in vitro anti-hepatitis B virus activities of 4-aryl-6-chloro-quinolin-2-one and 5-aryl-7-chloro-1,4-benzodiazepine derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 13, 2008, Pages 3787-3789

  Cheng, Pi ^a,b   Zhang, Quan ^a,b   Ma, Yun Bao ^a   Jiang, Zhi Yong ^a   Zhang, Xue Mei ^a   Zhang, Feng Xue ^c   Chen, Ji Jun ^a  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

4 Aryl 6 chloro quinolin 2 one; 5 Aryl 7 chloro 1,4 benzodiazepine; Anti HBV activity

Indexed keywords

4 ARYL 6 CHLORO QUINOLIN 2 ONE DERIVATIVE; 5 ARYL 7 CHLORO 1,4 BENZODIAZEPINE DERIVATIVE; ANTIVIRUS AGENT; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN;

ANTIVIRAL ACTIVITY; ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOTOXICITY; DRUG DETERMINATION; DRUG STRUCTURE; DRUG SYNTHESIS; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; IC 50;

ANTIVIRAL AGENTS; BENZODIAZEPINES; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; CHLORINE; DRUG DESIGN; HEPATITIS B; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

HEPATITIS B VIRUS;

EID: 44849085438     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.05.065     Document Type: Article

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