메뉴 건너뛰기




Volumn 14, Issue 8, 2000, Pages 963-980

Leptin-specific patterns of gene expression in white adipose tissue

Author keywords

Adipocyte; Cluster; Leptin; Microarray; Obesity; SREBP

Indexed keywords

LEPTIN; RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN;

EID: 0034655590     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (444)

References (51)
  • 3
    • 0032582685 scopus 로고    scopus 로고
    • Obesity-related overexpression of fatty-acid synthase gene in adipose tissue involves sterol regulatory element-binding protein transcription factors
    • Boizard, M., X. Le Liepvre, P. Lemarchand, F. Foufelle, P. Ferre, and I. Dugail. 1998. Obesity-related overexpression of fatty-acid synthase gene in adipose tissue involves sterol regulatory element-binding protein transcription factors. J. Biol. Chem. 273: 29164-29171.
    • (1998) J. Biol. Chem. , vol.273 , pp. 29164-29171
    • Boizard, M.1    Le Liepvre, X.2    Lemarchand, P.3    Foufelle, F.4    Ferre, P.5    Dugail, I.6
  • 4
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • Brown, M.S. and J.L. Goldstein. 1997. The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89: 331-340.
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 5
    • 0033613147 scopus 로고    scopus 로고
    • A proteolytic pathway that controls the cholesterol content of membranes, cells and blood
    • _. 1999. A proteolytic pathway that controls the cholesterol content of membranes, cells and blood. Proc, Natl. Acad. Sci. 96: 11041-11048.
    • (1999) Proc, Natl. Acad. Sci. , vol.96 , pp. 11041-11048
  • 6
    • 0029048408 scopus 로고
    • Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
    • Campfield, L.A., F.J. Smith, Y. Guisez, R. Devos, and P. Burn. 1995. Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks. Science 269: 546-549.
    • (1995) Science , vol.269 , pp. 546-549
    • Campfield, L.A.1    Smith, F.J.2    Guisez, Y.3    Devos, R.4    Burn, P.5
  • 7
    • 0018139377 scopus 로고
    • Obese and Diabetes: Two mutant genes causing diabetes-obesity syndromes in mice
    • Coleman, D.L. 1978. Obese and Diabetes: Two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 14: 141-148.
    • (1978) Diabetologia , vol.14 , pp. 141-148
    • Coleman, D.L.1
  • 10
    • 0030830662 scopus 로고    scopus 로고
    • Intracerebroventricular leptin increases lumbar and renal sympathetic nerve activity and blood pressure in normal rats
    • Dunbar, J.C., Y. Hu, and H. Lu. 1997. Intracerebroventricular leptin increases lumbar and renal sympathetic nerve activity and blood pressure in normal rats. Diabetes 46: 2040-2043.
    • (1997) Diabetes , vol.46 , pp. 2040-2043
    • Dunbar, J.C.1    Hu, Y.2    Lu, H.3
  • 11
  • 12
    • 0033082380 scopus 로고    scopus 로고
    • From lesions to leptin: Hypothalamic control of food intake and body weight
    • Elmquist, J.E., C.F. Elias, and C.B. Saper. 1999. From lesions to leptin: Hypothalamic control of food intake and body weight. Neuron 22: 221-232.
    • (1999) Neuron , vol.22 , pp. 221-232
    • Elmquist, J.E.1    Elias, C.F.2    Saper, C.B.3
  • 14
    • 0031010408 scopus 로고    scopus 로고
    • Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues
    • Fei, H., H.J. Okano, C. Li, G.-H. Lee, C. Zhao, R. Darnell, and J.M. Friedman. 1997. Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. Proc. Natl. Acad. Sci. 94: 7001-7005.
    • (1997) Proc. Natl. Acad. Sci. , vol.94 , pp. 7001-7005
    • Fei, H.1    Okano, H.J.2    Li, C.3    Lee, G.-H.4    Zhao, C.5    Darnell, R.6    Friedman, J.M.7
  • 15
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman, J.M. and J.L. Halaas. 1998. Leptin and the regulation of body weight in mammals. Nature 395: 763-770.
    • (1998) Nature , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 16
    • 0026696804 scopus 로고
    • Genetic regulation of fatty acid synthase expression in adipose tissue: Overtranscription of the gene in genetically obese rats
    • Guichard, C., I. Dugail, X. Le Liepvre, and M. Lavau. 1992. Genetic regulation of fatty acid synthase expression in adipose tissue: Overtranscription of the gene in genetically obese rats. J. Lipid Res. 33: 679-687.
    • (1992) J. Lipid Res. , vol.33 , pp. 679-687
    • Guichard, C.1    Dugail, I.2    Le Liepvre, X.3    Lavau, M.4
  • 22
    • 0028862371 scopus 로고
    • A eukaryotic transcriptional repressor with carboxypeptidase activity
    • He, G.P., A. Muise, A.W. Li, and H.S. Ro. 1995. A eukaryotic transcriptional repressor with carboxypeptidase activity. Nature 378: 92-96.
    • (1995) Nature , vol.378 , pp. 92-96
    • He, G.P.1    Muise, A.2    Li, A.W.3    Ro, H.S.4
  • 23
    • 0032578453 scopus 로고    scopus 로고
    • Abnormal regulation of the leptin gene in the pathogenesis of obesity
    • Ioffe, E., B. Moon, E. Connolly, and J.M. Friedman. 1998. Abnormal regulation of the leptin gene in the pathogenesis of obesity. Proc. Natl. Acad. Sci. 95: 11852-11857.
    • (1998) Proc. Natl. Acad. Sci. , vol.95 , pp. 11852-11857
    • Ioffe, E.1    Moon, B.2    Connolly, E.3    Friedman, J.M.4
  • 24
    • 0030847432 scopus 로고    scopus 로고
    • Acute intravenous and intracerebroventricular leptin infusion increases glucose uptake and glucose turnover by an insulin independent mechanism
    • Kamohara, S., R. Burcelin, J.L. Halaas, J.M. Friedman, and M.J. Charron. 1997. Acute intravenous and intracerebroventricular leptin infusion increases glucose uptake and glucose turnover by an insulin independent mechanism. Nature 389: 374-377.
    • (1997) Nature , vol.389 , pp. 374-377
    • Kamohara, S.1    Burcelin, R.2    Halaas, J.L.3    Friedman, J.M.4    Charron, M.J.5
  • 25
    • 0032516081 scopus 로고    scopus 로고
    • ADD1/SREBP1 activates PPARgamma thorugh the production of endogenous ligand
    • Kim, J.B., H.M. Wright, M. Wright, and B.M. Spiegelman. 1998. ADD1/SREBP1 activates PPARgamma thorugh the production of endogenous ligand. Proc. Natl. Acad. Sci. 95: 4333-4337.
    • (1998) Proc. Natl. Acad. Sci. , vol.95 , pp. 4333-4337
    • Kim, J.B.1    Wright, H.M.2    Wright, M.3    Spiegelman, B.M.4
  • 26
    • 0003410791 scopus 로고    scopus 로고
    • 2nd ed, Springer series in information sciences. Berlin, Germany
    • Kohonen, T. 1997. Self-organizing maps. Vol. 426, 2nd ed, Springer series in information sciences. Berlin, Germany.
    • (1997) Self-organizing Maps , vol.426
    • Kohonen, T.1
  • 29
    • 0029939065 scopus 로고    scopus 로고
    • Decreased food intake does not completely account for adiposity reduction after ob protein infusion
    • Levin, N., C. Nelson, A. Gurney, R. Vandlen, and F. de Sauvage. 1996. Decreased food intake does not completely account for adiposity reduction after ob protein infusion. Proc. Natl. Acad. Sci. 93: 1726-1730.
    • (1996) Proc. Natl. Acad. Sci. , vol.93 , pp. 1726-1730
    • Levin, N.1    Nelson, C.2    Gurney, A.3    Vandlen, R.4    De Sauvage, F.5
  • 30
    • 0032572722 scopus 로고    scopus 로고
    • Leptin modulates the T-cell immune response and reverses starvation induced immunosuppression
    • Lord, G. 1998. Leptin modulates the T-cell immune response and reverses starvation induced immunosuppression. Nature 394: 897-891.
    • (1998) Nature , vol.394 , pp. 897-1891
    • Lord, G.1
  • 33
    • 0032475889 scopus 로고    scopus 로고
    • Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins
    • Pai, J.T., O. Guryev, M.S. Brown, and J.L. Goldstein. 1998. Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins. J. Biol. Chem. 273: 26138-26148.
    • (1998) J. Biol. Chem. , vol.273 , pp. 26138-26148
    • Pai, J.T.1    Guryev, O.2    Brown, M.S.3    Goldstein, J.L.4
  • 35
    • 0028815382 scopus 로고
    • Evidence of increased glyceraldehyde-3-phosphate dehydrogenase and fatty acid synthetase promoter activities in transiently transfected adipocytes from genetically obese rats
    • Rolland, V., I. Dugail, X. Le Lepvre, and M. Lavau. 1995. Evidence of increased glyceraldehyde-3-phosphate dehydrogenase and fatty acid synthetase promoter activities in transiently transfected adipocytes from genetically obese rats. J. Biol. Chem. 270: 1102-1106.
    • (1995) J. Biol. Chem. , vol.270 , pp. 1102-1106
    • Rolland, V.1    Dugail, I.2    Le Lepvre, X.3    Lavau, M.4
  • 38
    • 0032567445 scopus 로고    scopus 로고
    • Nuclear sterol regulatory element-binding proteins activate genes responsible for the entire program of unsaturated fatty acid biosynthesis in transgenic mouse liver
    • Shimomura, I., H. Shimano, B.S. Korn, Y. Bashmakov, and J.D. Horton. 1998. Nuclear sterol regulatory element-binding proteins activate genes responsible for the entire program of unsaturated fatty acid biosynthesis in transgenic mouse liver. J. Biol. Chem. 273: 35299-35306.
    • (1998) J. Biol. Chem. , vol.273 , pp. 35299-35306
    • Shimomura, I.1    Shimano, H.2    Korn, B.S.3    Bashmakov, Y.4    Horton, J.D.5
  • 39
    • 0343339645 scopus 로고    scopus 로고
    • Soukas et al.
    • Soukas et al.
  • 40
    • 0033570119 scopus 로고    scopus 로고
    • Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus
    • Shimomura, I., Y. Bashmakov, and J.D. Horton. 1999. Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus. J. Biol. Chem. 274: 30028-30032.
    • (1999) J. Biol. Chem. , vol.274 , pp. 30028-30032
    • Shimomura, I.1    Bashmakov, Y.2    Horton, J.D.3
  • 43
    • 0032555479 scopus 로고    scopus 로고
    • Transcriptional activation of the stearoyl-CoA desaturase 2 gene by sterol regulatory element-binding protein/adipocyte determination and differentiation factor 1
    • Tabor, E., J.B. Kim, B.M. Spiegelman, and P.A. Edwards. 1998. Transcriptional activation of the stearoyl-CoA desaturase 2 gene by sterol regulatory element-binding protein/adipocyte determination and differentiation factor 1. J. Biol. Chem. 273: 22052-22058.
    • (1998) J. Biol. Chem. , vol.273 , pp. 22052-22058
    • Tabor, E.1    Kim, J.B.2    Spiegelman, B.M.3    Edwards, P.A.4
  • 44
    • 0033027794 scopus 로고    scopus 로고
    • Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation
    • Tamayo, P., D. Slonim, J. Mesirov, Q. Zhu, S. Kitareewan, E. Dmitrovsky, E.S. Lander, and T.R. Golub. 1999. Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation. Proc. Natl. Acad. Sci. 96: 2907-2912.
    • (1999) Proc. Natl. Acad. Sci. , vol.96 , pp. 2907-2912
    • Tamayo, P.1    Slonim, D.2    Mesirov, J.3    Zhu, Q.4    Kitareewan, S.5    Dmitrovsky, E.6    Lander, E.S.7    Golub, T.R.8
  • 46
    • 0027648820 scopus 로고
    • ADD1: A novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation
    • Tontonoz, P., J.B. Kim, R.A. Graves, and B.M. Spiegelman. 1993. ADD1: A novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation. Mol. Cell. Biol. 13: 4753-4759.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4753-4759
    • Tontonoz, P.1    Kim, J.B.2    Graves, R.A.3    Spiegelman, B.M.4
  • 47
    • 0028828951 scopus 로고
    • Identification and characterization of an immunophilin expressed during the clonal expansion phase of adipocyte differentiation
    • Yeh, W.C., T.C. Li, B.E. Bierer, and S.L. McKnight. 1995. Identification and characterization of an immunophilin expressed during the clonal expansion phase of adipocyte differentiation. Proc. Natl. Acad. Sci. 92: 11081-11085.
    • (1995) Proc. Natl. Acad. Sci. , vol.92 , pp. 11081-11085
    • Yeh, W.C.1    Li, T.C.2    Bierer, B.E.3    McKnight, S.L.4
  • 48
    • 0027490174 scopus 로고
    • SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene
    • Yokoyama, C., X. Wang, M.R. Briggs, A. Admon, J. Wu, X. Hua, J.L. Goldstein, and M.S. Brown. 1993. SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene. Cell 75: 187-197.
    • (1993) Cell , vol.75 , pp. 187-197
    • Yokoyama, C.1    Wang, X.2    Briggs, M.R.3    Admon, A.4    Wu, J.5    Hua, X.6    Goldstein, J.L.7    Brown, M.S.8
  • 49
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • Zhang, Y., P. Proenca, M. Maffei, M. Barone, L. Leopold, and J.M. Friedman. 1994. Positional cloning of the mouse obese gene and its human homologue. Nature 372: 425-432.
    • (1994) Nature , vol.372 , pp. 425-432
    • Zhang, Y.1    Proenca, P.2    Maffei, M.3    Barone, M.4    Leopold, L.5    Friedman, J.M.6
  • 51
    • 0033514948 scopus 로고    scopus 로고
    • Reversing adipocyte differentiation: Implications for treatment of obesity
    • Zhou, Y.T., Z.W. Wang, M. Higa, C.B. Newgard, and R.H. Unger. 1999. Reversing adipocyte differentiation: Implications for treatment of obesity. Proc. Natl. Acad. Sci. 96: 2391-2395.
    • (1999) Proc. Natl. Acad. Sci. , vol.96 , pp. 2391-2395
    • Zhou, Y.T.1    Wang, Z.W.2    Higa, M.3    Newgard, C.B.4    Unger, R.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.