Production methods and stabilization strategies for polymer-based nanoparticles and microparticles for parenteral delivery of peptides and proteins

Expert Opinion on Drug Delivery

Volumn 12, Issue 8, 2015, Pages 1311-1331

  Teekamp, Naomi ^a   Duque, Luisa F ^b   Frijlink, Henderik W ^a   Hinrichs, Wouter Lj ^a   Olinga, Peter ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Formulation development; Microparticles; Nanoparticles; Peptide delivery; Peptide stability; Polymer; Protein delivery; Protein stability; Sustained release

Indexed keywords

MACROGOL; NANOPARTICLE; PEPTIDE; POLYMER; PROTEIN; EXCIPIENT; SOLVENT;

DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG STABILITY; ELECTROSPRAY; EMULSION; LAYER BY LAYER DEPOSITION; PARENTERAL DRUG ADMINISTRATION; PRECIPITATION; PROCEDURES; PROTEIN STABILITY; REVIEW; SOLVENT DISPLACEMENT; SOLVENT EVAPORATION; SPRAY DRYING; SUPERCRITICAL FLUID; CHEMISTRY; HUMAN; MEDICINAL CHEMISTRY;

CHEMISTRY, PHARMACEUTICAL; EXCIPIENTS; HUMANS; NANOPARTICLES; PEPTIDES; POLYMERS; PROTEINS; SOLVENTS;

EID: 84937207258     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2015.1003807     Document Type: Review

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