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Volumn 9, Issue JUN, 2015, Pages

Brain "fog," inflammation a nd obesity: Key aspects of neuropsychiatric disorders improved by luteolin

Author keywords

Brain; Cognition; Cytokines; Fog; Histamine hydroxytyrosol; Inflammation; Luteolin; Mast cells; Obesity; Olive fruit extract

Indexed keywords

CURCUMIN; FLAVONE DERIVATIVE; FLAVONOID; HISTAMINE; LUTEOLIN; OLIVE EXTRACT; PLANT EXTRACT; RESVERATROL; TETRAMETHOXYLUTEOLIN; UNCLASSIFIED DRUG;

EID: 84935075885     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2015.00225     Document Type: Article
Times cited : (118)

References (224)
  • 1
    • 77952868792 scopus 로고    scopus 로고
    • Mast cell-orchestrated immunity to pathogens
    • Abraham, S.N., St John, A.L. (2010). Mast cell-orchestrated immunity to pathogens . Nat. Rev. Immunol 10, 440-452.
    • (2010) Nat. Rev. Immunol , vol.10 , pp. 440-452
    • Abraham, S.N.1    St John, A.L.2
  • 4
    • 84893965054 scopus 로고    scopus 로고
    • Histamine in migraine and brain
    • Alstadhaug, K.B. (2014). Histamine in migraine and brain. Headache 54, 246-259.
    • (2014) Headache , vol.54 , pp. 246-259
    • Alstadhaug, K.B.1
  • 5
    • 0035887795 scopus 로고    scopus 로고
    • Histaminergic systems of the limbic complex on learning and motivation
    • Alvarez, E.O., Ruarte, M.B.and Banzan, A.M. (2001). Histaminergic systems of the limbic complex on learning and motivation. Behav. Brain Res. 124, 195-202.
    • (2001) Behav. Brain Res. , vol.124 , pp. 195-202
    • Alvarez, E.O.1    Ruarte, M.B.2    Banzan, A.M.3
  • 6
    • 84935115996 scopus 로고    scopus 로고
    • Alzheimer's Disease Facts and Figures. 2015.
    • Alzheimers Association. 2015 Alzheimer's Disease Facts and Figures. 2015.
    • (2015)
  • 7
    • 71749121785 scopus 로고    scopus 로고
    • Luteolin, a food-derived flavonoid, suppresses adipocyte-dependent activation of macrophages by inhibiting JNK activation
    • Ando, C., Takahashi, N., Hirai, S., Nishimura, K., Lin, S., Uemura, T.et al (2009). Luteolin, a food-derived flavonoid, suppresses adipocyte-dependent activation of macrophages by inhibiting JNK activation. FEBS Lett. 583, 3649-3654.
    • (2009) FEBS Lett , vol.583 , pp. 3649-3654
    • Ando, C.1    Takahashi, N.2    Hirai, S.3    Nishimura, K.4    Lin, S.5    Uemura, T.6
  • 9
    • 79953012546 scopus 로고    scopus 로고
    • Luteolin and thiosalicylate inhibit HgCl(2) and thimerosal-induced VEGF release from human mast cells
    • Asadi, S., Zhang, B., Weng, Z., Angelidou, A., Kempuraj, D., Alysandratos, K. D.et al (2010). Luteolin and thiosalicylate inhibit HgCl(2) and thimerosal-induced VEGF release from human mast cells. Int J Immunopathol. Pharmacol. 23, 1015-1020.
    • (2010) Int J Immunopathol. Pharmacol , vol.23 , pp. 1015-1020
    • Asadi, S.1    Zhang, B.2    Weng, Z.3    Angelidou, A.4    Kempuraj, D.5    Alysandratos, K.D.6
  • 10
    • 84924812512 scopus 로고    scopus 로고
    • Role of histaminergic system in blood-brain barrier dysfunction associated with neurological disorders
    • Banuelos-Cabrera, I., Valle-Dorado, M.G., Aldana, B.I., Orozco-Suarez, S.A.and Rocha, L. (2014). Role of histaminergic system in blood-brain barrier dysfunction associated with neurological disorders. Arch. Med Res. 45, 677-686.
    • (2014) Arch. Med Res. , vol.45 , pp. 677-686
    • Banuelos-Cabrera, I.1    Valle-Dorado, M.G.2    Aldana, B.I.3    Orozco-Suarez, S.A.4    Rocha, L.5
  • 12
    • 84868331824 scopus 로고    scopus 로고
    • The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes
    • Beumer, W., Gibney, S.M., Drexhage, R.C., Pont-Lezica, L., Doorduin, J., Klein, H.C.et al (2012). The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes. J Leukoc. Biol. 92, 959-975.
    • (2012) J Leukoc. Biol , vol.92 , pp. 959-975
    • Beumer, W.1    Gibney, S.M.2    Drexhage, R.C.3    Pont-Lezica, L.4    Doorduin, J.5    Klein, H.C.6
  • 13
    • 10344222887 scopus 로고    scopus 로고
    • The ins and outs of IgE-dependent mast-cell exocytosis
    • Blank, U., Rivera, J. (2004). The ins and outs of IgE-dependent mast-cell exocytosis. Trends Immunol 25, 266-273.
    • (2004) Trends Immunol , vol.25 , pp. 266-273
    • Blank, U.1    Rivera, J.2
  • 14
    • 0032788357 scopus 로고    scopus 로고
    • Biogenic amines in foods: histamine and food processing
    • Bodmer, S., Imark, C.and Kneubuhl, M. (1999). Biogenic amines in foods: histamine and food processing. Inflamm. Res. 48, 296-300.
    • (1999) Inflamm. Res. , vol.48 , pp. 296-300
    • Bodmer, S.1    Imark, C.2    Kneubuhl, M.3
  • 15
    • 84920583907 scopus 로고    scopus 로고
    • Antibacterial, antioxidant, anti-cholinesterase potential and flavonol glycosides of Biscutella raphanifolia (Brassicaceae)
    • Boudouda, H.B., Zeghib, A., Karioti, A., Bilia, A.R., Ozturk, M., Aouni, M.et al (2015). Antibacterial, antioxidant, anti-cholinesterase potential and flavonol glycosides of Biscutella raphanifolia (Brassicaceae). Pak. J Pharm. Sci. 28, 153-158.
    • (2015) Pak. J Pharm. Sci , vol.28 , pp. 153-158
    • Boudouda, H.B.1    Zeghib, A.2    Karioti, A.3    Bilia, A.R.4    Ozturk, M.5    Aouni, M.6
  • 17
    • 78650800249 scopus 로고    scopus 로고
    • Discovery of histamine H3 antagonists for the treatment of cognitive disorders and Alzheimer's disease
    • Brioni, J.D., Esbenshade, T.A., Garrison, T.R., Bitner, S.R.and Cowart, M.D. (2011). Discovery of histamine H3 antagonists for the treatment of cognitive disorders and Alzheimer's disease. J Pharmacol. Exp. Ther. 336, 38-46.
    • (2011) J Pharmacol. Exp. Ther. , vol.336 , pp. 38-46
    • Brioni, J.D.1    Esbenshade, T.A.2    Garrison, T.R.3    Bitner, S.R.4    Cowart, M.D.5
  • 18
    • 0031794962 scopus 로고    scopus 로고
    • Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro
    • Brown, J.E., Rice-Evans, C.A. (1998). Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro. Free Radic. Res. 29, 247-255.
    • (1998) Free Radic. Res. , vol.29 , pp. 247-255
    • Brown, J.E.1    Rice-Evans, C.A.2
  • 19
    • 84882869840 scopus 로고    scopus 로고
    • Antigen7 specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity
    • Bryniarski, K., Ptak, W., Jayakumar, A., Pullmann, K., Caplan, M.J., Chairoungdua, A.et al (2013). Antigen7 specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity. J Allergy Clin Immunol 132, 170-181.
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 170-181
    • Bryniarski, K.1    Ptak, W.2    Jayakumar, A.3    Pullmann, K.4    Caplan, M.J.5    Chairoungdua, A.6
  • 20
    • 84945488629 scopus 로고    scopus 로고
    • Adolescent-Onset Depression: Are Obesity and Inflammation Developmental Mechanisms or Outcomes?
    • in press.
    • Byrne, M.L., O'Brien-Simpson, N.M., Mitchell, S.A.and Allen, N.B. (2015). Adolescent-Onset Depression: Are Obesity and Inflammation Developmental Mechanisms or Outcomes? Child Psychiatry Hum. Dev. in press.
    • (2015) Child Psychiatry Hum. Dev.
    • Byrne, M.L.1    O'Brien-Simpson, N.M.2    Mitchell, S.A.3    Allen, N.B.4
  • 21
    • 20444366589 scopus 로고    scopus 로고
    • Human mast cells express corticotropin-releasing hormone (CRH) receptors and CRH leads to selective secretion of vascular endothelial growth factor
    • Cao, J., Papadopoulou, N., Kempuraj, D., Boucher, W.S., Sugimoto, K., Cetrulo, C.L.et al (2005). Human mast cells express corticotropin-releasing hormone (CRH) receptors and CRH leads to selective secretion of vascular endothelial growth factor. J Immunol 174, 7665-7675.
    • (2005) J Immunol , vol.174 , pp. 7665-7675
    • Cao, J.1    Papadopoulou, N.2    Kempuraj, D.3    Boucher, W.S.4    Sugimoto, K.5    Cetrulo, C.L.6
  • 22
    • 77952413047 scopus 로고    scopus 로고
    • Inflammasome signaling at the heart of central nervous system pathology
    • Chakraborty, S., Kaushik, D.K., Gupta, M.and Basu, A. (2010). Inflammasome signaling at the heart of central nervous system pathology. J Neurosci. Res 88, 1615-1631.
    • (2010) J Neurosci. Res , vol.88 , pp. 1615-1631
    • Chakraborty, S.1    Kaushik, D.K.2    Gupta, M.3    Basu, A.4
  • 23
    • 56049116002 scopus 로고    scopus 로고
    • Luteolin protects dopaminergic neurons from inflammation-induced injury through inhibition of microglial activation
    • Chen, H.Q., Jin, Z.Y., Wang, X.J., Xu, X.M., Deng, L.and Zhao, J.W. (2008). Luteolin protects dopaminergic neurons from inflammation-induced injury through inhibition of microglial activation. Neurosci. Lett. 448, 175-179.
    • (2008) Neurosci. Lett. , vol.448 , pp. 175-179
    • Chen, H.Q.1    Jin, Z.Y.2    Wang, X.J.3    Xu, X.M.4    Deng, L.5    Zhao, J.W.6
  • 24
    • 84896324163 scopus 로고    scopus 로고
    • Metabolism of flavonoids in human: a comprehensive review
    • Chen, Z., Zheng, S., Li, L.and Jiang, H. (2014). Metabolism of flavonoids in human: a comprehensive review. Curr Drug Metab 15, 48-61.
    • (2014) Curr Drug Metab , vol.15 , pp. 48-61
    • Chen, Z.1    Zheng, S.2    Li, L.3    Jiang, H.4
  • 26
    • 84860554747 scopus 로고    scopus 로고
    • New and emerging treatments for Alzheimer's disease
    • Corbett, A., Smith, J.and Ballard, C. (2012). New and emerging treatments for Alzheimer's disease. Expert. Rev. Neurother. 12, 535-543.
    • (2012) Expert. Rev. Neurother. , vol.12 , pp. 535-543
    • Corbett, A.1    Smith, J.2    Ballard, C.3
  • 27
    • 84865097262 scopus 로고    scopus 로고
    • Flavonoid basics: chemistry, sources, mechanisms of action, and safety
    • Corcoran, M.P., McKay, D.L.and Blumberg, J.B. (2012). Flavonoid basics: chemistry, sources, mechanisms of action, and safety. J Nutr Gerontol. Geriatr. 31, 176-189.
    • (2012) J Nutr Gerontol. Geriatr. , vol.31 , pp. 176-189
    • Corcoran, M.P.1    McKay, D.L.2    Blumberg, J.B.3
  • 30
    • 79951515436 scopus 로고    scopus 로고
    • Luteolin inhibits inflammatory response and improves insulin sensitivity in the endothelium
    • Deqiu, Z., Kang, L., Jiali, Y., Baolin, L.and Gaolin, L. (2011). Luteolin inhibits inflammatory response and improves insulin sensitivity in the endothelium. Biochimie 93, 506-512.
    • (2011) Biochimie , vol.93 , pp. 506-512
    • Deqiu, Z.1    Kang, L.2    Jiali, Y.3    Baolin, L.4    Gaolin, L.5
  • 31
    • 76749083375 scopus 로고    scopus 로고
    • Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype
    • Dirscherl, K., Karlstetter, M., Ebert, S., Kraus, D., Hlawatsch, J., Walczak, Y.et al (2010). Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype. J Neuroinflammation. 7, 3.
    • (2010) J Neuroinflammation , vol.7 , pp. 3
    • Dirscherl, K.1    Karlstetter, M.2    Ebert, S.3    Kraus, D.4    Hlawatsch, J.5    Walczak, Y.6
  • 32
  • 34
    • 79957800704 scopus 로고    scopus 로고
    • Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden
    • Drzezga, A., Becker, J.A., Van Dijk, K.R., Sreenivasan, A., Talukdar, T., Sullivan, C.et al (2011). Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden. Brain 134, 1635-1646.
    • (2011) Brain , vol.134 , pp. 1635-1646
    • Drzezga, A.1    Becker, J.A.2    Van Dijk, K.R.3    Sreenivasan, A.4    Talukdar, T.5    Sullivan, C.6
  • 35
    • 70350501195 scopus 로고    scopus 로고
    • Neurologic and neuropsychiatric syndrome features of mold and mycotoxin exposure
    • Empting, L.D. (2009). Neurologic and neuropsychiatric syndrome features of mold and mycotoxin exposure. Toxicol. Ind. Health 25, 577-581.
    • (2009) Toxicol. Ind. Health , vol.25 , pp. 577-581
    • Empting, L.D.1
  • 37
    • 84861417811 scopus 로고    scopus 로고
    • Effects of Pycnogenol on endothelial function in patients with stable coronary artery disease: a double-blind, randomized, placebo-controlled, cross-over study
    • Enseleit, F., Sudano, I., Periat, D., Winnik, S., Wolfrum, M., Flammer, A.J.et al (2012). Effects of Pycnogenol on endothelial function in patients with stable coronary artery disease: a double-blind, randomized, placebo-controlled, cross-over study. Eur Heart J 33, 1589-1597.
    • (2012) Eur Heart J , vol.33 , pp. 1589-1597
    • Enseleit, F.1    Sudano, I.2    Periat, D.3    Winnik, S.4    Wolfrum, M.5    Flammer, A.J.6
  • 38
    • 0036896468 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone (CRH) and brain mast cells regulate blood-brain-barrier permeability induced by acute stress
    • Esposito, P., Chandler, N., Kandere-Grzybowska, K., Basu, S., Jacobson, S., Connolly, R.et al (2002). Corticotropin-releasing hormone (CRH) and brain mast cells regulate blood-brain-barrier permeability induced by acute stress. J Pharmacol Exp Ther 303, 1061-1066.
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 1061-1066
    • Esposito, P.1    Chandler, N.2    Kandere-Grzybowska, K.3    Basu, S.4    Jacobson, S.5    Connolly, R.6
  • 39
    • 0035808531 scopus 로고    scopus 로고
    • Acute stress increases permeability of the blood-brain-barrier through activation of brain mast cells
    • Esposito, P., Gheorghe, D., Kandere, K., Pang, X., Conally, R., Jacobson, S.et al (2001). Acute stress increases permeability of the blood-brain-barrier through activation of brain mast cells. Brain Res 888, 117-127.
    • (2001) Brain Res , vol.888 , pp. 117-127
    • Esposito, P.1    Gheorghe, D.2    Kandere, K.3    Pang, X.4    Conally, R.5    Jacobson, S.6
  • 41
    • 84879369568 scopus 로고    scopus 로고
    • Identification through high-throughput screening of 4'-methoxyflavone and 3', 4'-dimethoxyflavone as novel neuroprotective inhibitors of parthanatos
    • Fatokun, A.A., Liu, J.O., Dawson, V.L.and Dawson, T.M. (2013). Identification through high-throughput screening of 4'-methoxyflavone and 3', 4'-dimethoxyflavone as novel neuroprotective inhibitors of parthanatos. Br J Pharmacol 169, 1263-1278.
    • (2013) Br J Pharmacol , vol.169 , pp. 1263-1278
    • Fatokun, A.A.1    Liu, J.O.2    Dawson, V.L.3    Dawson, T.M.4
  • 42
    • 84984588922 scopus 로고    scopus 로고
    • Structure activity relationship of flavonoids derived from medicinal plants in preventing methylmercury-induced mitochondrial dysfunction
    • Franco, J.L., Posser, T., Missau, F., Pizzolatti, M.G., Dos Santos, A.R., Souza, D. O.et al (2010). Structure activity relationship of flavonoids derived from medicinal plants in preventing methylmercury-induced mitochondrial dysfunction. Environ.Toxicol.Pharmacol 30, 272-278.
    • (2010) Environ. Toxicol. Pharmacol , vol.30 , pp. 272-278
    • Franco, J.L.1    Posser, T.2    Missau, F.3    Pizzolatti, M.G.4    Dos Santos, A.R.5    Souza, D.O.6
  • 43
    • 84908010443 scopus 로고    scopus 로고
    • Protective role of luteolin against cognitive dysfunction induced by chronic cerebral hypoperfusion in rats 1
    • Fu, X., Zhang, J., Guo, L., Xu, Y., Sun, L., Wang, S.et al (2014). Protective role of luteolin against cognitive dysfunction induced by chronic cerebral hypoperfusion in rats 1. Pharmacol. Biochem. Behav. 126, 122-130.
    • (2014) Pharmacol. Biochem. Behav , vol.126 , pp. 122-130
    • Fu, X.1    Zhang, J.2    Guo, L.3    Xu, Y.4    Sun, L.5    Wang, S.6
  • 44
    • 84922568635 scopus 로고    scopus 로고
    • Anti8 inflammatory activity of flavonoids in Nepalese propolis is attributed to inhibition of the IL-33 signaling pathway
    • Funakoshi-Tago, M., Okamoto, K., Izumi, R., Tago, K., Yanagisawa, K., Narukawa, Y.et al (2015). Anti8 inflammatory activity of flavonoids in Nepalese propolis is attributed to inhibition of the IL-33 signaling pathway. Int.Immunopharmacol. 25, 189-198.
    • (2015) Int.Immunopharmacol , vol.25 , pp. 189-198
    • Funakoshi-Tago, M.1    Okamoto, K.2    Izumi, R.3    Tago, K.4    Yanagisawa, K.5    Narukawa, Y.6
  • 45
    • 44349101991 scopus 로고    scopus 로고
    • Immunomodulatory mast cells: negative, as well as positive, regulators of immunity
    • Galli, S.J., Grimbaldeston, M.and Tsai, M. (2008). Immunomodulatory mast cells: negative, as well as positive, regulators of immunity. Nat Rev Immunol 8, 478-486.
    • (2008) Nat Rev Immunol , vol.8 , pp. 478-486
    • Galli, S.J.1    Grimbaldeston, M.2    Tsai, M.3
  • 46
    • 47949107183 scopus 로고    scopus 로고
    • The development of allergic inflammation
    • Galli, S.J., Tsai, M.and Piliponsky, A.M. (2008). The development of allergic inflammation. Nature 454, 445- 454.
    • (2008) Nature , vol.454 , pp. 445- 454
    • Galli, S.J.1    Tsai, M.2    Piliponsky, A.M.3
  • 47
  • 48
    • 4944254831 scopus 로고    scopus 로고
    • Cognitive impairment associated with toxigenic fungal exposure: a replication and extension of previous findings
    • Gordon, W.A., Cantor, J.B., Johanning, E., Charatz, H.J., Ashman, T.A., Breeze, J.L.et al (2004). Cognitive impairment associated with toxigenic fungal exposure: a replication and extension of previous findings. Appl. Neuropsychol. 11, 65-74.
    • (2004) Appl. Neuropsychol , vol.11 , pp. 65-74
    • Gordon, W.A.1    Cantor, J.B.2    Johanning, E.3    Charatz, H.J.4    Ashman, T.A.5    Breeze, J.L.6
  • 49
    • 84889249368 scopus 로고    scopus 로고
    • The use of flavonoids in central nervous system disorders
    • Grosso, C., Valentao, P., Ferreres, F.and Andrade, P.B. (2013). The use of flavonoids in central nervous system disorders. Curr Med Chem 20, 4697-4719.
    • (2013) Curr Med Chem , vol.20 , pp. 4697-4719
    • Grosso, C.1    Valentao, P.2    Ferreres, F.3    Andrade, P.B.4
  • 50
    • 84923384915 scopus 로고    scopus 로고
    • Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism
    • Gupta, S., Ellis, S.E., Ashar, F.N., Moes, A., Bader, J.S., Zhan, J.et al (2014). Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism. Nat. Commun. 5, 5748.
    • (2014) Nat. Commun , vol.5 , pp. 5748
    • Gupta, S.1    Ellis, S.E.2    Ashar, F.N.3    Moes, A.4    Bader, J.S.5    Zhan, J.6
  • 51
    • 50349091819 scopus 로고    scopus 로고
    • Histamine in the nervous system
    • Haas, H.L., Sergeeva, O.A.and Selbach, O. (2008). Histamine in the nervous system. Physiol Rev. 88, 1183- 1241.
    • (2008) Physiol Rev. , vol.88 , pp. 1183- 1241
    • Haas, H.L.1    Sergeeva, O.A.2    Selbach, O.3
  • 52
    • 77349090188 scopus 로고    scopus 로고
    • Physiology and cryosensitivity of coral endosymbiotic algae (Symbiodinium)
    • Hagedorn, M., Carter, V.L., Leong, J.C.and Kleinhans, F.W. (2010). Physiology and cryosensitivity of coral endosymbiotic algae (Symbiodinium). Cryobiology 60, 147-158.
    • (2010) Cryobiology , vol.60 , pp. 147-158
    • Hagedorn, M.1    Carter, V.L.2    Leong, J.C.3    Kleinhans, F.W.4
  • 53
    • 84881416732 scopus 로고    scopus 로고
    • Immunity, inflammation, and bipolar disorder: diagnostic and therapeutic implications
    • Hamdani, N., Doukhan, R., Kurtlucan, O., Tamouza, R.and Leboyer, M. (2013). Immunity, inflammation, and bipolar disorder: diagnostic and therapeutic implications. Curr. Psychiatry Rep. 15, 387.
    • (2013) Curr. Psychiatry Rep. , vol.15 , pp. 387
    • Hamdani, N.1    Doukhan, R.2    Kurtlucan, O.3    Tamouza, R.4    Leboyer, M.5
  • 54
    • 79954555973 scopus 로고    scopus 로고
    • Flavonoid modulation of GABA(A) receptors
    • Hanrahan, J.R., Chebib, M.and Johnston, G.A. (2011). Flavonoid modulation of GABA(A) receptors. Br J Pharmacol 163, 234-245.
    • (2011) Br J Pharmacol , vol.163 , pp. 234-245
    • Hanrahan, J.R.1    Chebib, M.2    Johnston, G.A.3
  • 55
    • 34548812546 scopus 로고    scopus 로고
    • A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties
    • Harwood, M., nielewska-Nikiel, B., Borzelleca, J.F., Flamm, G.W., Williams, G.M.and Lines, T.C. (2007). A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties. Food Chem. Toxicol. 45, 2179-2205.
    • (2007) Food Chem. Toxicol. , vol.45 , pp. 2179-2205
    • Harwood, M.1    nielewska-Nikiel, B.2    Borzelleca, J.F.3    Flamm, G.W.4    Williams, G.M.5    Lines, T.C.6
  • 57
    • 84873455519 scopus 로고    scopus 로고
    • Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease
    • Ho, L., Ferruzzi, M.G., Janle, E.M., Wang, J., Gong, B., Chen, T.Y.et al (2013). Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease. FASEB J 27, 769-781.
    • (2013) FASEB J , vol.27 , pp. 769-781
    • Ho, L.1    Ferruzzi, M.G.2    Janle, E.M.3    Wang, J.4    Gong, B.5    Chen, T.Y.6
  • 60
    • 0030775534 scopus 로고    scopus 로고
    • Absorption, metabolism and health effects of dietary man
    • Hollman, P.C., Katan, M.B. (1997). Absorption, metabolism and health effects of dietary man. Biomed. Pharmacother. 51, 305-310.
    • (1997) Biomed. Pharmacother. , vol.51 , pp. 305-310
    • Hollman, P.C.1    Katan, M.B.2
  • 62
    • 84935043640 scopus 로고    scopus 로고
    • Stress-induced interleukin- mast cell-dependent and more pronounced in Apolipoprotein E knockout mice.
    • Huang, M., Pang, X., Karalis, K.and Theoharides, T.C. (2003). Stress-induced interleukin- mast cell-dependent and more pronounced in Apolipoprotein E knockout mice. Cardiovasc. 249.
    • (2003) Cardiovasc , vol.249
    • Huang, M.1    Pang, X.2    Karalis, K.3    Theoharides, T.C.4
  • 64
    • 79952155950 scopus 로고    scopus 로고
    • Flavonoids and the CNS
    • Jager, A.K., Saaby, L. (2011). Flavonoids and the CNS. Molecules. 16, 1471-1485.
    • (2011) Molecules. , vol.16 , pp. 1471-1485
    • Jager, A.K.1    Saaby, L.2
  • 65
    • 77958133125 scopus 로고    scopus 로고
    • Luteolin inhibits microglia and alters hippocampal dependent spatial working memory in aged mice
    • Jang, S., Dilger, R.N.and Johnson, R.W. (2010). Luteolin inhibits microglia and alters hippocampal dependent spatial working memory in aged mice. J Nutr. 140, 1892-1898
    • (2010) J Nutr. , vol.140 , pp. 1892-1898
    • Jang, S.1    Dilger, R.N.2    Johnson, R.W.3
  • 66
    • 44949125522 scopus 로고    scopus 로고
    • Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1
    • Jang, S., Kelley, K.W.and Johnson, R.W. (2008). Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1. Proc Natl Acad Sci USA 105, 7534-7539.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 7534-7539
    • Jang, S.1    Kelley, K.W.2    Johnson, R.W.3
  • 67
    • 77249168715 scopus 로고    scopus 로고
    • A selective TrkB agonist with potent neurotrophic activities by 7, 8-dihydroxyflavone
    • Jang, S.W., Liu, X., Yepes, M., Shepherd, K.R., Miller, G.W., Liu, Y.et al (2010). A selective TrkB agonist with potent neurotrophic activities by 7, 8-dihydroxyflavone. Proc Natl Acad Sci USA 107, 2687-2692.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 2687-2692
    • Jang, S.W.1    Liu, X.2    Yepes, M.3    Shepherd, K.R.4    Miller, G.W.5    Liu, Y.6
  • 68
    • 84873279865 scopus 로고    scopus 로고
    • The role of the innate immune system in psychiatric disorders
    • Jones, K.A., Thomsen, C. (2013). The role of the innate immune system in psychiatric disorders. Mol. Cell Neurosci. 53, 52-62.
    • (2013) Mol. Cell Neurosci. , vol.53 , pp. 52-62
    • Jones, K.A.1    Thomsen, C.2
  • 70
    • 84935071697 scopus 로고    scopus 로고
    • Mast cells form antibody-dependent degranulatory synapse for dedicated secretion and defence
    • Joulia, R., Gaudenzio, N., Rodrigues, M., Lopez, J., Blanchard, N., Valitutti, S.et al (2015). Mast cells form antibody-dependent degranulatory synapse for dedicated secretion and defence. Nat. Commun. 6, 6174.
    • (2015) Nat. Commun , vol.6 , pp. 6174
    • Joulia, R.1    Gaudenzio, N.2    Rodrigues, M.3    Lopez, J.4    Blanchard, N.5    Valitutti, S.6
  • 71
    • 54549103514 scopus 로고    scopus 로고
    • New developments in mast cell biology
    • Kalesnikoff, J., Galli, S.J. (2008). New developments in mast cell biology. Nat. Immunol 9, 1215-1223.
    • (2008) Nat. Immunol , vol.9 , pp. 1215-1223
    • Kalesnikoff, J.1    Galli, S.J.2
  • 74
    • 0027310447 scopus 로고
    • Effect of histamine on memory retrieval in old rats
    • Kamei, C., Tasaka, K. (1993). Effect of histamine on memory retrieval in old rats. Biol. Pharm. Bull. 16, 128- 132.
    • (1993) Biol. Pharm. Bull. , vol.16 , pp. 128- 132
    • Kamei, C.1    Tasaka, K.2
  • 76
    • 79955759334 scopus 로고    scopus 로고
    • Luteolin inhibits cytokine expression in endotoxin/cytokine-stimulated microglia
    • Kao, T.K., Ou, Y.C., Lin, S.Y., Pan, H.C., Song, P.J., Raung, S.L.et al (2011). Luteolin inhibits cytokine expression in endotoxin/cytokine-stimulated microglia. J Nutr. Biochem. 22, 612-624.
    • (2011) J Nutr. Biochem , vol.22 , pp. 612-624
    • Kao, T.K.1    Ou, Y.C.2    Lin, S.Y.3    Pan, H.C.4    Song, P.J.5    Raung, S.L.6
  • 77
    • 28844448258 scopus 로고    scopus 로고
    • Evaluation for safety of antioxidant chemopreventive agents
    • Kawanishi, S., Oikawa, S.and Murata, M. (2005). Evaluation for safety of antioxidant chemopreventive agents. Antioxid. Redox. Signal. 7, 1728-1739.
    • (2005) Antioxid. Redox. Signal. , vol.7 , pp. 1728-1739
    • Kawanishi, S.1    Oikawa, S.2    Murata, M.3
  • 78
    • 84928078901 scopus 로고    scopus 로고
    • Diagnostic and therapeutic potentials of exosomes in CNS diseases
    • Kawikova, I., Askenase, P.W. (2014). Diagnostic and therapeutic potentials of exosomes in CNS diseases. Brain Res.
    • (2014) Brain Res.
    • Kawikova, I.1    Askenase, P.W.2
  • 79
    • 23744474477 scopus 로고    scopus 로고
    • Flavonols inhibit proinflammatory mediator release, intracellular calcium ion levels and protein kinase theta phosphorylation in human mast cells
    • Kempuraj, D., Madhappan, B., Christodoulou, S., Boucher, W., Cao, J., Papadopoulou, N.et al (2005). Flavonols inhibit proinflammatory mediator release, intracellular calcium ion levels and protein kinase theta phosphorylation in human mast cells. Br J Pharmacol 145, 934-944.
    • (2005) Br J Pharmacol , vol.145 , pp. 934-944
    • Kempuraj, D.1    Madhappan, B.2    Christodoulou, S.3    Boucher, W.4    Cao, J.5    Papadopoulou, N.6
  • 80
    • 56749169211 scopus 로고    scopus 로고
    • Luteolin myelin basic protein-induced human mast cell activation and mast cell dependent stimulation of Jurkat cells
    • Kempuraj, D., Tagen, M., Iliopoulou, B.P., Clemons, A., Vasiadi, M., Boucher, W.et al (2008). Luteolin myelin basic protein-induced human mast cell activation and mast cell dependent stimulation of Jurkat cells. Br J Pharmacol 155, 1076-1084.
    • (2008) Br J Pharmacol , vol.155 , pp. 1076-1084
    • Kempuraj, D.1    Tagen, M.2    Iliopoulou, B.P.3    Clemons, A.4    Vasiadi, M.5    Boucher, W.6
  • 83
    • 70350475573 scopus 로고    scopus 로고
    • Neurobehavioral and pulmonary impairment in 105 adults with indoor exposure molds compared to 100 exposed to chemicals
    • Kilburn, K.H. (2009). Neurobehavioral and pulmonary impairment in 105 adults with indoor exposure molds compared to 100 exposed to chemicals. Toxicol. Ind. Health 25, 681-692.
    • (2009) Toxicol. Ind. Health , vol.25 , pp. 681-692
    • Kilburn, K.H.1
  • 85
    • 0034062416 scopus 로고    scopus 로고
    • Effects of luteolin, quercetin and baicalein on immunoglobulin E-mediated mediator release from human cultured mast cells
    • Kimata, M., Shichijo, M., Miura, T., Serizawa, I., Inagaki, N.and Nagai, H. (2000). Effects of luteolin, quercetin and baicalein on immunoglobulin E-mediated mediator release from human cultured mast cells. Clin Exp Allergy 30, 501-508.
    • (2000) Clin Exp Allergy , vol.30 , pp. 501-508
    • Kimata, M.1    Shichijo, M.2    Miura, T.3    Serizawa, I.4    Inagaki, N.5    Nagai, H.6
  • 86
    • 0029165365 scopus 로고
    • Infiltrates of activated mast cells at the site of coronary atheromatous erosion or rupture in myocardial infarction
    • Kovanen, P.T., Kaartinen, M.and Paavonen, T. (1995). Infiltrates of activated mast cells at the site of coronary atheromatous erosion or rupture in myocardial infarction. Circulation 92, 1084-1088.
    • (1995) Circulation , vol.92 , pp. 1084-1088
    • Kovanen, P.T.1    Kaartinen, M.2    Paavonen, T.3
  • 89
    • 0032917040 scopus 로고    scopus 로고
    • Association between myocardial infarction and the mast cells in the adventitia of the infarct-related coronary artery
    • Laine, P., Kaartinen, M., Penttilä, A., Panula, P., Paavonen, T.and Kovanen, P.T. (1999). Association between myocardial infarction and the mast cells in the adventitia of the infarct-related coronary artery. Circulation 99, 361-369.
    • (1999) Circulation , vol.99 , pp. 361-369
    • Laine, P.1    Kaartinen, M.2    Penttilä, A.3    Panula, P.4    Paavonen, T.5    Kovanen, P.T.6
  • 90
    • 50649111341 scopus 로고    scopus 로고
    • Updated molecular knowledge about histamine biosynthesis by bacteria
    • Landete, J.M., De las, R.B., Marcobal, A.and Munoz, R. (2008). Updated molecular knowledge about histamine biosynthesis by bacteria. Crit Rev. Food Sci Nutr. 48, 697-714.
    • (2008) Crit Rev. Food Sci Nutr. , vol.48 , pp. 697-714
    • Landete, J.M.1    De las, R.B.2    Marcobal, A.3    Munoz, R.4
  • 91
    • 0029907276 scopus 로고    scopus 로고
    • The indoor microfungus Trichoderma viride potentiates histamine release from human bronchoalveolar cells
    • Larsen, F.O., Clementsen, P., Hansen, M., Maltbaek, N., Gravesen, S., Skov, P.S.et al (1996). The indoor microfungus Trichoderma viride potentiates histamine release from human bronchoalveolar cells. APMIS 104, 673-679.
    • (1996) APMIS , vol.104 , pp. 673-679
    • Larsen, F.O.1    Clementsen, P.2    Hansen, M.3    Maltbaek, N.4    Gravesen, S.5    Skov, P.S.6
  • 92
    • 84905754892 scopus 로고    scopus 로고
    • Editorial: 'brain fog' and coeliac disease - evidence for its existence
    • Lebwohl, B., Ludvigsson, J.F. (2014). Editorial: 'brain fog' and coeliac disease - evidence for its existence. Aliment. Pharmacol Ther 40, 565.
    • (2014) Aliment. Pharmacol Ther , vol.40 , pp. 565
    • Lebwohl, B.1    Ludvigsson, J.F.2
  • 93
    • 67651160771 scopus 로고    scopus 로고
    • Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau
    • Li, W., Sperry, J.B., Crowe, A., Trojanowski, J.Q., Smith, A.B., IIIand Lee, V.M. (2009). Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau. J Neurochem. 110, 1339-1351.
    • (2009) J Neurochem. , vol.110 , pp. 1339-1351
    • Li, W.1    Sperry, J.B.2    Crowe, A.3    Trojanowski, J.Q.4    Smith, A.B.5    Lee, V.M.6
  • 95
    • 0037022910 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis
    • Libby, P., Ridker, P.M.and Maseri, A. (2002). Inflammation and atherosclerosis. Circulation 105, 1135- 1143.
    • (2002) Circulation , vol.105 , pp. 1135- 1143
    • Libby, P.1    Ridker, P.M.2    Maseri, A.3
  • 96
    • 84902847956 scopus 로고    scopus 로고
    • Cognitive impairment in coeliac disease improves on a gluten-free diet and correlates with histological and serological indices of disease severity
    • Lichtwark, I.T., Newnham, E.D., Robinson, S.R., Shepherd, S.J., Hosking, P., Gibson, P.R.et al (2014). Cognitive impairment in coeliac disease improves on a gluten-free diet and correlates with histological and serological indices of disease severity. Aliment. Pharmacol Ther 40, 160-170.
    • (2014) Aliment. Pharmacol Ther , vol.40 , pp. 160-170
    • Lichtwark, I.T.1    Newnham, E.D.2    Robinson, S.R.3    Shepherd, S.J.4    Hosking, P.5    Gibson, P.R.6
  • 97
    • 79961151333 scopus 로고    scopus 로고
    • Luteolin inhibits the release of glutamate in rat cerebrocortical nerve terminals
    • Lin, T.Y., Lu, C.W., Chang, C.C., Huang, S.K.and Wang, S.J. (2011). Luteolin inhibits the release of glutamate in rat cerebrocortical nerve terminals. J Agric. Food Chem. 59, 8458-8466.
    • (2011) J Agric. Food Chem. , vol.59 , pp. 8458-8466
    • Lin, T.Y.1    Lu, C.W.2    Chang, C.C.3    Huang, S.K.4    Wang, S.J.5
  • 98
    • 68049102040 scopus 로고    scopus 로고
    • The anti-amnesic effects of luteolin against amyloid beta(25-35) peptide-induced toxicity in mice involve the protection of neurovascular unit
    • Liu, R., Gao, M., Qiang, G.F., Zhang, T.T., Lan, X., Ying, J.et al (2009). The anti-amnesic effects of luteolin against amyloid beta(25-35) peptide-induced toxicity in mice involve the protection of neurovascular unit. Neuroscience 162, 1232-1243.
    • (2009) Neuroscience , vol.162 , pp. 1232-1243
    • Liu, R.1    Gao, M.2    Qiang, G.F.3    Zhang, T.T.4    Lan, X.5    Ying, J.6
  • 99
    • 84873380843 scopus 로고    scopus 로고
    • Quercetin protects against the Abeta(25-35)-induced amnesic injury: involvement of inactivation of rage-mediated pathway and conservation of the NVU
    • Liu, R., Zhang, T.T., Zhou, D., Bai, X.Y., Zhou, W.L., Huang, C.et al (2013). Quercetin protects against the Abeta(25-35)-induced amnesic injury: involvement of inactivation of rage-mediated pathway and conservation of the NVU. Neuropharmacology 67, 419-431.
    • (2013) Neuropharmacology , vol.67 , pp. 419-431
    • Liu, R.1    Zhang, T.T.2    Zhou, D.3    Bai, X.Y.4    Zhou, W.L.5    Huang, C.6
  • 100
    • 84898605594 scopus 로고    scopus 로고
    • Luteolin protects against high fat diet-induced cognitive deficits in obesity mice
    • Liu, Y., Fu, X., Lan, N., Li, S., Zhang, J., Wang, S.et al (2014). Luteolin protects against high fat diet-induced cognitive deficits in obesity mice. Behav. Brain Res. 267, 178-188.
    • (2014) Behav. Brain Res , vol.267 , pp. 178-188
    • Liu, Y.1    Fu, X.2    Lan, N.3    Li, S.4    Zhang, J.5    Wang, S.6
  • 101
    • 62749165351 scopus 로고    scopus 로고
    • Distribution and biological activities of the flavonoid luteolin
    • Lopez-Lazaro, M. (2009). Distribution and biological activities of the flavonoid luteolin. Mini. Rev Med Chem 9, 31-59.
    • (2009) Mini. Rev Med Chem , vol.9 , pp. 31-59
    • Lopez-Lazaro, M.1
  • 102
    • 34248324818 scopus 로고    scopus 로고
    • Histamine and histamine intolerance
    • Maintz, L., Novak, N. (2007). Histamine and histamine intolerance. Am. J Clin Nutr. 85, 1185-1196.
    • (2007) Am. J Clin Nutr , vol.85 , pp. 1185-1196
    • Maintz, L.1    Novak, N.2
  • 105
    • 84865811819 scopus 로고    scopus 로고
    • Do we know enough about the immune pathogenesis of acute coronary syndromes to improve clinical practice?
    • Matusik, P., Guzik, B., Weber, C.and Guzik, T.J. (2012). Do we know enough about the immune pathogenesis of acute coronary syndromes to improve clinical practice? Thromb Haemost. 108, 443-456.
    • (2012) Thromb Haemost , vol.108 , pp. 443-456
    • Matusik, P.1    Guzik, B.2    Weber, C.3    Guzik, T.J.4
  • 106
    • 84926526559 scopus 로고    scopus 로고
    • Mast cells promote blood brain barrier breakdown and neutrophil infiltration in a mouse model of focal cerebral ischemia
    • McKittrick, C.M., Lawrence, C.E.and Carswell, H.V. (2015). Mast cells promote blood brain barrier breakdown and neutrophil infiltration in a mouse model of focal cerebral ischemia. J Cereb. Blood Flow Metab 35, 638-647.
    • (2015) J Cereb. Blood Flow Metab , vol.35 , pp. 638-647
    • McKittrick, C.M.1    Lawrence, C.E.2    Carswell, H.V.3
  • 108
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease and cancer
    • Middleton, E.J., Kandaswami, C.and Theoharides, T.C. (2000). The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease and cancer. Pharmacol Rev 52, 673-751.
    • (2000) Pharmacol Rev , vol.52 , pp. 673-751
    • Middleton, E.J.1    Kandaswami, C.2    Theoharides, T.C.3
  • 109
    • 0023771913 scopus 로고
    • High affinity benzodiazepine receptors on rat peritoneal mast cells and RBL-1 cells: binding characteristics and effects on granule secretion
    • Miller, L.G., Lee-Parritz, A., Greenblatt, D.J.and Theoharides, T.C. (1988). High affinity benzodiazepine receptors on rat peritoneal mast cells and RBL-1 cells: binding characteristics and effects on granule secretion. Pharmacology 36, 52-60.
    • (1988) Pharmacology , vol.36 , pp. 52-60
    • Miller, L.G.1    Lee-Parritz, A.2    Greenblatt, D.J.3    Theoharides, T.C.4
  • 110
    • 78651307006 scopus 로고    scopus 로고
    • The neuroprotective effect of olive leaf extract is related to improved blood-brain barrier permeability and brain edema in rat with experimental focal cerebral ischemia
    • Mohagheghi, F., Bigdeli, M.R., Rasoulian, B., Hashemi, P.and Pour, M.R. (2011). The neuroprotective effect of olive leaf extract is related to improved blood-brain barrier permeability and brain edema in rat with experimental focal cerebral ischemia. Phytomedicine. 18, 170-175.
    • (2011) Phytomedicine. , vol.18 , pp. 170-175
    • Mohagheghi, F.1    Bigdeli, M.R.2    Rasoulian, B.3    Hashemi, P.4    Pour, M.R.5
  • 111
    • 77955866894 scopus 로고    scopus 로고
    • Dietary virgin olive oil reduces blood brain barrier permeability, brain edema, and brain injury in rats subjected to ischemia3 reperfusion
    • Mohagheghi, F., Bigdeli, M.R., Rasoulian, B., Zeinanloo, A.A.and Khoshbaten, A. (2010). Dietary virgin olive oil reduces blood brain barrier permeability, brain edema, and brain injury in rats subjected to ischemia3 reperfusion. ScientificWorldJournal. 10, 1180-1191.
    • (2010) ScientificWorldJournal. , vol.10 , pp. 1180-1191
    • Mohagheghi, F.1    Bigdeli, M.R.2    Rasoulian, B.3    Zeinanloo, A.A.4    Khoshbaten, A.5
  • 112
    • 84905851370 scopus 로고    scopus 로고
    • Rupatadine effectively prevents the histamine-induced up regulation of histamine H1R and bradykinin B2R receptor gene expression in the rat paw
    • Molyva, D., Kalokasidis, K., Poulios, C., Dedi, H., Karkavelas, G., Mirtsou, V.et al (2014). Rupatadine effectively prevents the histamine-induced up regulation of histamine H1R and bradykinin B2R receptor gene expression in the rat paw. Pharmacol Rep. 66, 952-955.
    • (2014) Pharmacol Rep , vol.66 , pp. 952-955
    • Molyva, D.1    Kalokasidis, K.2    Poulios, C.3    Dedi, H.4    Karkavelas, G.5    Mirtsou, V.6
  • 114
    • 84862683302 scopus 로고    scopus 로고
    • Evidence for cognitive impairment in mastocytosis: prevalence, features and correlations to depression
    • Moura, D.S., Sultan, S., Georgin-Lavialle, S., Barete, S., Lortholary, O., Gaillard, R.et al (2012). Evidence for cognitive impairment in mastocytosis: prevalence, features and correlations to depression. PLoS.ONE. 7, e39468.
    • (2012) PLoS.ONE , vol.7
    • Moura, D.S.1    Sultan, S.2    Georgin-Lavialle, S.3    Barete, S.4    Lortholary, O.5    Gaillard, R.6
  • 115
    • 53749093767 scopus 로고    scopus 로고
    • The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel 'alarmin'?
    • Moussion, C., Ortega, N.and Girard, J.P. (2008). The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel 'alarmin'? PLoS.ONE. 3, e3331.
    • (2008) PLoS.ONE. , vol.3
    • Moussion, C.1    Ortega, N.2    Girard, J.P.3
  • 116
    • 84255186294 scopus 로고    scopus 로고
    • A pilot study on the effect of short-term consumption of a polyphenol rich drink on biomarkers of coronary artery disease defined by urinary proteomics
    • Mullen, W., Gonzalez, J., Siwy, J., Franke, J., Sattar, N., Mullan, A.et al (2011). A pilot study on the effect of short-term consumption of a polyphenol rich drink on biomarkers of coronary artery disease defined by urinary proteomics. J Agric. Food Chem 59, 12850-12857.
    • (2011) J Agric. Food Chem , vol.59 , pp. 12850-12857
    • Mullen, W.1    Gonzalez, J.2    Siwy, J.3    Franke, J.4    Sattar, N.5    Mullan, A.6
  • 117
    • 84870298815 scopus 로고    scopus 로고
    • Cytokines in bipolar disorder: a systematic review and meta-analysis
    • Munkholm, K., Vinberg, M.and Vedel, K.L. (2013). Cytokines in bipolar disorder: a systematic review and meta-analysis. J Affect. Disord. 144, 16-27.
    • (2013) J Affect. Disord. , vol.144 , pp. 16-27
    • Munkholm, K.1    Vinberg, M.2    Vedel, K.L.3
  • 118
    • 34247401706 scopus 로고    scopus 로고
    • Mast cell-derived TNF can promote Th17 cell dependent neutrophil recruitment in ovalbumin-challenged OTII mice
    • Nakae, S., Suto, H., Berry, G.J.and Galli, S.J. (2007). Mast cell-derived TNF can promote Th17 cell dependent neutrophil recruitment in ovalbumin-challenged OTII mice. Blood 109, 3640-3648.
    • (2007) Blood , vol.109 , pp. 3640-3648
    • Nakae, S.1    Suto, H.2    Berry, G.J.3    Galli, S.J.4
  • 119
    • 32044471903 scopus 로고    scopus 로고
    • Mast cells enhance T cell activation: importance of mast cell costimulatory molecules and secreted TNF
    • Nakae, S., Suto, H., Iikura, M., Kakurai, M., Sedgwick, J.D., Tsai, M.et al (2006). Mast cells enhance T cell activation: importance of mast cell costimulatory molecules and secreted TNF. J Immunol 176, 2238-2248.
    • (2006) J Immunol , vol.176 , pp. 2238-2248
    • Nakae, S.1    Suto, H.2    Iikura, M.3    Kakurai, M.4    Sedgwick, J.D.5    Tsai, M.6
  • 120
    • 84926407132 scopus 로고    scopus 로고
    • The circadian clock functions as a potent regulator of allergic reaction
    • Nakao, A., Nakamura, Y.and Shibata, S. (2015). The circadian clock functions as a potent regulator of allergic reaction. Allergy 70, 467-473.
    • (2015) Allergy , vol.70 , pp. 467-473
    • Nakao, A.1    Nakamura, Y.2    Shibata, S.3
  • 121
  • 122
    • 84883796702 scopus 로고    scopus 로고
    • Caught in the thickness of brain fog: exploring the cognitive symptoms of Chronic Fatigue Syndrome
    • Ocon, A.J. (2013). Caught in the thickness of brain fog: exploring the cognitive symptoms of Chronic Fatigue Syndrome. Front Physiol 4, 63.
    • (2013) Front Physiol , vol.4 , pp. 63
    • Ocon, A.J.1
  • 123
    • 0035887839 scopus 로고    scopus 로고
    • Histamine H(3)-receptor antagonism improves memory retention and reverses the cognitive deficit induced by scopolamine in a two-trial place recognition task
    • Orsetti, M., Ghi, P.and Di, C.G. (2001). Histamine H(3)-receptor antagonism improves memory retention and reverses the cognitive deficit induced by scopolamine in a two-trial place recognition task. Behav. Brain Res. 124, 235-242.
    • (2001) Behav. Brain Res. , vol.124 , pp. 235-242
    • Orsetti, M.1    Ghi, P.2    Di, C.G.3
  • 126
    • 30644461549 scopus 로고    scopus 로고
    • Immunity, neuroglia and neuroinflammation in autism
    • Pardo, C.A., Vargas, D.L.and Zimmerman, A.W. (2005). Immunity, neuroglia and neuroinflammation in autism. Int. Rev. Psychiatry 17, 485-495.
    • (2005) Int. Rev. Psychiatry , vol.17 , pp. 485-495
    • Pardo, C.A.1    Vargas, D.L.2    Zimmerman, A.W.3
  • 127
    • 70449643365 scopus 로고    scopus 로고
    • Flavonoids, a prenatal prophylaxis via targeting JAK2/STAT3 signaling to oppose IL-6/MIA associated autism
    • Parker-Athill, E., Luo, D., Bailey, A., Giunta, B., Tian, J., Shytle, R.D.et al (2009). Flavonoids, a prenatal prophylaxis via targeting JAK2/STAT3 signaling to oppose IL-6/MIA associated autism. J Neuroimmunol. 217, 20-27.
    • (2009) J Neuroimmunol , vol.217 , pp. 20-27
    • Parker-Athill, E.1    Luo, D.2    Bailey, A.3    Giunta, B.4    Tian, J.5    Shytle, R.D.6
  • 128
    • 68349144331 scopus 로고    scopus 로고
    • Bioavailability of flavonoids: a review of their membrane transport and the function of bilitranslocase in animal and plant organisms
    • Passamonti, S., Terdoslavich, M., Franca, R., Vanzo, A., Tramer, F., Braidot, E.et al (2009). Bioavailability of flavonoids: a review of their membrane transport and the function of bilitranslocase in animal and plant organisms. Curr. Drug Metab 10, 369-394.
    • (2009) Curr. Drug Metab , vol.10 , pp. 369-394
    • Passamonti, S.1    Terdoslavich, M.2    Franca, R.3    Vanzo, A.4    Tramer, F.5    Braidot, E.6
  • 129
    • 78649635059 scopus 로고    scopus 로고
    • Flavonols and cardiovascular disease
    • Perez-Vizcaino, F., Duarte, J. (2010b). Flavonols and cardiovascular disease. Mol.Aspects Med 31, 478- 494.
    • (2010) Mol. Aspects Med , vol.31 , pp. 478-494
    • Perez-Vizcaino, F.1    Duarte, J.2
  • 130
    • 78649635059 scopus 로고    scopus 로고
    • Flavonols and cardiovascular disease.
    • Perez-Vizcaino, F., Duarte, J. (2010a). Flavonols and cardiovascular disease. Mol.Aspects Med 31, 478-494.
    • (2010) Mol. Aspects Med , vol.31 , pp. 478-494
    • Perez-Vizcaino, F.1    Duarte, J.2
  • 131
    • 84865853940 scopus 로고    scopus 로고
    • Associations between flavonoids and cardiovascular disease incidence or mortality in European and US populations
    • Peterson, J.J., Dwyer, J.T., Jacques, P.F.and McCullough, M.L. (2012). Associations between flavonoids and cardiovascular disease incidence or mortality in European and US populations. Nutr. Rev 70, 491-508.
    • (2012) Nutr. Rev , vol.70 , pp. 491-508
    • Peterson, J.J.1    Dwyer, J.T.2    Jacques, P.F.3    McCullough, M.L.4
  • 133
    • 70349241517 scopus 로고    scopus 로고
    • Alzheimer's-associated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal
    • Pitt, J., Roth, W., Lacor, P., Smith, A.B., III, Blankenship, M., Velasco, P.et al (2009). Alzheimer's-associated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal. Toxicol. Appl. Pharmacol. 240, 189-197.
    • (2009) Toxicol. Appl. Pharmacol , vol.240 , pp. 189-197
    • Pitt, J.1    Roth, W.2    Lacor, P.3    Smith, A.B.4    III Blankenship, M.5    Velasco, P.6
  • 136
    • 30444446822 scopus 로고    scopus 로고
    • FcepsilonR1 and toll-like receptors mediate synergistic signals to markedly augment production of inflammatory cytokines in murine mast cells
    • Qiao, H., Andrade, M.V., Lisboa, F.A., Morgan, K.and Beaven, M.A. (2006). FcepsilonR1 and toll-like receptors mediate synergistic signals to markedly augment production of inflammatory cytokines in murine mast cells. Blood 107, 610-618.
    • (2006) Blood , vol.107 , pp. 610-618
    • Qiao, H.1    Andrade, M.V.2    Lisboa, F.A.3    Morgan, K.4    Beaven, M.A.5
  • 137
    • 79955777701 scopus 로고    scopus 로고
    • A proposed mechanism for chemotherapy-related cognitive impairment ('chemo-fog')
    • Raffa, R.B. (2011). A proposed mechanism for chemotherapy-related cognitive impairment ('chemo-fog'). J Clin Pharm.Ther 36, 257-259.
    • (2011) J Clin Pharm. Ther , vol.36 , pp. 257-259
    • Raffa, R.B.1
  • 139
    • 84908513705 scopus 로고    scopus 로고
    • Amyloid-beta (Abeta(1-42))-induced paralysis in Caenorhabditis elegans is inhibited by the polyphenol quercetin through activation of protein degradation pathways
    • Regitz, C., Dussling, L.M.and Wenzel, U. (2014). Amyloid-beta (Abeta(1-42))-induced paralysis in Caenorhabditis elegans is inhibited by the polyphenol quercetin through activation of protein degradation pathways. Mol.Nutr.Food Res. 58, 1931-1940.
    • (2014) Mol. Nutr. Food Res. , vol.58 , pp. 1931-1940
    • Regitz, C.1    Dussling, L.M.2    Wenzel, U.3
  • 141
    • 1842784819 scopus 로고    scopus 로고
    • Anxiety and cognition in histamine H3 receptor-/- mice
    • Rizk, A., Curley, J., Robertson, J.and Raber, J. (2004). Anxiety and cognition in histamine H3 receptor-/- mice. Eur.J Neurosci. 19, 1992-1996.
    • (2004) Eur. J Neurosci. , vol.19 , pp. 1992-1996
    • Rizk, A.1    Curley, J.2    Robertson, J.3    Raber, J.4
  • 142
    • 84892365927 scopus 로고    scopus 로고
    • What is brain fog? An evaluation of the symptom in postural tachycardia syndrome
    • Ross, A.J., Medow, M.S., Rowe, P.C.and Stewart, J.M. (2013). What is brain fog? An evaluation of the symptom in postural tachycardia syndrome. Clin Auton.Res. 23, 305-311.
    • (2013) Clin Auton. Res. , vol.23 , pp. 305-311
    • Ross, A.J.1    Medow, M.S.2    Rowe, P.C.3    Stewart, J.M.4
  • 143
    • 84859005372 scopus 로고    scopus 로고
    • A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures
    • Rossignol, D.A., Frye, R.E. (2012). A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures. Mol.Psychiatry 17, 389-401.
    • (2012) Mol.Psychiatry , vol.17 , pp. 389-401
    • Rossignol, D.A.1    Frye, R.E.2
  • 144
    • 0032734056 scopus 로고    scopus 로고
    • Morphological and functional demonstration of rat dura mast cell-neuron interactions in vitro and in vivo
    • Rozniecki, J.J., Dimitriadou, V., Lambracht-Hall, M., Pang, X.and Theoharides, T.C. (1999). Morphological and functional demonstration of rat dura mast cell-neuron interactions in vitro and in vivo. Brain Res 849, 1-15.
    • (1999) Brain Res , vol.849 , pp. 1-15
    • Rozniecki, J.J.1    Dimitriadou, V.2    Lambracht-Hall, M.3    Pang, X.4    Theoharides, T.C.5
  • 145
  • 146
    • 0029945846 scopus 로고    scopus 로고
    • Elevation of the plasma histamine concentration in the coronary circulation in patients with variant angina
    • Sakata, Y., Komamura, K., Hirayama, A., Nanto, S., Kitakaze, M., Hori, M.et al (1996). Elevation of the plasma histamine concentration in the coronary circulation in patients with variant angina. Am. J. Cardiol. 77, 1121-1126.
    • (1996) Am. J. Cardiol , vol.77 , pp. 1121-1126
    • Sakata, Y.1    Komamura, K.2    Hirayama, A.3    Nanto, S.4    Kitakaze, M.5    Hori, M.6
  • 148
    • 34250702156 scopus 로고    scopus 로고
    • Revisiting the ancient concept of botanical therapeutics
    • Schmidt, B.M., Ribnicky, D.M., Lipsky, P.E.and Raskin, I. (2007). Revisiting the ancient concept of botanical therapeutics. Nat Chem Biol 3, 360-366.
    • (2007) Nat Chem Biol , vol.3 , pp. 360-366
    • Schmidt, B.M.1    Ribnicky, D.M.2    Lipsky, P.E.3    Raskin, I.4
  • 149
    • 77955065107 scopus 로고    scopus 로고
    • Histamine intolerance: a metabolic disease?
    • Schwelberger, H.G. (2010). Histamine intolerance: a metabolic disease? Inflamm.Res. 59 Suppl 2, S219- S221.
    • (2010) Inflamm. Res , vol.2 , Issue.59 , pp. S219-S221
    • Schwelberger, H.G.1
  • 150
    • 57149103144 scopus 로고    scopus 로고
    • Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin
    • Seelinger, G., Merfort, I.and Schempp, C.M. (2008). Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin. Planta Med. 74, 1667-1677.
    • (2008) Planta Med. , vol.74 , pp. 1667-1677
    • Seelinger, G.1    Merfort, I.2    Schempp, C.M.3
  • 152
    • 84924578659 scopus 로고    scopus 로고
    • The human histaminergic system in neuropsychiatric disorders
    • Shan, L., Bao, A.M.and Swaab, D.F. (2015). The human histaminergic system in neuropsychiatric disorders. Trends Neurosci. 38, 167-177.
    • (2015) Trends Neurosci. , vol.38 , pp. 167-177
    • Shan, L.1    Bao, A.M.2    Swaab, D.F.3
  • 153
    • 83455255183 scopus 로고    scopus 로고
    • Mast cells as sources and targets of membrane vesicles
    • Shefler, I., Salamon, P., Hershko, A.Y.and Mekori, Y.A. (2011). Mast cells as sources and targets of membrane vesicles. Curr. Pharm. Des 17, 3797-3804.
    • (2011) Curr. Pharm. Des , vol.17 , pp. 3797-3804
    • Shefler, I.1    Salamon, P.2    Hershko, A.Y.3    Mekori, Y.A.4
  • 154
    • 84875007601 scopus 로고    scopus 로고
    • An overview on potential neuroprotective compounds for management of Alzheimer's disease
    • Sheikh, I.A., Ali, R., Dar, T.A.and Kamal, M.A. (2012). An overview on potential neuroprotective compounds for management of Alzheimer's disease. CNS.Neurol. Disord. Drug Targets. 11, 1006-1011.
    • (2012) CNS. Neurol. Disord. Drug Targets. , vol.11 , pp. 1006-1011
    • Sheikh, I.A.1    Ali, R.2    Dar, T.A.3    Kamal, M.A.4
  • 155
    • 34948824845 scopus 로고    scopus 로고
    • Dampness and mold in the home and depression: an examination of mold-related illness and perceived control of one's home as possible depression pathways
    • Shenassa, E.D., Daskalakis, C., Liebhaber, A., Braubach, M.and Brown, M. (2007). Dampness and mold in the home and depression: an examination of mold-related illness and perceived control of one's home as possible depression pathways. Am. J Public Health 97, 1893-1899.
    • (2007) Am. J Public Health , vol.97 , pp. 1893-1899
    • Shenassa, E.D.1    Daskalakis, C.2    Liebhaber, A.3    Braubach, M.4    Brown, M.5
  • 156
    • 84862090639 scopus 로고    scopus 로고
    • 6-Methoxyluteolin from Chrysanthemum zawadskii varlatilobum suppresses histamine release and calcium influx via down-regulation of FcepsilonRI alpha chain expression
    • Shim, S.Y., Park, J.R.and Byun, D.S. (2012). 6-Methoxyluteolin from Chrysanthemum zawadskii var. latilobum suppresses histamine release and calcium influx via down-regulation of FcepsilonRI alpha chain expression. J Microbiol.Biotechnol. 22, 622-627.
    • (2012) J Microbiol. Biotechnol. , vol.22 , pp. 622-627
    • Shim, S.Y.1    Park, J.R.2    Byun, D.S.3
  • 157
    • 33750832370 scopus 로고    scopus 로고
    • Sick building syndrome (SBS) and exposure to water-damaged buildings: time series study, clinical trial and mechanisms
    • Shoemaker, R.C., House, D.E. (2006). Sick building syndrome (SBS) and exposure to water-damaged buildings: time series study, clinical trial and mechanisms. Neurotoxicol. Teratol. 28, 573-588.
    • (2006) Neurotoxicol. Teratol. , vol.28 , pp. 573-588
    • Shoemaker, R.C.1    House, D.E.2
  • 160
    • 84893551659 scopus 로고    scopus 로고
    • Mast cells, glia and neuroinflammation: partners in crime?
    • Skaper, S.D., Facci, L.and Giusti, P. (2013). Mast cells, glia and neuroinflammation: partners in crime? Immunology 141, 314-327.
    • (2013) Immunology , vol.141 , pp. 314-327
    • Skaper, S.D.1    Facci, L.2    Giusti, P.3
  • 161
    • 84864765533 scopus 로고    scopus 로고
    • Microglia and mast cells: two tracks on the road to neuroinflammation
    • Skaper, S.D., Giusti, P.and Facci, L. (2012). Microglia and mast cells: two tracks on the road to neuroinflammation. FASEB J 26, 3103-3117.
    • (2012) FASEB J , vol.26 , pp. 3103-3117
    • Skaper, S.D.1    Giusti, P.2    Facci, L.3
  • 162
    • 0036032980 scopus 로고    scopus 로고
    • Immunoregulatory properties of mast cell derived exosomes
    • Skokos, D., Goubran-Botros, H., Roa, M.and Mecheri, S. (2002). Immunoregulatory properties of mast cell derived exosomes. Mol. Immunol 38, 1359-1362.
    • (2002) Mol. Immunol , vol.38 , pp. 1359-1362
    • Skokos, D.1    Goubran-Botros, H.2    Roa, M.3    Mecheri, S.4
  • 164
    • 35148872226 scopus 로고    scopus 로고
    • Maternal immune activation alters fetal brain development through interleukin-6
    • Smith, S.E., Li, J., Garbett, K., Mirnics, K.and Patterson, P.H. (2007). Maternal immune activation alters fetal brain development through interleukin-6. J.Neurosci. 27, 10695-10702.
    • (2007) J.Neurosci. , vol.27 , pp. 10695-10702
    • Smith, S.E.1    Li, J.2    Garbett, K.3    Mirnics, K.4    Patterson, P.H.5
  • 165
    • 84930816244 scopus 로고    scopus 로고
    • Flavonoid-based therapies in the early management of neurodegenerative diseases
    • Solanki, I., Parihar, P., Mansuri, M.L.and Parihar, M.S. (2015). Flavonoid-based therapies in the early management of neurodegenerative diseases. Adv.Nutr. 6, 64-72.
    • (2015) Adv. Nutr. , vol.6 , pp. 64-72
    • Solanki, I.1    Parihar, P.2    Mansuri, M.L.3    Parihar, M.S.4
  • 167
    • 84926215488 scopus 로고    scopus 로고
    • Autocrine hemokinin-1 functions as an endogenous adjuvant for IgE-mediated mast cell inflammatory responses
    • Sumpter, T.L., Ho, C.H., Pleet, A.R., Tkacheva, O.A., Shufesky, W.J., Rojas-Canales, D.M.et al (2015). Autocrine hemokinin-1 functions as an endogenous adjuvant for IgE-mediated mast cell inflammatory responses. J Allergy Clin Immunol 135, 1019-1030.
    • (2015) J Allergy Clin Immunol , vol.135 , pp. 1019-1030
    • Sumpter, T.L.1    Ho, C.H.2    Pleet, A.R.3    Tkacheva, O.A.4    Shufesky, W.J.5    Rojas-Canales, D.M.6
  • 168
    • 84932084095 scopus 로고    scopus 로고
    • Relationship between adipoq gene polymorphism and lipid levels and diabetes
    • Sun, Y., Li, D.G., Li, Q., Huang, L., He, Z., Zhang, F.et al (2015). Relationship between adipoq gene polymorphism and lipid levels and diabetes. J Biol.Regul.Homeost.Agents 29, 221-227.
    • (2015) J Biol.Regul.Homeost.Agents , vol.29 , pp. 221-227
    • Sun, Y.1    Li, D.G.2    Li, Q.3    Huang, L.4    He, Z.5    Zhang, F.6
  • 169
    • 84877905373 scopus 로고    scopus 로고
    • An open-label pilot study of a formulation containing the anti-inflammatory flavonoid luteolin and its effects on behavior in children with autism spectrum disorders
    • Taliou, A., Zintzaras, E., Lykouras, L.and Francis, K. (2013). An open-label pilot study of a formulation containing the anti-inflammatory flavonoid luteolin and its effects on behavior in children with autism spectrum disorders. Clin Ther 35, 592-602.
    • (2013) Clin Ther , vol.35 , pp. 592-602
    • Taliou, A.1    Zintzaras, E.2    Lykouras, L.3    Francis, K.4
  • 170
    • 77953827925 scopus 로고    scopus 로고
    • Inflammation in the Alzheimer's disease cascade: culprit or innocent bystander?
    • Tan, Z.S., Seshadri, S. (2010). Inflammation in the Alzheimer's disease cascade: culprit or innocent bystander? Alzheimers.Res.Ther 2, 6.
    • (2010) Alzheimers.Res.Ther , vol.2 , pp. 6
    • Tan, Z.S.1    Seshadri, S.2
  • 172
    • 0025055444 scopus 로고
    • Mast cells: the immune gate to the brain
    • Theoharides, T.C. (1990). Mast cells: the immune gate to the brain. Life Sci 46, 607-617.
    • (1990) Life Sci , vol.46 , pp. 607-617
    • Theoharides, T.C.1
  • 173
    • 76349105709 scopus 로고    scopus 로고
    • Autism spectrum disorders and mastocytosis
    • Theoharides, T.C. (2009). Autism spectrum disorders and mastocytosis. Int J Immunopathol Pharmacol 22, 859-865.
    • (2009) Int J Immunopathol Pharmacol , vol.22 , pp. 859-865
    • Theoharides, T.C.1
  • 174
    • 84877915647 scopus 로고    scopus 로고
    • Atopic conditions in search of pathogenesis and therapy
    • Theoharides, T.C. (2013a). Atopic conditions in search of pathogenesis and therapy. Clin Ther 35, 544- 547.
    • (2013) Clin Ther , vol.35 , pp. 544- 547
    • Theoharides, T.C.1
  • 175
    • 84877904095 scopus 로고    scopus 로고
    • Is a subtype of autism "allergy of the brain"?
    • Theoharides, T.C. (2013b). Is a subtype of autism "allergy of the brain"? Clin. Ther. 35, 584-591.
    • (2013) Clin. Ther. , vol.35 , pp. 584-591
    • Theoharides, T.C.1
  • 176
    • 84931003808 scopus 로고    scopus 로고
    • Mast cells promote malaria infection?
    • in press
    • Theoharides, T.C. (2015). Mast cells promote malaria infection? Clin Ther in press.
    • (2015) Clin Ther
    • Theoharides, T.C.1
  • 179
    • 84863725814 scopus 로고    scopus 로고
    • Unwanted interactions among psychotropic drugs and other treatments for Autism Spectrum Disorders
    • Theoharides, T.C., Asadi, S. (2012). Unwanted interactions among psychotropic drugs and other treatments for Autism Spectrum Disorders. J Clin. Psychopharmacol. 32, 437-440.
    • (2012) J Clin. Psychopharmacol. , vol.32 , pp. 437-440
    • Theoharides, T.C.1    Asadi, S.2
  • 180
    • 84863708123 scopus 로고    scopus 로고
    • A case series of a luteolin formulation (NeuroProtek(R)) in children with autism spectrum disorders
    • Theoharides, T.C., Asadi, S.and Panagiotidou, S. (2012). A case series of a luteolin formulation (NeuroProtek(R)) in children with autism spectrum disorders. Int J Immunopathol Pharmacol 25, 317-323.
    • (2012) Int J Immunopathol Pharmacol , vol.25 , pp. 317-323
    • Theoharides, T.C.1    Asadi, S.2    Panagiotidou, S.3
  • 182
    • 0020319742 scopus 로고
    • Differential release of serotonin and histamine from mast cells
    • Theoharides, T.C., Bondy, P.K., Tsakalos, N.D.and Askenase, P.W. (1982). Differential release of serotonin and histamine from mast cells. Nature 297, 229-231.
    • (1982) Nature , vol.297 , pp. 229-231
    • Theoharides, T.C.1    Bondy, P.K.2    Tsakalos, N.D.3    Askenase, P.W.4
  • 183
    • 0347993174 scopus 로고    scopus 로고
    • Critical role of mast cells in inflammatory diseases and the effect of acute stress
    • Theoharides, T.C., Cochrane, D.E. (2004b). Critical role of mast cells in inflammatory diseases and the effect of acute stress. J Neuroimmunol 146, 1-12.
    • (2004) J Neuroimmunol , vol.146 , pp. 1-12
    • Theoharides, T.C.1    Cochrane, D.E.2
  • 184
    • 0347993174 scopus 로고    scopus 로고
    • Critical role of mast cells in inflammatory diseases and the effect of acute stress
    • Theoharides, T.C., Cochrane, D.E. (2004a). Critical role of mast cells in inflammatory diseases and the effect of acute stress. J Neuroimmunol. 146, 1-12.
    • (2004) J Neuroimmunol , vol.146 , pp. 1-12
    • Theoharides, T.C.1    Cochrane, D.E.2
  • 185
    • 84896393412 scopus 로고    scopus 로고
    • Brain inflammation, neuropsychiatric disorders, and immunoendocrine effects of luteolin
    • Theoharides, T.C., Conti, P.and Economu, M. (2014). Brain inflammation, neuropsychiatric disorders, and immunoendocrine effects of luteolin. J Clin Psychopharmacol 34, 187-189.
    • (2014) J Clin Psychopharmacol , vol.34 , pp. 187-189
    • Theoharides, T.C.1    Conti, P.2    Economu, M.3
  • 187
    • 0018188706 scopus 로고
    • Secretion in mast cells induced by calcium entrapped within phospholipid vesicles
    • Theoharides, T.C., Douglas, W.W. (1978). Secretion in mast cells induced by calcium entrapped within phospholipid vesicles. Science 201, 1143-1145.
    • (1978) Science , vol.201 , pp. 1143-1145
    • Theoharides, T.C.1    Douglas, W.W.2
  • 189
    • 34248137929 scopus 로고    scopus 로고
    • Differential release of mast cell mediators and the pathogenesis of inflammation
    • Theoharides, T.C., Kempuraj, D., Tagen, M., Conti, P.and Kalogeromitros, D. (2007). Differential release of mast cell mediators and the pathogenesis of inflammation. Immunol Rev 217, 65-78.
    • (2007) Immunol Rev , vol.217 , pp. 65-78
    • Theoharides, T.C.1    Kempuraj, D.2    Tagen, M.3    Conti, P.4    Kalogeromitros, D.5
  • 190
    • 34248150697 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone and the blood-brain barrier
    • Theoharides, T.C., Konstantinidou, A. (2007). Corticotropin-releasing hormone and the blood-brain barrier. Front Biosci 12, 1615-1628.
    • (2007) Front Biosci , vol.12 , pp. 1615-1628
    • Theoharides, T.C.1    Konstantinidou, A.2
  • 192
    • 0028866220 scopus 로고
    • Stress-induced intracranial mast cell degranulation. A corticotropin releasing hormone-mediated effect
    • Theoharides, T.C., Spanos, C.P., Pang, X., Alferes, L., Ligris, K., Letourneau, R.et al ( 1995). Stress-induced intracranial mast cell degranulation. A corticotropin releasing hormone-mediated effect. Endocrinology 136, 5745-5750.
    • (1995) Endocrinology , vol.136 , pp. 5745-5750
    • Theoharides, T.C.1    Spanos, C.P.2    Pang, X.3    Alferes, L.4    Ligris, K.5    Letourneau, R.6
  • 194
  • 196
    • 80755163162 scopus 로고    scopus 로고
    • Decreased mitochondrial function and increased brain inflammation in bipolar disorder and other neuropsychiatric diseases
    • Theoharides, T.C., Zhang, B.and Conti, P. (2011b). Decreased mitochondrial function and increased brain inflammation in bipolar disorder and other neuropsychiatric diseases. J Clin Psychopharmacol. 31, 685- 687.
    • (2011) J Clin Psychopharmacol , vol.31 , pp. 685-687
    • Theoharides, T.C.1    Zhang, B.2    Conti, P.3
  • 197
    • 77749279720 scopus 로고    scopus 로고
    • IL-33 augments substance P-induced VEGF secretion from human mast cells and is increased in psoriatic skin
    • Theoharides, T.C., Zhang, B., Kempuraj, D., Tagen, M., Vasiadi, M., Angelidou, A.et al (2010). IL-33 augments substance P-induced VEGF secretion from human mast cells and is increased in psoriatic skin. Proc Natl Acad Sci U S A 107, 4448-4453.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 4448-4453
    • Theoharides, T.C.1    Zhang, B.2    Kempuraj, D.3    Tagen, M.4    Vasiadi, M.5    Angelidou, A.6
  • 198
    • 84883430076 scopus 로고    scopus 로고
    • Flavonoid bioavailability and attempts for bioavailability enhancement
    • Thilakarathna, S.H., Rupasinghe, H.P. (2013). Flavonoid bioavailability and attempts for bioavailability enhancement. Nutrients. 5, 3367-3387.
    • (2013) Nutrients. , vol.5 , pp. 3367-3387
    • Thilakarathna, S.H.1    Rupasinghe, H.P.2
  • 200
    • 33947379200 scopus 로고    scopus 로고
    • Effects of luteolin on learning acquisition in rats: involvement of the central cholinergic system
    • Tsai, F.S., Peng, W.H., Wang, W.H., Wu, C.R., Hsieh, C.C., Lin, Y.T.et al (2007). Effects of luteolin on learning acquisition in rats: involvement of the central cholinergic system. Life Sci. 80, 1692-1698.
    • (2007) Life Sci , vol.80 , pp. 1692-1698
    • Tsai, F.S.1    Peng, W.H.2    Wang, W.H.3    Wu, C.R.4    Hsieh, C.C.5    Lin, Y.T.6
  • 201
    • 84902824600 scopus 로고    scopus 로고
    • Exosomes in neurologic and psychiatric disorders
    • Tsilioni, I., Panagiotidou, S.and Theoharides, T.C. (2014). Exosomes in neurologic and psychiatric disorders. Clin. Ther. 36, 882-888.
    • (2014) Clin. Ther. , vol.36 , pp. 882-888
    • Tsilioni, I.1    Panagiotidou, S.2    Theoharides, T.C.3
  • 202
    • 84935108808 scopus 로고    scopus 로고
    • World Population Prospects:The 2010 Revision
    • United Nations, Department of Economic and Social Affairs Population Division, http:, and esa.un.org/wpp/documentation/WPP%202010%20publications.htm. World Population Prospects:The 2010 Revision. 2015.
    • (2015)
  • 203
    • 79959598455 scopus 로고    scopus 로고
    • Definitions, criteria and global classification of mast cell disorders with special reference to mast cell activation syndromes: a consensus proposal
    • Valent, P., Akin, C., Arock, M., Brockow, K., Butterfield, J.H., Carter, M.C.et al (2012). Definitions, criteria and global classification of mast cell disorders with special reference to mast cell activation syndromes: a consensus proposal. Int Arch Allergy Immunol 157, 215-225.
    • (2012) Int Arch Allergy Immunol , vol.157 , pp. 215-225
    • Valent, P.1    Akin, C.2    Arock, M.3    Brockow, K.4    Butterfield, J.H.5    Carter, M.C.6
  • 204
    • 84896366752 scopus 로고    scopus 로고
    • Effect of flavonoids on learning, memory and neurocognitive performance: relevance and potential implications for Alzheimer's disease pathophysiology
    • Vauzour, D. (2014). Effect of flavonoids on learning, memory and neurocognitive performance: relevance and potential implications for Alzheimer's disease pathophysiology. J Sci. Food Agric. 94, 1042-1056.
    • (2014) J Sci. Food Agric. , vol.94 , pp. 1042-1056
    • Vauzour, D.1
  • 205
    • 3242720446 scopus 로고    scopus 로고
    • The flavones luteolin and apigenin inhibit in vitro antigen-specific proliferation and interferon-gamma production by murine and human autoimmune T cells
    • Verbeek, R., Plomp, A.C., van Tol, E.A.and van Noort, J.M. (2004). The flavones luteolin and apigenin inhibit in vitro antigen-specific proliferation and interferon-gamma production by murine and human autoimmune T cells. Biochem. Pharmacol. 68, 621-629.
    • (2004) Biochem. Pharmacol. , vol.68 , pp. 621-629
    • Verbeek, R.1    Plomp, A.C.2    van Tol, E.A.3    van Noort, J.M.4
  • 206
    • 37549024168 scopus 로고    scopus 로고
    • Methylation of dietary flavones greatly improves their hepatic metabolic stability and intestinal absorption
    • Walle, T. (2007). Methylation of dietary flavones greatly improves their hepatic metabolic stability and intestinal absorption. Mol. Pharm 4, 826-832.
    • (2007) Mol. Pharm , vol.4 , pp. 826-832
    • Walle, T.1
  • 207
    • 84905699874 scopus 로고    scopus 로고
    • Effects of long-term treatment with quercetin on cognition and mitochondrial function in a mouse model of Alzheimer's disease
    • Wang, D.M., Li, S.Q., Wu, W.L., Zhu, X.Y., Wang, Y.and Yuan, H.Y. (2014). Effects of long-term treatment with quercetin on cognition and mitochondrial function in a mouse model of Alzheimer's disease. Neurochem. Res. 39, 1533-1543.
    • (2014) Neurochem. Res. , vol.39 , pp. 1533-1543
    • Wang, D.M.1    Li, S.Q.2    Wu, W.L.3    Zhu, X.Y.4    Wang, Y.5    Yuan, H.Y.6
  • 208
    • 84898025878 scopus 로고    scopus 로고
    • Absolute bioavailability, pharmacokinetics and excretion of 5, 7, 30, 40 -tetramethoxyflavone in rats
    • Wei, G., Hwang, L.and Tsai, C. (2014). Absolute bioavailability, pharmacokinetics and excretion of 5, 7, 30, 40 -tetramethoxyflavone in rats. J Functional Foods 7, 136-141.
    • (2014) J Functional Foods , vol.7 , pp. 136-141
    • Wei, G.1    Hwang, L.2    Tsai, C.3
  • 209
    • 84927535942 scopus 로고    scopus 로고
    • The novel flavone tetramethoxyluteolin is a potent inhibitor of human mast cells
    • Weng Z, Patel A, Panagiotidou Sand Theoharides TC (2014). The novel flavone tetramethoxyluteolin is a potent inhibitor of human mast cells. J Allergy Clin Immunol 14, 01574-01577.
    • (2014) J Allergy Clin Immunol , vol.14 , pp. 01574-01577
    • Weng, Z.1    Patel, A.2    Panagiotidou, S.3    Theoharides, T.C.4
  • 210
    • 27844461127 scopus 로고    scopus 로고
    • Central nervous system neurons acquire mast cell products via transgranulation
    • Wilhelm, M., Silver, R.and Silverman, A.J. (2005). Central nervous system neurons acquire mast cell products via transgranulation. Eur. J Neurosci. 22, 2238-2248.
    • (2005) Eur. J Neurosci. , vol.22 , pp. 2238-2248
    • Wilhelm, M.1    Silver, R.2    Silverman, A.J.3
  • 211
    • 84901933225 scopus 로고    scopus 로고
    • Alzheimer's disease: evidence for the expression of interleukin-33 and its receptor ST2 in the brain
    • Xiong, Z., Thangavel, R., Kempuraj, D., Yang, E., Zaheer, S.and Zaheer, A. (2014). Alzheimer's disease: evidence for the expression of interleukin-33 and its receptor ST2 in the brain. J Alzheimers. Dis. 40, 297- 308.
    • (2014) J Alzheimers. Dis. , vol.40 , pp. 297- 308
    • Xiong, Z.1    Thangavel, R.2    Kempuraj, D.3    Yang, E.4    Zaheer, S.5    Zaheer, A.6
  • 212
    • 84901944300 scopus 로고    scopus 로고
    • Low-dose diet supplement of a natural flavonoid, luteolin, ameliorates diet-induced obesity and insulin resistance in mice
    • Xu, N., Zhang, L., Dong, J., Zhang, X., Chen, Y.G., Bao, B.et al (2014). Low-dose diet supplement of a natural flavonoid, luteolin, ameliorates diet-induced obesity and insulin resistance in mice. Mol. Nutr. Food Res. 58, 1258-1268.
    • (2014) Mol. Nutr. Food Res , vol.58 , pp. 1258-1268
    • Xu, N.1    Zhang, L.2    Dong, J.3    Zhang, X.4    Chen, Y.G.5    Bao, B.6
  • 213
    • 84880202236 scopus 로고    scopus 로고
    • Flavonoids induce the synthesis and secretion of neurotrophic factors in cultured rat astrocytes: a signaling response mediated by estrogen receptor
    • Xu, S.L., Bi, C.W., Choi, R.C., Zhu, K.Y., Miernisha, A., Dong, T.T.et al (2013). Flavonoids induce the synthesis and secretion of neurotrophic factors in cultured rat astrocytes: a signaling response mediated by estrogen receptor. Evid. Based. Complement Alternat. Med. 2013, 127075.
    • (2013) Evid. Based. Complement Alternat. Med , vol.2013 , pp. 127075
    • Xu, S.L.1    Bi, C.W.2    Choi, R.C.3    Zhu, K.Y.4    Miernisha, A.5    Dong, T.T.6
  • 214
    • 84908567143 scopus 로고    scopus 로고
    • The combined role of serotonin and interleukin-6 as biomarker for autism
    • Yang, C.J., Liu, C.L., Sang, B., Zhu, X.M.and Du, Y.J. (2015). The combined role of serotonin and interleukin-6 as biomarker for autism. Neuroscience 284, 290-296.
    • (2015) Neuroscience , vol.284 , pp. 290-296
    • Yang, C.J.1    Liu, C.L.2    Sang, B.3    Zhu, X.M.4    Du, Y.J.5
  • 215
    • 84874591436 scopus 로고    scopus 로고
    • Polyphenols differentially inhibit degranulation of distinct subsets of vesicles in mast cells by specific interaction with granule-type dependent SNARE complexes
    • Yang, Y., Oh, J.M., Heo, P., Shin, J.Y., Kong, B., Shin, J.et al (2013). Polyphenols differentially inhibit degranulation of distinct subsets of vesicles in mast cells by specific interaction with granule-type dependent SNARE complexes. Biochem. J 450, 537-546.
    • (2013) Biochem. J , vol.450 , pp. 537-546
    • Yang, Y.1    Oh, J.M.2    Heo, P.3    Shin, J.Y.4    Kong, B.5    Shin, J.6
  • 216
    • 78651494308 scopus 로고    scopus 로고
    • Effects of resveratrol and flavonols on cardiovascular function: Physiological mechanisms
    • Yap, S., Qin, C.and Woodman, O.L. (2010). Effects of resveratrol and flavonols on cardiovascular function: Physiological mechanisms. Biofactors 36, 350-359.
    • (2010) Biofactors , vol.36 , pp. 350-359
    • Yap, S.1    Qin, C.2    Woodman, O.L.3
  • 217
    • 84884174276 scopus 로고    scopus 로고
    • Effects of luteolin on spatial memory, cell proliferation, and neuroblast differentiation in the hippocampal dentate gyrus in a scopolamine-induced amnesia model
    • Yoo, D.Y., Choi, J.H., Kim, W., Nam, S.M., Jung, H.Y., Kim, J.H.et al (2013). Effects of luteolin on spatial memory, cell proliferation, and neuroblast differentiation in the hippocampal dentate gyrus in a scopolamine-induced amnesia model. Neurol. Res. 35, 813-820.
    • (2013) Neurol. Res , vol.35 , pp. 813-820
    • Yoo, D.Y.1    Choi, J.H.2    Kim, W.3    Nam, S.M.4    Jung, H.Y.5    Kim, J.H.6
  • 218
    • 79957839365 scopus 로고    scopus 로고
    • Human mast cell degranulation and preformed TNF secretion require mitochondrial translocation to exocytosis sites: Relevance to atopic dermatitis
    • Zhang, B., Alysandratos, K.D., Angelidou, A., Asadi, S., Sismanopoulos, N., Delivanis, D.A.et al (2011). Human mast cell degranulation and preformed TNF secretion require mitochondrial translocation to exocytosis sites: Relevance to atopic dermatitis. J Allergy Clin Immunol 127, 1522-1531.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 1522-1531
    • Zhang, B.1    Alysandratos, K.D.2    Angelidou, A.3    Asadi, S.4    Sismanopoulos, N.5    Delivanis, D.A.6
  • 219
    • 84871326101 scopus 로고    scopus 로고
    • Stimulated human mast cells secrete mitochondrial components that have autocrine and paracrine inflammatory actions
    • Zhang, B., Asadi, S., Weng, Z., Sismanopoulos, N.and Theoharides, T.C. (2012). Stimulated human mast cells secrete mitochondrial components that have autocrine and paracrine inflammatory actions. PloS One 7, e49767.
    • (2012) PloS One , vol.7
    • Zhang, B.1    Asadi, S.2    Weng, Z.3    Sismanopoulos, N.4    Theoharides, T.C.5
  • 220
    • 84860583269 scopus 로고    scopus 로고
    • Mitochondria distinguish granule-stored from de novo synthesized tumor necrosis factor secretion in human mast cells
    • Zhang, B., Weng, Z., Sismanopoulos, N., Asadi, S., Therianou, A., Alysandratos, K.D.et al (2012). Mitochondria distinguish granule-stored from de novo synthesized tumor necrosis factor secretion in human mast cells. Int Arch. Allergy Immunol 159, 23-32.
    • (2012) Int Arch. Allergy Immunol , vol.159 , pp. 23-32
    • Zhang, B.1    Weng, Z.2    Sismanopoulos, N.3    Asadi, S.4    Therianou, A.5    Alysandratos, K.D.6
  • 221
    • 79958037012 scopus 로고    scopus 로고
    • Luteolin inhibits microglial inflammation and improves neuron survival against inflammation
    • Zhu, L.H., Bi, W., Qi, R.B., Wang, H.D.and Lu, D.X. (2011). Luteolin inhibits microglial inflammation and improves neuron survival against inflammation. Int J Neurosci. 121, 329-336.
    • (2011) Int J Neurosci. , vol.121 , pp. 329-336
    • Zhu, L.H.1    Bi, W.2    Qi, R.B.3    Wang, H.D.4    Lu, D.X.5
  • 222
    • 84872532360 scopus 로고    scopus 로고
    • Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's Disease
    • Zhu, X., Perry, G., Smith, M.A.and Wang, X. (2012). Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's Disease. J Alzheimers. Dis. 33, S253-S262.
    • (2012) J Alzheimers. Dis. , vol.33 , pp. S253-S262
    • Zhu, X.1    Perry, G.2    Smith, M.A.3    Wang, X.4
  • 223
    • 80053574021 scopus 로고    scopus 로고
    • Treatment of brain inflammatory diseases by delivering exosome encapsulated anti-inflammatory drugs from the nasal region to the brain
    • Zhuang, X., Xiang, X., Grizzle, W., Sun, D., Zhang, S., Axtell, R.C.et al (2011). Treatment of brain inflammatory diseases by delivering exosome encapsulated anti-inflammatory drugs from the nasal region to the brain. Mol. Ther. 19, 1769-1779.
    • (2011) Mol. Ther , vol.19 , pp. 1769-1779
    • Zhuang, X.1    Xiang, X.2    Grizzle, W.3    Sun, D.4    Zhang, S.5    Axtell, R.C.6


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