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Volumn 2015, Issue , 2015, Pages

N-3 polyunsaturated fatty acids and inflammation in obesity: Local effect and systemic benefit

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; G PROTEIN COUPLED RECEPTOR 120; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MEMBRANE PHOSPHOLIPID; OMEGA 3 FATTY ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; FAT INTAKE;

EID: 84939482671     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/581469     Document Type: Review
Times cited : (61)

References (152)
  • 1
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • H. Xu, G. T. Barnes, Q. Yang et al. , "Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance, "The Journal of Clinical Investigation, vol. 112, no. 12, pp. 1821-1830, 2003.
    • (2003) The Journal of Clinical Investigation , vol.112 , Issue.12 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3
  • 2
    • 0347985272 scopus 로고    scopus 로고
    • Obesity-induced inflammatory changes in adipose tissue
    • K. E. Wellen and G. S. Hotamisligil, "Obesity-induced inflammatory changes in adipose tissue, " The Journal of Clinical Investigation, vol. 112, no. 12, pp. 1785-1788, 2003.
    • (2003) The Journal of Clinical Investigation , vol.112 , Issue.12 , pp. 1785-1788
    • Wellen, K.E.1    Hotamisligil, G.S.2
  • 3
    • 84907321291 scopus 로고    scopus 로고
    • The role of adipose tissue immune cells in obesity and low-grade inflammation
    • M. Mraz and M. Haluzik, "The role of adipose tissue immune cells in obesity and low-grade inflammation, " Journal of Endocrinology, vol. 222, no. 3, pp. R113-R127, 2014.
    • (2014) Journal of Endocrinology , vol.222 , Issue.3 , pp. R113-R127
    • Mraz, M.1    Haluzik, M.2
  • 4
    • 84892727198 scopus 로고    scopus 로고
    • What we talk about when we talk about fat
    • E. D. Rosen and B. M. Spiegelman, "What we talk about when we talk about fat, " Cell, vol. 156, no. 1-2, pp. 20-44, 2014.
    • (2014) Cell , vol.156 , Issue.1-2 , pp. 20-44
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 5
    • 79957920754 scopus 로고    scopus 로고
    • Inflammatory links between obesity and metabolic disease
    • C. N. Lumeng and A. R. Saltiel, "Inflammatory links between obesity and metabolic disease, "The Journal of Clinical Investigation, vol. 121, no. 6, pp. 2111-2117, 2011.
    • (2011) The Journal of Clinical Investigation , vol.121 , Issue.6 , pp. 2111-2117
    • Lumeng, C.N.1    Saltiel, A.R.2
  • 6
    • 33746830525 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases
    • P. C. Calder, "n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases, " The American Journal of Clinical Nutrition, vol. 83, no. 6, supplement, pp. 1505S-1519S, 2006.
    • (2006) The American Journal of Clinical Nutrition , vol.83 , Issue.6 , pp. 1505S-1519S
    • Calder, P.C.1
  • 7
    • 0036931477 scopus 로고    scopus 로고
    • Omega-3 fatty acids in inflammation and autoimmune diseases
    • A. P. Simopoulos, "Omega-3 fatty acids in inflammation and autoimmune diseases, " The Journal of the American College of Nutrition, vol. 21, no. 6, pp. 495-505, 2002.
    • (2002) The Journal of the American College of Nutrition , vol.21 , Issue.6 , pp. 495-505
    • Simopoulos, A.P.1
  • 8
    • 62249126616 scopus 로고    scopus 로고
    • Duration of feeding linseed diet influences expression of inflammation-related genes and growth performance of growing-finishing barrows
    • Z. P. Zhan, F. R. Huang, J. Luo, J. J. Dai, X. H. Yan, and J. Peng, "Duration of feeding linseed diet influences expression of inflammation-related genes and growth performance of growing-finishing barrows, " Journal of Animal Science, vol. 87, no. 2, pp. 603-611, 2009.
    • (2009) Journal of Animal Science , vol.87 , Issue.2 , pp. 603-611
    • Zhan, Z.P.1    Huang, F.R.2    Luo, J.3    Dai, J.J.4    Yan, X.H.5    Peng, J.6
  • 9
    • 44349112305 scopus 로고    scopus 로고
    • Adipocyte-derived Th2 cytokines and myeloid PPARδ regulate macrophage polarizatioNandinsulin sensitivity
    • K. Kang, S. M. Reilly, V. Karabacak et al. , "Adipocyte-derived Th2 cytokines and myeloid PPARδ regulate macrophage polarizatioNandinsulin sensitivity, " CellMetabolism, vol. 7, no. 6, pp. 485-495, 2008.
    • (2008) Cel LMetabolism , vol.7 , Issue.6 , pp. 485-495
    • Kang, K.1    Reilly, S.M.2    Karabacak, V.3
  • 10
    • 0028931724 scopus 로고
    • Increased adipose tissue expression of tumor necrosis factor-κin human obesity and insulin resistance
    • G. S. Hotamisligil, P. Arner, J. F. Caro, R. L. Atkinson, and B. M. Spiegelman, "Increased adipose tissue expression of tumor necrosis factor-κin human obesity and insulin resistance, " The Journal of Clinical Investigation, vol. 95, no. 5, pp. 2409-2415, 1995.
    • (1995) The Journal of Clinical Investigation , vol.95 , Issue.5 , pp. 2409-2415
    • Hotamisligil, G.S.1    Arner, P.2    Caro, J.F.3    Atkinson, R.L.4    Spiegelman, B.M.5
  • 12
    • 33745896155 scopus 로고    scopus 로고
    • Recent advances in the relationship between obesity, inflammation, and insulin resistance
    • J.-P. Bastard, M. Maachi, C. Lagathu et al. , "Recent advances in the relationship between obesity, inflammation, and insulin resistance, " European Cytokine Network, vol. 17, no. 1, pp. 4-12, 2006.
    • (2006) European Cytokine Network , vol.17 , Issue.1 , pp. 4-12
    • Bastard, J.-P.1    Maachi, M.2    Lagathu, C.3
  • 13
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • G. S. Hotamisligil, "Inflammation and metabolic disorders, " Nature, vol. 444, no. 7121, pp. 860-867, 2006.
    • (2006) Nature , vol.444 , Issue.7121 , pp. 860-867
    • Hotamisligil, G.S.1
  • 14
    • 2342537773 scopus 로고    scopus 로고
    • From blood monocytes to adipose tissue-resident macrophages. Induction of diapedesis by human mature adipocytes
    • C. A. Curat, A. Miranville, C. Sengenes et al. , "From blood monocytes to adipose tissue-resident macrophages. Induction of diapedesis by human mature adipocytes, " Diabetes, vol. 53, no. 5, pp. 1285-1292, 2004.
    • (2004) Diabetes , vol.53 , Issue.5 , pp. 1285-1292
    • Curat, C.A.1    Miranville, A.2    Sengenes, C.3
  • 15
    • 33845864967 scopus 로고    scopus 로고
    • Adipocytes as regulators of energy balance and glucose homeostasis
    • E. D. Rosen and B. M. Spiegelman, "Adipocytes as regulators of energy balance and glucose homeostasis, " Nature, vol. 444, no. 7121, pp. 847-853, 2006.
    • (2006) Nature , vol.444 , Issue.7121 , pp. 847-853
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 16
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-α: Direct role in obesity-linked insulin resistance
    • G. S. Hotamisligil, N. S. Shargill, and B. M. Spiegelman, "Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance, " Science, vol. 259, no. 5091, pp. 87-91, 1993.
    • (1993) Science , vol.259 , Issue.5091 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 18
    • 33748750917 scopus 로고    scopus 로고
    • Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance
    • N. Kamei, K. Tobe, R. Suzuki et al. , "Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance, " The Journal of Biological Chemistry, vol. 281, no. 36, pp. 26602-26614, 2006.
    • (2006) The Journal of Biological Chemistry , vol.281 , Issue.36 , pp. 26602-26614
    • Kamei, N.1    Tobe, K.2    Suzuki, R.3
  • 19
    • 33745216724 scopus 로고    scopus 로고
    • MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
    • H. Kanda, S. Tateya, Y. Tamori et al. , "MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity, "The Journal of Clinical Investigation, vol. 116, no. 6, pp. 1494-1505, 2006.
    • (2006) The Journal of Clinical Investigation , vol.116 , Issue.6 , pp. 1494-1505
    • Kanda, H.1    Tateya, S.2    Tamori, Y.3
  • 20
    • 0034655590 scopus 로고    scopus 로고
    • Leptinspecific patterns of gene expression in white adipose tissue
    • A. Soukas, P. Cohen, N. D. Socci, and J. M. Friedman, "Leptinspecific patterns of gene expression in white adipose tissue, " Genes and Development, vol. 14, no. 8, pp. 963-980, 2000.
    • (2000) Genes and Development , vol.14 , Issue.8 , pp. 963-980
    • Soukas, A.1    Cohen, P.2    Socci, N.D.3    Friedman, J.M.4
  • 22
    • 23644450775 scopus 로고    scopus 로고
    • Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue ofmorbidly obese subjects after surgery-induced weight loss
    • R. Cancello, C. Henegar, N. Viguerie et al. , "Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue ofmorbidly obese subjects after surgery-induced weight loss, " Diabetes, vol. 54, no. 8, pp. 2277-2286, 2005.
    • (2005) Diabetes , vol.54 , Issue.8 , pp. 2277-2286
    • Cancello, R.1    Henegar, C.2    Viguerie, N.3
  • 23
    • 34548639473 scopus 로고    scopus 로고
    • Obesity-induced inflammation: A metabolic dialogue in the language of inflammation
    • A. W. Ferrante Jr. , "Obesity-induced inflammation: a metabolic dialogue in the language of inflammation, " Journal of Internal Medicine, vol. 262, no. 4, pp. 408-414, 2007.
    • (2007) Journal of Internal Medicine , vol.262 , Issue.4 , pp. 408-414
    • Ferrante, A.W.1
  • 24
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • C. N. Lumeng, J. L. Bodzin, and A. R. Saltiel, "Obesity induces a phenotypic switch in adipose tissue macrophage polarization, " The Journal of Clinical Investigation, vol. 117, no. 1, pp. 175-184, 2007.
    • (2007) The Journal of Clinical Investigation , vol.117 , Issue.1 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 25
    • 27444437321 scopus 로고    scopus 로고
    • Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
    • S. Cinti, G. Mitchell, G. Barbatelli et al. , "Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans, " Journal of Lipid Research, vol. 46, no. 11, pp. 2347-2355, 2005.
    • (2005) Journal of Lipid Research , vol.46 , Issue.11 , pp. 2347-2355
    • Cinti, S.1    Mitchell, G.2    Barbatelli, G.3
  • 27
    • 84871053603 scopus 로고    scopus 로고
    • Role of extracellular matrix remodelling in adipose tissue pathophysiology: Relevance in the development of obesity
    • V. Catalan, J. Gomez-Ambrosi, A. Rodriguez, and G. Fruhbeck, "Role of extracellular matrix remodelling in adipose tissue pathophysiology: relevance in the development of obesity, " Histology and Histopathology, vol. 27, no. 12, pp. 1515-1528, 2012.
    • (2012) Histology and Histopathology , vol.27 , Issue.12 , pp. 1515-1528
    • Catalan, V.1    Gomez-Ambrosi, J.2    Rodriguez, A.3    Fruhbeck, G.4
  • 28
    • 84872290190 scopus 로고    scopus 로고
    • Hypoxia and adipose tissue function and dysfunction in obesity
    • P. Trayhurn, "Hypoxia and adipose tissue function and dysfunction in obesity, " Physiological Reviews, vol. 93, no. 1, pp. 1-21, 2013.
    • (2013) Physiological Reviews , vol.93 , Issue.1 , pp. 1-21
    • Trayhurn, P.1
  • 29
    • 54349124582 scopus 로고    scopus 로고
    • Hypoxia and the endocrine and signalling role of white adipose tissue
    • P. Trayhurn, B. Wang, and I. S. Wood, "Hypoxia and the endocrine and signalling role of white adipose tissue, " Archives of Physiology and Biochemistry, vol. 114, no. 4, pp. 267-276, 2008.
    • (2008) Archives of Physiology and Biochemistry , vol.114 , Issue.4 , pp. 267-276
    • Trayhurn, P.1    Wang, B.2    Wood, I.S.3
  • 30
    • 62849107819 scopus 로고    scopus 로고
    • Metabolic dysregulation and adipose tissue fibrosis: Role of collagen VI
    • T. Khan, E. S. Muise, P. Iyengar et al. , "Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI, " Molecular and Cellular Biology, vol. 29, no. 6, pp. 1575-1591, 2009.
    • (2009) Molecular and Cellular Biology , vol.29 , Issue.6 , pp. 1575-1591
    • Khan, T.1    Muise, E.S.2    Iyengar, P.3
  • 31
    • 0035091701 scopus 로고    scopus 로고
    • Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor γ activation has coordinate effects on gene expression in multiple insulin-sensitive tissues
    • J. M. Way, W. W. Harrington, K. K. Brown et al. , "Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor γ activation has coordinate effects on gene expression in multiple insulin-sensitive tissues, " Endocrinology, vol. 142, no. 3, pp. 1269-1277, 2001.
    • (2001) Endocrinology , vol.142 , Issue.3 , pp. 1269-1277
    • Way, J.M.1    Harrington, W.W.2    Brown, K.K.3
  • 32
    • 84859416933 scopus 로고    scopus 로고
    • Regulatory T cells: Mechanisms of differentiation and function
    • S. Z. Josefowicz, L.-F. Lu, and A. Y. Rudensky, "Regulatory T cells: mechanisms of differentiation and function, " Annual Review of Immunology, vol. 30, pp. 531-564, 2012.
    • (2012) Annual Review of Immunology , vol.30 , pp. 531-564
    • Josefowicz, S.Z.1    Lu, L.-F.2    Rudensky, A.Y.3
  • 33
    • 68349148211 scopus 로고    scopus 로고
    • Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affectmetabolic parameters
    • M. Feuerer, L. Herrero, D. Cipolletta et al. , "Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affectmetabolic parameters, " Nature Medicine, vol. 15, no. 8, pp. 930-939, 2009.
    • (2009) Nature Medicine , vol.15 , Issue.8 , pp. 930-939
    • Feuerer, M.1    Herrero, L.2    Cipolletta, D.3
  • 34
    • 0028968879 scopus 로고
    • The expression of tumor necrosis factor in human adipose tissue: Regulation by obesity, weight loss, and relationship to lipoprotein lipase
    • P. A. Kern, M. Saghizadeh, J. M. Ong, R. J. Bosch, R. Deem, and R. B. Simsolo, "The expression of tumor necrosis factor in human adipose tissue: regulation by obesity, weight loss, and relationship to lipoprotein lipase, " The Journal of Clinical Investigation, vol. 95, no. 5, pp. 2111-2119, 1995.
    • (1995) The Journal of Clinical Investigation , vol.95 , Issue.5 , pp. 2111-2119
    • Kern, P.A.1    Saghizadeh, M.2    Ong, J.M.3    Bosch, R.J.4    Deem, R.5    Simsolo, R.B.6
  • 35
    • 74549167737 scopus 로고    scopus 로고
    • Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression
    • E. J. Park, J. H. Lee, G.-Y. Yu et al. , "Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression, " Cell, vol. 140, no. 2, pp. 197-208, 2010.
    • (2010) Cell , vol.140 , Issue.2 , pp. 197-208
    • Park, E.J.1    Lee, J.H.2    Yu, G.-Y.3
  • 36
    • 0036266125 scopus 로고    scopus 로고
    • Altered tumor necrosis factor-κ(TNF-α) processing in adipocytes and increased expression of transmembrane TNF-κin obesity
    • H. Xu, K. T. Uysal, J. D. Becherer, P. Arner, and G. S. Hotamisligil, "Altered tumor necrosis factor-κ(TNF-α) processing in adipocytes and increased expression of transmembrane TNF-κin obesity, " Diabetes, vol. 51, no. 6, pp. 1876-1883, 2002.
    • (2002) Diabetes , vol.51 , Issue.6 , pp. 1876-1883
    • Xu, H.1    Uysal, K.T.2    Becherer, J.D.3    Arner, P.4    Hotamisligil, G.S.5
  • 37
    • 0030756346 scopus 로고    scopus 로고
    • Protection from obesity-induced insulin resistance in mice lacking TNF-κfunction
    • K. T. Uysal, S. M. Wiesbrock, M. W. Marino, and G. S. Hotamisligil, "Protection from obesity-induced insulin resistance in mice lacking TNF-κfunction, " Nature, vol. 389, no. 6651, pp. 610-614, 1997.
    • (1997) Nature , vol.389 , Issue.6651 , pp. 610-614
    • Uysal, K.T.1    Wiesbrock, S.M.2    Marino, M.W.3    Hotamisligil, G.S.4
  • 38
    • 0032749917 scopus 로고    scopus 로고
    • Elevated serum TNF-κlevel as a link between endothelial dysfunctioNandinsulin resistance in normotensive obese patients
    • G. Winkler, P. Lakatos, F. Salamon et al. , "Elevated serum TNF-κlevel as a link between endothelial dysfunctioNandinsulin resistance in normotensive obese patients, " Diabetic Medicine, vol. 16, no. 3, pp. 207-211, 1999.
    • (1999) Diabetic Medicine , vol.16 , Issue.3 , pp. 207-211
    • Winkler, G.1    Lakatos, P.2    Salamon, F.3
  • 40
    • 0029906375 scopus 로고    scopus 로고
    • Effects of an engineered human anti-TNF-κantibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM
    • F. Ofei, S. Hurel, J. Newkirk, M. Sopwith, and R. Taylor, "Effects of an engineered human anti-TNF-κantibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM, " Diabetes, vol. 45, no. 3, pp. 881-885, 1996.
    • (1996) Diabetes , vol.45 , Issue.3 , pp. 881-885
    • Ofei, F.1    Hurel, S.2    Newkirk, J.3    Sopwith, M.4    Taylor, R.5
  • 41
    • 0034454915 scopus 로고    scopus 로고
    • No increased insulin sensitivity after a single intravenous administration of a recombinant human tumor necrosis factor receptor: Fc fusion protein in obese insulin-resistant patients
    • N. Paquot, M. J. Castillo, P. J. Lefebvre, and A. J. Scheen, "No increased insulin sensitivity after a single intravenous administration of a recombinant human tumor necrosis factor receptor: Fc fusion protein in obese insulin-resistant patients, " Journal of Clinical Endocrinology and Metabolism, vol. 85, no. 3, pp. 1316-1319, 2000.
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , Issue.3 , pp. 1316-1319
    • Paquot, N.1    Castillo, M.J.2    Lefebvre, P.J.3    Scheen, A.J.4
  • 42
    • 33748992313 scopus 로고    scopus 로고
    • Adipocytokines:mediators linking adipose tissue, inflammatioNandimmunity
    • H. Tilg and A. R. Moschen, "Adipocytokines:mediators linking adipose tissue, inflammatioNandimmunity, " Nature Reviews Immunology, vol. 6, no. 10, pp. 772-783, 2006.
    • (2006) Nature Reviews Immunology , vol.6 , Issue.10 , pp. 772-783
    • Tilg, H.1    Moschen, A.R.2
  • 43
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
    • K. L. Donnelly, C. I. Smith, S. J. Schwarzenberg, J. Jessurun, M. D. Boldt, and E. J. Parks, "Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease, "The Journal of Clinical Investigation, vol. 115, no. 5, pp. 1343-1351, 2005.
    • (2005) The Journal of Clinical Investigation , vol.115 , Issue.5 , pp. 1343-1351
    • Donnelly, K.L.1    Smith, C.I.2    Schwarzenberg, S.J.3    Jessurun, J.4    Boldt, M.D.5    Parks, E.J.6
  • 44
    • 60549108418 scopus 로고    scopus 로고
    • Cellular and molecular effects of n-3 polyunsaturated fatty acids on adipose tissue biology and metabolism
    • P. Flachs, M. Rossmeisl, M. Bryhn, and J. Kopecky, "Cellular and molecular effects of n-3 polyunsaturated fatty acids on adipose tissue biology and metabolism, " Clinical Science, vol. 116, no. 1, pp. 1-16, 2009.
    • (2009) Clinical Science , vol.116 , Issue.1 , pp. 1-16
    • Flachs, P.1    Rossmeisl, M.2    Bryhn, M.3    Kopecky, J.4
  • 45
    • 78751534190 scopus 로고    scopus 로고
    • Downregulation of adipose tissue fatty acid trafficking in obesity: A driver for ectopic fat deposition?
    • S. E. McQuaid, L. Hodson, M. J. Neville et al. , "Downregulation of adipose tissue fatty acid trafficking in obesity: a driver for ectopic fat deposition?" Diabetes, vol. 60, no. 1, pp. 47-55, 2011.
    • (2011) Diabetes , vol.60 , Issue.1 , pp. 47-55
    • McQuaid, S.E.1    Hodson, L.2    Neville, M.J.3
  • 46
    • 83455216207 scopus 로고    scopus 로고
    • Ectopic fat depots and cardiovascular disease
    • K. A. Britton and C. S. Fox, "Ectopic fat depots and cardiovascular disease, " Circulation, vol. 124, no. 24, pp. e837-e841, 2011.
    • (2011) Circulation , vol.124 , Issue.24 , pp. e837-e841
    • Britton, K.A.1    Fox, C.S.2
  • 47
    • 0030594830 scopus 로고    scopus 로고
    • Decreased cerebrospinal-fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance
    • J. F. Caro, J. W. Kolaczynski, M. R. Nyce et al. , "Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance, " The Lancet, vol. 348, no. 9021, pp. 159-161, 1996.
    • (1996) The Lancet , vol.348 , Issue.9021 , pp. 159-161
    • Caro, J.F.1    Kolaczynski, J.W.2    Nyce, M.R.3
  • 48
    • 33748314535 scopus 로고    scopus 로고
    • Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity
    • R. Cancello, J. Tordjman, C. Poitou et al. , "Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity, " Diabetes, vol. 55, no. 6, pp. 1554-1561, 2006.
    • (2006) Diabetes , vol.55 , Issue.6 , pp. 1554-1561
    • Cancello, R.1    Tordjman, J.2    Poitou, C.3
  • 49
    • 52749092267 scopus 로고    scopus 로고
    • Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals
    • D. Patsouris, P.-P. Li, D. Thapar, J. Chapman, J. M. Olefsky, and J. G. Neels, "Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals, " Cell Metabolism, vol. 8, no. 4, pp. 301-309, 2008.
    • (2008) Cell Metabolism , vol.8 , Issue.4 , pp. 301-309
    • Patsouris, D.1    Li, P.-P.2    Thapar, D.3    Chapman, J.4    Olefsky, J.M.5    Neels, J.G.6
  • 50
    • 70350560546 scopus 로고    scopus 로고
    • Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice
    • S. Fujisaka, I. Usui, A. Bukhari et al. , "Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice, " Diabetes, vol. 58, no. 11, pp. 2574-2582, 2009.
    • (2009) Diabetes , vol.58 , Issue.11 , pp. 2574-2582
    • Fujisaka, S.1    Usui, I.2    Bukhari, A.3
  • 51
    • 73649107296 scopus 로고    scopus 로고
    • Lipogenic enzyme activities and glucose uptake in fat tissue of dyslipemic, insulin-resistant rats: Effects of fish oil
    • A. S. Rossi, Y. B. Lombardo, and A. G. Chicco, "Lipogenic enzyme activities and glucose uptake in fat tissue of dyslipemic, insulin-resistant rats: effects of fish oil, " Nutrition, vol. 26, no. 2, pp. 209-217, 2010.
    • (2010) Nutrition , vol.26 , Issue.2 , pp. 209-217
    • Rossi, A.S.1    Lombardo, Y.B.2    Chicco, A.G.3
  • 52
    • 78651249542 scopus 로고    scopus 로고
    • The role of adipose tissue in mediating the beneficial effects of dietary fish oil
    • M. J. Puglisi, A. H. Hasty, and V. Saraswathi, "The role of adipose tissue in mediating the beneficial effects of dietary fish oil, " The Journal of Nutritional Biochemistry, vol. 22, no. 2, pp. 101-108, 2011.
    • (2011) The Journal of Nutritional Biochemistry , vol.22 , Issue.2 , pp. 101-108
    • Puglisi, M.J.1    Hasty, A.H.2    Saraswathi, V.3
  • 53
    • 84873443547 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids and inflammatory processes: Nutrition or pharmacology?
    • P. C. Calder, "Omega-3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology?" British Journal of Clinical Pharmacology, vol. 75, no. 3, pp. 645-662, 2013.
    • (2013) British Journal of Clinical Pharmacology , vol.75 , Issue.3 , pp. 645-662
    • Calder, P.C.1
  • 54
    • 0037137299 scopus 로고    scopus 로고
    • Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease
    • P. M. Kris-Etherton, W. S. Harris, and L. J. Appel, "Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease, " Circulation, vol. 106, no. 21, pp. 2747-2757, 2002.
    • (2002) Circulation , vol.106 , Issue.21 , pp. 2747-2757
    • Kris-Etherton, P.M.1    Harris, W.S.2    Appel, L.J.3
  • 55
    • 4444360248 scopus 로고    scopus 로고
    • N-3 long chain polyunsaturated fatty acids: A nutritional tool to prevent insulin resistance associated to type 2 diabetes and obesity?
    • J. Delarue, C. LeFoll, C. Corporeau, and D. Lucas, "n-3 long chain polyunsaturated fatty acids: a nutritional tool to prevent insulin resistance associated to type 2 diabetes and obesity?" ReproductionNutritionDevelopment, vol. 44, no. 3, pp. 289-299, 2004.
    • (2004) Reproduction Nutrition Development , vol.44 , Issue.3 , pp. 289-299
    • Delarue, J.1    LeFoll, C.2    Corporeau, C.3    Lucas, D.4
  • 56
    • 0027215407 scopus 로고
    • Fish oil n-3 fatty acids selectively limit the hypertrophy of abdominal fat depots in growing rats fed high-fat diets
    • F. Belzung, T. Raclot, and R. Groscolas, "Fish oil n-3 fatty acids selectively limit the hypertrophy of abdominal fat depots in growing rats fed high-fat diets, " American Journal of Physiology-Regulatory Integrative and Comparative Physiology, vol. 264, no. 6, pp. R1111-R1118, 1993.
    • (1993) American Journal of Physiology-Regulatory Integrative and Comparative Physiology , vol.264 , Issue.6 , pp. R1111-R1118
    • Belzung, F.1    Raclot, T.2    Groscolas, R.3
  • 57
    • 0030700020 scopus 로고    scopus 로고
    • Site-specific regulation of gene expression by n-3 polyunsaturated fatty acids in rat white adipose tissues
    • T. Raclot, R. Groscolas, D. Langin, and P. Ferre, "Site-specific regulation of gene expression by n-3 polyunsaturated fatty acids in rat white adipose tissues, " Journal of Lipid Research, vol. 38, no. 10, pp. 1963-1972, 1997.
    • (1997) Journal of Lipid Research , vol.38 , Issue.10 , pp. 1963-1972
    • Raclot, T.1    Groscolas, R.2    Langin, D.3    Ferre, P.4
  • 58
    • 12544260664 scopus 로고    scopus 로고
    • Omega-3 PUFA of marine origin limit diet-induced obesity in mice by reducing cellularity of adipose tissue
    • J. Ruzickova, M. Rossmeisl, T. Prazak et al. , "Omega-3 PUFA of marine origin limit diet-induced obesity in mice by reducing cellularity of adipose tissue, " Lipids, vol. 39, no. 12, pp. 1177-1185, 2004.
    • (2004) Lipids , vol.39 , Issue.12 , pp. 1177-1185
    • Ruzickova, J.1    Rossmeisl, M.2    Prazak, T.3
  • 59
    • 77956165390 scopus 로고    scopus 로고
    • GPR120 is anomega-3 fatty acid receptor mediating potent anti-inflammatory and insulinsensitizing effects
    • D. Y. Oh, S. Talukdar, E. J. Bae et al. , "GPR120 is anomega-3 fatty acid receptor mediating potent anti-inflammatory and insulinsensitizing effects, " Cell, vol. 142, no. 5, pp. 687-698, 2010.
    • (2010) Cell , vol.142 , Issue.5 , pp. 687-698
    • Oh, D.Y.1    Talukdar, S.2    Bae, E.J.3
  • 60
    • 0030762698 scopus 로고    scopus 로고
    • Effect of dietary fish oil on body fat mass and basal fat oxidation in healthy adults
    • C. Couet, J. Delarue, P. Ritz, J.-M. Antoine, and F. Lamisse, "Effect of dietary fish oil on body fat mass and basal fat oxidation in healthy adults, " International Journal of Obesity, vol. 21, no. 8, pp. 637-643, 1997.
    • (1997) International Journal of Obesity , vol.21 , Issue.8 , pp. 637-643
    • Couet, C.1    Delarue, J.2    Ritz, P.3    Antoine, J.-M.4    Lamisse, F.5
  • 61
    • 0032692793 scopus 로고    scopus 로고
    • Dietary fish as a major component of a weight-loss diet: Effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects
    • T. A. Mori, D. Q. Bao, V. Burke, I. B. Puddey, G. F. Watts, and L. J. Beilin, "Dietary fish as a major component of a weight-loss diet: effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects, " The American Journal of Clinical Nutrition, vol. 70, no. 5, pp. 817-825, 1999.
    • (1999) The American Journal of Clinical Nutrition , vol.70 , Issue.5 , pp. 817-825
    • Mori, T.A.1    Bao, D.Q.2    Burke, V.3    Puddey, I.B.4    Watts, G.F.5    Beilin, L.J.6
  • 62
    • 84950170991 scopus 로고    scopus 로고
    • Long-chain omega-3 polyunsaturated fatty acids may be beneficial for reducing obesity-a review
    • J. D. Buckley and P. R. C. Howe, "Long-chain omega-3 polyunsaturated fatty acids may be beneficial for reducing obesity-a review, " Nutrients, vol. 2, no. 12, pp. 1212-1230, 2010.
    • (2010) Nutrients , vol.2 , Issue.12 , pp. 1212-1230
    • Buckley, J.D.1    Howe, P.R.C.2
  • 63
    • 84855971481 scopus 로고    scopus 로고
    • Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity
    • Article ID e30571
    • D. E. Cintra, E. R. Ropelle, J. C. Moraes et al. , "Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity, " PLoS ONE, vol. 7, no. 1, Article ID e30571, 2012.
    • (2012) PLoS ONE , vol.7 , Issue.1
    • Cintra, D.E.1    Ropelle, E.R.2    Moraes, J.C.3
  • 64
    • 33745222339 scopus 로고    scopus 로고
    • Defining high-fat-diet rat models: Metabolic and molecular effects of different fat types
    • R. Buettner, K. G. Parhofer, M. Woenckhaus et al. , "Defining high-fat-diet rat models: metabolic and molecular effects of different fat types, " Journal of Molecular Endocrinology, vol. 36, no. 3, pp. 485-501, 2006.
    • (2006) Journal of Molecular Endocrinology , vol.36 , Issue.3 , pp. 485-501
    • Buettner, R.1    Parhofer, K.G.2    Woenckhaus, M.3
  • 65
    • 0036776120 scopus 로고    scopus 로고
    • The importance of the ratio of omega-6/omega-3 essential fatty acids
    • A. P. Simopoulos, "The importance of the ratio of omega-6/omega-3 essential fatty acids, " Biomedicine and Pharmacotherapy, vol. 56, no. 8, pp. 365-379, 2002.
    • (2002) Biomedicine and Pharmacotherapy , vol.56 , Issue.8 , pp. 365-379
    • Simopoulos, A.P.1
  • 66
    • 46449123205 scopus 로고    scopus 로고
    • The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases
    • A. P. Simopoulos, "The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases, " Experimental Biology and Medicine, vol. 233, no. 6, pp. 674-688, 2008.
    • (2008) Experimental Biology and Medicine , vol.233 , Issue.6 , pp. 674-688
    • Simopoulos, A.P.1
  • 68
    • 0025755281 scopus 로고
    • Interaction between fish and vegetable oils in relation to rat leucocyte leukotriene production
    • M. J. James, L. G. Cleland , R. A. Gibson, and J. S. Hawkes, "Interaction between fish and vegetable oils in relation to rat leucocyte leukotriene production, " The Journal of Nutrition, vol. 121, no. 5, pp. 631-637, 1991.
    • (1991) The Journal of Nutrition , vol.121 , Issue.5 , pp. 631-637
    • James, M.J.1    Cleland, L.G.2    Gibson, R.A.3    Hawkes, J.S.4
  • 69
    • 60849115290 scopus 로고    scopus 로고
    • N3 and n6 polyunsaturated fatty acids differentially modulate prostagland in e secretion but not markers of lipogenesis in adipocytes
    • article 5
    • P. Wortman, Y. Miyazaki, N. S. Kalupahana et al. , "n3 and n6 polyunsaturated fatty acids differentially modulate prostagland in E secretion but not markers of lipogenesis in adipocytes, " Nutrition and Metabolism, vol. 6, article 5, 2009.
    • (2009) Nutrition and Metabolism , vol.6
    • Wortman, P.1    Miyazaki, Y.2    Kalupahana, N.S.3
  • 70
    • 33746809138 scopus 로고    scopus 로고
    • Distribution, interconversion, and dose response of n-3 fatty acids in humans
    • L. M. Arterburn, E. B. Hall, and H. Oken, "Distribution, interconversion, and dose response of n-3 fatty acids in humans, "The American Journal of Clinical Nutrition, vol. 83, no. 6, pp. S1467-1476S, 2006.
    • (2006) The American Journal of Clinical Nutrition , vol.83 , Issue.6 , pp. S1467-1476S
    • Arterburn, L.M.1    Hall, E.B.2    Oken, H.3
  • 71
    • 61849141189 scopus 로고    scopus 로고
    • α-linolenic acid supplementation and conversion to n-3 longchain polyunsaturated fatty acids in humans
    • J. T. Brenna, N. Salem Jr. , A. J. Sinclair, and S. C. Cunnane, "α-linolenic acid supplementation and conversion to n-3 longchain polyunsaturated fatty acids in humans, " Prostagland ins Leukotrienes and Essential FattyAcids, vol. 80, no. 2-3, pp. 85-91, 2009.
    • (2009) Prostagland Ins Leukotrienes and Essential Fatty Acids , vol.80 , Issue.2-3 , pp. 85-91
    • Brenna, J.T.1    Salem, N.2    Sinclair, A.J.3    Cunnane, S.C.4
  • 73
    • 77951498306 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids regulate lipidmetabolism through several inflammation mediators: Mechanisms and implications for obesity prevention
    • C. C. Tai and S. T. Ding, "N-3 polyunsaturated fatty acids regulate lipidmetabolism through several inflammation mediators: mechanisms and implications for obesity prevention, " The Journal of Nutritional Biochemistry, vol. 21, no. 5, pp. 357-363, 2010.
    • (2010) The Journal of Nutritional Biochemistry , vol.21 , Issue.5 , pp. 357-363
    • Tai, C.C.1    Ding, S.T.2
  • 74
    • 84655174598 scopus 로고    scopus 로고
    • (n-3) Fatty acids alleviate adipose tissue inflammatioNandinsulin resistance: Mechanistic insights
    • N. S. Kalupahana, K. J. Claycombe, and N. Moustaid-Moussa, "(n-3) Fatty acids alleviate adipose tissue inflammatioNandinsulin resistance: mechanistic insights, " Advances in Nutrition, vol. 2, no. 4, pp. 304-316, 2011.
    • (2011) Advances in Nutrition , vol.2 , Issue.4 , pp. 304-316
    • Kalupahana, N.S.1    Claycombe, K.J.2    Moustaid-Moussa, N.3
  • 75
    • 0033957165 scopus 로고    scopus 로고
    • Dietary polyunsaturated fatty acids and inflammatory mediator production
    • M. J. James, R. A. Gibson, and L. G. Cleland , "Dietary polyunsaturated fatty acids and inflammatory mediator production, " The American Journal of ClinicalNutrition, vol. 71, no. 1, supplement, pp. 343S-348S, 2000.
    • (2000) The American Journal of ClinicalNutrition , vol.71 , Issue.1 , pp. 343S-348S
    • James, M.J.1    Gibson, R.A.2    Cleland, L.G.3
  • 76
    • 0021861083 scopus 로고
    • Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophiland monocyte leukotriene generation and neutrophil function
    • T. H. Lee, R. L. Hoover, J. D. Williams et al. , "Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophiland monocyte leukotriene generation and neutrophil function, "The New England Journal ofMedicine, vol. 312, no. 19, pp. 1217-1224, 1985.
    • (1985) The New England Journal of Medicine , vol.312 , Issue.19 , pp. 1217-1224
    • Lee, T.H.1    Hoover, R.L.2    Williams, J.D.3
  • 77
    • 0023472024 scopus 로고
    • Modulation of prostagland in synthesis in mouse peritoneal macrophages by enrichment of lipids with either eicosapentaenoic or docosahexaenoic acids in vitro
    • B. R. Lokesh and J. E. Kinsella, "Modulation of prostagland in synthesis in mouse peritoneal macrophages by enrichment of lipids with either eicosapentaenoic or docosahexaenoic acids in vitro, " Immunobiology, vol. 175, no. 5, pp. 406-419, 1987.
    • (1987) Immunobiology , vol.175 , Issue.5 , pp. 406-419
    • Lokesh, B.R.1    Kinsella, J.E.2
  • 78
    • 33947500462 scopus 로고    scopus 로고
    • Resolvins and protectins in the termination program of acute inflammation
    • A. Arieland C. N. Serhan, "Resolvins and protectins in the termination program of acute inflammation, " Trends in Immunology, vol. 28, no. 4, pp. 176-183, 2007.
    • (2007) Trends in Immunology , vol.28 , Issue.4 , pp. 176-183
    • Ariel, A.1    Serhan, C.N.2
  • 79
    • 77953448663 scopus 로고    scopus 로고
    • Resolution of adipose tissue inflammation
    • A. Gonzalez-Periz and J. Claria, "Resolution of adipose tissue inflammation, " TheScientificWorldJournal, vol. 10, pp. 832-856, 2010.
    • The ScientificWorld Journal , vol.10 , Issue.2010 , pp. 832-856
    • Gonzalez-Periz, A.1    Claria, J.2
  • 80
  • 81
    • 34250357688 scopus 로고    scopus 로고
    • Resolvin E1 and protectin D1 activate inflammation-resolution programmes
    • J. M. Schwab, N. Chiang, M. Arita, and C. N. Serhan, "Resolvin E1 and protectin D1 activate inflammation-resolution programmes, " Nature, vol. 447, no. 7146, pp. 869-874, 2007.
    • (2007) Nature , vol.447 , Issue.7146 , pp. 869-874
    • Schwab, J.M.1    Chiang, N.2    Arita, M.3    Serhan, C.N.4
  • 82
    • 81455131791 scopus 로고    scopus 로고
    • Resolvin D1 and its precursor docosahexaenoic acid promote resolution of adipose tissue inflammation by eliciting macrophage polarization toward an M2-like phenotype
    • E. Titos, B. Rius, A. Gonzalez-Periz et al. , "Resolvin D1 and its precursor docosahexaenoic acid promote resolution of adipose tissue inflammation by eliciting macrophage polarization toward an M2-like phenotype, "The Journal of Immunology, vol. 187, no. 10, pp. 5408-5418, 2011.
    • (2011) The Journal of Immunology , vol.187 , Issue.10 , pp. 5408-5418
    • Titos, E.1    Rius, B.2    Gonzalez-Periz, A.3
  • 83
    • 0030038986 scopus 로고    scopus 로고
    • The effect on human tumor necrosis factor κ and interleukin 1β production of diets enriched in n-3 fatty acids from vegetable oil or fish oil
    • G. E. Caughey, E. Mantzioris, R. A. Gibson, L. G. Cleland , and M. J. James, "The effect on human tumor necrosis factor κ and interleukin 1β production of diets enriched in n-3 fatty acids from vegetable oil or fish oil, " The American Journal of Clinical Nutrition, vol. 63, no. 1, pp. 116-122, 1996.
    • (1996) The American Journal of Clinical Nutrition , vol.63 , Issue.1 , pp. 116-122
    • Caughey, G.E.1    Mantzioris, E.2    Gibson, R.A.3    Cleland, L.G.4    James, M.J.5
  • 84
    • 0025782730 scopus 로고
    • Oral (n-3) fatty acid supplementation suppresses cytokine production and lymphocyte proliferation: Comparison between young and older women
    • S. N. Meydani, S. Endres, M. M. Woods et al. , "Oral (n-3) fatty acid supplementation suppresses cytokine production and lymphocyte proliferation: comparison between young and older women, " Journal of Nutrition, vol. 121, no. 4, pp. 547-555, 1991.
    • (1991) Journal of Nutrition , vol.121 , Issue.4 , pp. 547-555
    • Meydani, S.N.1    Endres, S.2    Woods, M.M.3
  • 85
    • 0024489402 scopus 로고
    • The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells
    • S. Endres, R. Ghorbani, V. E. Kelley et al. , "The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells, " The New England Journal of Medicine, vol. 320, no. 5, pp. 265-271, 1989.
    • (1989) The New England Journal of Medicine , vol.320 , Issue.5 , pp. 265-271
    • Endres, S.1    Ghorbani, R.2    Kelley, V.E.3
  • 87
    • 1042276587 scopus 로고    scopus 로고
    • Eicosapentaenoic acid prevents LPS-induced TNF-κexpression by preventing NF-κB activation
    • Y. Zhao, S. Joshi-Barve, S. Barve, and L. H. Chen, "Eicosapentaenoic acid prevents LPS-induced TNF-κexpression by preventing NF-κB activation, " Journal of the American College of Nutrition, vol. 23, no. 1, pp. 71-78, 2004.
    • (2004) Journal of the American College of Nutrition , vol.23 , Issue.1 , pp. 71-78
    • Zhao, Y.1    Joshi-Barve, S.2    Barve, S.3    Chen, L.H.4
  • 88
  • 89
    • 34548354722 scopus 로고    scopus 로고
    • Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production
    • M. Zeyda, D. Farmer, J. Todoric et al. , "Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production, " International Journal of Obesity, vol. 31, no. 9, pp. 1420-1428, 2007.
    • (2007) International Journal of Obesity , vol.31 , Issue.9 , pp. 1420-1428
    • Zeyda, M.1    Farmer, D.2    Todoric, J.3
  • 90
    • 33746772121 scopus 로고    scopus 로고
    • Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids
    • J. Todoric, M. Loffler, J. Huber et al. , "Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids, " Diabetologia, vol. 49, no. 9, pp. 2109-2119, 2006.
    • (2006) Diabetologia , vol.49 , Issue.9 , pp. 2109-2119
    • Todoric, J.1    Loffler, M.2    Huber, J.3
  • 91
    • 84894058348 scopus 로고    scopus 로고
    • GPR120 on Kupffer cells mediates hepatoprotective effects of ω3-fatty acids
    • D. A. Raptis, P. Limani, J. H. Jang et al. , "GPR120 on Kupffer cells mediates hepatoprotective effects of ω3-fatty acids, " Journal of Hepatology, vol. 60, no. 3, pp. 625-632, 2014.
    • (2014) Journal of Hepatology , vol.60 , Issue.3 , pp. 625-632
    • Raptis, D.A.1    Limani, P.2    Jang, J.H.3
  • 92
    • 33845303165 scopus 로고    scopus 로고
    • Docosahexaenoic acid inhibits adipocyte differentiatioNandinduces apoptosis in 3T3-L1 preadipocytes
    • H.-K. Kim, M. Della-Fera, J. Lin, and C. A. Baile, "Docosahexaenoic acid inhibits adipocyte differentiatioNandinduces apoptosis in 3T3-L1 preadipocytes, " The Journal of Nutrition, vol. 136, no. 12, pp. 2965-2969, 2006.
    • (2006) The Journal of Nutrition , vol.136 , Issue.12 , pp. 2965-2969
    • Kim, H.-K.1    Della-Fera, M.2    Lin, J.3    Baile, C.A.4
  • 93
    • 27744482030 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids of marine origin upregulatemitochondrial biogenesis and induce β-oxidation in white fat
    • P. Flachs, O. Horakova, P. Brauner et al. , "Polyunsaturated fatty acids of marine origin upregulatemitochondrial biogenesis and induce β-oxidation in white fat, " Diabetologia, vol. 48, no. 11, pp. 2365-2375, 2005.
    • (2005) Diabetologia , vol.48 , Issue.11 , pp. 2365-2375
    • Flachs, P.1    Horakova, O.2    Brauner, P.3
  • 94
    • 84876463765 scopus 로고    scopus 로고
    • Anti-obesity effect of n-3 polyunsaturated fatty acids in mice fed high-fat diet is independent of cold-induced thermogenesis
    • P. Janovska, P. Flachs, L. Kazdova, and J. Kopecky, "Anti-obesity effect of n-3 polyunsaturated fatty acids in mice fed high-fat diet is independent of cold-induced thermogenesis, " Physiological Research, vol. 62, no. 2, pp. 153-161, 2013.
    • (2013) Physiological Research , vol.62 , Issue.2 , pp. 153-161
    • Janovska, P.1    Flachs, P.2    Kazdova, L.3    Kopecky, J.4
  • 95
    • 34249812073 scopus 로고    scopus 로고
    • Prevention of high-fat diet-induced adipose tissue remodeling in obese diabetic mice by n-3 polyunsaturated fatty acids
    • J. Huber, M. Loffler, M. Bilban et al. , "Prevention of high-fat diet-induced adipose tissue remodeling in obese diabetic mice by n-3 polyunsaturated fatty acids, " International Journal of Obesity, vol. 31, no. 6, pp. 1004-1013, 2007.
    • (2007) International Journal of Obesity , vol.31 , Issue.6 , pp. 1004-1013
    • Huber, J.1    Loffler, M.2    Bilban, M.3
  • 96
    • 0032520921 scopus 로고    scopus 로고
    • Troglitazone increases the number of small adipocytes without the change of white adipose tissuemass in obese Zucker rats
    • A. Okuno, H. Tamemoto, K. Tobe et al. , "Troglitazone increases the number of small adipocytes without the change of white adipose tissuemass in obese Zucker rats, "The Journal of Clinical Investigation, vol. 101, no. 6, pp. 1354-1361, 1998.
    • (1998) The Journal of Clinical Investigation , vol.101 , Issue.6 , pp. 1354-1361
    • Okuno, A.1    Tamemoto, H.2    Tobe, K.3
  • 97
    • 78149275191 scopus 로고    scopus 로고
    • Eicosapentaenoic acid prevents and reverses insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation
    • N. S. Kalupahana, K. Claycombe, S. J. Newman et al. , "Eicosapentaenoic acid prevents and reverses insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation, " The Journal of Nutrition, vol. 140, no. 11, pp. 1915-1922, 2010.
    • (2010) The Journal of Nutrition , vol.140 , Issue.11 , pp. 1915-1922
    • Kalupahana, N.S.1    Claycombe, K.2    Newman, S.J.3
  • 99
    • 79956282374 scopus 로고    scopus 로고
    • The regulation of leptin, leptin receptor and pro-opiomelanocortin expression by N-3 PUFAs in diet-induced obese mice is not related to the methylation of their promoters
    • article 31
    • C. Fan, X. Liu, W. Shen, R. J. Deckelbaum, and K. Qi, "The regulation of leptin, leptin receptor and pro-opiomelanocortin expression by N-3 PUFAs in diet-induced obese mice is not related to the methylation of their promoters, " Nutrition and Metabolism, vol. 8, article 31, 2011.
    • Nutrition and Metabolism , vol.8 , pp. 2011
    • Fan, C.1    Liu, X.2    Shen, W.3    Deckelbaum, R.J.4    Qi, K.5
  • 100
    • 31844451413 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids of marine origin induce adiponectin in mice fed a high-fat diet
    • P. Flachs, V. Mohamed-Ali, O. Horakova et al. , "Polyunsaturated fatty acids of marine origin induce adiponectin in mice fed a high-fat diet, " Diabetologia, vol. 49, no. 2, pp. 394-397, 2006.
    • (2006) Diabetologia , vol.49 , Issue.2 , pp. 394-397
    • Flachs, P.1    Mohamed-Ali, V.2    Horakova, O.3
  • 101
    • 67449097764 scopus 로고    scopus 로고
    • Effects of eicosapentaenoic acid ethyl ester on visfatin and apelin in lean and overweight (cafeteria diet-fed) rats
    • N. Perez-Echarri, P. Perez-Matute, B. Marcos-Gomez, J. A. Martinez, and M. J. Moreno-Aliaga, "Effects of eicosapentaenoic acid ethyl ester on visfatin and apelin in lean and overweight (cafeteria diet-fed) rats, " British Journal of Nutrition, vol. 101, no. 7, pp. 1059-1067, 2009.
    • (2009) British Journal of Nutrition , vol.101 , Issue.7 , pp. 1059-1067
    • Perez-Echarri, N.1    Perez-Matute, P.2    Marcos-Gomez, B.3    Martinez, J.A.4    Moreno-Aliaga, M.J.5
  • 102
    • 0242661906 scopus 로고    scopus 로고
    • A fish oil diet does not reverse insulin resistance despite decreased adipose tissue TNF-κprotein concentration inApoE-3∗ Leiden mice
    • M. Muurling, R. P. Mensink, H. Pijl, J. A. Romijn, L. M. Havekes, and P. J. Voshol, "A fish oil diet does not reverse insulin resistance despite decreased adipose tissue TNF-κprotein concentration inApoE-3∗ leiden mice, " Journal ofNutrition, vol. 133, no. 11, pp. 3350-3355, 2003.
    • (2003) Journal OfNutrition , vol.133 , Issue.11 , pp. 3350-3355
    • Muurling, M.1    Mensink, R.P.2    Pijl, H.3    Romijn, J.A.4    Havekes, L.M.5    Voshol, P.J.6
  • 103
    • 53549120196 scopus 로고    scopus 로고
    • Differential inflammatory status in rats susceptible or resistant to diet-induced obesity: Effects of EPA ethyl ester treatment
    • N. Perez-Echarri, P. Perez-Matute, B. Marcos-Gomez et al. , "Differential inflammatory status in rats susceptible or resistant to diet-induced obesity: effects of EPA ethyl ester treatment, " European Journal of Nutrition, vol. 47, no. 7, pp. 380-386, 2008.
    • (2008) European Journal of Nutrition , vol.47 , Issue.7 , pp. 380-386
    • Perez-Echarri, N.1    Perez-Matute, P.2    Marcos-Gomez, B.3
  • 104
    • 9344233301 scopus 로고    scopus 로고
    • Dietary (n-3) polyunsaturated fatty acids improve adipocyte insulin action and glucose metabolism in insulin-resistant rats: Relation to membrane fatty acids
    • J. Luo, S. W. Rizkalla, J. Boillot et al. , "Dietary (n-3) polyunsaturated fatty acids improve adipocyte insulin action and glucose metabolism in insulin-resistant rats: relation to membrane fatty acids, " The Journal of Nutrition, vol. 126, no. 8, pp. 1951-1958, 1996.
    • (1996) The Journal of Nutrition , vol.126 , Issue.8 , pp. 1951-1958
    • Luo, J.1    Rizkalla, S.W.2    Boillot, J.3
  • 105
    • 0031978492 scopus 로고    scopus 로고
    • Dietary (n-3) and (n-6) polyunsaturated fatty acids rapidly modify fatty acid compositioNandinsulin effects in rat adipocytes
    • M. Fickova, P. Hubert, G. Cremel, and C. Leray, "Dietary (n-3) and (n-6) polyunsaturated fatty acids rapidly modify fatty acid compositioNandinsulin effects in rat adipocytes, " The Journal of Nutrition, vol. 128, no. 3, pp. 512-519, 1998.
    • (1998) The Journal of Nutrition , vol.128 , Issue.3 , pp. 512-519
    • Fickova, M.1    Hubert, P.2    Cremel, G.3    Leray, C.4
  • 106
    • 0030721032 scopus 로고    scopus 로고
    • Differential accumulation and release of long-chain n-3 fatty acids from liver, muscle, and adipose tissue triacylglycerols
    • G. R. Herzberg and C. Skinner, "Differential accumulation and release of long-chain n-3 fatty acids from liver, muscle, and adipose tissue triacylglycerols, " Canadian Journal of Physiology and Pharmacology, vol. 75, no. 8, pp. 945-951, 1997.
    • (1997) Canadian Journal of Physiology and Pharmacology , vol.75 , Issue.8 , pp. 945-951
    • Herzberg, G.R.1    Skinner, C.2
  • 107
    • 33749130207 scopus 로고    scopus 로고
    • Additive benefits of long-chain n-3 polyunsaturated fatty acids and weight-loss in the management of cardiovascular disease risk in overweight hyperinsulinaemic women
    • J. D. Krebs, L. M. Browning, N. K. McLean et al. , "Additive benefits of long-chain n-3 polyunsaturated fatty acids and weight-loss in the management of cardiovascular disease risk in overweight hyperinsulinaemic women, " International Journal of Obesity, vol. 30, no. 10, pp. 1535-1544, 2006.
    • (2006) International Journal of Obesity , vol.30 , Issue.10 , pp. 1535-1544
    • Krebs, J.D.1    Browning, L.M.2    McLean, N.K.3
  • 108
    • 34249889960 scopus 로고    scopus 로고
    • Metabolic syndrome: Effects of n-3 PUFAs on a model of dyslipidemia, insulin resistance and adiposity
    • Y. B. Lombardo, G. Hein, and A. Chicco, "Metabolic syndrome: effects of n-3 PUFAs on a model of dyslipidemia, insulin resistance and adiposity, " Lipids, vol. 42, no. 5, pp. 427-437, 2007.
    • (2007) Lipids , vol.42 , Issue.5 , pp. 427-437
    • Lombardo, Y.B.1    Hein, G.2    Chicco, A.3
  • 109
    • 0023359748 scopus 로고
    • Lipoprotein lipases, lipoproteins and tissue lipids in rats fed fish oil or coconut oil
    • A. Haug and A. T. Hostmark, "Lipoprotein lipases, lipoproteins and tissue lipids in rats fed fish oil or coconut oil, " Journal of Nutrition, vol. 117, no. 6, pp. 1011-1017, 1987.
    • (1987) Journal of Nutrition , vol.117 , Issue.6 , pp. 1011-1017
    • Haug, A.1    Hostmark, A.T.2
  • 110
    • 0036851817 scopus 로고    scopus 로고
    • Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
    • T. Yamauchi, J. Kamon, Y. Minokoshi et al. , "Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase, " Nature Medicine, vol. 8, no. 11, pp. 1288-1295, 2002.
    • (2002) Nature Medicine , vol.8 , Issue.11 , pp. 1288-1295
    • Yamauchi, T.1    Kamon, J.2    Minokoshi, Y.3
  • 111
    • 33846456211 scopus 로고    scopus 로고
    • Effect of PPAR-γ agonist on adiponectin levels in the metabolic syndrome: Lessons fromthe high fructose fed ratmodel
    • Y. Sharabi, M. Oron-Herman, Y. Kamari et al. , "Effect of PPAR-γ agonist on adiponectin levels in the metabolic syndrome: lessons fromthe high fructose fed ratmodel, " American Journal of Hypertension, vol. 20, no. 2, pp. 206-210, 2007.
    • (2007) American Journal of Hypertension , vol.20 , Issue.2 , pp. 206-210
    • Sharabi, Y.1    Oron-Herman, M.2    Kamari, Y.3
  • 112
    • 77951872309 scopus 로고    scopus 로고
    • Adiponectin and AdipoR1 regulate PGC-1κ and mitochondria by Ca2+ and AMPK/SIRT1
    • M. Iwabu, T. Yamauchi, M. Okada-Iwabu et al. , "Adiponectin and AdipoR1 regulate PGC-1κ and mitochondria by Ca2+ and AMPK/SIRT1, " Nature, vol. 464, no. 7293, pp. 1313-1319, 2010.
    • (2010) Nature , vol.464 , Issue.7293 , pp. 1313-1319
    • Iwabu, M.1    Yamauchi, T.2    Okada-Iwabu, M.3
  • 113
    • 52949096557 scopus 로고    scopus 로고
    • Hypothalamic IKKβ/NF-κB and ER stress link overnutrition to energy imbalance and obesity
    • X. Zhang, G. Zhang, H. Zhang, M. Karin, H. Bai, and D. Cai, "Hypothalamic IKKβ/NF-κB and ER stress link overnutrition to energy imbalance and obesity, " Cell, vol. 135, no. 1, pp. 61-73, 2008.
    • (2008) Cell , vol.135 , Issue.1 , pp. 61-73
    • Zhang, X.1    Zhang, G.2    Zhang, H.3    Karin, M.4    Bai, H.5    Cai, D.6
  • 114
    • 58849149821 scopus 로고    scopus 로고
    • Saturatedfatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: Implications for the pathogenesis of obesity
    • M. Milanski, G. Degasperi, A. Coope et al. , "Saturatedfatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity, "TheJournal of Neuroscience, vol. 29, no. 2, pp. 359-370, 2009.
    • (2009) The Journal of Neuroscience , vol.29 , Issue.2 , pp. 359-370
    • Milanski, M.1    Degasperi, G.2    Coope, A.3
  • 115
    • 33646524699 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and inflammation
    • L. A. Moraes, L. Piqueras, and D. Bishop-Bailey, "Peroxisome proliferator-activated receptors and inflammation, " Pharmacology and Therapeutics, vol. 110, no. 3, pp. 371-385, 2006.
    • (2006) Pharmacology and Therapeutics , vol.110 , Issue.3 , pp. 371-385
    • Moraes, L.A.1    Piqueras, L.2    Bishop-Bailey, D.3
  • 116
    • 79951672427 scopus 로고    scopus 로고
    • EPAinhibits the inhibitor ofκbα(IκBα)/NF-κB/muscle RING finger 1 pathway in C2C12 myotubes in a PPARγ-dependent manner
    • F. Huang, H. Wei, H. Luo, S. Jiang, and J. Peng, "EPAinhibits the inhibitor ofκbα(IκBα)/NF-κB/muscle RING finger 1 pathway in C2C12 myotubes in a PPARγ-dependent manner, " British Journal of Nutrition, vol. 105, no. 3, pp. 348-356, 2011.
    • (2011) British Journal of Nutrition , vol.105 , Issue.3 , pp. 348-356
    • Huang, F.1    Wei, H.2    Luo, H.3    Jiang, S.4    Peng, J.5
  • 117
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
    • M. Ricote, A. C. Li, T. M. Willson, C. J. Kelly, and C. K. Glass, "The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation, " Nature, vol. 391, no. 6662, pp. 79-82, 1998.
    • (1998) Nature , vol.391 , Issue.6662 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 118
    • 82955188750 scopus 로고    scopus 로고
    • N-3 PUFA supplementation triggers PPAR-κactivation and PPAR-α/NF-κB interaction: Anti-inflammatory implications in liver ischemiareperfusion injury
    • Article IDe28502
    • J. Zuniga, M. Cancino, F. Medina et al. , "N-3 PUFA supplementation triggers PPAR-κactivation and PPAR-α/NF-κB interaction: anti-inflammatory implications in liver ischemiareperfusion injury, " PLoS ONE, vol. 6, no. 12, Article IDe28502, 2011.
    • PLoS ONE , vol.6 , Issue.12 , pp. 2011
    • Zuniga, J.1    Cancino, M.2    Medina, F.3
  • 119
    • 77949319549 scopus 로고    scopus 로고
    • N-3 PUFA: Bioavailability and modulation of adipose tissue function
    • J. Kopecky, M. Rossmeisl, P. Flachs et al. , "N-3 PUFA: bioavailability and modulation of adipose tissue function, " Proceedings of the Nutrition Society, vol. 68, no. 4, pp. 361-369, 2009.
    • (2009) Proceedings of the Nutrition Society , vol.68 , Issue.4 , pp. 361-369
    • Kopecky, J.1    Rossmeisl, M.2    Flachs, P.3
  • 120
    • 0032785350 scopus 로고    scopus 로고
    • Eicosapentaenoic acid inhibits prostagland in D2 generation by inhibiting cyclo-oxygenase-2 in cultured human mast cells
    • T. Obata, T. Nagakura, T. Masaki, K. Maekawa, and K. Yamashita, "Eicosapentaenoic acid inhibits prostagland in D2 generation by inhibiting cyclo-oxygenase-2 in cultured human mast cells, " Clinical and Experimental Allergy, vol. 29, no. 8, pp. 1129-1135, 1999.
    • (1999) Clinical and Experimental Allergy , vol.29 , Issue.8 , pp. 1129-1135
    • Obata, T.1    Nagakura, T.2    Masaki, T.3    Maekawa, K.4    Yamashita, K.5
  • 122
    • 0035813215 scopus 로고    scopus 로고
    • Polyunsaturated eicosapentaenoic acid displaces proteins from membrane rafts by altering raft lipid composition
    • T. M. Stulnig, J. Huber, N. Leitinger et al. , "Polyunsaturated eicosapentaenoic acid displaces proteins from membrane rafts by altering raft lipid composition, " Journal of Biological Chemistry, vol. 276, no. 40, pp. 37335-37340, 2001.
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.40 , pp. 37335-37340
    • Stulnig, T.M.1    Huber, J.2    Leitinger, N.3
  • 123
    • 24344438206 scopus 로고    scopus 로고
    • Docosahexaenoic acid changes lipid compositioNandinterleukin-2 receptor signaling in membrane rafts
    • Q. Li, M. Wang, L. Tan et al. , "Docosahexaenoic acid changes lipid compositioNandinterleukin-2 receptor signaling in membrane rafts, " The Journal of Lipid Research, vol. 46, no. 9, pp. 1904-1913, 2005.
    • (2005) The Journal of Lipid Research , vol.46 , Issue.9 , pp. 1904-1913
    • Li, Q.1    Wang, M.2    Tan, L.3
  • 124
    • 84875204850 scopus 로고    scopus 로고
    • Electrophilic nitro-fatty acids inhibit vascular inflammation by disrupting LPS-dependent TLR4 signalling in lipid rafts
    • L. Villacorta, L. Chang, S. R. Salvatore et al. , "Electrophilic nitro-fatty acids inhibit vascular inflammation by disrupting LPS-dependent TLR4 signalling in lipid rafts, " Cardiovascular Research, vol. 98, no. 1, pp. 116-124, 2013.
    • (2013) Cardiovascular Research , vol.98 , Issue.1 , pp. 116-124
    • Villacorta, L.1    Chang, L.2    Salvatore, S.R.3
  • 125
    • 0029661982 scopus 로고    scopus 로고
    • The PPARα-leukotriene B4 pathway to inflammation control
    • P. R. Devchand , H. Keller, J. M. Peters, M. Vazquez, F. J. Gonzalez, and W. Wahli, "The PPARα-leukotriene B4 pathway to inflammation control, " Nature, vol. 384, no. 6604, pp. 39-43, 1996.
    • (1996) Nature , vol.384 , Issue.6604 , pp. 39-43
    • Devchand, P.R.1    Keller, H.2    Peters, J.M.3    Vazquez, M.4    Gonzalez, F.J.5    Wahli, W.6
  • 126
    • 38449085356 scopus 로고    scopus 로고
    • Mechanisms of antiinflammatory and neuroprotective actions of PPAR-gamma agonists
    • R. Kapadia, J.-H. Yi, and R. Vemuganti, "Mechanisms of antiinflammatory and neuroprotective actions of PPAR-gamma agonists, " Frontiers in Bioscience, vol. 13, no. 5, pp. 1813-1826, 2008.
    • (2008) Frontiers in Bioscience , vol.13 , Issue.5 , pp. 1813-1826
    • Kapadia, R.1    Yi, J.-H.2    Vemuganti, R.3
  • 127
    • 0028015713 scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR)γ: Adiposepredominant expressioNandinduction early in adipocyte differentiation
    • A. Chawla, E. J. Schwarz, D. D. Dimaculangan, and M. A. Lazar, "Peroxisome proliferator-activated receptor (PPAR)γ: adiposepredominant expressioNandinduction early in adipocyte differentiation, " Endocrinology, vol. 135, no. 2, pp. 798-800, 1994.
    • (1994) Endocrinology , vol.135 , Issue.2 , pp. 798-800
    • Chawla, A.1    Schwarz, E.J.2    Dimaculangan, D.D.3    Lazar, M.A.4
  • 128
    • 0031898610 scopus 로고    scopus 로고
    • PPAR-γ: Adipogenic regulator and thiazolidinedione receptor
    • B. M. Spiegelman, "PPAR-γ: adipogenic regulator and thiazolidinedione receptor, " Diabetes, vol. 47, no. 4, pp. 507-514, 1998.
    • (1998) Diabetes , vol.47 , Issue.4 , pp. 507-514
    • Spiegelman, B.M.1
  • 129
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
    • P. Tontonoz, E. Hu, and B. M. Spiegelman, "Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor, " Cell, vol. 79, no. 7, pp. 1147-1156, 1994.
    • (1994) Cell , vol.79 , Issue.7 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 130
    • 34247855853 scopus 로고    scopus 로고
    • Adipose tissue distribution and risk of metabolic disease: Does thiazolidinedione-induced adipose tissue redistribution provide a clue to the answer?
    • X. Yang and U. Smith, "Adipose tissue distribution and risk of metabolic disease: does thiazolidinedione-induced adipose tissue redistribution provide a clue to the answer?" Diabetologia, vol. 50, no. 6, pp. 1127-1139, 2007.
    • (2007) Diabetologia , vol.50 , Issue.6 , pp. 1127-1139
    • Yang, X.1    Smith, U.2
  • 131
    • 76349098660 scopus 로고    scopus 로고
    • Adiponectin: An indispensable molecule in rosiglitazone cardioprotection following myocardial infarction
    • L. Tao, Y. Wang, E. Gao et al. , "Adiponectin: an indispensable molecule in rosiglitazone cardioprotection following myocardial infarction, " Circulation Research, vol. 106, no. 2, pp. 409-417, 2010.
    • (2010) Circulation Research , vol.106 , Issue.2 , pp. 409-417
    • Tao, L.1    Wang, Y.2    Gao, E.3
  • 132
    • 79551499779 scopus 로고    scopus 로고
    • Eicosapentaenoic acid and rosiglitazone increase adiponectin in an additive and PPARγ-dependent manner in human adipocytes
    • J. M. Tishinsky, D. W. L. Ma, and L. E. Robinson, "Eicosapentaenoic acid and rosiglitazone increase adiponectin in an additive and PPARγ-dependent manner in human adipocytes, " Obesity, vol. 19, no. 2, pp. 262-268, 2011.
    • (2011) Obesity , vol.19 , Issue.2 , pp. 262-268
    • Tishinsky, J.M.1    Ma, D.W.L.2    Robinson, L.E.3
  • 133
    • 33745305434 scopus 로고    scopus 로고
    • Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptor-γ-dependent mechanism in mice
    • S. Neschen, K. Morino, J. C. Rossbacher et al. , "Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptor-γ-dependent mechanism in mice, " Diabetes, vol. 55, no. 4, pp. 924-928, 2006.
    • (2006) Diabetes , vol.55 , Issue.4 , pp. 924-928
    • Neschen, S.1    Morino, K.2    Rossbacher, J.C.3
  • 134
    • 53049093989 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ activation promotes infiltration of alternatively activated macrophages into adipose tissue
    • R. Stienstra, C. Duval, S. Keshtkar, J. van der Laak, S. Kersten, and M. Muller, "Peroxisome proliferator-activated receptor γ activation promotes infiltration of alternatively activated macrophages into adipose tissue, " The Journal of Biological Chemistry, vol. 283, no. 33, pp. 22620-22627, 2008.
    • (2008) The Journal of Biological Chemistry , vol.283 , Issue.33 , pp. 22620-22627
    • Stienstra, R.1    Duval, C.2    Keshtkar, S.3    Laak Der J.Van4    Kersten, S.5    Muller, M.6
  • 135
    • 34347354309 scopus 로고    scopus 로고
    • Macrophage-specific PPARγ controls alternative activatioNandimproves insulin resistance
    • J. I. Odegaard, R. R. Ricardo-Gonzalez, M. H. Goforth et al. , "Macrophage-specific PPARγ controls alternative activatioNandimproves insulin resistance, " Nature, vol. 447, no. 7148, pp. 1116-1120, 2007.
    • (2007) Nature , vol.447 , Issue.7148 , pp. 1116-1120
    • Odegaard, J.I.1    Ricardo-Gonzalez, R.R.2    Goforth, M.H.3
  • 136
    • 34249907880 scopus 로고    scopus 로고
    • Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
    • A. L. Hevener, J. M. Olefsky, D. Reichart et al. , "Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones, " The Journal of Clinical Investigation, vol. 117, no. 6, pp. 1658-1669, 2007.
    • (2007) The Journal of Clinical Investigation , vol.117 , Issue.6 , pp. 1658-1669
    • Hevener, A.L.1    Olefsky, J.M.2    Reichart, D.3
  • 137
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
    • C. Jiang, A. T. Ting, and B. Seed, "PPAR-γ agonists inhibit production of monocyte inflammatory cytokines, " Nature, vol. 391, no. 6662, pp. 82-86, 1998.
    • (1998) Nature , vol.391 , Issue.6662 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 138
    • 84862986986 scopus 로고    scopus 로고
    • PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells
    • D. Cipolletta, M. Feuerer, A. Li et al. , "PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells, " Nature, vol. 486, no. 7404, pp. 549-553, 2012.
    • (2012) Nature , vol.486 , Issue.7404 , pp. 549-553
    • Cipolletta, D.1    Feuerer, M.2    Li, A.3
  • 139
    • 0030985318 scopus 로고    scopus 로고
    • Fatty acids, eicosanoids, and hypolipidemic agents identified as lig and s of peroxisome proliferator-activated receptors by coactivator-dependent receptor lig and assay
    • G. Krey, O. Braissant, F. L Horset et al. , "Fatty acids, eicosanoids, and hypolipidemic agents identified as lig and s of peroxisome proliferator-activated receptors by coactivator-dependent receptor lig and assay, " Molecular Endocrinology, vol. 11, no. 6, pp. 779-791, 1997.
    • (1997) Molecular Endocrinology , vol.11 , Issue.6 , pp. 779-791
    • Krey, G.1    Braissant, O.2    Horset, F.L.3
  • 140
    • 77955502543 scopus 로고    scopus 로고
    • The role of inflammation and macrophage accumulation in the development of obesity-induced type 2 diabetes mellitus and the possible therapeutic effects of long-chain n-3 PUFA
    • E. Oliver, F. McGillicuddy, C. Phillips, S. Toomey, and H. M. Roche, "The role of inflammation and macrophage accumulation in the development of obesity-induced type 2 diabetes mellitus and the possible therapeutic effects of long-chain n-3 PUFA, " Proceedings of the Nutrition Society, vol. 69, no. 2, pp. 232-243, 2010.
    • (2010) Proceedings of the Nutrition Society , vol.69 , Issue.2 , pp. 232-243
    • Oliver, E.1    McGillicuddy, F.2    Phillips, C.3    Toomey, S.4    Roche, H.M.5
  • 141
    • 78650878363 scopus 로고    scopus 로고
    • NF-κB, inflammation, and metabolic disease
    • R. G. Baker, M. S. Hayden, and S. Ghosh, "NF-κB, inflammation, and metabolic disease, " Cell Metabolism, vol. 13, no. 1, pp. 11-22, 2011.
    • (2011) Cell Metabolism , vol.13 , Issue.1 , pp. 11-22
    • Baker, R.G.1    Hayden, M.S.2    Ghosh, S.3
  • 142
    • 14644427890 scopus 로고    scopus 로고
    • Localand systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
    • D. Cai, M. Yuan, D. F. Frantz et al. , "Localand systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB, " Nature Medicine, vol. 11, no. 2, pp. 183-190, 2005.
    • (2005) Nature Medicine , vol.11 , Issue.2 , pp. 183-190
    • Cai, D.1    Yuan, M.2    Frantz, D.F.3
  • 143
    • 20044387026 scopus 로고    scopus 로고
    • IKK-β links inflammation to obesity-induced insulin resistance
    • M. C. Arkan, A. L. Hevener, F. R. Greten et al. , "IKK-β links inflammation to obesity-induced insulin resistance, " Nature Medicine, vol. 11, no. 2, pp. 191-198, 2005.
    • (2005) Nature Medicine , vol.11 , Issue.2 , pp. 191-198
    • Arkan, M.C.1    Hevener, A.L.2    Greten, F.R.3
  • 144
    • 4043088499 scopus 로고    scopus 로고
    • IKKβ links inflammation and tumorigenesis in a mouse model of colitisassociated cancer
    • F. R. Greten, L. Eckmann, T. F. Greten et al. , "IKKβ links inflammation and tumorigenesis in a mouse model of colitisassociated cancer, " Cell, vol. 118, no. 3, pp. 285-296, 2004.
    • (2004) Cell , vol.118 , Issue.3 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3
  • 145
    • 84883204089 scopus 로고    scopus 로고
    • DHA inhibits protein degradation more efficiently than EPA by regulating the PPARγ /NFκB pathway in C2C12 myotubes
    • Article ID 318981
    • Y. Wang, Q.-W. Lin, P.-P. Zheng, J.-S. Zhang, and F.-R. Huang, "DHA inhibits protein degradation more efficiently than EPA by regulating the PPARγ /NFκB pathway in C2C12 myotubes, " BioMed Research International, vol. 2013, Article ID 318981, 9 pages, 2013.
    • (2013) Bio Med Research International , vol.2013 , pp. 9
    • Wang, Y.1    Lin, Q.-W.2    Zheng, P.-P.3    Zhang, J.-S.4    Huang, F.-R.5
  • 146
    • 0035907302 scopus 로고    scopus 로고
    • Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
    • J. Y. Lee, K. H. Sohn, S. H. Rhee, and D. Hwang, "Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4, " The Journal of Biological Chemistry, vol. 276, no. 20, pp. 16683-16689, 2001.
    • (2001) The Journal of Biological Chemistry , vol.276 , Issue.20 , pp. 16683-16689
    • Lee, J.Y.1    Sohn, K.H.2    Rhee, S.H.3    Hwang, D.4
  • 147
    • 13444263540 scopus 로고    scopus 로고
    • Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120
    • A. Hirasawa, K. Tsumaya, T. Awaji et al. , "Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120, " Nature Medicine, vol. 11, no. 1, pp. 90-94, 2005.
    • (2005) Nature Medicine , vol.11 , Issue.1 , pp. 90-94
    • Hirasawa, A.1    Tsumaya, K.2    Awaji, T.3
  • 148
    • 84858285593 scopus 로고    scopus 로고
    • Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human
    • A. Ichimura, A. Hirasawa, O. Poulain-Godefroy et al. , "Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human, " Nature, vol. 483, no. 7389, pp. 350-354, 2012.
    • (2012) Nature , vol.483 , Issue.7389 , pp. 350-354
    • Ichimura, A.1    Hirasawa, A.2    Poulain-Godefroy, O.3
  • 149
    • 84867398818 scopus 로고    scopus 로고
    • The role of nutrition on epigeneticmodifications and their implications on health
    • J. C. Jimenez-Chillaron, R. Diaz, D. Martinez et al. , "The role of nutrition on epigeneticmodifications and their implications on health, " Biochimie, vol. 94, no. 11, pp. 2242-2263, 2012.
    • (2012) Biochimie , vol.94 , Issue.11 , pp. 2242-2263
    • Jimenez-Chillaron, J.C.1    Diaz, R.2    Martinez, D.3
  • 151
    • 79960990097 scopus 로고    scopus 로고
    • Eicosapentaenoic acid demethylates a single CpG that mediates expression of tumor suppressor CCAAT/enhancer-binding protein δ in U937 leukemia cells
    • V. Ceccarelli, S. Racanicchi, M. P. Martelli et al. , "Eicosapentaenoic acid demethylates a single CpG that mediates expression of tumor suppressor CCAAT/enhancer-binding protein δ in U937 leukemia cells, "The Journal of Biological Chemistry, vol. 286, no. 31, pp. 27092-27102, 2011.
    • (2011) The Journal of Biological Chemistry , vol.286 , Issue.31 , pp. 27092-27102
    • Ceccarelli, V.1    Racanicchi, S.2    Martelli, M.P.3
  • 152
    • 79960226240 scopus 로고    scopus 로고
    • Characterizing the profile of obese patients who are metabolically healthy
    • V. Primeau, L. Coderre, A. D. Karelis et al. , "Characterizing the profile of obese patients who are metabolically healthy, " International Journal of Obesity, vol. 35, no. 7, pp. 971-981, 2011.
    • (2011) International Journal of Obesity , vol.35 , Issue.7 , pp. 971-981
    • Primeau, V.1    Coderre, L.2    Karelis, A.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.