The effect of a water/organic solvent interface on the structural stability of lysozyme

Journal of Controlled Release

Volumn 68, Issue 3, 2000, Pages 351-359

  Van De Weert, Marco ^a   Hoechstetter, Julia ^a   Hennink, Wim E ^a   Crommelin, Daan J A ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Emulsification; Excipients; Lysozyme; Poly(lactic co glycolic acid); Protein stability

Indexed keywords

BOVINE SERUM ALBUMIN; DICHLOROMETHANE; GUANIDINE; LYSOZYME; POLYGLACTIN; POLYSORBATE 20; POLYSORBATE 80; POLYVINYL ALCOHOL; SUCROSE; WATER;

ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED DRUG RELEASE; DRUG SOLUBILITY; EMULSION; ENZYME ACTIVITY; ENZYME ISOLATION; ENZYME STABILITY; LIQUID LIQUID EXTRACTION; MICROENCAPSULATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; STRUCTURE ANALYSIS;

ANTI-INFECTIVE AGENTS; DRUG CARRIERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EMULSIONS; LACTIC ACID; METHYLENE CHLORIDE; MICROSPHERES; MURAMIDASE; POLYGLYCOLIC ACID; POLYMERS; PROTEIN DENATURATION; SOLVENTS; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; WATER;

EID: 0034601661     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(00)00277-7     Document Type: Article

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