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Volumn 59, Issue 2, 2010, Pages 143-160

IL-33 and IL-33 receptors in host defense and diseases

Author keywords

Allergy; Autoimmunity; Basophil; Chronic disease; Eosinophil; Host defense; IL 33; Mast cell; ST2

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 13; INTERLEUKIN 33; INTERLEUKIN 33 RECEPTOR; INTERLEUKIN 5; INTERLEUKIN RECEPTOR; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; IL1RL1 PROTEIN, HUMAN; IL1RL1 PROTEIN, MOUSE; IL33 PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE; TOLL LIKE RECEPTOR;

EID: 77954555721     PISSN: 13238930     EISSN: 14401592     Source Type: Journal    
DOI: 10.2332/allergolint.10-RAI-0186     Document Type: Review
Times cited : (183)

References (154)
  • 1
    • 0033510084 scopus 로고    scopus 로고
    • Identification of genes differentially expressed in canine vasospastic cerebral arteries after subarachnoid hemorrhage
    • Onda H, Kasuya H, Takakura K et al. Identification of genes differentially expressed in canine vasospastic cerebral arteries after subarachnoid hemorrhage. J Cereb Blood Flow Metab 1999;19:1279-88.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 1279-1288
    • Onda, H.1    Kasuya, H.2    Takakura, K.3
  • 2
    • 0037631696 scopus 로고    scopus 로고
    • Molecular characterization of NF-HEV, a nuclear factor preferentially expressedinhuman high endothelial venules
    • Baekkevold ES, Roussigne M, Yamanaka T et al. Molecu-lar characterization of NF-HEV, a nuclear factor preferentially expressedinhuman high endothelial venules. Am J Pathol 2003;163:69-79.
    • (2003) Am J Pathol , vol.163 , pp. 69-79
    • Baekkevold, E.S.1    Roussigne, M.2    Yamanaka, T.3
  • 3
    • 27744446058 scopus 로고    scopus 로고
    • IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
    • Schmitz J, Owyang A, Oldham E et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 2005;23:479-90.
    • (2005) Immunity , vol.23 , pp. 479-490
    • Schmitz, J.1    Owyang, A.2    Oldham, E.3
  • 4
    • 76249084409 scopus 로고    scopus 로고
    • Caspase-1, caspase-8, and calpain are dispensable for IL-33 release by macrophages
    • Ohno T, Oboki K, Kajiwara N et al. Caspase-1, caspase-8, and calpain are dispensable for IL-33 release by macrophages. J Immunol 2009;183:7890-7.
    • (2009) J Immunol , vol.183 , pp. 7890-7897
    • Ohno, T.1    Oboki, K.2    Kajiwara, N.3
  • 5
    • 33846101552 scopus 로고    scopus 로고
    • IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo
    • Carriere V, Roussel L, Ortega N et al. IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo. Proc Natl Acad Sci U S A 2007;104:282-7.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 282-287
    • Carriere, V.1    Roussel, L.2    Ortega, N.3
  • 6
    • 53249093714 scopus 로고    scopus 로고
    • Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A-H2B acidic pocket
    • Roussel L, Erard M, Cayrol C, Girard JP. Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A-H2B acidic pocket. EMBO Rep 2008; 9:1006-12.
    • (2008) EMBO Rep , vol.9 , pp. 1006-1012
    • Roussel, L.1    Erard, M.2    Cayrol, C.3    Girard, J.P.4
  • 8
    • 36749067367 scopus 로고    scopus 로고
    • IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells
    • Ali S, Huber M, Kollewe C, Bischoff SC, Falk W, Martin MU. IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells. Proc Natl Acad Sci USA 2007;104:18660-5.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 18660-18665
    • Ali, S.1    Huber, M.2    Kollewe, C.3    Bischoff, S.C.4    Falk, W.5    Martin, M.U.6
  • 9
    • 55149105005 scopus 로고    scopus 로고
    • The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress
    • O'Neill LA. The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress. Immunol Rev 2008; 226:10-8.
    • (2008) Immunol Rev , vol.226 , pp. 10-18
    • O'Neill, L.A.1
  • 10
    • 47249089097 scopus 로고    scopus 로고
    • IL-1, IL-18, and IL-33 families of cytokines
    • Arend WP, Palmer G, Gabay C. IL-1, IL-18, and IL-33 families of cytokines. Immunol Rev 2008;223:20-38.
    • (2008) Immunol Rev , vol.223 , pp. 20-38
    • Arend, W.P.1    Palmer, G.2    Gabay, C.3
  • 11
    • 62649139025 scopus 로고    scopus 로고
    • Immunological and inflammatory functions of the interleukin-1 family
    • Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol 2009;27: 519-50.
    • (2009) Annu Rev Immunol , vol.27 , pp. 519-550
    • Dinarello, C.A.1
  • 12
    • 0033198885 scopus 로고    scopus 로고
    • Different promoter usage and multiple transcription initiation sites of the interleukin-1 receptor-related human ST2 gene in UT-7 and TM12 cells
    • Iwahana H, Yanagisawa K, Ito-Kosaka A et al. Different promoter usage and multiple transcription initiation sites of the interleukin-1 receptor-related human ST2 gene in UT-7 and TM12 cells. Eur J Biochem 1999;264:397-406.
    • (1999) Eur J Biochem , vol.264 , pp. 397-406
    • Iwahana, H.1    Yanagisawa, K.2    Ito-Kosaka, A.3
  • 13
    • 0034807091 scopus 로고    scopus 로고
    • Tissue distribution and subcellular localization of a variant form of the human ST2 gene product, ST2V
    • Tago K, Noda T, Hayakawa M et al. Tissue distribution and subcellular localization of a variant form of the human ST2 gene product, ST2V. Biochem Biophys Res Commun 2001;285:1377-83.
    • (2001) Biochem Biophys Res Commun , vol.285 , pp. 1377-1383
    • Tago, K.1    Noda, T.2    Hayakawa, M.3
  • 14
    • 9244222725 scopus 로고    scopus 로고
    • Molecular cloning of the chicken ST2 gene and a novel variant form of the ST2 gene product, ST2LV
    • Iwahana H, Hayakawa M, Kuroiwa K et al. Molecular cloning of the chicken ST2 gene and a novel variant form of the ST2 gene product, ST2LV. Biochim Biophys Acta 2004;1681:1-14.
    • (2004) Biochim Biophys Acta , vol.1681 , pp. 1-14
    • Iwahana, H.1    Hayakawa, M.2    Kuroiwa, K.3
  • 15
    • 64849087206 scopus 로고    scopus 로고
    • The essential role of single Ig IL-1 receptor-related molecule/Toll IL-1R8 in regulation of Th2 immune response
    • Bulek K, Swaidani S, Qin J et al. The essential role of single Ig IL-1 receptor-related molecule/Toll IL-1R8 in regulation of Th2 immune response. J Immunol 2009;182: 2601-9.
    • (2009) J Immunol , vol.182 , pp. 2601-2609
    • Bulek, K.1    Swaidani, S.2    Qin, J.3
  • 16
    • 68949181883 scopus 로고    scopus 로고
    • TIR8/SIGIRR: An IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization
    • Garlanda C, Anders HJ, Mantovani A. TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization. Trends Immunol 2009; 30:439-46.
    • (2009) Trends Immunol , vol.30 , pp. 439-446
    • Garlanda, C.1    Anders, H.J.2    Mantovani, A.3
  • 17
    • 12144287484 scopus 로고    scopus 로고
    • Intestinal Inflammation In Mice Deficient In Tir8, An Inhibitory Member of TheIL-1receptorfamily
    • Garlanda C, Riva F, Polentarutti N et al. Intestinal inflammation in mice deficient in Tir8, an inhibitory member of theIL-1receptorfamily. Proc Natl Acad Sci U S A 2004; 101:3522-6.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 3522-3526
    • Garlanda, C.1    Riva, F.2    Polentarutti, N.3
  • 18
    • 0036772860 scopus 로고    scopus 로고
    • Activated, but not resting human Th2 cells, in contrast to Th1 and T regulatory cells, produce soluble ST2 and express low levels of ST2L at the cell surface
    • Lecart S, Lecointe N, Subramaniam A et al. Activated, but not resting human Th2 cells, in contrast to Th1 and T regulatory cells, produce soluble ST2 and express low levels of ST2L at the cell surface. Eur J Immunol 2002;32: 2979-87.
    • (2002) Eur J Immunol , vol.32 , pp. 2979-2987
    • Lecart, S.1    Lecointe, N.2    Subramaniam, A.3
  • 19
    • 0032499678 scopus 로고    scopus 로고
    • T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function
    • Lohning M, Stroehmann A, Coyle AJ et al. T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function. Proc Natl Acad Sci U S A 1998;95:6930-5.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 6930-6935
    • Lohning, M.1    Stroehmann, A.2    Coyle, A.J.3
  • 20
    • 34247895422 scopus 로고    scopus 로고
    • Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17
    • Nakae S, Iwakura Y, Suto H, Galli SJ. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J Leukoc Biol 2007;81:1258-68.
    • (2007) J Leukoc Biol , vol.81 , pp. 1258-1268
    • Nakae, S.1    Iwakura, Y.2    Suto, H.3    Galli, S.J.4
  • 21
    • 0033570791 scopus 로고    scopus 로고
    • Theab-sence of interleukin 1 receptor-related T1/ST2 does not affect T helper cell type 2 development and its effector function
    • Hoshino K, Kashiwamura S, Kuribayashi K et al. Theab-sence of interleukin 1 receptor-related T1/ST2 does not affect T helper cell type 2 development and its effector function. J Exp Med 1999;190:1541-8.
    • (1999) J Exp Med , vol.190 , pp. 1541-1548
    • Hoshino, K.1    Kashiwamura, S.2    Kuribayashi, K.3
  • 22
    • 0034689033 scopus 로고    scopus 로고
    • T1/ST2-deficient mice demonstrate the importance ofT1/ST2 in developing primary T helper cell type 2 responses
    • Townsend MJ, Fallon PG, Matthews DJ, Jolin HE, McKenzie AN. T1/ST2-deficient mice demonstrate the importance ofT1/ST2 in developing primary T helper cell type 2 responses. J Exp Med 2000;191:1069-76.
    • (2000) J Exp Med , vol.191 , pp. 1069-1076
    • Townsend, M.J.1    Fallon, P.G.2    Matthews, D.J.3    Jolin, H.E.4    McKenzie, A.N.5
  • 23
    • 44849117539 scopus 로고    scopus 로고
    • Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system
    • Kondo Y, Yoshimoto T, Yasuda K et al. Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system. Int Immunol 2008;20:791-800.
    • (2008) Int Immunol , vol.20 , pp. 791-800
    • Kondo, Y.1    Yoshimoto, T.2    Yasuda, K.3
  • 24
    • 58149300244 scopus 로고    scopus 로고
    • IL-33 induces antigen-specific IL-5+ T cells and promotes allergic-induced airway inflammation independent of IL-4
    • Kurowska-Stolarska M, Kewin P, Murphy G et al. IL-33 induces antigen-specific IL-5+ T cells and promotes allergic-induced airway inflammation independent of IL-4. J Immunol 2008;181:4780-90.
    • (2008) J Immunol , vol.181 , pp. 4780-4790
    • Kurowska-Stolarska, M.1    Kewin, P.2    Murphy, G.3
  • 25
    • 69449106110 scopus 로고    scopus 로고
    • IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells
    • Guo L, Wei G, Zhu J et al. IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells. Proc Natl Acad Sci USA 2009;106:13463-8.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 13463-13468
    • Guo, L.1    Wei, G.2    Zhu, J.3
  • 26
    • 61849117309 scopus 로고    scopus 로고
    • Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33
    • Pecaric-Petkovic T, Didichenko SA, Kaempfer S, Spiegl N, Dahinden CA. Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. Blood 2009;113:1526-34.
    • (2009) Blood , vol.113 , pp. 1526-1134
    • Pecaric-Petkovic, T.1    Didichenko, S.A.2    Kaempfer, S.3    Spiegl, N.4    Dahinden, C.A.5
  • 27
    • 48449089903 scopus 로고    scopus 로고
    • IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells
    • Smithgall MD, Comeau MR, Yoon BR, Kaufman D, Armitage R, Smith DE. IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells. Int Immunol 2008;20:1019-30.
    • (2008) Int Immunol , vol.20 , pp. 1019-1030
    • Smithgall, M.D.1    Comeau, M.R.2    Yoon, B.R.3    Kaufman, D.4    Armitage, R.5    Smith, D.E.6
  • 29
    • 0032729433 scopus 로고    scopus 로고
    • Expression of Th2 cytokines and the stable Th2 marker ST2L in the absence of IL-4 during Leishmania major infection
    • Kropf P, Schopf LR, Chung CL et al. Expression of Th2 cytokines and the stable Th2 marker ST2L in the absence of IL-4 during Leishmania major infection. Eur J Immunol 1999;29:3621-8.
    • (1999) Eur J Immunol , vol.29 , pp. 3621-3628
    • Kropf, P.1    Schopf, L.R.2    Chung, C.L.3
  • 30
    • 0037378857 scopus 로고    scopus 로고
    • Signaling through the T1/ST2 molecule is not necessary for Th2 differentiation but is important for the regulation of type 1 responses in nonhealing Leishmania major infection
    • Kropf P, Herath S, Klemenz R, Muller I. Signaling through the T1/ST2 molecule is not necessary for Th2 differentiation but is important for the regulation of type 1 responses in nonhealing Leishmania major infection. Infect Immun 2003;71:1961-71.
    • (2003) Infect Immun , vol.71 , pp. 1961-1971
    • Kropf, P.1    Herath, S.2    Klemenz, R.3    Muller, I.4
  • 31
    • 0035423397 scopus 로고    scopus 로고
    • Human IL-18 receptor and ST2L are stable and selective markers for the respective type 1 and type 2 circulating lymphocytes
    • Chan WL, Pejnovic N, Lee CA, Al-Ali NA. Human IL-18 receptor and ST2L are stable and selective markers for the respective type 1 and type 2 circulating lymphocytes. J Immunol 2001;167:1238-44.
    • (2001) J Immunol , vol.167 , pp. 1238-1244
    • Chan, W.L.1    Pejnovic, N.2    Lee, C.A.3    Al-Ali, N.A.4
  • 32
    • 0037148511 scopus 로고    scopus 로고
    • Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: A novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis
    • McGuirk P, McCann C, Mills KH. Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis. J Exp Med 2002;195:221-31.
    • (2002) J Exp Med , vol.195 , pp. 221-231
    • McGuirk, P.1    McCann, C.2    Mills, K.H.3
  • 33
    • 0032212250 scopus 로고    scopus 로고
    • The IL-1 receptor-related T1 antigenisexpressedonimma-ture and mature mast cells and on fetal blood mast cell progenitors
    • Moritz DR, Rodewald HR, Gheyselinck J, Klemenz R. The IL-1 receptor-related T1 antigenisexpressedonimma-ture and mature mast cells and on fetal blood mast cell progenitors. J Immunol 1998; 161:4866-74.
    • (1998) J Immunol , vol.161 , pp. 4866-4874
    • Moritz, D.R.1    Rodewald, H.R.2    Gheyselinck, J.3    Klemenz, R.4
  • 35
    • 34548719890 scopus 로고    scopus 로고
    • IL-33 can promote survival, adhesion and cytokine production in human mast cells
    • Iikura M, Suto H, Kajiwara N et al. IL-33 can promote survival, adhesion and cytokine production in human mast cells. Lab Invest 2007;87:971-8.
    • (2007) Lab Invest , vol.87 , pp. 971-978
    • Iikura, M.1    Suto, H.2    Kajiwara, N.3
  • 36
    • 34848886843 scopus 로고    scopus 로고
    • Cutting edge: The ST2 ligand IL-33 potently activates and drives maturation of human mast cells
    • Allakhverdi Z, Smith DE, Comeau MR, Delespesse G. Cutting edge: The ST2 ligand IL-33 potently activates and drives maturation of human mast cells. J Immunol 2007; 179:2051-4.
    • (2007) J Immunol , vol.179 , pp. 2051-2054
    • Allakhverdi, Z.1    Smith, D.E.2    Comeau, M.R.3    Delespesse, G.4
  • 37
    • 37249049230 scopus 로고    scopus 로고
    • IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcepsilonRI signals
    • Ho LH, Ohno T, Oboki K et al. IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcepsilonRI signals. J Leukoc Biol 2007;82:1481-90.
    • (2007) J Leukoc Biol , vol.82 , pp. 1481-1490
    • Ho, L.H.1    Ohno, T.2    Oboki, K.3
  • 38
    • 36749026651 scopus 로고    scopus 로고
    • Interleukin (IL)-33 induces the release of proinflammatory mediators by mast cells
    • Moulin D, Donze O, Talabot-Ayer D, Mezin F, Palmer G, Gabay C. Interleukin (IL)-33 induces the release of proinflammatory mediators by mast cells. Cytokine 2007;40: 216-25.
    • (2007) Cytokine , vol.40 , pp. 216-225
    • Moulin, D.1    Donze, O.2    Talabot-Ayer, D.3    Mezin, F.4    Palmer, G.5    Gabay, C.6
  • 39
    • 67649852593 scopus 로고    scopus 로고
    • The cytokine interleukin-33 mediates anaphylactic shock
    • Pushparaj PN, Tay HK, H'Ng SC et al. The cytokine interleukin-33 mediates anaphylactic shock. Proc Natl Acad Sci USA 2009;106:9773-8.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9773-9778
    • Pushparaj, P.N.1    Tay, H.K.2    H'ng, S.C.3
  • 40
    • 33745668408 scopus 로고    scopus 로고
    • Basophils: A potential liaison between innate and adaptive immunity
    • Min B, Le Gros G, Paul WE. Basophils: a potential liaison between innate and adaptive immunity. Allergol Int 2006; 55:99-104.
    • (2006) Allergol Int , vol.55 , pp. 99-104
    • Min, B.1    Le Gros, G.2    Paul, W.E.3
  • 41
    • 58149218230 scopus 로고    scopus 로고
    • Basophils: A nonredundant contributor to host immunity
    • Sullivan BM, Locksley RM. Basophils: a nonredundant contributor to host immunity. Immunity 2009;30:12-20.
    • (2009) Immunity , vol.30 , pp. 12-20
    • Sullivan, B.M.1    Locksley, R.M.2
  • 42
    • 67649229687 scopus 로고    scopus 로고
    • MHC class II-dependent basophil-CD4+ T cell interactions promote T (H)2 cytokine-dependent immunity
    • Perrigoue JG, Saenz SA, Siracusa MC et al. MHC class II-dependent basophil-CD4+ T cell interactions promote T (H)2 cytokine-dependent immunity. Nat Immunol 2009; 10:697-705.
    • (2009) Nat Immunol , vol.10 , pp. 697-705
    • Perrigoue, J.G.1    Saenz, S.A.2    Siracusa, M.C.3
  • 43
    • 67649216604 scopus 로고    scopus 로고
    • Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response
    • Sokol CL, Chu NQ, Yu S, Nish SA, Laufer TM, Medzhitov R. Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response. Nat Immunol 2009;10:713-20.
    • (2009) Nat Immunol , vol.10 , pp. 713-720
    • Sokol, C.L.1    Chu, N.Q.2    Yu, S.3    Nish, S.A.4    Laufer, T.M.5    Medzhitov, R.6
  • 44
    • 67649227119 scopus 로고    scopus 로고
    • Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells
    • Yoshimoto T, Yasuda K, Tanaka H et al. Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells. Nat Immunol 2009;10:706-12.
    • (2009) Nat Immunol , vol.10 , pp. 706-712
    • Yoshimoto, T.1    Yasuda, K.2    Tanaka, H.3
  • 45
    • 58149257537 scopus 로고    scopus 로고
    • AnIL-1cytokine member, IL-33, induces human basophil activation via its ST2 receptor
    • Suzukawa M, Iikura M, Koketsu R et al. AnIL-1cytokine member, IL-33, induces human basophil activation via its ST2 receptor. J Immunol 2008;181:5981-9.
    • (2008) J Immunol , vol.181 , pp. 5981-5989
    • Suzukawa, M.1    Iikura, M.2    Koketsu, R.3
  • 46
    • 70349337464 scopus 로고    scopus 로고
    • IL-33Activates unprimed murine basophils directly in vitro and induces their in vivo expansion indirectly by promoting he-matopoietic growth factor production
    • Schneider E, Petit-Bertron AF, Bricard R et al. IL-33Activates unprimed murine basophils directly in vitro and induces their in vivo expansion indirectly by promoting he-matopoietic growth factor production. J Immunol 2009; 183:3591-7.
    • (2009) J Immunol , vol.183 , pp. 3591-3597
    • Schneider, E.1    Petit-Bertron, A.F.2    Bricard, R.3
  • 47
    • 70049104738 scopus 로고    scopus 로고
    • IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38 alpha-dependent pathway
    • Kroeger KM, Sullivan BM, Locksley RM. IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38 alpha-dependent pathway. JLeukocBiol 2009;86:769-78.
    • (2009) JLeukocBiol , vol.86 , pp. 769-778
    • Kroeger, K.M.1    Sullivan, B.M.2    Locksley, R.M.3
  • 49
    • 54949103126 scopus 로고    scopus 로고
    • Interleukin-33 enhances adhesion, CD11b expression and survival in human eosinophils
    • Suzukawa M, Koketsu R, Iikura M et al. Interleukin-33 enhances adhesion, CD11b expression and survival in human eosinophils. Lab Invest 2008;88:1245-53.
    • (2008) Lab Invest , vol.88 , pp. 1245-1253
    • Suzukawa, M.1    Koketsu, R.2    Iikura, M.3
  • 50
    • 65449146468 scopus 로고    scopus 로고
    • The pro-Th2 cy-tokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-gamma production
    • Bourgeois E, Van LP, Samson M et al. The pro-Th2 cy-tokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-gamma production. Eur J Immunol 2009;39:1046-55.
    • (2009) Eur J Immunol , vol.39 , pp. 1046-1055
    • Bourgeois, E.1    Van, L.P.2    Samson, M.3
  • 51
    • 73249141690 scopus 로고    scopus 로고
    • IL-33 promotes DC development in BM culture by triggering GM-CSF production
    • Mayuzumi N, Matsushima H, Takashima A. IL-33 promotes DC development in BM culture by triggering GM-CSF production. Eur J Immunol 2009;39:3331-42.
    • (2009) Eur J Immunol , vol.39 , pp. 3331-3342
    • Mayuzumi, N.1    Matsushima, H.2    Takashima, A.3
  • 53
    • 55149113944 scopus 로고    scopus 로고
    • Welcome to the neighborhood: Epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites
    • Saenz SA, Taylor BC, Artis D. Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites. Immunol Rev 2008;226:172-90.
    • (2008) Immunol Rev , vol.226 , pp. 172-190
    • Saenz, S.A.1    Taylor, B.C.2    Artis, D.3
  • 54
    • 0036301998 scopus 로고    scopus 로고
    • Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP
    • Soumelis V, Reche PA, Kanzler H et al. Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP. Nat Immunol 2002;3:673-80.
    • (2002) Nat Immunol , vol.3 , pp. 673-680
    • Soumelis, V.1    Reche, P.A.2    Kanzler, H.3
  • 55
    • 27744510433 scopus 로고    scopus 로고
    • TSLP-activated dendritic cells induce an inflammatory Thelper type 2 cell response through OX40 ligand
    • Ito T, Wang YH, Duramad O et al. TSLP-activated dendritic cells induce an inflammatory Thelper type 2 cell response through OX40 ligand. J Exp Med 2005;202:1213-23.
    • (2005) J Exp Med , vol.202 , pp. 1213-1223
    • Ito, T.1    Wang, Y.H.2    Duramad, O.3
  • 56
    • 34547820890 scopus 로고    scopus 로고
    • IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells
    • Wang YH, Angkasekwinai P, Lu N et al. IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells. J Exp Med 2007;204:1837-47.
    • (2007) J Exp Med , vol.204 , pp. 1837-1847
    • Wang, Y.H.1    Angkasekwinai, P.2    Lu, N.3
  • 57
    • 33846515975 scopus 로고    scopus 로고
    • Induction of IL-4 expression in CD4 (+) T cells by thymic stromal lymphopoietin
    • Omori M, Ziegler S. Induction of IL-4 expression in CD4 (+) T cells by thymic stromal lymphopoietin. J Immunol 2007;178:1396-404.
    • (2007) J Immunol , vol.178 , pp. 1396-13404
    • Omori, M.1    Ziegler, S.2
  • 58
    • 34447281733 scopus 로고    scopus 로고
    • Interleukin 25 promotes the initiation of proallergic type 2 responses
    • Angkasekwinai P, Park H, Wang YH et al. Interleukin 25 promotes the initiation of proallergic type 2 responses. J Exp Med 2007;204:1509-17.
    • (2007) J Exp Med , vol.204 , pp. 1509-1517
    • Angkasekwinai, P.1    Park, H.2    Wang, Y.H.3
  • 59
    • 0035336425 scopus 로고    scopus 로고
    • A novel pathway regulating lipopolysaccharide-induced shock by ST2/T1 via inhibition of Toll-like receptor 4 expression
    • Sweet MJ, Leung BP, Kang D et al. A novel pathway regulating lipopolysaccharide-induced shock by ST2/T1 via inhibition of Toll-like receptor 4 expression. J Immunol 2001;166:6633-9.
    • (2001) J Immunol , vol.166 , pp. 6633-6639
    • Sweet, M.J.1    Leung, B.P.2    Kang, D.3
  • 61
    • 0031587953 scopus 로고    scopus 로고
    • Expression of ST2, an interleukin-1 receptor homologue, is induced by proinflammatory stimuli
    • Kumar S, Tzimas MN, Griswold DE, Young PR. Expression of ST2, an interleukin-1 receptor homologue, is induced by proinflammatory stimuli. Biochem Biophys Res Commun 1997;235:474-8.
    • (1997) Biochem Biophys Res Commun , vol.235 , pp. 474-478
    • Kumar, S.1    Tzimas, M.N.2    Griswold, D.E.3    Young, P.R.4
  • 62
    • 0032190902 scopus 로고    scopus 로고
    • Divergent effects of LPS on expression of IL-1 receptor family members in mononuclear phagocytes in vitro and in vivo
    • Saccani S, Polentarutti N, Penton-Rol G, Sims JE, Man-tovani A. Divergent effects of LPS on expression of IL-1 receptor family members in mononuclear phagocytes in vitro and in vivo. Cytokine 1998;10:773-80.
    • (1998) Cytokine , vol.10 , pp. 773-780
    • Saccani, S.1    Polentarutti, N.2    Penton-Rol, G.3    Sims, J.E.4    Man-Tovani, A.5
  • 63
    • 70249083850 scopus 로고    scopus 로고
    • IL-33 enhances lipopolysaccharide-induced inflammatory cytokine production from mouse macrophages by regulating lipopolysaccharide receptor complex
    • Espinassous Q, Garcia-de-Paco E, Garcia-Verdugo I et al. IL-33 enhances lipopolysaccharide-induced inflammatory cytokine production from mouse macrophages by regulating lipopolysaccharide receptor complex. J Immunol 2009;183:1446-55.
    • (2009) J Immunol , vol.183 , pp. 1446-1455
    • Espinassous, Q.1    Garcia-de-Paco, E.2    Garcia-Verdugo, I.3
  • 64
    • 2642610290 scopus 로고    scopus 로고
    • Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells
    • Xu D, Chan WL, Leung BP et al. Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells. J Exp Med 1998;187:787-94.
    • (1998) J Exp Med , vol.187 , pp. 787-794
    • Xu, D.1    Chan, W.L.2    Leung, B.P.3
  • 65
    • 2942721674 scopus 로고    scopus 로고
    • ST2 is an inhibitor of inter-leukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance
    • Brint EK, Xu D, Liu H et al. ST2 is an inhibitor of inter-leukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nat Immunol 2004;5:373-9.
    • (2004) Nat Immunol , vol.5 , pp. 373-379
    • Brint, E.K.1    Xu, D.2    Liu, H.3
  • 66
    • 0031252311 scopus 로고    scopus 로고
    • Phenotypic and functional characterization of mice that lack the type I receptor for IL-1
    • Glaccum MB, Stocking KL, Charrier K et al. Phenotypic and functional characterization of mice that lack the type I receptor for IL-1. J Immunol 1997;159:3364-71.
    • (1997) J Immunol , vol.159 , pp. 3364-3371
    • Glaccum, M.B.1    Stocking, K.L.2    Charrier, K.3
  • 67
    • 0029768091 scopus 로고    scopus 로고
    • Functions of in-terleukin 1 receptor antagonist in gene knockout and overproducing mice
    • Hirsch E, Irikura VM, Paul SM, Hirsh D. Functions of in-terleukin 1 receptor antagonist in gene knockout and overproducing mice. Proc Natl Acad Sci U S A 1996;93: 11008-13.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 11008-11013
    • Hirsch, E.1    Irikura, V.M.2    Paul, S.M.3    Hirsh, D.4
  • 68
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon S. Alternative activation of macrophages. Nat Rev Immunol 2003;3:23-35.
    • (2003) Nat Rev Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 69
    • 0344393516 scopus 로고    scopus 로고
    • Regulation of macrophage activation
    • Ma J, Chen T, Mandelin J et al. Regulation of macrophage activation. Cell Mol Life Sci 2003;60:2334-46.
    • (2003) Cell Mol Life Sci , vol.60 , pp. 2334-2346
    • Ma, J.1    Chen, T.2    Mandelin, J.3
  • 71
    • 48349102876 scopus 로고    scopus 로고
    • Macrophage polarization in tumour progression
    • Sica A, Larghi P, Mancino A et al. Macrophage polarization in tumour progression. Semin Cancer Biol 2008;18: 349-55.
    • (2008) Semin Cancer Biol , vol.18 , pp. 349-355
    • Sica, A.1    Larghi, P.2    Mancino, A.3
  • 72
    • 75549085516 scopus 로고    scopus 로고
    • IL-33 amplifies the polarization of alternatively activated macro-phages that contribute to airway inflammation
    • Kurowska-Stolarska M, Stolarski B, Kewin P et al. IL-33 amplifies the polarization of alternatively activated macro-phages that contribute to airway inflammation. J Immunol 2009;183:6469-77.
    • (2009) J Immunol , vol.183 , pp. 6469-6477
    • Kurowska-Stolarska, M.1    Stolarski, B.2    Kewin, P.3
  • 73
    • 59449093130 scopus 로고    scopus 로고
    • CD34+ he-mopoietic progenitor cells are potent effectors of allergic inflammation
    • Allakhverdi Z, Comeau MR, Smith DE et al. CD34+ he-mopoietic progenitor cells are potent effectors of allergic inflammation. J Allergy Clin Immunol 2009;123:472-8.
    • (2009) J Allerg yClin Immunol , vol.123 , pp. 472-478
    • Allakhverdi, Z.1    Comeau, M.R.2    Smith, D.E.3
  • 74
    • 75749122181 scopus 로고    scopus 로고
    • Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Scalymphoid cells
    • Moro K, Yamada T, Tanabe M et al. Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Scalymphoid cells. Nature 2010;463:540-4.
    • (2010) Nature , vol.463 , pp. 540-544
    • Moro, K.1    Yamada, T.2    Tanabe, M.3
  • 75
    • 33845951211 scopus 로고    scopus 로고
    • DAMPs, PAMPs alarmins: All we need to know about danger
    • Bianchi ME. DAMPs, PAMPs alarmins: all we need to know about danger. J Leukoc Biol 2007;81:1-5.
    • (2007) J Leukoc Biol , vol.81 , pp. 1-5
    • Bianchi, M.E.1
  • 76
    • 17144376810 scopus 로고    scopus 로고
    • High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
    • Lotze MT, Tracey KJ. High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat Rev Immunol 2005;5:331-42.
    • (2005) Nat Rev Immunol , vol.5 , pp. 331-342
    • Lotze, M.T.1    Tracey, K.J.2
  • 77
    • 68249137289 scopus 로고    scopus 로고
    • Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases
    • Luthi AU, Cullen SP, McNeela EA et al. Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases. Immunity 2009;31:84-98.
    • (2009) Immunity , vol.31 , pp. 84-98
    • Luthi, A.U.1    Cullen, S.P.2    McNeela, E.A.3
  • 78
    • 67049158193 scopus 로고    scopus 로고
    • The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1
    • Cayrol C, Girard JP. The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1. Proc Natl Acad Sci U SA 2009;106:9021-6.
    • (2009) Proc Natl Acad Sci U SA , vol.106 , pp. 9021-9026
    • Cayrol, C.1    Girard, J.P.2
  • 79
    • 67651053209 scopus 로고    scopus 로고
    • Interleukin-33 is biologically active independently of caspase-1 cleavage
    • Talabot-Ayer D, Lamacchia C, Gabay C, Palmer G. Interleukin-33 is biologically active independently of caspase-1 cleavage. J Biol Chem 2009;284:19420-6.
    • (2009) J Biol Chem , vol.284 , pp. 19420-19426
    • Talabot-Ayer, D.1    Lamacchia, C.2    Gabay, C.3    Palmer, G.4
  • 80
    • 4844231880 scopus 로고    scopus 로고
    • Re-examination of the immunosup-pressive mechanisms mediating non-cure of Leishmania infection in mice
    • Sacks D, Anderson C. Re-examination of the immunosup-pressive mechanisms mediating non-cure of Leishmania infection in mice. Immunol Rev 2004;201:225-38.
    • (2004) Immunol Rev , vol.201 , pp. 225-238
    • Sacks, D.1    Anderson, C.2
  • 81
    • 0036740237 scopus 로고    scopus 로고
    • Organ-specific distribution of CD4+ T1/ST2+ Th2 cells in Leishmania major infection
    • Kropf P, Bickle Q, Herath S, Klemenz R, Muller I. Organ-specific distribution of CD4+ T1/ST2+ Th2 cells in Leishmania major infection. Eur J Immunol 2002;32:2450-9.
    • (2002) Eur J Immunol , vol.32 , pp. 2450-2459
    • Kropf, P.1    Bickle, Q.2    Herath, S.3    Klemenz, R.4    Muller, I.5
  • 82
    • 4844227879 scopus 로고    scopus 로고
    • Turning it on and off: Regulation of dendritic cell function in Toxoplasma gondii infection
    • Aliberti J, Jankovic D, Sher A. Turning it on and off: regulation of dendritic cell function in Toxoplasma gondii infection. Immunol Rev 2004;201:26-34.
    • (2004) Immunol Rev , vol.201 , pp. 26-34
    • Aliberti, J.1    Jankovic, D.2    Sher, A.3
  • 83
    • 75149148187 scopus 로고    scopus 로고
    • IL-33 receptor (T1 /ST2) signalling is necessary to prevent the development of encephalitis in mice infected with Toxoplasma gondii
    • Jones LA, Roberts F, Nickdel MB et al. IL-33 receptor (T1 /ST2) signalling is necessary to prevent the development of encephalitis in mice infected with Toxoplasma gondii. Eur J Immunol 2010;40:426-36.
    • (2010) Eur J Immunol , vol.40 , pp. 426-436
    • Jones, L.A.1    Roberts, F.2    Nickdel, M.B.3
  • 84
    • 4844221210 scopus 로고    scopus 로고
    • Interleukin-4- and interleukin-13-mediated host protection against intestinal nematode parasites
    • Finkelman FD, Shea-Donohue T, Morris SC et al. Interleukin-4- and interleukin-13-mediated host protection against intestinal nematode parasites. Immunol Rev 2004; 201:139-55.
    • (2004) Immunol Rev , vol.201 , pp. 139-155
    • Finkelman, F.D.1    Shea-Donohue, T.2    Morris, S.C.3
  • 85
    • 0033933919 scopus 로고    scopus 로고
    • T1-deficient and T1-Fc-transgenic mice develop a normal protective Th2-type immune response following infection with Nippostrongy-lus brasiliensis
    • Senn KA, McCoy KD, Maloy KJ et al. T1-deficient and T1-Fc-transgenic mice develop a normal protective Th2-type immune response following infection with Nippostrongy-lus brasiliensis. Eur J Immunol 2000;30:1929-38.
    • (2000) Eur J Immunol , vol.30 , pp. 1929-1938
    • Senn, K.A.1    McCoy, K.D.2    Maloy, K.J.3
  • 86
    • 4844229519 scopus 로고    scopus 로고
    • Th2 response polarization during infection with the helminth parasite Schistosoma mansoni
    • Pearce EJ, M Kane C, Sun J, J Taylor J, McKee AS, Cervi L. Th2 response polarization during infection with the helminth parasite Schistosoma mansoni. Immunol Rev 2004;201:117-26.
    • (2004) Immunol Rev , vol.201 , pp. 117-126
    • Pearce, E.J.1    Kane, M.C.2    Sun, J.3    Taylor, J.J.4    McKee, A.S.5    Cervi, L.6
  • 88
    • 7044245719 scopus 로고    scopus 로고
    • The Trichuris muris system: A paradigm of resistance and susceptibility to intestinal nema-tode infection
    • Cliffe LJ, Grencis RK. The Trichuris muris system: a paradigm of resistance and susceptibility to intestinal nema-tode infection. Adv Parasitol 2004;57:255-307.
    • (2004) Adv Parasitol , vol.57 , pp. 255-307
    • Cliffe, L.J.1    Grencis, R.K.2
  • 89
    • 42149179961 scopus 로고    scopus 로고
    • IL-33, a potent inducer of adaptive immunity to intestinal nematodes
    • Humphreys NE, Xu D, Hepworth MR, Liew FY, Grencis RK. IL-33, a potent inducer of adaptive immunity to intestinal nematodes. J Immunol 2008;180:2443-9.
    • (2008) J Immunol , vol.180 , pp. 2443-2449
    • Humphreys, N.E.1    Xu, D.2    Hepworth, M.R.3    Liew, F.Y.4    Grencis, R.K.5
  • 90
    • 35748951316 scopus 로고    scopus 로고
    • ST2 is essential for Th2 responsiveness and resistance to pseudomonas aeruginosa keratitis
    • Huang X, Du W, Barrett RP, Hazlett LD. ST2 is essential for Th2 responsiveness and resistance to pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci 2007;48: 4626-33.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 4626-4633
    • Huang, X.1    Du, W.2    Barrett, R.P.3    Hazlett, L.D.4
  • 91
    • 77949877897 scopus 로고    scopus 로고
    • IL-33shifts macrophage polarization, promoting resistance against Pseudomonas aeruginosa keratitis
    • Hazlett LD, McClellan SA, Barrett RP et al. IL-33shifts macrophage polarization, promoting resistance against Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci 2010;51:1524-32.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 1524-1532
    • Hazlett, L.D.1    McClellan, S.A.2    Barrett, R.P.3
  • 92
    • 67650932256 scopus 로고    scopus 로고
    • Cell-mediated immune responses in tuberculosis
    • Cooper AM. Cell-mediated immune responses in tuberculosis. Annu Rev Immunol 2009;27:393-422.
    • (2009) Annu Rev Immunol , vol.27 , pp. 393-422
    • Cooper, A.M.1
  • 93
    • 64549106883 scopus 로고    scopus 로고
    • ST2 deficient mice display a normal host defense against pulmonary infection with Mycobac-terium tuberculosis
    • Wieland CW, van der Windt GJ, Florquin S, McKenzie AN, van der Poll T. ST2 deficient mice display a normal host defense against pulmonary infection with Mycobac-terium tuberculosis. Microbes Infect 2009;11:524-30.
    • (2009) Microbes Infect , vol.11 , pp. 524-530
    • Wieland, C.W.1    van der Windt, G.J.2    Florquin, S.3    McKenzie, A.N.4    van der Poll, T.5
  • 94
    • 38449105679 scopus 로고    scopus 로고
    • Damping excessive inflammation and tissue damage in Mycobacterium tuberculosis infection by Toll IL-1 receptor 8/single Ig IL-1-related receptor, a negative regulator of IL-1/TLR signaling
    • Garlanda C, Di Liberto D, Vecchi A et al. Damping excessive inflammation and tissue damage in Mycobacterium tuberculosis infection by Toll IL-1 receptor 8/single Ig IL-1-related receptor, a negative regulator of IL-1/TLR signaling. J Immunol 2007;179:3119-25.
    • (2007) J Immunol , vol.179 , pp. 3119-3125
    • Garlanda, C.1    Di Liberto, D.2    Vecchi, A.3
  • 95
    • 68349099049 scopus 로고    scopus 로고
    • Soluble ST2 levels are associated with bleeding in patients with severe Leptospirosis
    • Wagenaar JF, Gasem MH, Goris MG et al. Soluble ST2 levels are associated with bleeding in patients with severe Leptospirosis. PLoS Negl Trop Dis 2009;3:e453.
    • (2009) PLoS Negl Trop Dis , vol.3
    • Wagenaar, J.F.1    Gasem, M.H.2    Goris, M.G.3
  • 96
    • 39149110584 scopus 로고    scopus 로고
    • Elevated levels of soluble ST2 protein in dengue virus infected patients
    • Becerra A, Warke RV, de Bosch N, Rothman AL, Bosch I. Elevated levels of soluble ST2 protein in dengue virus infected patients. Cytokine 2008;41:114-20.
    • (2008) Cytokine , vol.41 , pp. 114-120
    • Becerra, A.1    Warke, R.V.2    de Bosch, N.3    Rothman, A.L.4    Bosch, I.5
  • 98
    • 0035794272 scopus 로고    scopus 로고
    • Inhibition of T1/ST 2 during respiratory syncytial virus infection prevents T helper cell type 2 (Th2)- but not Th1-driven immunopa-thology
    • Walzl G, Matthews S, Kendall S et al. Inhibition of T1/ST 2 during respiratory syncytial virus infection prevents T helper cell type 2 (Th2)- but not Th1-driven immunopa-thology. J Exp Med 2001;193:785-92.
    • (2001) J Exp Med , vol.193 , pp. 785-792
    • Walzl, G.1    Matthews, S.2    Kendall, S.3
  • 99
    • 53149119525 scopus 로고    scopus 로고
    • Nuclear interleukin-33 is generally expressed in resting endothe-lium but rapidly lost upon angiogenic or proinflammatory activation
    • Kuchler AM, Pollheimer J, Balogh J et al. Nuclear interleukin-33 is generally expressed in resting endothe-lium but rapidly lost upon angiogenic or proinflammatory activation. Am J Pathol 2008;173:1229-42.
    • (2008) Am J Pathol , vol.173 , pp. 1229-1242
    • Kuchler, A.M.1    Pollheimer, J.2    Balogh, J.3
  • 100
    • 70449475108 scopus 로고    scopus 로고
    • IL-33 induces angiogene-sis and vascular permeability through ST2/TRAF6-mediated endothelial NO production
    • Choi YS, Choi HJ, Min JK et al. IL-33 induces angiogene-sis and vascular permeability through ST2/TRAF6-mediated endothelial NO production. Blood 2009;114: 3117-26.
    • (2009) Blood , vol.114 , pp. 3117-3126
    • Choi, Y.S.1    Choi, H.J.2    Min, J.K.3
  • 101
    • 0034081380 scopus 로고    scopus 로고
    • Construction of ELISA system to quantify human ST2 protein in sera of patients
    • Kuroiwa K, Li H, Tago K et al. Construction of ELISA system to quantify human ST2 protein in sera of patients. Hy-bridoma 2000;19:151-9.
    • (2000) Hy-bridoma , vol.19 , pp. 151-159
    • Kuroiwa, K.1    Li, H.2    Tago, K.3
  • 102
    • 0035880170 scopus 로고    scopus 로고
    • Elevated soluble ST2 protein levels in sera of patients with asthma with an acute exacerbation
    • Oshikawa K, Kuroiwa K, Tago K et al. Elevated soluble ST2 protein levels in sera of patients with asthma with an acute exacerbation. Am J Respir Crit Care Med 2001;164: 277-81.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 277-281
    • Oshikawa, K.1    Kuroiwa, K.2    Tago, K.3
  • 103
    • 75549084963 scopus 로고    scopus 로고
    • Increased expression of IL-33 in severe asthma: Evidence of expression by airway smooth muscle cells
    • Prefontaine D, Lajoie-Kadoch S, Foley S et al. Increased expression of IL-33 in severe asthma: evidence of expression by airway smooth muscle cells. J Immunol 2009;183: 5094-103.
    • (2009) J Immunol , vol.183 , pp. 5094-5103
    • Prefontaine, D.1    Lajoie-Kadoch, S.2    Foley, S.3
  • 104
    • 61349089164 scopus 로고    scopus 로고
    • Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
    • Gudbjartsson DF, Bjornsdottir US, Halapi E et al. Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Nat Genet 2009; 41:342-7.
    • (2009) Nat Genet , vol.41 , pp. 342-347
    • Gudbjartsson, D.F.1    Bjornsdottir, U.S.2    Halapi, E.3
  • 105
    • 50649089623 scopus 로고    scopus 로고
    • Association of IL1RL1, IL18R1, and IL18RAP gene cluster polymorphisms with asthma and atopy
    • Reijmerink NE, Postma DS, Bruinenberg M et al. Association of IL1RL1, IL18R1, and IL18RAP gene cluster polymorphisms with asthma and atopy. J Allergy Clin Immunol 2008;122:651-4. e8.
    • (2008) J Allergy Clin Immunol , vol.122
    • Reijmerink, N.E.1    Postma, D.S.2    Bruinenberg, M.3
  • 106
    • 60649092404 scopus 로고    scopus 로고
    • Investigations into the role of ST2 in acute asthma in children
    • Ali M, Zhang G, Thomas WR et al. Investigations into the role of ST2 in acute asthma in children. Tissue Antigens 2009;73:206-12.
    • (2009) Tissue Antigens , vol.73 , pp. 206-212
    • Ali, M.1    Zhang, G.2    Thomas, W.R.3
  • 107
    • 0036408831 scopus 로고    scopus 로고
    • Expression and function of the ST2 gene in a murine model of allergic airway inflammation
    • Oshikawa K, Yanagisawa K, Tominaga S, Sugiyama Y. Expression and function of the ST2 gene in a murine model of allergic airway inflammation. Clin Exp Allergy 2002;32: 1520-6.
    • (2002) Clin Exp Allergy , vol.32 , pp. 1520-1526
    • Oshikawa, K.1    Yanagisawa, K.2    Tominaga, S.3    Sugiyama, Y.4
  • 108
    • 34548825396 scopus 로고    scopus 로고
    • Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation
    • Hayakawa H, Hayakawa M, Kume A, Tominaga S. Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation. J Biol Chem 2007;282:26369-80.
    • (2007) J Biol Chem , vol.282 , pp. 26369-26380
    • Hayakawa, H.1    Hayakawa, M.2    Kume, A.3    Tominaga, S.4
  • 109
    • 34250303849 scopus 로고    scopus 로고
    • T1/ ST2 expression on Th2 cells negatively regulates allergic pulmonary inflammation
    • Mangan NE, Dasvarma A, McKenzie AN, Fallon PG. T1/ ST2 expression on Th2 cells negatively regulates allergic pulmonary inflammation. Eur J Immunol 2007;37:1302-12.
    • (2007) Eur J Immunol , vol.37 , pp. 1302-1312
    • Mangan, N.E.1    Dasvarma, A.2    McKenzie, A.N.3    Fallon, P.G.4
  • 110
    • 0035284903 scopus 로고    scopus 로고
    • Regulation and function ofT1/ST2 expression on CD4+T cells: Induction of type 2 cytokine production by T1/ST2 cross-linking
    • Meisel C, Bonhagen K, Lohning M et al. Regulation and function ofT1/ST2 expression on CD4+T cells: induction of type 2 cytokine production by T1/ST2 cross-linking. J Immunol 2001;166:3143-50.
    • (2001) J Immunol , vol.166 , pp. 3143-3150
    • Meisel, C.1    Bonhagen, K.2    Lohning, M.3
  • 111
    • 0033523665 scopus 로고    scopus 로고
    • Crucial role of the inter-leukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses
    • Coyle AJ, Lloyd C, Tian J et al. Crucial role of the inter-leukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses. J Exp Med 1999;190:895-902.
    • (1999) J Exp Med , vol.190 , pp. 895-902
    • Coyle, A.J.1    Lloyd, C.2    Tian, J.3
  • 112
    • 65549152797 scopus 로고    scopus 로고
    • Resolution of allergic inflammation and airway hyperreactivity is dependent upon disruption of the T1/ST2-IL-33 pathway
    • Kearley J, Buckland KF, Mathie SA, Lloyd CM. Resolution of allergic inflammation and airway hyperreactivity is dependent upon disruption of the T1/ST2-IL-33 pathway. Am J Respir Crit Care Med 2009;179:772-81.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 772-781
    • Kearley, J.1    Buckland, K.F.2    Mathie, S.A.3    Lloyd, C.M.4
  • 113
    • 67649207586 scopus 로고    scopus 로고
    • Anti-IL-33 antibody treatment inhibits airway inflammation in a murine model of allergic asthma
    • Liu X, Li M, Wu Y, Zhou Y, Zeng L, Huang T. Anti-IL-33 antibody treatment inhibits airway inflammation in a murine model of allergic asthma. Biochem Biophys Res Commun 2009;386:181-5.
    • (2009) Biochem Biophys Res Commun , vol.386 , pp. 181-185
    • Liu, X.1    Li, M.2    Wu, Y.3    Zhou, Y.4    Zeng, L.5    Huang, T.6
  • 114
    • 0030689729 scopus 로고    scopus 로고
    • Induction of airway mucus production By T helper 2 (Th2) cells: A critical role for interleukin 4 in cell recruitment but not mucus production
    • Cohn L, Homer RJ, Marinov A, Rankin J, Bottomly K. Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production. J Exp Med 1997;186:1737-47.
    • (1997) J Exp Med , vol.186 , pp. 1737-1747
    • Cohn, L.1    Homer, R.J.2    Marinov, A.3    Rankin, J.4    Bottomly, K.5
  • 115
    • 26444600821 scopus 로고    scopus 로고
    • Functional SNPs in the distal promoter of the ST2 gene are associated with atopic dermatitis
    • Shimizu M, Matsuda A, Yanagisawa K et al. Functional SNPs in the distal promoter of the ST2 gene are associated with atopic dermatitis. Hum Mol Genet 2005;14:2919-27.
    • (2005) Hum Mol Genet , vol.14 , pp. 2919-2927
    • Shimizu, M.1    Matsuda, A.2    Yanagisawa, K.3
  • 116
    • 56549130616 scopus 로고    scopus 로고
    • Association of serum interleukin-33 level and the interleukin-33 genetic variant with Japanese cedar pollinosis
    • Sakashita M, Yoshimoto T, Hirota T et al. Association of serum interleukin-33 level and the interleukin-33 genetic variant with Japanese cedar pollinosis. Clin Exp Allergy 2008;38:1875-81.
    • (2008) Clin Exp Allergy , vol.38 , pp. 1875-1881
    • Sakashita, M.1    Yoshimoto, T.2    Hirota, T.3
  • 117
    • 70349257814 scopus 로고    scopus 로고
    • Evidence of association of interleukin-1 receptor-like 1 gene polymorphisms with chronic rhinosinusitis
    • Castano R, Bosse Y, Endam LM, Desrosiers M. Evidence of association of interleukin-1 receptor-like 1 gene polymorphisms with chronic rhinosinusitis. Am J Rhinol Allergy 2009;23:377-84.
    • (2009) Am J Rhinol Allergy , vol.23 , pp. 377-384
    • Castano, R.1    Bosse, Y.2    Endam, L.M.3    Desrosiers, M.4
  • 118
    • 33748762295 scopus 로고    scopus 로고
    • Gene expression profiling of skin and draining lymph nodes of rats affected with cutaneous contact hy-persensitivity
    • Hartmann B, Staedtler F, Hartmann N, Meingassner J, Fi-rat H. Gene expression profiling of skin and draining lymph nodes of rats affected with cutaneous contact hy-persensitivity. Inflamm Res 2006;55:322-34.
    • (2006) Inflamm Res , vol.55 , pp. 322-334
    • Hartmann, B.1    Staedtler, F.2    Hartmann, N.3    Meingassner, J.4    Fi-Rat, H.5
  • 119
    • 70349572801 scopus 로고    scopus 로고
    • TheRoleof interleukin-33 in chronic allergic conjunctivitis
    • Matsuda A, Okayama Y, Terai N et al. TheRoleof interleukin-33 in chronic allergic conjunctivitis. Invest Ophthalmol Vis Sci 2009;50:4646-52.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 4646-4652
    • Matsuda, A.1    Okayama, Y.2    Terai, N.3
  • 120
    • 47249161332 scopus 로고    scopus 로고
    • Elevated soluble ST2 and cytokine levels in synovial fluids of patients with inflammatory synovitis
    • Fraser A, Moore M, Jongbloed S, Gracie A, McInnes IB. Elevated soluble ST2 and cytokine levels in synovial fluids of patients with inflammatory synovitis. Ann Rheum Dis 2006;65(Suppl 1):A10.
    • (2006) Ann Rheum Dis , vol.65 , Issue.SUPPL. 1
    • Fraser, A.1    Moore, M.2    Jongbloed, S.3    Gracie, A.4    McInnes, I.B.5
  • 121
    • 49449111630 scopus 로고    scopus 로고
    • IL-33 exacerbates antigen-induced arthritis by activating mast cells
    • Xu D, Jiang HR, Kewin P et al. IL-33 exacerbates antigen-induced arthritis by activating mast cells. Proc Natl Acad Sci U S A 2008;105:10913-8.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 10913-10918
    • Xu, D.1    Jiang, H.R.2    Kewin, P.3
  • 122
    • 61649117392 scopus 로고    scopus 로고
    • Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis
    • Palmer G, Talabot-Ayer D, Lamacchia C et al. Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis. Arthritis Rheum 2009;60:738-49.
    • (2009) Arthritis Rheum , vol.60 , pp. 738-749
    • Palmer, G.1    Talabot-Ayer, D.2    Lamacchia, C.3
  • 123
    • 73649098450 scopus 로고    scopus 로고
    • Increased levels of interleukin 33 in sera and synovial fluid from patients with active rheumatoid arthritis
    • Matsuyama Y, Okazaki H, Tamemoto H et al. Increased levels of interleukin 33 in sera and synovial fluid from patients with active rheumatoid arthritis. J Rheumatol 2010;37:18-25.
    • (2010) J Rheumatol , vol.37 , pp. 18-25
    • Matsuyama, Y.1    Okazaki, H.2    Tamemoto, H.3
  • 124
    • 2942702125 scopus 로고    scopus 로고
    • A novel therapy of murine collagen-induced arthritis with soluble T1/ST2
    • Leung BP, Xu D, Culshaw S, McInnes IB, Liew FY. A novel therapy of murine collagen-induced arthritis with soluble T1/ST2. J Immunol 2004;173:145-50.
    • (2004) J Immunol , vol.173 , pp. 145-150
    • Leung, B.P.1    Xu, D.2    Culshaw, S.3    McInnes, I.B.4    Liew, F.Y.5
  • 125
    • 34248216953 scopus 로고    scopus 로고
    • Rodent models of streptozotocin-induced diabetic nephropathy
    • Tesch GH, Allen TJ. Rodent models of streptozotocin-induced diabetic nephropathy. Nephrology (Carlton) 2007; 12:261-6.
    • (2007) Nephrology (Carlton) , vol.12 , pp. 261-266
    • Tesch, G.H.1    Allen, T.J.2
  • 126
    • 37549029242 scopus 로고    scopus 로고
    • The mechanisms of alloxan- and streptozotocin-induced diabetes
    • Lenzen S. The mechanisms of alloxan- and streptozotocin-induced diabetes. Diabetologia 2008;51:216-26.
    • (2008) Diabetologia , vol.51 , pp. 216-226
    • Lenzen, S.1
  • 128
    • 0033526068 scopus 로고    scopus 로고
    • In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha
    • Pakala SV, Chivetta M, Kelly CB, Katz JD. In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha. J Exp Med 1999;189:1053-62.
    • (1999) J Exp Med , vol.189 , pp. 1053-1062
    • Pakala, S.V.1    Chivetta, M.2    Kelly, C.B.3    Katz, J.D.4
  • 129
    • 70350749391 scopus 로고    scopus 로고
    • Regulatory T cells and ST2 signaling control diabetes induction with multiple low doses of streptozotocin
    • Zdravkovic N, Shahin A, Arsenijevic N, Lukic ML, Mensah-Brown EP. Regulatory T cells and ST2 signaling control diabetes induction with multiple low doses of streptozotocin. Mol Immunol 2009;47:28-36.
    • (2009) Mol Immunol , vol.47 , pp. 28-36
    • Zdravkovic, N.1    Shahin, A.2    Arsenijevic, N.3    Lukic, M.L.4    Mensah-Brown, E.P.5
  • 130
    • 39549100797 scopus 로고    scopus 로고
    • IL-33 reduces the development of atherosclerosis
    • Miller AM, Xu D, Asquith DL et al. IL-33 reduces the development of atherosclerosis. J Exp Med 2008;205:339-46.
    • (2008) J Exp Med , vol.205 , pp. 339-346
    • Miller, A.M.1    Xu, D.2    Asquith, D.L.3
  • 131
    • 0030823158 scopus 로고    scopus 로고
    • Effects of age, sex, and ethnicity on the association between apolipopro-tein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium
    • Farrer LA, Cupples LA, Haines JL et al. Effects of age, sex, and ethnicity on the association between apolipopro-tein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA 1997;278:1349-56.
    • (1997) JAMA , vol.278 , pp. 1349-1356
    • Farrer, L.A.1    Cupples, L.A.2    Haines, J.L.3
  • 132
    • 70350568168 scopus 로고    scopus 로고
    • Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease
    • Chapuis J, Hot D, Hansmannel F et al. Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. Mol Psychiatry 2009;14:1004-16.
    • (2009) Mol Psychiatry , vol.14 , pp. 1004-1016
    • Chapuis, J.1    Hot, D.2    Hansmannel, F.3
  • 134
    • 77953721901 scopus 로고    scopus 로고
    • Characterization of the novel ST2/IL-33 system in patients with inflammatory bowel disease
    • In press
    • Beltran CJ, Nunez LE, Diaz-Jimenez D et al. Characterization of the novel ST2/IL-33 system in patients with inflammatory bowel disease. Inflamm Bowel Dis 2010. In press.
    • (2010) Inflamm Bowel Dis
    • Beltran, C.J.1    Nunez, L.E.2    Diaz-Jimenez, D.3
  • 135
    • 0029918501 scopus 로고    scopus 로고
    • Dextran sulfate sodium (DSS) induced experimental colitis in immunodeficient mice: Effects in CD4(+)-cell depleted, athymic and NK-cell depleted SCID mice
    • Axelsson LG, Landstrom E, Goldschmidt TJ, Gronberg A, Bylund-Fellenius AC. Dextran sulfate sodium (DSS) induced experimental colitis in immunodeficient mice: effects in CD4(+)-cell depleted, athymic and NK-cell depleted SCID mice. Inflamm Res 1996;45:181-91.
    • (1996) Inflamm Res , vol.45 , pp. 181-191
    • Axelsson, L.G.1    Landstrom, E.2    Goldschmidt, T.J.3    Gronberg, A.4    Bylund-Fellenius, A.C.5
  • 136
    • 13944264346 scopus 로고    scopus 로고
    • SingledoseofOCHim-proves mucosal T helper type 1/T helper type 2 cytokine balance and prevents experimental colitis in the presence of valpha14 natural killer T cells in mice
    • Ueno Y, Tanaka S, Sumii M et al. SingledoseofOCHim-proves mucosal T helper type 1/T helper type 2 cytokine balance and prevents experimental colitis in the presence of valpha14 natural killer T cells in mice. Inflamm Bowel Dis 2005;11:35-41.
    • (2005) Inflamm Bowel Dis , vol.11 , pp. 35-41
    • Ueno, Y.1    Tanaka, S.2    Sumii, M.3
  • 137
    • 0029083607 scopus 로고
    • Lack of crucial role of mast cells in pathogenesis of experimental colitis in mice
    • Minocha A, Thomas C, Omar R. Lack of crucial role of mast cells in pathogenesis of experimental colitis in mice. Dig Dis Sci 1995;40:1757-62.
    • (1995) Dig Dis Sci , vol.40 , pp. 1757-1762
    • Minocha, A.1    Thomas, C.2    Omar, R.3
  • 138
    • 38649129512 scopus 로고    scopus 로고
    • Shiftto-wards pro-inflammatory intestinal bacteria aggravates acute murine colitis via Toll-like receptors 2 and 4
    • Heimesaat MM, Fischer A, Siegmund B et al. Shiftto-wards pro-inflammatory intestinal bacteria aggravates acute murine colitis via Toll-like receptors 2 and 4. PLoS One 2007;2:e662.
    • (2007) PLoS One , vol.2
    • Heimesaat, M.M.1    Fischer, A.2    Siegmund, B.3
  • 139
    • 34247175428 scopus 로고    scopus 로고
    • The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial ho-meostasis, inflammation, and tumorigenesis
    • Xiao H, Gulen MF, Qin J et al. The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial ho-meostasis, inflammation, and tumorigenesis. Immunity 2007;26:461-75.
    • (2007) Immunity , vol.26 , pp. 461-475
    • Xiao, H.1    Gulen, M.F.2    Qin, J.3
  • 140
    • 77949480323 scopus 로고    scopus 로고
    • TheIL-1-like cytokine IL-33 and its receptor ST2 are abnormally expressed in the affected skin and visceral organs of patients with systemic sclerosis
    • Manetti M, Ibba-Manneschi L, Liakouli V et al. TheIL-1-like cytokine IL-33 and its receptor ST2 are abnormally expressed in the affected skin and visceral organs of patients with systemic sclerosis. Ann Rheum Dis 2010;69: 598-605.
    • (2010) Ann Rheum Dis , vol.69 , pp. 598-605
    • Manetti, M.1    Ibba-Manneschi, L.2    Liakouli, V.3
  • 141
    • 77949311799 scopus 로고    scopus 로고
    • IL-33 Induces IL-13-Dependent Cutaneous Fibrosis
    • Rankin AL, Mumm JB, Murphy E et al. IL-33 Induces IL-13-Dependent Cutaneous Fibrosis. J Immunol 2010;184: 1526-35.
    • (2010) J Immunol , vol.184 , pp. 1526-1535
    • Rankin, A.L.1    Mumm, J.B.2    Murphy, E.3
  • 142
    • 0034816240 scopus 로고    scopus 로고
    • Identification of human ST2 protein in the sera of patients with autoimmune diseases
    • Kuroiwa K, Arai T, Okazaki H, Minota S, Tominaga S. Identification of human ST2 protein in the sera of patients with autoimmune diseases. Biochem Biophys Res Commun 2001;284:1104-8.
    • (2001) Biochem Biophys Res Commun , vol.284 , pp. 1104-1108
    • Kuroiwa, K.1    Arai, T.2    Okazaki, H.3    Minota, S.4    Tominaga, S.5
  • 143
    • 77950534152 scopus 로고    scopus 로고
    • Serum levels of IL-33 and soluble ST2 and their association with disease activity in systemic lupus erythematosus
    • Mok MY, Huang FP, Ip WK et al. Serum levels of IL-33 and soluble ST2 and their association with disease activity in systemic lupus erythematosus. Rheumatology(Oxford) 2010;49:520-7.
    • (2010) Rheumatology(Oxford) , vol.49 , pp. 520-527
    • Mok, M.Y.1    Huang, F.P.2    Ip, W.K.3
  • 144
    • 49249109576 scopus 로고    scopus 로고
    • Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens
    • Lech M, Kulkarni OP, Pfeiffer S et al. Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens. J Exp Med 2008;205:1879-88.
    • (2008) J Exp Med , vol.205 , pp. 1879-1888
    • Lech, M.1    Kulkarni, O.P.2    Pfeiffer, S.3
  • 146
    • 2442621252 scopus 로고    scopus 로고
    • Serum levels of the interleukin-1 receptor family member ST2 predict mortality and clinical outcome in acute myocardial infarction
    • Shimpo M, Morrow DA, Weinberg EO et al. Serum levels of the interleukin-1 receptor family member ST2 predict mortality and clinical outcome in acute myocardial infarction. Circulation 2004;109:2186-90.
    • (2004) Circulation , vol.109 , pp. 2186-2190
    • Shimpo, M.1    Morrow, D.A.2    Weinberg, E.O.3
  • 147
    • 57449089014 scopus 로고    scopus 로고
    • Nonmyocardial production of ST2 protein in human hypertrophy and failure is related to diastolic load
    • Bartunek J, Delrue L, Van Durme F et al. Nonmyocardial production of ST2 protein in human hypertrophy and failure is related to diastolic load. J Am Coll Cardiol 2008;52: 2166-74.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 2166-2174
    • Bartunek, J.1    Delrue, L.2    van Durme, F.3
  • 148
    • 34249882513 scopus 로고    scopus 로고
    • IL-33 and ST2 comprise a critical biome-chanically induced and cardioprotective signaling system
    • Sanada S, Hakuno D, Higgins LJ, Schreiter ER, McKenzie AN, Lee RT. IL-33 and ST2 comprise a critical biome-chanically induced and cardioprotective signaling system. J Clin Invest 2007; 117:1538-49.
    • (2007) J Clin Invest , vol.117 , pp. 1538-1549
    • Sanada, S.1    Hakuno, D.2    Higgins, L.J.3    Schreiter, E.R.4    McKenzie, A.N.5    Lee, R.T.6
  • 149
    • 77949264462 scopus 로고    scopus 로고
    • Interleukin-33 prevents apoptosis and improves survival after experimental myocardial infarction through ST2 signaling
    • Seki K, Sanada S, Kudinova AY et al. Interleukin-33 prevents apoptosis and improves survival after experimental myocardial infarction through ST2 signaling. Circ Heart Fail 2009;2:684-91.
    • (2009) Circ Heart Fail , vol.2 , pp. 684-691
    • Seki, K.1    Sanada, S.2    Kudinova, A.Y.3
  • 150
    • 77955142252 scopus 로고    scopus 로고
    • Interleukin-33 overexpression is associated with liver fibrosis in mice and humans
    • Jun 5
    • Marvie P, Lisbonne M, L'Helgoualc'h A et al. Interleukin-33 overexpression is associated with liver fibrosis in mice and humans. J Cell Mol Med. Epub 2009 Jun 5.
    • (2009) J Cell Mol Med. Epub
    • Marvie, P.1    Lisbonne, M.2    L'helgoualc'h, A.3
  • 152
    • 3342969395 scopus 로고    scopus 로고
    • Interleukin-18 induces mechanical hyperno-ciception in rats via endothelin acting on ETB receptors in a morphine-sensitive manner
    • Verri WA Jr, Schivo IR, Cunha TM, Liew FY, Ferreira SH, Cunha FQ. Interleukin-18 induces mechanical hyperno-ciception in rats via endothelin acting on ETB receptors in a morphine-sensitive manner. J Pharmacol Exp Ther 2004;310:710-7.
    • (2004) J Pharmacol Exp Ther , vol.310 , pp. 710-717
    • Verri Jr., W.A.1    Schivo, I.R.2    Cunha, T.M.3    Liew, F.Y.4    Ferreira, S.H.5    Cunha, F.Q.6
  • 153
    • 50149083292 scopus 로고    scopus 로고
    • IL-1beta signaling initiates inflammatory hypernociception
    • White FA, Jones KJ. IL-1beta signaling initiates inflammatory hypernociception. Brain Behav Immun 2008;22: 1014-5.
    • (2008) Brain Behav Immun , vol.22 , pp. 1014-1015
    • White, F.A.1    Jones, K.J.2
  • 154
    • 40649127225 scopus 로고    scopus 로고
    • IL-33mediates antigen-induced cutaneous and articular hyperno-ciception in mice
    • Verri WA Jr, Guerrero AT, Fukada SY et al. IL-33mediates antigen-induced cutaneous and articular hyperno-ciception in mice. Proc Natl Acad Sci U S A 2008;105: 2723-8.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 2723-2728
    • Verri Jr., W.A.1    Guerrero, A.T.2    Fukada, S.Y.3


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