Polyunsaturated fatty acids of marine origin induce adiponectin in mice fed a high-fat diet

Diabetologia

Volumn 49, Issue 2, 2006, Pages 394-397

  Flachs, P ^a   Mohamed Ali, V ^b   Horakova, O ^a   Rossmeisl, M ^a   Hosseinzadeh Attar, M J ^b   Hensler, M ^a   Ruzickova, J ^a   Kopecky, J ^a  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Adipokines; Adiponectin; Adipose tissue; Fish oil; High fat diet; n 3 PUFA

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; DOCOSAHEXAENOIC ACID; GLUCOSE; ICOSAPENTAENOIC ACID; INSULIN SENSITIZING AGENT; LEPTIN; POLYUNSATURATED FATTY ACID; TRIACYLGLYCEROL; VEGETABLE OIL;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALORIC RESTRICTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIET RESTRICTION; DIETARY INTAKE; DRUG EFFECT; EPIDIDYMIS FAT; FOOD INTAKE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HORMONE RELEASE; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; LIPID DIET; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL; WHITE ADIPOSE TISSUE;

ADIPOCYTES; ADIPONECTIN; ADIPOSE TISSUE; ANIMALS; BODY COMPOSITION; CALORIC RESTRICTION; DIETARY FATS; DOCOSAHEXAENOIC ACIDS; EATING; EICOSAPENTAENOIC ACID; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GLUCOSE; INSULIN; INSULIN RESISTANCE; LEPTIN; MALE; MICE; MICE, INBRED C57BL; OBESITY; PROTEIN KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRIGLYCERIDES;

EID: 31844451413     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-005-0053-y     Document Type: Article

References (11)

1. Ruzickova J, Rossmeisl M, Prazak T et al (2004) Omega-3 PUFA of marine origin limit diet-induced obesity in mice by reducing cellularity of adipose tissue. Lipids 39:1177-1185
2. Ruxton CH, Reed SC, Simpson MJ, Millington KJ (2004) The health benefits of omega-3 polyunsaturated fatty acids: a review of the evidence. J Hum Nutr Diet 17:449-459
3. Delarue J, LeFoll C, Corporeau C, Lucas D (2004) N-3 long chain polyunsaturated fatty acids: a nutritional tool to prevent insulin resistance associated to type 2 diabetes and obesity? Reprod Nutr Dev 44:289-299
4. Flachs P, Horakova O, Brauner P et al (2005) Polyunsaturated fatty acids of marine origin upregulate mitochondrial biogenesis and induce beta-oxidation in white fat. Diabetologia 48:2365-2375
5. Yamauchi T, Kamon J, Minokoshi Y et al (2002) Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 8:1288-1295
6. Arita Y, Kihara S, Ouchi N et al (1999) Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 257:79-83
7. Wellhoener P, Fruehwald-Schultes B, Kern W et al (2000) Glucose metabolism rather than insulin is a main determinant of leptin secretion in humans. J Clin Endocrinol Metab 85:1267-1271
8. Iwaki M, Matsuda M, Maeda N et al (2003). Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors. Diabetes 52:1655-1663
9. Lihn AS, Jessen N, Pedersen SB, Lund S, Richelsen B (2004) AICAR stimulates adiponectin and inhibits cytokines in adipose tissue. Biochem Biophys Res Commun 316:853-858
10. Suchankova G, Tekle M, Saha AK, Ruderman NB, Clarke SD, Gettys TW (2005) Dietary polyunsaturated fatty acids enhance hepatic AMP-activated protein kinase activity in rats. Biochem Biophys Res Commun 326:851-858
11. Fernandez-Real JM, Vendrell J, Ricart W (2005) Circulating adiponectin and plasma fatty acid profile. Clin Chem 51:603-609