Electrophilic nitro-fatty acids inhibit vascular inflammation by disrupting LPS-dependent TLR4 signalling in lipid rafts

Cardiovascular Research

Volumn 98, Issue 1, 2013, Pages 116-124

  Villacorta, Luis ^a   Chang, Lin ^a   Salvatore, Sonia R ^b   Ichikawa, Tomonaga ^a,c   Zhang, Jifeng ^a   Petrovic Djergovic, Danica ^a   Jia, Lingyun ^a,d   Carlsen, Harald ^e   Schopfer, Francisco J ^b   A Freeman, Bruce ^b   Chen, Y Eugene ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MIYAZAKI   (Japan)

^d CAPITAL MEDICAL UNIVERSITY   (China)

^e UNIVERSITY OF OSLO   (Norway)

Author keywords

Inflammation; Lipid rafts; NF kB; Nitro fatty acids; TLR4

Indexed keywords

CELL ADHESION MOLECULE; FATTY ACID DERIVATIVE; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; NITRITE; NITRO OLEIC ACID; OLEIC ACID; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; AORTA; ARTICLE; CELL SURFACE; CONTROLLED STUDY; ELECTROPHILICITY; HEART LEFT VENTRICLE PRESSURE; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE; LIPID RAFT; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UBIQUITINATION; VASCULAR ENDOTHELIUM; VASCULITIS;

ANIMALS; CELL ADHESION; CELLS, CULTURED; HUMANS; LIPOPOLYSACCHARIDES; MEMBRANE MICRODOMAINS; MICE; MICE, INBRED C57BL; NF-KAPPA B; NITRIC OXIDE; OLEIC ACIDS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; VASCULITIS;

EID: 84875204850     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvt002     Document Type: Article

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