Replicative activity of hepatitis B virus is negatively associated with methylation of covalently closed circular DNA in advanced hepatitis B virus infection

Intervirology

Volumn 54, Issue 6, 2011, Pages 316-325

  Kim, Jin Wook ^a,b   Lee, Sang Hyub ^a,b   Park, Young Soo ^a,b   Hwang, Jin Hyeok ^a,b   Jeong, Sook Hyang ^a,b   Kim, Nayoung ^a,b   Lee, Dong Ho ^a,b  

^a Seoul National University Bundang Hospital   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

Author keywords

Covalently closed circular DNA; Hepatitis B virus; Liver cirrhosis; Methylation; Transcription

Indexed keywords

BISULFITE; CIRCULAR DNA; COVALENTLY CLOSED CIRCULAR DNA; HEPATITIS B(E) ANTIGEN; UNCLASSIFIED DRUG; VIRUS DNA;

ADULT; AGED; ARTICLE; BIOCHEMISTRY; CANCER SURGERY; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; FEMALE; GENETIC TRANSCRIPTION; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MALE; PRIORITY JOURNAL; TRANSCRIPTION INITIATION; VIRION; VIRUS REPLICATION;

ADULT; AGED; BASE SEQUENCE; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; CPG ISLANDS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA, CIRCULAR; DNA, VIRAL; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION, VIRAL; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; LIVER CIRRHOSIS; MALE; METHYL-CPG-BINDING PROTEIN 2; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; VIRUS REPLICATION;

HEPATITIS B VIRUS;

EID: 80053994925     PISSN: 03005526     EISSN: 14230100     Source Type: Journal    
DOI: 10.1159/000321450     Document Type: Article

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