-
1
-
-
6944233864
-
-
Available from Accessed October 10, 2005
-
Asian Liver Center at Stanford University. Statistics, 2003. Available from http://livercancer.stanford.edu/index2.asp?lang=eng&page=statistics. Accessed October 10, 2005.
-
(2003)
Statistics
-
-
-
2
-
-
33845361196
-
-
May Available from Accessed October 7, 2005
-
World Health Organization. Disease statistics, May 2005. Available from http://www.who.int/healthinfo/statistics/en. Accessed October 7, 2005.
-
(2005)
Disease Statistics
-
-
-
3
-
-
84888802466
-
-
Available from Accessed October 7, 2005
-
Hepatitis B Foundation. Statistics. Available from http://www.hepb.org/ hepb/statistics.htm. Accessed October 7, 2005.
-
Statistics
-
-
-
4
-
-
33845370234
-
Viral hepatitis
-
DiPiro JT, Talbert RL, Yee GC, et al, eds. New York: McGraw-Hill
-
Pai MP, Mercier RC, Raebel MA. Viral hepatitis. In: DiPiro JT, Talbert RL, Yee GC, et al, eds. Pharmacotherapy: a pathophysiologic approach, 9th ed. New York: McGraw-Hill, 2005:742-51.
-
(2005)
Pharmacotherapy: A Pathophysiologic Approach, 9th Ed.
, pp. 742-751
-
-
Pai, M.P.1
Mercier, R.C.2
Raebel, M.A.3
-
5
-
-
15044361640
-
Viral hepatitis
-
Buccolo LS. Viral hepatitis. Clin Fam Pract 2005;7:105-25.
-
(2005)
Clin Fam Pract
, vol.7
, pp. 105-125
-
-
Buccolo, L.S.1
-
6
-
-
20444453279
-
Drug insight: Nucleoside and nucleotide analog inhibitors for hepatitis B
-
Fung SK, Lok AS. Drug insight: nucleoside and nucleotide analog inhibitors for hepatitis B. Nat Clin Pract Gastroenterol Hepatol 2004;1:90-7.
-
(2004)
Nat Clin Pract Gastroenterol Hepatol
, vol.1
, pp. 90-97
-
-
Fung, S.K.1
Lok, A.S.2
-
7
-
-
33845371936
-
Viral hepatitis
-
Schumock G, Brundage D, Chapman M, et al, eds. Kansas City, MO: American College of Clinical Pharmacy
-
Chan J. Viral hepatitis. In: Schumock G, Brundage D, Chapman M, et al, eds. Pharmacotherapy self-assessment program, 5th ed. Gastroenterology and nutrition. Kansas City, MO: American College of Clinical Pharmacy, 2005:9-13.
-
(2005)
Pharmacotherapy Self-assessment Program, 5th Ed. Gastroenterology and Nutrition
, pp. 9-13
-
-
Chan, J.1
-
9
-
-
23744445119
-
Drugs in development for hepatitis B
-
Buti M, Esteban R. Drugs in development for hepatitis B. Drugs 2005;65:1451-60.
-
(2005)
Drugs
, vol.65
, pp. 1451-1460
-
-
Buti, M.1
Esteban, R.2
-
10
-
-
0141526161
-
Natural history of hepatitis B
-
Fatovich G. Natural history of hepatitis B. J Hepatol 2003;39(suppl 1):S50-8.
-
(2003)
J Hepatol
, vol.39
, Issue.SUPPL. 1
-
-
Fatovich, G.1
-
11
-
-
0036902495
-
Worldwide epidemiology of HBeAg-negative chronic hepatitis B and associated precore and core promoter variants
-
Funk ML, Rosenberg DM, Lok ASF. Worldwide epidemiology of HBeAg-negative chronic hepatitis B and associated precore and core promoter variants. J Viral Hepat 2002;9:52-61.
-
(2002)
J Viral Hepat
, vol.9
, pp. 52-61
-
-
Funk, M.L.1
Rosenberg, D.M.2
Lok, A.S.F.3
-
12
-
-
0035189597
-
AASLD practice guidelines: Chronic hepatitis B
-
American Association for the Study of Liver Disease, December 2003
-
Lok AS, McMahon BJ. AASLD practice guidelines: chronic hepatitis B. American Association for the Study of Liver Disease, December 2003. Hepatology 2001;34:1225-41.
-
(2001)
Hepatology
, vol.34
, pp. 1225-1241
-
-
Lok, A.S.1
McMahon, B.J.2
-
13
-
-
0842304907
-
A treatment algorithm for the management of chronic hepatitis B virus infection in the United States
-
Keefe EB, Dietrich DT, Han SB, et al. A treatment algorithm for the management of chronic hepatitis B virus infection in the United States. Clin Gastroenterol Hepatol 2004;2:87-106.
-
(2004)
Clin Gastroenterol Hepatol
, vol.2
, pp. 87-106
-
-
Keefe, E.B.1
Dietrich, D.T.2
Han, S.B.3
-
14
-
-
8444250990
-
Antiviral therapy for treatment-naive hepatitis B virus patients
-
Lau DT, Membreno FE. Antiviral therapy for treatment-naive hepatitis B virus patients. Gastroenterol Clin North Am 2004;33:581-99.
-
(2004)
Gastroenterol Clin North Am
, vol.33
, pp. 581-599
-
-
Lau, D.T.1
Membreno, F.E.2
-
15
-
-
0003859843
-
-
Centers for Disease Control and Prevention. Available from Accessed October 8, 2005
-
Centers for Disease Control and Prevention. Hepatitis B fact sheet. Available from http://www.hivandhepatitis.com/hep_b/treatment.html. Accessed October 8, 2005.
-
Hepatitis B Fact Sheet
-
-
-
16
-
-
0027998131
-
The treatment effect of alpha-interferon in chronic hepatitis B is independent of pre-treatment variables: Results based on individual patient data from 10 clinical controlled trials. European concerted action on viral hepatitis (EUROHEP)
-
Krogsgaard K, Bindslev N, Christensen E, et al. The treatment effect of alpha-interferon in chronic hepatitis B is independent of pre-treatment variables: results based on individual patient data from 10 clinical controlled trials. European concerted action on viral hepatitis (EUROHEP). J Hepatol 1994;21:646-55.
-
(1994)
J Hepatol
, vol.21
, pp. 646-655
-
-
Krogsgaard, K.1
Bindslev, N.2
Christensen, E.3
-
17
-
-
33845362785
-
Interferon
-
Hudson, OH: Lexi-Comp
-
Lacy CF, Armstrong LL, Goldman MP, et al. Interferon. In: Lexi-Comp's drug information handbook, 13th ed. Hudson, OH: Lexi-Comp, 2005:811-15.
-
(2005)
Lexi-Comp's Drug Information Handbook, 13th Ed.
, pp. 811-815
-
-
Lacy, C.F.1
Armstrong, L.L.2
Goldman, M.P.3
-
18
-
-
0038045171
-
Peginterferon alpha-2a (40 kDa): An advance in the treatment of hepatitis B e antigen-positive chronic hepatitis B
-
Cooksley WG, Piratvisuth T, Lee SD, et al. Peginterferon alpha-2a (40 kDa): an advance in the treatment of hepatitis B e antigen-positive chronic hepatitis B. J Viral Hepat 2003;10:298-305.
-
(2003)
J Viral Hepat
, vol.10
, pp. 298-305
-
-
Cooksley, W.G.1
Piratvisuth, T.2
Lee, S.D.3
-
19
-
-
19944428132
-
Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: A randomized trial
-
Janssen HL, van Zonneveld M, Senturk H, et al. Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomized trial. Lancet 2005;365:123-9.
-
(2005)
Lancet
, vol.365
, pp. 123-129
-
-
Janssen, H.L.1
Van Zonneveld, M.2
Senturk, H.3
-
20
-
-
21244447705
-
Peginterferon alfa-2a, lamivudine, and the combination for HBe-Ag-positive chronic hepatitis B
-
Lau GK, Piratvisuth T, Luo KX, et al. Peginterferon alfa-2a, lamivudine, and the combination for HBe-Ag-positive chronic hepatitis B. N Engl J Med 2005;352:2682-95.
-
(2005)
N Engl J Med
, vol.352
, pp. 2682-2695
-
-
Lau, G.K.1
Piratvisuth, T.2
Luo, K.X.3
-
21
-
-
4544239807
-
Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B
-
Marcellin P, Lau GK, Bonino F, et al. Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B. N Engl J Med 2004;351:1206-17.
-
(2004)
N Engl J Med
, vol.351
, pp. 1206-1217
-
-
Marcellin, P.1
Lau, G.K.2
Bonino, F.3
-
22
-
-
20344383740
-
Management of patients co-infected with hepatitis B virus and HIV
-
Nunez M, Soriano V. Management of patients co-infected with hepatitis B virus and HIV. Lancet Infect Dis 2005;5:374-82.
-
(2005)
Lancet Infect Dis
, vol.5
, pp. 374-382
-
-
Nunez, M.1
Soriano, V.2
-
23
-
-
25144478957
-
Gastroenterology expert column: The role of interferon therapy in hepatitis B
-
Cooksley WG. Gastroenterology expert column: the role of interferon therapy in hepatitis B. Med Gen Med 2004;6:16-21.
-
(2004)
Med Gen Med
, vol.6
, pp. 16-21
-
-
Cooksley, W.G.1
-
24
-
-
0029591574
-
A preliminary study of lamivudine for chronic hepatitis B infection
-
Dienstag JL, Schiff ER, Wright TL. A preliminary study of lamivudine for chronic hepatitis B infection. N Engl J Med 1995;333:1657-61.
-
(1995)
N Engl J Med
, vol.333
, pp. 1657-1661
-
-
Dienstag, J.L.1
Schiff, E.R.2
Wright, T.L.3
-
25
-
-
33748095099
-
-
GlaxoSmithKline. Research Triangle Park, NC
-
GlaxoSmithKline. Epivir-HBV (lamivudine) package insert. Research Triangle Park, NC; 2004.
-
(2004)
Epivir-HBV (Lamivudine) Package Insert
-
-
-
26
-
-
0033592764
-
Lamivudine as initial treatment for chronic hepatitis B in the United States
-
Dienstag JL, Schiff ER, Wright TL, et al. Lamivudine as initial treatment for chronic hepatitis B in the United States. N Engl J Med 1999;341:1256-63.
-
(1999)
N Engl J Med
, vol.341
, pp. 1256-1263
-
-
Dienstag, J.L.1
Schiff, E.R.2
Wright, T.L.3
-
27
-
-
0034105307
-
Lamivudine and alpha-interferon combination treatment of patients with chronic hepatitis B infection: A randomized trial
-
Schalm SW, Heathcote J, Cianciara J, et al. Lamivudine and alpha-interferon combination treatment of patients with chronic hepatitis B infection: a randomized trial. Gut 2000;46:562-8.
-
(2000)
Gut
, vol.46
, pp. 562-568
-
-
Schalm, S.W.1
Heathcote, J.2
Cianciara, J.3
-
28
-
-
0032499913
-
A one-year trial of lamivudine for chronic hepatitis B: Asia hepatitis lamivudine study group
-
Lai CL, Chien RN, Leung NW, et al. A one-year trial of lamivudine for chronic hepatitis B: Asia hepatitis lamivudine study group. N Engl J Med 1998;339:61-8.
-
(1998)
N Engl J Med
, vol.339
, pp. 61-68
-
-
Lai, C.L.1
Chien, R.N.2
Leung, N.W.3
-
29
-
-
0033012793
-
Efficacy of lamivudine in patients with hepatitis B e antigen-negative/hepatitis B virus DNA-positive (precore mutant) chronic hepatitis B: Lamivudine precore mutant study group
-
Tassopoulos NC, Volpes R, Pastore G, et al. Efficacy of lamivudine in patients with hepatitis B e antigen-negative/hepatitis B virus DNA-positive (precore mutant) chronic hepatitis B: lamivudine precore mutant study group. Hepatology 1999;29:889-96.
-
(1999)
Hepatology
, vol.29
, pp. 889-896
-
-
Tassopoulos, N.C.1
Volpes, R.2
Pastore, G.3
-
30
-
-
0033797827
-
Hepatitis B e antigen seroconversion after lamivudine therapy is not durable in patients with chronic hepatitis B in Korea
-
Song BC, Suh DJ, Lee HC, et al. Hepatitis B e antigen seroconversion after lamivudine therapy is not durable in patients with chronic hepatitis B in Korea. Hepatology 2000;32:803-6.
-
(2000)
Hepatology
, vol.32
, pp. 803-806
-
-
Song, B.C.1
Suh, D.J.2
Lee, H.C.3
-
31
-
-
0034235528
-
Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B
-
Liaw YF, Leung NWY, Chang TT, et al. Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B. Gastroenterology 2000;119:172-80.
-
(2000)
Gastroenterology
, vol.119
, pp. 172-180
-
-
Liaw, Y.F.1
Leung, N.W.Y.2
Chang, T.T.3
-
32
-
-
0002443164
-
Incremental increases in HBeAg seroconversion and continued ALT normalization in Asian chronic HBV (CHB) patients treated with lamivudine for four years
-
[abstr]
-
Chang TT, Lai CL, Liaw YF, et al. Incremental increases in HBeAg seroconversion and continued ALT normalization in Asian chronic HBV (CHB) patients treated with lamivudine for four years [abstr]. Antiviral Ther 2000;5(suppl 1):44.
-
(2000)
Antiviral Ther
, vol.5
, Issue.SUPPL. 1
, pp. 44
-
-
Chang, T.T.1
Lai, C.L.2
Liaw, Y.F.3
-
33
-
-
0034993211
-
Extended lamivudine treatment in patients with chronic hepatitis B enhances hepatitis B e antigen seroconversion rates: Results after 3 years of therapy
-
Leung NWY, Lai CL, Chang TT, et al. Extended lamivudine treatment in patients with chronic hepatitis B enhances hepatitis B e antigen seroconversion rates: results after 3 years of therapy. Hepatology 2001;33:1527-32.
-
(2001)
Hepatology
, vol.33
, pp. 1527-1532
-
-
Leung, N.W.Y.1
Lai, C.L.2
Chang, T.T.3
-
34
-
-
0000470655
-
Postlamivudine treatment follow-up patients with HBeAg negative chronic hepatitis B
-
[abstr]
-
Tassopoulos NC, Volpes R, Pastore G, et al. Postlamivudine treatment follow-up patients with HBeAg negative chronic hepatitis B [abstr]. J Hepatol 1999;30(suppl 1):117.
-
(1999)
J Hepatol
, vol.30
, Issue.SUPPL. 1
, pp. 117
-
-
Tassopoulos, N.C.1
Volpes, R.2
Pastore, G.3
-
35
-
-
0032783679
-
Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy
-
Liaw YF, Chien RN, Yeh CT, Tsai SL, Chu CM. Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy. Hepatology 1999;30:567-72.
-
(1999)
Hepatology
, vol.30
, pp. 567-572
-
-
Liaw, Y.F.1
Chien, R.N.2
Yeh, C.T.3
Tsai, S.L.4
Chu, C.M.5
-
37
-
-
0029817898
-
Mutation in HBV RNA dependent DNA polymerase confers resistance to lamivudine in vivo
-
Tipples GA, Ma MM, Fischer KP, Bain VG, Kneteman NM, Tyrell DL. Mutation in HBV RNA dependent DNA polymerase confers resistance to lamivudine in vivo. Hepatology 1996;24:714-17.
-
(1996)
Hepatology
, vol.24
, pp. 714-717
-
-
Tipples, G.A.1
Ma, M.M.2
Fischer, K.P.3
Bain, V.G.4
Kneteman, N.M.5
Tyrell, D.L.6
-
38
-
-
0003134396
-
Efficacy and safety of 5-years lamivudine treatment of Chinese patients with chronic hepatitis B
-
[abstr]
-
Guan R, Lai CL, Liaw YF, Lim SG, Lee CM. Efficacy and safety of 5-years lamivudine treatment of Chinese patients with chronic hepatitis B [abstr]. J Gastroenterol Hepatol 2001;16(suppl 1):A60.
-
(2001)
J Gastroenterol Hepatol
, vol.16
, Issue.SUPPL. 1
-
-
Guan, R.1
Lai, C.L.2
Liaw, Y.F.3
Lim, S.G.4
Lee, C.M.5
-
41
-
-
0037468421
-
Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B
-
Marcellin P, Chang TT, Lim SG, et al. Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. N Engl J Med 2003;348:808-16.
-
(2003)
N Engl J Med
, vol.348
, pp. 808-816
-
-
Marcellin, P.1
Chang, T.T.2
Lim, S.G.3
-
42
-
-
0037468406
-
Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B
-
Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B. N Engl J Med 2003;348:801-7.
-
(2003)
N Engl J Med
, vol.348
, pp. 801-807
-
-
Hadziyannis, S.J.1
Tassopoulos, N.C.2
Heathcote, E.J.3
-
43
-
-
0142090238
-
Two year results from a double-blind, randomized, placebo-controlled study of adefovir dipivoxil (ADV) for presumed precore mutant chronic hepatitis B
-
[abstr]
-
Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. Two year results from a double-blind, randomized, placebo-controlled study of adefovir dipivoxil (ADV) for presumed precore mutant chronic hepatitis B [abstr]. J Hepatol 2003;38:S143.
-
(2003)
J Hepatol
, vol.38
-
-
Hadziyannis, S.J.1
Tassopoulos, N.C.2
Heathcote, E.J.3
-
44
-
-
0034897595
-
Adefovir nephrotoxicity: Possible role of mitochondrial DNA depletion
-
Tanji N, Tanji K, Kambham N, Markowitz GS, Bell A, D'agati VD. Adefovir nephrotoxicity: possible role of mitochondrial DNA depletion. Hum Pathol 2001;32:734-40.
-
(2001)
Hum Pathol
, vol.32
, pp. 734-740
-
-
Tanji, N.1
Tanji, K.2
Kambham, N.3
Markowitz, G.S.4
Bell, A.5
D'Agati, V.D.6
-
45
-
-
4444227410
-
Three year study of adefovir dipivoxil demonstrates sustained efficacy in presumed precore mutant chronic hepatitis B (CHB) patients in a long term safety and efficacy study (LTSES)
-
[abstr]
-
Hadziyannis SJ, Tassopoulos NC, Chang TT, et al. Three year study of adefovir dipivoxil demonstrates sustained efficacy in presumed precore mutant chronic hepatitis B (CHB) patients in a long term safety and efficacy study (LTSES) [abstr]. J Hepatol 2004;40:17.
-
(2004)
J Hepatol
, vol.40
, pp. 17
-
-
Hadziyannis, S.J.1
Tassopoulos, N.C.2
Chang, T.T.3
-
46
-
-
21244455293
-
Long term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B
-
Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. Long term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B. N Engl J Med 2005;352:2673-81.
-
(2005)
N Engl J Med
, vol.352
, pp. 2673-2681
-
-
Hadziyannis, S.J.1
Tassopoulos, N.C.2
Heathcote, E.J.3
-
47
-
-
0031761652
-
In vitro inhibition of hepadnavirus polymerase by the triphosphates of BMS-200475 and lobucavir
-
Seifer M, Hamatake RK, Colonno RJ. In vitro inhibition of hepadnavirus polymerase by the triphosphates of BMS-200475 and lobucavir. Antimicrob Agents Chemother 1998;42:3200-8.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 3200-3208
-
-
Seifer, M.1
Hamatake, R.K.2
Colonno, R.J.3
-
48
-
-
0032907705
-
Metabolic studies on BMS-200475, a new antiviral compound active against hepatitis B virus
-
Yamanaka G, Wilson T, Innaimo S, et al. Metabolic studies on BMS-200475, a new antiviral compound active against hepatitis B virus. Antimicrob Agents Chemother 1999;43:190-3.
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 190-193
-
-
Yamanaka, G.1
Wilson, T.2
Innaimo, S.3
-
49
-
-
24344436307
-
Clinical trial results of new therapies for HBV: Implications for treatment guidelines
-
Gish RG. Clinical trial results of new therapies for HBV: implications for treatment guidelines. Semin Liver Dis 2005;25(suppl 1):29-39.
-
(2005)
Semin Liver Dis
, vol.25
, Issue.SUPPL. 1
, pp. 29-39
-
-
Gish, R.G.1
-
50
-
-
0037398391
-
Entecavir, a potent new antiviral drug for hepatitis B
-
Honkoop P, deMan RA. Entecavir, a potent new antiviral drug for hepatitis B. Expert Opin Investig Drugs 2003;12:638-88.
-
(2003)
Expert Opin Investig Drugs
, vol.12
, pp. 638-688
-
-
Honkoop, P.1
DeMan, R.A.2
-
51
-
-
0030872946
-
Identification of BMS-200475 as a potent and selective inhibitor of hepatitis B virus
-
Innaimo SF, Siefer M, Bisacchi GS, et al. Identification of BMS-200475 as a potent and selective inhibitor of hepatitis B virus. Antimicrob Agents Chemother 1999;41:1444-8.
-
(1999)
Antimicrob Agents Chemother
, vol.41
, pp. 1444-1448
-
-
Innaimo, S.F.1
Siefer, M.2
Bisacchi, G.S.3
-
52
-
-
24344444416
-
Current treatment of chronic hepatitis B: Benefits and limitations
-
Perrillo RP. Current treatment of chronic hepatitis B: benefits and limitations. Semin Liver Dis 2005;25:S20-8.
-
(2005)
Semin Liver Dis
, vol.25
-
-
Perrillo, R.P.1
-
53
-
-
2942534508
-
Molecular virology of hepatitis B virus
-
Locarnini S. Molecular virology of hepatitis B virus. Semin Liver Dis 2004;24:3-10.
-
(2004)
Semin Liver Dis
, vol.24
, pp. 3-10
-
-
Locarnini, S.1
-
55
-
-
33845355052
-
-
Effects of renal impairment on single-dose pharmacokinetics of entecavir. Presented as a poster at the Paris, France, April 13-17
-
Yan JH, Bifano M, Xie J, et al. Effects of renal impairment on single-dose pharmacokinetics of entecavir. Presented as a poster at the 40th annual meeting of the European association of the study of the liver. Paris, France, April 13-17, 2005.
-
(2005)
40th Annual Meeting of the European Association of the Study of the Liver
-
-
Yan, J.H.1
Bifano, M.2
Xie, J.3
-
56
-
-
33845349889
-
-
Hepatic impairment does not alter single-dose pharmacokinetics and safety of entecavir. Presented as a poster at the Boston, MA, October 29-November 2
-
Bifano M, Yan JH, Xia J, et al. Hepatic impairment does not alter single-dose pharmacokinetics and safety of entecavir. Presented as a poster at the 55th annual meeting of the American association for the study of liver diseases. Boston, MA, October 29-November 2, 2004.
-
(2004)
55th Annual Meeting of the American Association for the Study of Liver Diseases
-
-
Bifano, M.1
Yan, J.H.2
Xia, J.3
-
57
-
-
0031728652
-
Efficacy of the carbocyclic 2′-deoxyguanosine nucleoside BMS-200475 in the woodchuck model of hepatitis B virus infection
-
Genovesi EV, Lamb L, Medina I, et al. Efficacy of the carbocyclic 2′-deoxyguanosine nucleoside BMS-200475 in the woodchuck model of hepatitis B virus infection. Antimicrob Agents Chemother 1998;42:3209-17.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 3209-3217
-
-
Genovesi, E.V.1
Lamb, L.2
Medina, I.3
-
58
-
-
0042632899
-
Characterization of antiviral activity of entecavir in transgenic mice expressing hepatitis B virus
-
Julander JG, Colonno RJ, Sidwell RW, Morrey JD. Characterization of antiviral activity of entecavir in transgenic mice expressing hepatitis B virus. Antivir Res 2003;59:155-61.
-
(2003)
Antivir Res
, vol.59
, pp. 155-161
-
-
Julander, J.G.1
Colonno, R.J.2
Sidwell, R.W.3
Morrey, J.D.4
-
60
-
-
0035890097
-
Long-term entecavir treatment results in sustained antiviral efficacy and prolonged life span in the woodchuck model of chronic hepatitis infection
-
Colonno RJ, Genovesi EV, Medina I, et al. Long-term entecavir treatment results in sustained antiviral efficacy and prolonged life span in the woodchuck model of chronic hepatitis infection. J Infect Dis 2001;184:1236-45.
-
(2001)
J Infect Dis
, vol.184
, pp. 1236-1245
-
-
Colonno, R.J.1
Genovesi, E.V.2
Medina, I.3
-
61
-
-
0025329760
-
In hepatocytes infected with duck hepatitis B virus, the template for RNA synthesis is amplified by an intracellular conversion pathway
-
Wu TT, Coates L, Aldrich CE, Summers J, Mason WS. In hepatocytes infected with duck hepatitis B virus, the template for RNA synthesis is amplified by an intracellular conversion pathway Virology 1990;175:255-61.
-
(1990)
Virology
, vol.175
, pp. 255-261
-
-
Wu, T.T.1
Coates, L.2
Aldrich, C.E.3
Summers, J.4
Mason, W.S.5
-
62
-
-
0030776176
-
Lack of effect of antiviral therapy in nondividing hepatocyte cultures on the closed circular DNA of woodchuck hepatitis B virus
-
Moraleda G, Spautelli J, Aldrich CE, Averett D, Condreay L, Mason W. Lack of effect of antiviral therapy in nondividing hepatocyte cultures on the closed circular DNA of woodchuck hepatitis B virus. J Virol 1997;71:9392-9.
-
(1997)
J Virol
, vol.71
, pp. 9392-9399
-
-
Moraleda, G.1
Spautelli, J.2
Aldrich, C.E.3
Averett, D.4
Condreay, L.5
Mason, W.6
-
63
-
-
0032838507
-
Use of hepatitis B virus recombinant baculovirus-HepG2 system to study the effects of (-)-β-2′-3′-dideoxy-3′-thiacytidine on the replication of hepatitis B virus and accumulation of covalently closed circular DNA
-
Delaney W, Miller T, Isom HC. Use of hepatitis B virus recombinant baculovirus-HepG2 system to study the effects of (-)-β-2′-3′- dideoxy-3′-thiacytidine on the replication of hepatitis B virus and accumulation of covalently closed circular DNA. Antimicrob Agents Chem 1999;43:2017-26.
-
(1999)
Antimicrob Agents Chem
, vol.43
, pp. 2017-2026
-
-
Delaney, W.1
Miller, T.2
Isom, H.C.3
-
64
-
-
0034867425
-
Safety and efficacy of oral entecavir given for 28 days in patients with chronic hepatitis B virus infection
-
DeMan RA, Wolters LM, Nevens F, et al. Safety and efficacy of oral entecavir given for 28 days in patients with chronic hepatitis B virus infection. Hepatology 2001;34:578-82.
-
(2001)
Hepatology
, vol.34
, pp. 578-582
-
-
DeMan, R.A.1
Wolters, L.M.2
Nevens, F.3
-
65
-
-
0036892435
-
Entecavir is superior to lamivudine in reducing hepatitis B virus DNA in patients with chronic hepatitis B infection
-
Lai CL, Rosmawati M, Lao J, et al. Entecavir is superior to lamivudine in reducing hepatitis B virus DNA in patients with chronic hepatitis B infection. Gastroenterology 2002;123:1831-8.
-
(2002)
Gastroenterology
, vol.123
, pp. 1831-1838
-
-
Lai, C.L.1
Rosmawati, M.2
Lao, J.3
-
66
-
-
26844500312
-
A dose-ranging study of the efficacy and tolerability of entecavir in lamivudine-refractory chronic hepatitis B patients
-
Chang TT, Gish RG, Hadziyannis SJ, et al. A dose-ranging study of the efficacy and tolerability of entecavir in lamivudine-refractory chronic hepatitis B patients. Gastroenterology 2005;129:1198-209.
-
(2005)
Gastroenterology
, vol.129
, pp. 1198-1209
-
-
Chang, T.T.1
Gish, R.G.2
Hadziyannis, S.J.3
-
67
-
-
33644818518
-
A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B
-
Chang TT, Gish R, de Man R, et al. A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N Engl J Med 2006;354:1001-10.
-
(2006)
N Engl J Med
, vol.354
, pp. 1001-1010
-
-
Chang, T.T.1
Gish, R.2
De Man, R.3
-
68
-
-
33644822860
-
Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B
-
Lai CL, Shouval D, Lok AS, et al. Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B. N Engl Med 2006;354:1011-20.
-
(2006)
N Engl Med
, vol.354
, pp. 1011-1020
-
-
Lai, C.L.1
Shouval, D.2
Lok, A.S.3
-
69
-
-
9944243414
-
Entecavir is superior to continued lamivudine for the treatment of lamivudine-refractory, HBeAg(+) chronic hepatitis B: Results of phase III study ETV-026
-
[abstr]
-
Sherman M, Yurdaydin C, Sollano J, et al. Entecavir is superior to continued lamivudine for the treatment of lamivudine-refractory, HBeAg(+) chronic hepatitis B: results of phase III study ETV-026 [abstr]. Hepatology 2004;40:664A.
-
(2004)
Hepatology
, vol.40
-
-
Sherman, M.1
Yurdaydin, C.2
Sollano, J.3
-
70
-
-
9144271733
-
Adefovir dipivoxil alone or in combination with lamivudine in patients with lamivudine-resistant chronic hepatitis B
-
Peters MG, Hann HWH, Martin P, et al. Adefovir dipivoxil alone or in combination with lamivudine in patients with lamivudine-resistant chronic hepatitis B. Gastroenterology 2004;1261:91-101.
-
(2004)
Gastroenterology
, vol.1261
, pp. 91-101
-
-
Peters, M.G.1
Hann, H.W.H.2
Martin, P.3
-
71
-
-
9144234192
-
Adefovir dipivoxil added to ongoing lamivudine in chronic hepatitis B with YMDD mutant hepatitis B virus
-
Perrillo R, Hann HW, Mutimer D, et al. Adefovir dipivoxil added to ongoing lamivudine in chronic hepatitis B with YMDD mutant hepatitis B virus. Gastroenterology 2004;126:81-90.
-
(2004)
Gastroenterology
, vol.126
, pp. 81-90
-
-
Perrillo, R.1
Hann, H.W.2
Mutimer, D.3
-
72
-
-
0344364590
-
Adefovir dipivoxil therapy for lamivudine-resistant hepatitis B in pre- and post-liver transplantation patients
-
Schiff ER, Lai CL, Hadziyannis S, et al. Adefovir dipivoxil therapy for lamivudine-resistant hepatitis B in pre- and post-liver transplantation patients. Hepatology 2003;38:1419-27.
-
(2003)
Hepatology
, vol.38
, pp. 1419-1427
-
-
Schiff, E.R.1
Lai, C.L.2
Hadziyannis, S.3
-
73
-
-
0003979206
-
-
Bristol-Myers Squibb Co. Princeton, NJ
-
Bristol-Myers Squibb Co. Data on file. Princeton, NJ; 2005.
-
(2005)
Data on File
-
-
-
74
-
-
9944263858
-
Emergence of entecavir resistant hepatitis B virus after one year of therapy in phase II and III studies is only observed in lamivudine refractory patients
-
[abstr]
-
Colonno RJ, Rose RE, Levine SM, et al. Emergence of entecavir resistant hepatitis B virus after one year of therapy in phase II and III studies is only observed in lamivudine refractory patients [abstr]. Hepatology 2004;40:661A.
-
(2004)
Hepatology
, vol.40
-
-
Colonno, R.J.1
Rose, R.E.2
Levine, S.M.3
-
75
-
-
4344627233
-
Clinical emergence of entecavir-resistant hepatitis B virus requires additional substitutions in virus already resistant to lamivudine
-
Tenney DJ, Levine SM, Rose RE, et al. Clinical emergence of entecavir-resistant hepatitis B virus requires additional substitutions in virus already resistant to lamivudine. Antimicrob Agents Chemother 2004;48:3498-507.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 3498-3507
-
-
Tenney, D.J.1
Levine, S.M.2
Rose, R.E.3
-
76
-
-
33845363735
-
-
Entecavir (ETV) resistance is not observed in nucleoside naïve subjects and is observed infrequently by week 48 in lamivudine-refractory subjects with chronic HBV infection. Presented as a poster at the Paris, France, April 13-17
-
Colonno RJ, Rose RE, Levine SM, et al. Entecavir (ETV) resistance is not observed in nucleoside naïve subjects and is observed infrequently by week 48 in lamivudine-refractory subjects with chronic HBV infection. Presented as a poster at the 40th annual meeting of the European association of the study of the liver, Paris, France, April 13-17, 2005.
-
(2005)
40th Annual Meeting of the European Association of the Study of the Liver
-
-
Colonno, R.J.1
Rose, R.E.2
Levine, S.M.3
-
77
-
-
4444349857
-
In vitro characterization and molecular modeling analysis of a novel adefovir resistance mutation rtN236T in the HBV polymerase
-
[abstr]
-
Yang H, Qi X, Das K, et al. In vitro characterization and molecular modeling analysis of a novel adefovir resistance mutation rtN236T in the HBV polymerase [abstr]. J Hepatol 2004;40:A383.
-
(2004)
J Hepatol
, vol.40
-
-
Yang, H.1
Qi, X.2
Das, K.3
-
78
-
-
20244373332
-
Hepatitis B and HIV: Prevalence, AIDS progression, response to highly active antiretroviral therapy and increased mortality in the EuroSIDA cohort
-
Konopnicki D, Mocroft A, de Wit S, et al. Hepatitis B and HIV: prevalence, AIDS progression, response to highly active antiretroviral therapy and increased mortality in the EuroSIDA cohort. AIDS 2005;19:593-601.
-
(2005)
AIDS
, vol.19
, pp. 593-601
-
-
Konopnicki, D.1
Mocroft, A.2
De Wit, S.3
-
79
-
-
15844363359
-
The epidemiology and natural history of HIV/HBV and HIV/HCV co-infections
-
Mathews G, Bhagani S. The epidemiology and natural history of HIV/HBV and HIV/HCV co-infections. J HIV Ther 2003;8:77-84.
-
(2003)
J HIV Ther
, vol.8
, pp. 77-84
-
-
Mathews, G.1
Bhagani, S.2
-
80
-
-
33845364498
-
-
Entecavir in HIV/HBV-co-infected patients: safety and efficacy in a phase II study. Presented as a poster at the Boston, MA, February 22-25
-
Pessoa W, Gazzard B, Huang A, et al. Entecavir in HIV/HBV-co-infected patients: safety and efficacy in a phase II study. Presented as a poster at the 12th conference on retroviruses and opportunistic infections, Boston, MA, February 22-25, 2005.
-
(2005)
12th Conference on Retroviruses and Opportunistic Infections
-
-
Pessoa, W.1
Gazzard, B.2
Huang, A.3
-
81
-
-
9944241572
-
Entecavir is well tolerated for treatment of chronic hepatitis B: Phase III safety analysis in nucleoside-naïve and lamivudine-refractory patients
-
[abstr]
-
Sollano J, Schiff E, Carrilho F, et al. Entecavir is well tolerated for treatment of chronic hepatitis B: phase III safety analysis in nucleoside-naïve and lamivudine-refractory patients [abstr]. Hepatology 2004;40:655A.
-
(2004)
Hepatology
, vol.40
-
-
Sollano, J.1
Schiff, E.2
Carrilho, F.3
-
82
-
-
33845352261
-
-
Entecavir is well tolerated for the treatment of nucleoside-naïve and lamivudine-refractory chronic hepatitis B patients: phase II/III safety results. Presented as a poster at the Paris, France, April 13-17
-
Manns MP, Raptopoulou-Gigi M, Sollano J, et al. Entecavir is well tolerated for the treatment of nucleoside-naïve and lamivudine-refractory chronic hepatitis B patients: phase II/III safety results. Presented as a poster at the 40th annual meeting of the European association of the study of the liver, Paris, France, April 13-17, 2005.
-
(2005)
40th Annual Meeting of the European Association of the Study of the Liver
-
-
Manns, M.P.1
Raptopoulou-Gigi, M.2
Sollano, J.3
-
83
-
-
33845363873
-
-
Lack of pharmacokinetic interaction when entecavir is co-administered with lamivudine, adefovir, or tenofovir. Presented as a poster at the Paris France, April 13-17
-
Bifano M, Yan JH, Xie J, et al. Lack of pharmacokinetic interaction when entecavir is co-administered with lamivudine, adefovir, or tenofovir. Presented as a poster at the 40th annual meeting of the European association of the study of the liver, Paris France, April 13-17, 2005.
-
(2005)
40th Annual Meeting of the European Association of the Study of the Liver
-
-
Bifano, M.1
Yan, J.H.2
Xie, J.3
-
84
-
-
33845370354
-
-
Murray L, ed. Montvale, NJ: Thompson PDR, 38
-
Murray L, ed. Red book update. Montvale, NJ: Thompson PDR, 2006;25:20, 38.
-
(2006)
Red Book Update
, vol.25
, pp. 20
-
-
-
85
-
-
33845351033
-
-
Murray L, ed. Montvale, NJ: Thompson PDR, 417, 440, 541
-
Murray L, ed. Red book: pharmacy fundamental reference. Montvale, NJ: Thompson PDR, 2005:370, 417, 440, 541.
-
(2005)
Red Book: Pharmacy Fundamental Reference
, pp. 370
-
-
-
86
-
-
75849124774
-
-
Available from Accessed May 23, 2006
-
Clinical trials.gov. Clinical trials. Available from www.clinicaltrials. gov. Accessed May 23, 2006.
-
Clinical Trials
-
-
-
87
-
-
75849124774
-
-
Available from Accessed May 22, 2006
-
Liver Foundation. Clinical trials. Available from www.liverfoundation. org/db-list/clinicaltrials/1/ascend/ID/Validated. Accessed May 22, 2006.
-
Clinical Trials
-
-
|