Microcosmic mechanisms for protein incomplete release and stability of various amphiphilicmPEG-PLA microspheres

Langmuir

Volumn 28, Issue 39, 2012, Pages 13984-13992

  Wei, Yi ^a,b   Wang, Yu Xia ^a   Wang, Wei ^c   Ho, Sa V ^c   Qi, Feng ^a,b   Ma, Guang Hui ^a   Su, Zhi Guo ^a  

^a INSTITUTE OF PROCESS ENGINEERING   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFM; AMPHIPHILICS; ATOMIC FORCE MICROSCOPE (AFM); BIOMACROMOLECULES; BIOMEDICAL FIELDS; CONFOCAL LASER SCANNING MICROSCOPY; DOUBLE EMULSIONS; ENCAPSULATION EFFICIENCY; HYDROPHILIC POLYMERS; IN-VITRO; L-LACTIDE; MICROCOSMIC MECHANISM; MICROENVIRONMENTS; NARROW SIZE DISTRIBUTIONS; NEW EXPERIMENTAL METHOD; PH CHANGE; PH SENSITIVE; POTENTIAL APPLICATIONS; PREMIX MEMBRANE EMULSIFICATION; PROTEIN DRUGS; QUARTZ CRYSTAL MICROBALANCE WITH DISSIPATION; RECOMBINANT HUMAN GROWTH HORMONES; RELEASE RATE; SUSTAINED RELEASE; TISSUE REGENERATION;

ATOMIC FORCE MICROSCOPY; CONFOCAL MICROSCOPY; CONTACT ANGLE; DRUG DELIVERY; EMULSIFICATION; ENCAPSULATION; GLYCOLS; HYDROPHILICITY; MICROSPHERES; MOTION PICTURE EXPERTS GROUP STANDARDS; PROTEINS; TISSUE;

STABILITY;

HUMAN GROWTH HORMONE; LACTIC ACID; MACROGOL DERIVATIVE; MICROSPHERE; MONOMETHOXYPOLYETHYLENE GLYCOL; POLYLACTIC ACID; POLYMER; RECOMBINANT PROTEIN; SURFACTANT;

ARTICLE; CHEMISTRY; HUMAN; PARTICLE SIZE; SURFACE PROPERTY;

HUMAN GROWTH HORMONE; HUMANS; LACTIC ACID; MICROSPHERES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYMERS; RECOMBINANT PROTEINS; SURFACE PROPERTIES; SURFACE-ACTIVE AGENTS;

EID: 84867053415     PISSN: 07437463     EISSN: 15205827     Source Type: Journal    
DOI: 10.1021/la3017112     Document Type: Article

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