Synthesis and physicochemical characterization of a novel amphiphilic polylactic acid-hyperbranched polyglycerol conjugate for protein delivery

Journal of Controlled Release

Volumn 140, Issue 2, 2009, Pages 141-147

  Gao, Xiujun ^a   Zhang, Xinge ^a   Wu, Zhongming ^b   Zhang, Xuejiao ^a   Wang, Zhen ^a   Li, Chaoxing ^a  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Amphiphilic copolymer; Biocompatibility; Biomacromolecule delivery; Hyperbranched polyglycerol; Protein

Indexed keywords

AMPHIPHILIC COPOLYMER; AMPHIPHILIC COPOLYMERS; AMPHIPHILICS; AQUEOUS SOLUTIONS; ASSOCIATION EFFICIENCY; BIOMACROMOLECULE DELIVERY; CELL VIABILITY; COPOLYMER COMPOSITIONS; CORE STRUCTURE; HYPERBRANCHED POLYGLYCEROL; LOADING CAPACITIES; ORIGINAL STRUCTURES; PHYSICO-CHEMICAL CHARACTERIZATION; POLY LACTIC ACID; PROTEIN DELIVERY; PROTEIN DELIVERY SYSTEMS; PROTEIN RELEASE;

ACIDS; BIOCOMPATIBILITY; BODY FLUIDS; CIRCULAR DICHROISM SPECTROSCOPY; COPOLYMERIZATION; DENDRIMERS; DICHROISM; NANOPARTICLES; PLASTIC PRODUCTS; SYNTHESIS (CHEMICAL);

POLYMER BLENDS;

AMPHOPHILE; BOVINE SERUM ALBUMIN; COPOLYMER; NANOPARTICLE; POLYLACTIC ACID HYPERBRANCHED POLYGLYCEROL CONJUGATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOCOMPATIBILITY; CELL VIABILITY; CHEMICAL COMPOSITION; CIRCULAR DICHROISM; CONJUGATE; DRUG DELIVERY SYSTEM; ENCAPSULATION; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN SECRETION; SYNTHESIS;

ANIMALS; CELL SURVIVAL; CHEMISTRY, PHARMACEUTICAL; CIRCULAR DICHROISM; DRUG CARRIERS; DRUG COMPOUNDING; GLYCEROL; KINETICS; LACTIC ACID; MICE; MOLECULAR STRUCTURE; NANOPARTICLES; NIH 3T3 CELLS; POLYMERS; PROTEIN CONFORMATION; PROTEIN STABILITY; SERUM ALBUMIN, BOVINE; SOLUBILITY;

EID: 70350622415     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.08.003     Document Type: Article

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