Interleukin-1 beta and transforming growth factor-beta 3 cooperate to activate matrix metalloproteinase expression and invasiveness in A549 lung adenocarcinoma cells

Cancer Letters

Volumn 325, Issue 2, 2012, Pages 220-226

  Petrella, Brenda L ^a,b   Armstrong, David A ^b   Vincenti, Matthew P ^a,b  

^a DEPARTMENT OF VETERANS AFFAIRS   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

Carcinoma; Interleukin 1beta; Matrix metalloproteinases; Non small cell lung; Transforming growth factor beta

Indexed keywords

INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; MITOGEN ACTIVATED PROTEIN KINASE; STROMELYSIN; STROMELYSIN 2; TRANSFORMING GROWTH FACTOR BETA3;

ARTICLE; CANCER CELL CULTURE; CARCINOMA CELL; CELL INVASION; EPITHELIAL MESENCHYMAL TRANSITION; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; MMP 1 GENE; MMP 10 GENE; MMP 3 GENE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ADENOCARCINOMA; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, RENAL CELL; CELL LINE, TUMOR; COLLAGEN; DRUG COMBINATIONS; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; ENZYME INDUCTION; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERLEUKIN-1BETA; KIDNEY NEOPLASMS; LAMININ; LUNG NEOPLASMS; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 10; MATRIX METALLOPROTEINASE 3; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; PROTEIN KINASE INHIBITORS; PROTEOGLYCANS; TRANSFORMING GROWTH FACTOR BETA3;

EID: 84865642101     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2012.07.009     Document Type: Article

References (21)

1. Hooker R.L., Pompili M.F., Mark J.B. Surgical aspects of non-small cell lung carcinoma. Curr. Opin. Pulm. Med. 1996, 2:277-284.
2. Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
3. Dinarello C.A. Why not treat human cancer with interleukin-1 blockade?. Cancer Metastasis Rev. 2010, 29:317-329.
4. Elaraj D.M., Weinreich D.M., Varghese S., Puhlmann M., Hewitt S.M., Carroll N.M., Feldman E.D., Turner E.M., Alexander H.R. The role of interleukin 1 in growth and metastasis of human cancer xenografts. Clin. Cancer Res. 2006, 12:1088-1096.
5. Krelin Y., Voronov E., Dotan S., Elkabets M., Reich E., Fogel M., Huszar M., Iwakura Y., Segal S., Dinarello C.A., Apte R.N. Interleukin-1beta-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors. Cancer Res. 2007, 67:1062-1071.
6. Tian M., Neil J.R., Schiemann W.P. Transforming growth factor-beta and the hallmarks of cancer. Cell. Signal. 2011, 23:951-962.
7. Shi W., Heisterkamp N., Groffen J., Zhao J., Warburton D., Kaartinen V. TGF-beta3-null mutation does not abrogate fetal lung maturation in vivo by glucocorticoids. Am. J. Physiol. 1999, 277:L1205-1213.
8. Laverty H.G., Wakefield L.M., Occleston N.L., O'Kane S., Ferguson M.W. TGF-beta3 and cancer: a review. Cytokine Growth Factor Rev. 2009, 20:305-317.
9. Vincenti M., Brinckerhoff C. Signal transduction and cell-type specific regulation of matrix metalloproteinase gene expression: can MMPs be good for you?. J. Cell. Physiol. 2007, 213:355-364.
10. Chetty C., Rao J.S., Lakka S.S. Matrix metalloproteinase pharmacogenomics in non-small-cell lung carcinoma. Pharmacogenomics 2011, 12:535-546.
11. Huntington J.T., Shields J.M., Der C.J., Wyatt C.A., Benbow U., Slingluff C.L., Brinckerhoff C.E. Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling. J. Biol. Chem. 2004, 279:33168-33176.
12. Boire A., Covic L., Agarwal A., Jacques S., Sherifi S., Kuliopulos A. PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells. Cell 2005, 120:303-313.
13. Armstrong D., Phelps L., Vincenti M. CCAAT enhancer binding protein-regulates matrix metalloproteinase-1 expression in interleukin-1-stimulated A549 lung carcinoma cells. Mol. Cancer Res. 2009, 7:1517-1524.
14. Nagase H., Visse R., Murphy G. Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc. Res. 2006, 69:562-573.
15. Przybylo J.A., Radisky D.C. Matrix metalloproteinase-induced epithelial-mesenchymal transition: tumor progression at Snail's pace. Int. J. Biochem. Cell Biol. 2007, 39:1082-1088.
16. Lin C.C., Kuo C.T., Cheng C.Y., Wu C.Y., Lee C.W., Hsieh H.L., Lee I.T., Yang C.M. IL-1 beta promotes A549 cell migration via MAPKs/AP-1- and NF-kappaB-dependent matrix metalloproteinase-9 expression. Cell. Signal. 2009, 21:1652-1662.
17. Kasai H., Allen J.T., Mason R.M., Kamimura T., Zhang Z. TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT). Respir. Res. 2005, 6:56.
18. O'Callaghan D.S., O'Donnell D., O'Connell F., O'Byrne K.J. The role of inflammation in the pathogenesis of non-small cell lung cancer. J. Thorac. Oncol. 2010, 5:2024-2036.
19. Janmaat M.L., Rodriguez J.A., Gallegos-Ruiz M., Kruyt F.A., Giaccone G. Enhanced cytotoxicity induced by gefitinib and specific inhibitors of the Ras or phosphatidyl inositol-3 kinase pathways in non-small cell lung cancer cells. Int. J. Cancer 2006, 118:209-214.
20. Raymond L., Eck S., Mollmark J., Hays E., Tomek I., Kantor S., Elliott S., Vincenti M. Interleukin-1 beta induction of matrix metalloproteinase-1 transcription in chondrocytes requires ERK-dependent activation of CCAAT enhancer-binding protein-beta. J. Cell. Physiol. 2006, 207:683-688.
21. Barchowsky A., Frleta D., Vincenti M.P. Integration of the NF-kappaB and mitogen-activated protein kinase/AP-1 pathways at the collagenase-1 promoter: divergence of IL-1 and TNF-dependent signal transduction in rabbit primary synovial fibroblasts. Cytokine 2000, 12:1469-1479.