Rupatadine effectively prevents the histamine-induced up regulation of histamine H1R and bradykinin B2R receptor gene expression in the rat paw

Pharmacological Reports

Volumn 66, Issue 6, 2014, Pages 952-955

  Molyva, Dimitra ^a   Kalokasidis, Konstantinos ^a   Poulios, Christos ^a   Dedi, Hara ^a   Karkavelas, George ^a   Mirtsou, Vassiliki ^a   Goulas, Antonis ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Bradykinin receptors; Gene expression; Histamine H1 receptor; Rat paw; Rupatadine

Indexed keywords

APAFANT; BRADYKININ B2 RECEPTOR; HISTAMINE; HISTAMINE H1 RECEPTOR; METHYLPREDNISOLONE; METHYLPREDNISOLONE SODIUM SUCCINATE; RUPATADINE; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; BRADYKININ B1 RECEPTOR; CYPROHEPTADINE; HISTAMINE H1 RECEPTOR ANTAGONIST; EOSIN; HEMATOXYLIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B1R GENE; B2R GENE; CELL INFILTRATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; GENE EXPRESSION REGULATION; H1R GENE; MALE; NONHUMAN; OUTCOME ASSESSMENT; PAW EDEMA; POLYMORPHONUCLEAR CELL; PREMEDICATION; RAT; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT RESPONSE; ANALOGS AND DERIVATIVES; ANIMAL; DRUG EFFECTS; EDEMA; GENETICS; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; ALLERGY; EXPERIMENTAL MODEL; GENE EXPRESSION; MICROSCOPY; PLETHYSMOGRAPHY; POLYMERASE CHAIN REACTION; RECEPTOR GENE; SINGLE DRUG DOSE; STAINING; TISSUE SECTION; TISSUE STRUCTURE;

ANIMALS; CYPROHEPTADINE; EDEMA; GENE EXPRESSION REGULATION; HISTAMINE; HISTAMINE H1 ANTAGONISTS; RATS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, BRADYKININ B1; RECEPTOR, BRADYKININ B2; RECEPTORS, HISTAMINE H1; UP-REGULATION;

EID: 84905851370     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/j.pharep.2014.06.008     Document Type: Article

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