Interleukin-1F7b (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7b binds to the IL-18 receptor but does not induce IFN-γ production

Cytokine

Volumn 18, Issue 2, 2002, Pages 61-71

  Kumar, Sanjay ^a   Hanning, Charles R ^a   Rieman, David J ^a   Lee, John C ^a   Lotze, Michael T ^a   Brigham Burke, Michael R ^a   Lehr, Ruth ^a   Khandekar, Sanjay ^a   Kirkpatrick, Robert B ^a   Scott, Gilbert F ^a   Lynch, Frank J ^b   Gao, Wentao ^c   Gambotto, Andrea ^c  

^a GLAXOSMITHKLINE   (United States)

^b Qualtek Molecular Labs   (United States)

^c UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

Caspase 1; Homologues; Inflammation; Interleukin; Processing

Indexed keywords

CASPASE; CASPASE 4; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 1 DERIVATIVE; INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 1F7B; UNCLASSIFIED DRUG; COMPLEMENTARY DNA; HYBRID PROTEIN; IL18R1 PROTEIN, HUMAN; INTERLEUKIN 1; INTERLEUKIN 1 HOMOLOG 4, HUMAN; INTERLEUKIN 18 RECEPTOR ALPHA; INTERLEUKIN RECEPTOR; INTERLEUKIN-1 HOMOLOG 4, HUMAN;

ADENOVIRUS; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL POPULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SEQUENCE HOMOLOGY; BINDING SITE; BIOSYNTHESIS; CELL LINE; GENETICS; METABOLISM;

ADENOVIRIDAE;

AMINO ACID SEQUENCE; BINDING SITES; CASPASE 1; CASPASES; CELL LINE; DNA, COMPLEMENTARY; HUMANS; INTERFERON TYPE II; INTERLEUKIN-1; INTERLEUKIN-18; INTERLEUKIN-18 RECEPTOR ALPHA SUBUNIT; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-18; RECOMBINANT FUSION PROTEINS;

EID: 0036020218     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.2002.0873     Document Type: Article

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