Identification of brain-targeted bioactive dietary quercetin-3-O- glucuronide as a novel intervention for Alzheimer's disease

FASEB Journal

Volumn 27, Issue 2, 2013, Pages 769-781

  Ho, Lap ^a   Ferruzzi, Mario G ^c,d   Janle, Elsa M ^d   Wang, Jun ^a   Gong, Bing ^a   Chen, Tzu Ying ^d   Lobo, Jessica ^c   Cooper, Bruce ^e   Wu, Qing Li ^f   Talcott, Stephen T ^g   Percival, Susan S ^h   Simon, James E ^f   Pasinetti, Giulio Maria ^a,b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c Purdue University ^*  (United States)

^d PURDUE UNIVERSITY   (United States)

^e PURDUE UNIVERSITY   (United States)

^f RUTGERS UNIVERSITY   (United States)

^g TEXAS A AND M UNIVERSITY   (United States)

^h UNIVERSITY OF FLORIDA   (United States)

Author keywords

Cognitive deterioration; Neuroplasticity; Polyphenol bioavailability

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; ANTHOCYANIN; CATECHIN; EPICATECHIN; FLAVONOL DERIVATIVE; GALLIC ACID; GLUCURONIDE; MALVIDIN CHLORIDE; MITOGEN ACTIVATED PROTEIN KINASE; PARA COUMARIC ACID; POLYPHENOL DERIVATIVE; PROANTHOCYANIDIN DERIVATIVE; QUERCETIN 3 O GLUCURONIDE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; VANILLIC ACID;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BIOAVAILABILITY; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG BLOOD LEVEL; ENZYME ACTIVATION; HIPPOCAMPUS; IN VITRO STUDY; LONG TERM POTENTIATION; MEMORY; MOUSE; NERVE CELL CULTURE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; RAT; RED WINE; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

ADMINISTRATION, ORAL; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; ANTHOCYANINS; BIOLOGICAL AVAILABILITY; BRAIN; CELLS, CULTURED; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; HUMANS; MALE; MICE; MICE, TRANSGENIC; NEURONAL PLASTICITY; NEURONS; NEUROPROTECTIVE AGENTS; POLYPHENOLS; PROTEIN MULTIMERIZATION; QUERCETIN; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; WINE;

EID: 84873455519     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-212118     Document Type: Article

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