Chemical degradation of peptides and proteins in PLGA: A review of reactions and mechanisms

Journal of Pharmaceutical Sciences

Volumn 97, Issue 7, 2008, Pages 2395-2404

  Houchin, M L ^a,b   Topp, E M ^a  

^a UNIVERSITY OF KANSAS   (United States)

^b AMYLIN PHARMACEUTICALS INC   (United States)

Author keywords

Acylation; Deamidation; Hydrolysis; Peptide stability; PLGA

Indexed keywords

PEPTIDE; POLYGLACTIN;

ACYLATION; AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CONTROLLED DRUG RELEASE; DEAMINATION; ENANTIOMER; HYDROLYSIS; HYDROPHILICITY; PROTEIN DEGRADATION; SHORT SURVEY;

EID: 52449094115     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21176     Document Type: Short Survey

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