DHA inhibits protein degradation more efficiently than EPA by regulating the PPAR γ /NF B pathway in C2C12 myotubes

BioMed Research International

Volumn 2013, Issue , 2013, Pages

  Wang, Yue ^a   Lin, Qiao Wei ^a   Zheng, Pei Pei ^a   Zhang, Jian Song ^a   Huang, Fei Ruo ^a  

^a HUAZHONG AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE SERUM ALBUMIN; DNA BINDING PROTEIN; DOCOSAHEXAENOIC ACID; I KAPPA B ALPHA; ICOSAPENTAENOIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OMEGA 3 FATTY ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN; I KAPPA B; NF-KAPPAB INHIBITOR ALPHA; NF KAPPAB INHIBITOR ALPHA;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LINE; CONTROLLED STUDY; DNA BINDING; DRUG INHIBITION; DRUG MECHANISM; MYOBLAST; MYOTUBE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOUSE; RNA INTERFERENCE; SKELETAL MUSCLE; DRUG EFFECT;

ANIMALS; DOCOSAHEXAENOIC ACIDS; EICOSAPENTAENOIC ACID; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; I-KAPPA B PROTEINS; MICE; MUSCLE FIBERS, SKELETAL; NF-KAPPA B; PPAR GAMMA; PROTEOLYSIS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84883204089     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2013/318981     Document Type: Article

References (22)

1. Li H., Malhotra S., Kumar A., Nuclear factor-kappa B signaling in skeletal muscle atrophy. Journal of Molecular Medicine 2008 86 10 1113 1126 2-s2.0-52549133171 10.1007/s00109-008-0373-8
2. Schreiber S., Nikolaus S., Hampe J., Activation of nuclear factor B inflammatory bowel disease. Gut 1998 42 4 477 484 2-s2.0-0031925362
3. Jové M., Planavila A., Laguna J. C., Vázquez-Carrera M., Palmitate-induced interleukin 6 production is mediated by protein kinase C and nuclear-factor B activation and leads to glucose transporter 4 down-regulation in skeletal muscle cells. Endocrinology 2005 146 7 3087 3095 2-s2.0-22144498471 10.1210/en.2004-1560
4. Chung S., Brown J. M., Provo J. N., Hopkins R., McIntosh M. K., Conjugated linoleic acid promotes human adipocyte insulin resistance through NF B-dependent cytokine production. The Journal of Biological Chemistry 2005 280 46 38445 38456 2-s2.0-33644680390 10.1074/jbc.M508159200
5. Li Y.-P., Schwartz R. J., Waddell I. D., Holloway B. R., Reid M. B., Skeletal muscle myocytes undergo protein loss and reactive oxygen- mediated NF- B activation in response to tumor necrosis factor α FASEB Journal 1998 12 10 871 880 2-s2.0-0031802331
6. Tracey K. J., Wei H., Manogue K. R., Fong Y., Hesse D. G., Nguyen H. T., Kuo G. C., Beutler B., Cotran R. S., Cerami A., Lowry S. F., Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation. Journal of Experimental Medicine 1988 167 3 1211 1227 2-s2.0-0023916786
7. Reid M. B., Response of the ubiquitin-proteasome pathway to changes in muscle activity. American Journal of Physiology 2005 288 6 R1423 R1431 2-s2.0-19344372609 10.1152/ajpregu.00545.2004
8. Castillero E., Martín A. I., López-Menduiña M., Villana M. A., López-Calderón A., Eicosapentaenoic acid attenuates arthritis-induced muscle wasting acting on atrogin-1 and on myogenic regulatory factors. American Journal of Physiology 2009 297 5 R1331 R1322
9. Hommelberg P. P. H., Plat J., Langen R. C. J., Schols A. M. W. J., Mensink R. P., Fatty acid-induced NF- B activation and insulin resistance in skeletal muscle are chain length dependent. American Journal of Physiology 2009 296 1 E114 E120 2-s2.0-58249096193 10.1152/ajpendo.00436.2007
10. Tisdale M. J., Inhibition of lipolysis and muscle protein degradation by EPA in cancer cachexia. Nutrition 1996 12 supplement 1 S31 S33 2-s2.0-0029926812
11. Whitehouse A. S., Smith H. J., Drake J. L., Tisdale M. J., Mechanism of attenuation of skeletal muscle protein catabolism in cancer cachexia by eicosapentaenoic acid. Cancer Research 2001 61 9 3604 3609 2-s2.0-0035328839
12. Smith H. J., Greenberg N. A., Tisdale M. J., Effect of eicosapentaenoic acid, protein and amino acids on protein synthesis and degradation in skeletal muscle of cachectic mice. British Journal of Cancer 2004 91 2 408 412 2-s2.0-3843054746
13. Huang F., Wei H., Luo H., Jiang S., Peng J., EPA inhibits the inhibitor of Ba (I Ba)/NF- B/muscle RING finger 1 pathway in C2C12 myotubes in a PPAR γ -dependent manner. British Journal of Nutrition 2011 105 3 348 356
14. Kim Y. K., Hyun S. C., Won H. J., Sung S. K., Hyae G. C., Phosphatase and tensin homolog deleted on chromosome 10 suppression is an important process in peroxisome proliferator-activated receptor- β signaling in adipocytes and myotubes. Molecular Pharmacology 2007 71 6 1554 1562 2-s2.0-34347353323 10.1124/mol.106.031948
15. Chavez J. A., Knotts T. A., Wang L.-P., Li G., Dobrowsky R. T., Florant G. L., Summers S. A., A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids. The Journal of Biological Chemistry 2003 278 12 10297 10303 2-s2.0-0038532298 10.1074/jbc.M212307200
16. Desler M. M., Jones S. J., Smith C. W., Woods T. L., Effects of dexamethasone and anabolic agents on proliferation and protein synthesis and degradation in C2C12 myogenic cells. Journal of Animal Science 1996 74 6 1265 1273 2-s2.0-0030155985
17. Andrews N. C., Faller D. V., A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Research 1991 19 9 2499 2-s2.0-0025730640
18. Babcock T., Helton W. S., Espat N. J., Eicosapentaenoic acid (EPA): an antiinflammatory ω -3 fat with potential clinical applications. Nutrition 2000 16 11-12 1116 1118 2-s2.0-0033665278 10.1016/S0899-9007(00)00392-0
19. Lo C.-J., Chiu K. C., Fu M., Lo R., Helton S., Fish oil decreases macrophage tumor necrosis factor gene transcription by altering the NF B activity. Journal of Surgical Research 1999 82 2 216 221 2-s2.0-0032817672 10.1006/jsre.1998.5524
20. Gao Z., He Q., Peng B., Chiao P. J., Ye J., Regulation of nuclear translocation of HDAC3 by I B α is required for tumor necrosis factor inhibition of peroxisome proliferator- activated receptor γ function. The Journal of Biological Chemistry 2006 281 7 4540 4547 2-s2.0-33645225429 10.1074/jbc.M507784200
21. Remels A. H. V., Langen R. C. J., Gosker H. R., Russell A. P., Spaapen F., Voncken J. W., Schrauwen P., Schols A. M. W. J., PPAR γ inhibits NF- B-dependent transcriptional activation in skeletal muscle. American Journal of Physiology 2009 297 1 E174 E183 2-s2.0-67650034885 10.1152/ajpendo.90632.2008
22. Li H., Ruan X. Z., Powis S. H., Fernando R., Mon W. Y., Wheeler D. C., Moorhead J. F., Varghese Z., EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: evidence for a PPAR- γ -dependent mechanism. Kidney International 2005 67 3 867 874 2-s2.0-20844440063 10.1111/j.1523-1755. 2005.00151.x