Reversible aggregation of lysozyme in a biodegradable amphiphilic multiblock copolymer

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 54, Issue 1, 2002, Pages 89-93

  Van de Weert, Marco ^a,c   Van Dijkhuizen Radersma, Riemke ^b   Bezemer, Jeroen M ^b   Hennink, Wim E ^a   Crommelin, Daan J A ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b IsoTis BV   (Netherlands)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Controlled drug delivery; Fourier transform infrared spectroscopy; Lysozyme; Poly(ethylene glycol terephthalate) poly(butylene terephthalate); Polymer film; Protein aggregation; Protein stability

Indexed keywords

COPOLYMER; LYSOZYME; METHANOL; POLY(ETHYLENE GLYCOL TEREPHTHALATE) POLY(BUTYLENE TEREPHTHALATE) COPOLYMER; UNCLASSIFIED DRUG; WATER OIL CREAM; BIOMATERIAL; POLY(1,4 BUTYLENE TEREPHTHALATE); POLY(1,4-BUTYLENE TEREPHTHALATE); POLYESTER; POLYETHYLENE TEREPHTHALATE; SURFACTANT;

ARTICLE; BIODEGRADABILITY; CONTROLLED DRUG RELEASE; DESICCATION; DRUG FORMULATION; DRUG RELEASE; EMULSION; ENCAPSULATION; EVAPORATION; FILM; IN VITRO STUDY; INFRARED SPECTROMETRY; METHODOLOGY; PROTEIN AGGREGATION; PROTEIN STABILITY; CHEMISTRY;

BIOCOMPATIBLE MATERIALS; MURAMIDASE; POLYESTERS; POLYETHYLENE TEREPHTHALATES; SURFACE-ACTIVE AGENTS;

EID: 0035985899     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(02)00017-6     Document Type: Article

References (12)

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5. Lysozyme distribution and conformation in a biodegradable polymer matrix as determined by FTIR techniques
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7. Measurement of protein using bichinchoninic acid
8. Protein structure by Fourier transform infrared spectroscopy: Second-derivative spectra
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