-
1
-
-
0025047522
-
New Methods of Drug Delivery
-
Langer, R. New Methods of Drug Delivery. Science 1990, 249, 1527-1533.
-
(1990)
Science
, vol.249
, pp. 1527-1533
-
-
Langer, R.1
-
2
-
-
0023695440
-
Vivo Release Profiles of Leuprolide Acetate from Microcapsules Prepared with Polylactic Acids or Coploy(Lactic/Glycolic) Acids and in Vivo Degradation of These Polymers
-
Ogawa, Y.; Okada, H.; Yamamoto, M.; Shimamoto, T. In Vivo Release Profiles of Leuprolide Acetate from Microcapsules Prepared with Polylactic Acids or Coploy(Lactic/Glycolic) Acids and in Vivo Degradation of These Polymers. Chem. Pharm. Bull. 1988, 36, 2576-2581.
-
(1988)
Chem. Pharm. Bull.
, vol.36
, pp. 2576-2581
-
-
Ogawa, Y.1
Okada, H.2
Yamamoto, M.3
Shimamoto, T.4
-
3
-
-
0023901210
-
A New Technique to Efficiently Entrap Leuprolide Acetate into Microcapsules of Polylactic Acid or Copoly(Lactic/Glycolic) Acid
-
Ogawa, Y.; Yamamoto, M.; Okada, H.; Yashiki, T.; Shimamoto, T. A New Technique to Efficiently Entrap Leuprolide Acetate into Microcapsules of Polylactic Acid or Copoly(Lactic/Glycolic) Acid. Chem. Pharm. Bull. 1988, 36, 1095-1103.
-
(1988)
Chem. Pharm. Bull.
, vol.36
, pp. 1095-1103
-
-
Ogawa, Y.1
Yamamoto, M.2
Okada, H.3
Yashiki, T.4
Shimamoto, T.5
-
4
-
-
0023943907
-
Controlled-Release of Leuprolide Acetate from Polylactic Acid or Copoly(Lactic/Glycolic) Acid Microcapsules: Influence of Molecular Weight and Copolymer Ratio of Polymer
-
Ogawa, Y.; Yamamoto, M.; Takada, S.; Okada, H.; Shimamoto, T. Controlled-Release of Leuprolide Acetate from Polylactic Acid or Copoly(Lactic/Glycolic) Acid Microcapsules: Influence of Molecular Weight and Copolymer Ratio of Polymer. Chem. Pharm. Bull. 1988, 36, 1502-1507.
-
(1988)
Chem. Pharm. Bull.
, vol.36
, pp. 1502-1507
-
-
Ogawa, Y.1
Yamamoto, M.2
Takada, S.3
Okada, H.4
Shimamoto, T.5
-
5
-
-
0038968339
-
-
Medical Economics Data: Montvale, NJ
-
Physicians' Desk Reference; Medical Economics Data: Montvale, NJ, 1996; pp 1061-1064, 2555-2562, 2858-2861.
-
(1996)
Physicians' Desk Reference
, pp. 1061-1064
-
-
-
6
-
-
8244250126
-
The Stability of Recombinant Human Growth Hormone in Poly(lactic-co-glycolic acid) (PLGA) Microspheres
-
Cleland, J. L.; Mac, A.; Boyd, B.; Yang, J.; Duenas, E. T.; Yeung, D.; Brooks, D.; Hsu, C.; Chu, H.; Mukku, V.; Jones, A. J. S. The Stability of Recombinant Human Growth Hormone in Poly(lactic-co-glycolic acid) (PLGA) Microspheres. Pharm. Res. 1997, 14, 420-425.
-
(1997)
Pharm. Res.
, vol.14
, pp. 420-425
-
-
Cleland, J.L.1
Mac, A.2
Boyd, B.3
Yang, J.4
Duenas, E.T.5
Yeung, D.6
Brooks, D.7
Hsu, C.8
Chu, H.9
Mukku, V.10
Jones, A.J.S.11
-
7
-
-
0029859532
-
Stable Formulations of Recombinant Human Growth Hormone and Interferon-γ for Microencapsulation in Biodegradable Microspheres
-
Cleland, J. L.; Jones, A. J. S. Stable Formulations of Recombinant Human Growth Hormone and Interferon-γ for Microencapsulation in Biodegradable Microspheres. Pharm. Res. 1996, 13, 1464-1475.
-
(1996)
Pharm. Res.
, vol.13
, pp. 1464-1475
-
-
Cleland, J.L.1
Jones, A.J.S.2
-
8
-
-
0031398790
-
Microencapsulation of rh-Erythropoietin, Using Biodegradable Poly(D,L-lactide-co-glycolide): Protein Stability and the Effects of Stabilizing Excipients
-
Morlock, M.; Koll, H.; Winter, G.; Kissel, T. Microencapsulation of rh-Erythropoietin, Using Biodegradable Poly(D,L-lactide-co-glycolide): Protein Stability and the Effects of Stabilizing Excipients. Eur. J. Pharm. Biopharm. 1997, 43, 29-36.
-
(1997)
Eur. J. Pharm. Biopharm.
, vol.43
, pp. 29-36
-
-
Morlock, M.1
Koll, H.2
Winter, G.3
Kissel, T.4
-
10
-
-
15844364250
-
A Month-Long Effect from a Single Injection of Microencapsulated Human Growth Hormone
-
Johnson, O. L.; Cleland, J. L.; Lee, H. J.; Charnis, M.; Duenas, E.; Jaworowicz, W.; Shepard, D.; Shahzamani, A.; Jones, A. J. S.; Putney, S. D. A Month-Long Effect from a Single Injection of Microencapsulated Human Growth Hormone. Nat. Med. 1996, 2, 795-799.
-
(1996)
Nat. Med.
, vol.2
, pp. 795-799
-
-
Johnson, O.L.1
Cleland, J.L.2
Lee, H.J.3
Charnis, M.4
Duenas, E.5
Jaworowicz, W.6
Shepard, D.7
Shahzamani, A.8
Jones, A.J.S.9
Putney, S.D.10
-
11
-
-
0027828184
-
Stability and Characterization of Human Growth Hormone
-
Yang, Y. J., Pearlman, R., Eds.; Plenum Press: New York
-
Pearlman, R.; Bewley, T. A. Stability and Characterization of Human Growth Hormone. In Stability and Characterization of Protein and Peptide Drugs: Case Histories; Yang, Y. J., Pearlman, R., Eds.; Plenum Press: New York, 1993; pp 1-58.
-
(1993)
Stability and Characterization of Protein and Peptide Drugs: Case Histories
, pp. 1-58
-
-
Pearlman, R.1
Bewley, T.A.2
-
12
-
-
8544246437
-
The Stabilization and Encapsulation of Human Growth Hormone into Biodegradable Microspheres
-
Johnson, O. L.; Jaworowicz, W.; Cleland, J. L.; Bailey, L.; Charnis, M.; Duenas, E.; Wu, C.; Shepard, D.; Magil, S.; Last, T.; Jones, A. J. S.; Putney, S. D. The Stabilization and Encapsulation of Human Growth Hormone into Biodegradable Microspheres. Pharm. Res. 1997, 14, 730-735.
-
(1997)
Pharm. Res.
, vol.14
, pp. 730-735
-
-
Johnson, O.L.1
Jaworowicz, W.2
Cleland, J.L.3
Bailey, L.4
Charnis, M.5
Duenas, E.6
Wu, C.7
Shepard, D.8
Magil, S.9
Last, T.10
Jones, A.J.S.11
Putney, S.D.12
-
13
-
-
0037491010
-
Draft Guideline on Impurities: Residual Solvents; Availability; Notice
-
International Conference on Harmonization; Draft Guideline on Impurities: Residual Solvents; Availability; Notice. Fed. Regist. 1997, 62 (May 2), 24302-24309.
-
(1997)
Fed. Regist.
, vol.62
, Issue.MAY 2
, pp. 24302-24309
-
-
-
14
-
-
0025823103
-
Dimerization of Human Growth Hormone by Zinc
-
Cunningham, B. C.; Mulkerrin, M. G.; Wells, J. A. Dimerization of Human Growth Hormone by Zinc. Science 1991, 253, 546-548.
-
(1991)
Science
, vol.253
, pp. 546-548
-
-
Cunningham, B.C.1
Mulkerrin, M.G.2
Wells, J.A.3
-
15
-
-
0017317645
-
Polymers for the Sustained Release of Proteins and Other Macromolecules
-
Langer, R.; Folkman, J. Polymers for the Sustained Release of Proteins and Other Macromolecules. Nature 1976, 263, 797-800.
-
(1976)
Nature
, vol.263
, pp. 797-800
-
-
Langer, R.1
Folkman, J.2
-
16
-
-
0021831170
-
An Explanation for the Controlled Release of Macromolecules from Polymers
-
Bawa, R.; Siegel, R.; Marasca, B.; Karel, M.; Langer, R. An Explanation for the Controlled Release of Macromolecules from Polymers. J. Controlled Release 1985, 1, 259-267.
-
(1985)
J. Controlled Release
, vol.1
, pp. 259-267
-
-
Bawa, R.1
Siegel, R.2
Marasca, B.3
Karel, M.4
Langer, R.5
-
17
-
-
0022043805
-
Polymers for the Controlled Release of Macromolecules: Effect of Molecular Weight of Ethylenevinyl Acetate Copolymer
-
Hsu, T.; Langer, R. Polymers for the Controlled Release of Macromolecules: Effect of Molecular Weight of Ethylenevinyl Acetate Copolymer. J. Biomed. Mater. Res. 1985, 19, 445-460.
-
(1985)
J. Biomed. Mater. Res.
, vol.19
, pp. 445-460
-
-
Hsu, T.1
Langer, R.2
-
18
-
-
0024555790
-
Transport Rates of Proteins in Porous Materials with Known Microgeometry
-
Saltzman, W. M.; Langer, R. Transport Rates of Proteins in Porous Materials with Known Microgeometry. Biophys. J. 1989, 55, 163-171.
-
(1989)
Biophys. J.
, vol.55
, pp. 163-171
-
-
Saltzman, W.M.1
Langer, R.2
-
19
-
-
0026545075
-
Poly(glycolic acid-co-DL-lactic acid): Diffusion or Degradation Controlled Drug Delivery
-
Shah, S. S.; Cha, Y.; Pitt, C. G. Poly(glycolic acid-co-DL-lactic acid): Diffusion or Degradation Controlled Drug Delivery. J. Controlled Release 1992, 18, 261-270.
-
(1992)
J. Controlled Release
, vol.18
, pp. 261-270
-
-
Shah, S.S.1
Cha, Y.2
Pitt, C.G.3
-
20
-
-
2642659664
-
-
unpublished data, 1997
-
Tracy, M. A. unpublished data, 1997.
-
-
-
Tracy, M.A.1
-
21
-
-
0029116812
-
Effects of Metal Salts on PLGA Hydrolysis
-
Zhang, Y.; Zale, S.; Alukonis, L.; Bernstein, H. Effects of Metal Salts on PLGA Hydrolysis. Proc. Int. Symp. Controlled Release Bioact. Mater. 1995, 22, 83-84.
-
(1995)
Proc. Int. Symp. Controlled Release Bioact. Mater.
, vol.22
, pp. 83-84
-
-
Zhang, Y.1
Zale, S.2
Alukonis, L.3
Bernstein, H.4
-
22
-
-
0031106860
-
Effects of Metal Salts on Poly(DL-lactide-co-glycolide) Polymer Hydrolysis
-
Zhang, Y.; Zale, S.; Sawyer, L.; Bernstein, H. Effects of Metal Salts on Poly(DL-lactide-co-glycolide) Polymer Hydrolysis. J. Biomed. Mater. Res. 1997, 34, 531-538.
-
(1997)
J. Biomed. Mater. Res.
, vol.34
, pp. 531-538
-
-
Zhang, Y.1
Zale, S.2
Sawyer, L.3
Bernstein, H.4
-
23
-
-
0029162435
-
Effects of PLGA End Groups on Degradation
-
Tracy, M. A.; Firouzabadian, L.; Zhang, Y. Effects of PLGA End Groups on Degradation. Proc. Int. Symp. Controlled Release Bioact. Mater. 1995, 22, 786-787.
-
(1995)
Proc. Int. Symp. Controlled Release Bioact. Mater.
, vol.22
, pp. 786-787
-
-
Tracy, M.A.1
Firouzabadian, L.2
Zhang, Y.3
-
24
-
-
0030061447
-
Sterilization, Toxicity, Biocompatibility and Clinical Applications of Polylactic Acid/Polyglycolic Acid Copolymers
-
Athanasiou, K. A.; Niederauer, G. G.; Agrawal, C. M. Sterilization, Toxicity, Biocompatibility and Clinical Applications of Polylactic Acid/Polyglycolic Acid Copolymers. Biomaterials 1996, 17, 93-102.
-
(1996)
Biomaterials
, vol.17
, pp. 93-102
-
-
Athanasiou, K.A.1
Niederauer, G.G.2
Agrawal, C.M.3
-
25
-
-
0022039832
-
J. Biodegradation of and Tissue Reaction to 50:50 Poly(DL-lactide-co-glycolide) Microcapsules
-
Visscher, G. E.; Robinson, R. L.; Maulding, H. V.; Fong, J. W.; Pearson, J. E.; Argentieri, G. J. Biodegradation of and Tissue Reaction to 50:50 Poly(DL-lactide-co-glycolide) Microcapsules. J. Biomed. Mater. Res. 1985, 19, 349-65.
-
(1985)
J. Biomed. Mater. Res.
, vol.19
, pp. 349-365
-
-
Visscher, G.E.1
Robinson, R.L.2
Maulding, H.V.3
Fong, J.W.4
Pearson, J.E.5
Argentieri, G.6
-
26
-
-
0023330464
-
Biodegradable Carriers for the Sustained Release of Polypeptides
-
Hutchinson, F. G.; Burr, B. J. A. Biodegradable Carriers for the Sustained Release of Polypeptides. Trends Biotechnol. 1987, 5, 102-106.
-
(1987)
Trends Biotechnol.
, vol.5
, pp. 102-106
-
-
Hutchinson, F.G.1
Burr, B.J.A.2
-
27
-
-
0030849860
-
Vivo and in Vitro Degradation of Poly(lactide-co-glycolide) Microspheres
-
Tracy, M. A.; Zhang, Y.; Verdon, S. L.; Dong, N.; Riley, M. G. I. In Vivo and In Vitro Degradation of Poly(lactide-co-glycolide) Microspheres. Proc. Int. Symp. Controlled Release Bioact. Mater. 1997, 24, 623-24.
-
(1997)
Proc. Int. Symp. Controlled Release Bioact. Mater.
, vol.24
, pp. 623-624
-
-
Tracy, M.A.1
Zhang, Y.2
Verdon, S.L.3
Dong, N.4
Riley, M.G.I.5
-
28
-
-
0006789567
-
Regulation of Insulin-like Growth Factor I Gene Expression by Growth Hormone
-
Mathews, L. S.; Norstedt, G.; Palmiter, R. D. Regulation of Insulin-like Growth Factor I Gene Expression by Growth Hormone. Proc. Natl. Acad. Sci. U.S.A. 1986, 83, 9343-9347.
-
(1986)
Proc. Natl. Acad. Sci. U.S.A.
, vol.83
, pp. 9343-9347
-
-
Mathews, L.S.1
Norstedt, G.2
Palmiter, R.D.3
-
29
-
-
0003265331
-
Vivo Characterization of Sustained-Release Formulations of Human Growth Hormone
-
Lee, H. J.; Riley, G.; Johnson, O. L.; Cleland, J. L.; Kim, N.; Charnis, M.; Bailey, L.; Duenas, E.; Shahzamani, A.; Marian, M.; Jones, A. J. S., Putney, S. D. In Vivo Characterization of Sustained-Release Formulations of Human Growth Hormone. J. Pharm. Exp. Ther. 1997, 281, 1431-1439.
-
(1997)
J. Pharm. Exp. Ther.
, vol.281
, pp. 1431-1439
-
-
Lee, H.J.1
Riley, G.2
Johnson, O.L.3
Cleland, J.L.4
Kim, N.5
Charnis, M.6
Bailey, L.7
Duenas, E.8
Shahzamani, A.9
Marian, M.10
Jones, A.J.S.11
Putney, S.D.12
-
30
-
-
0022474240
-
The Primary Structure of Monkey Pituitary Growth Hormone
-
Li, C. H.; Lahm, H. W.; Stein, S. The Primary Structure of Monkey Pituitary Growth Hormone. Arch. Biochem. Biophys. 1986, 245, 287-91.
-
(1986)
Arch. Biochem. Biophys.
, vol.245
, pp. 287-291
-
-
Li, C.H.1
Lahm, H.W.2
Stein, S.3
-
31
-
-
0343302750
-
Effects of Sustained Release Growth Hormone on Serum GH, IGF-I, and IGFBP-3 Concentrations in GH Deficient Adults
-
Vance, M. L.; Woodburn, C. J.; Putney, S. D.; Grous, J.; Lee, H. J.; Johnson, O. L. Effects of Sustained Release Growth Hormone on Serum GH, IGF-I, and IGFBP-3 Concentrations in GH Deficient Adults. Endocrinol. Metab. 1997, 4 (Suppl. A), 75.
-
(1997)
Endocrinol. Metab.
, vol.4
, Issue.SUPPL. A
, pp. 75
-
-
Vance, M.L.1
Woodburn, C.J.2
Putney, S.D.3
Grous, J.4
Lee, H.J.5
Johnson, O.L.6
-
32
-
-
0024370737
-
Molecular Forms of Serum Insulin-like Growth Factor (IGF)-Binding Proteins in Man: Relationships with Growth Hormone and IGFs and Physiological Significance
-
Hardouin, S.; Gourmelen, M.; Noguiez, P.; Seurin, D.; Roghani, M.; Le Bouc, Y.; Povoa, G.; Merimee, T. J.; Hossenlopp, P.; Binoux, M. Molecular Forms of Serum Insulin-like Growth Factor (IGF)-Binding Proteins in Man: Relationships with Growth Hormone and IGFs and Physiological Significance. J. Clin. Endocrinol. Metab. 1989, 69, 1291-1301.
-
(1989)
J. Clin. Endocrinol. Metab.
, vol.69
, pp. 1291-1301
-
-
Hardouin, S.1
Gourmelen, M.2
Noguiez, P.3
Seurin, D.4
Roghani, M.5
Le Bouc, Y.6
Povoa, G.7
Merimee, T.J.8
Hossenlopp, P.9
Binoux, M.10
-
33
-
-
0031917242
-
A Large Scale Process to Produce Microencapsulated Proteins
-
in press
-
Herbert, P.; Murphy, K.; Johnson, O. L.; Jaworowicz, W.; Tracy, M. A.; Cleland, J. L.; Putney, S. D. A Large Scale Process to Produce Microencapsulated Proteins. Pharm. Res., in press.
-
Pharm. Res.
-
-
Herbert, P.1
Murphy, K.2
Johnson, O.L.3
Jaworowicz, W.4
Tracy, M.A.5
Cleland, J.L.6
Putney, S.D.7
-
34
-
-
2642629970
-
Barrier Technology in a Biotechnology Research and Development Environment
-
Association pour les Produits Parentaux et Stériles: Congres de Bourdeaux 1996, October 16-18
-
Croll, D. B. Barrier Technology in a Biotechnology Research and Development Environment. In Compte Pendu des Communications; Association pour les Produits Parentaux et Stériles: Congres de Bourdeaux 1996, October 16-18, 1996; pp 111-114.
-
(1996)
Compte Pendu Des Communications
, pp. 111-114
-
-
Croll, D.B.1
|