-
2
-
-
0034568811
-
Freiherr von Pirquet: Explaining immune complex disease in 1906
-
Silverstein, A. M. Clemens Freiherr von Pirquet: explaining immune complex disease in 1906. Nature Immunol. 1, 453-455 (2000).
-
(2000)
Nature Immunol
, vol.1
, pp. 453-455
-
-
Silverstein, A.1
Clemens, M.2
-
3
-
-
0033604596
-
The epidemic of allergy and asthma
-
Holgate, S. T. The epidemic of allergy and asthma. Nature 402, B2-B4 (1999).
-
(1999)
Nature
, vol.402
-
-
Holgate, S.T.1
-
4
-
-
0035804276
-
Allergy and allergic diseases. First of two parts
-
Kay, A. B. Allergy and allergic diseases. First of two parts. N. Engl. J. Med. 344, 30-37 (2001).
-
(2001)
N. Engl. J. Med
, vol.344
, pp. 30-37
-
-
Kay, A.B.1
-
5
-
-
33751213587
-
The asthma epidemic
-
Eder, W., Ege, M. J. & von Mutius, E. The asthma epidemic. N. Engl. J. Med. 355, 2226-2235 (2006).
-
(2006)
N. Engl. J. Med
, vol.355
, pp. 2226-2235
-
-
Eder, W.1
Ege, M.J.2
von Mutius, E.3
-
6
-
-
20044367464
-
Symposium on the definition and management of anaphylaxis: Summary report
-
Sampson, H. A. et al. Symposium on the definition and management of anaphylaxis: summary report. J. Allergy Clin. Immunol. 115, 584-591 (2005).
-
(2005)
J. Allergy Clin. Immunol
, vol.115
, pp. 584-591
-
-
Sampson, H.A.1
-
7
-
-
33750285456
-
New therapies for asthma
-
Barnes, P. J. New therapies for asthma. Trends Mol. Med. 12, 515-520 (2006).
-
(2006)
Trends Mol. Med
, vol.12
, pp. 515-520
-
-
Barnes, P.J.1
-
8
-
-
34247572895
-
New developments in FcεRI regulation, function and inhibition
-
This review of FcεRI-dependent signalling in mast cells and basophils considers how the biology and functional properties of FcεRI might be exploited for the development of new therapeutics
-
Kraft, S. & Kinet, J. P. New developments in FcεRI regulation, function and inhibition. Nature Rev. Immunol. 7, 365-378 (2007). This review of FcεRI-dependent signalling in mast cells and basophils considers how the biology and functional properties of FcεRI might be exploited for the development of new therapeutics.
-
(2007)
Nature Rev. Immunol
, vol.7
, pp. 365-378
-
-
Kraft, S.1
Kinet, J.P.2
-
9
-
-
40049092917
-
Treatment strategies for allergy and asthma
-
Holgate, S. T. & Polosa, R. Treatment strategies for allergy and asthma. Nature Rev. Immunol. 8, 218-230 (2008).
-
(2008)
Nature Rev. Immunol
, vol.8
, pp. 218-230
-
-
Holgate, S.T.1
Polosa, R.2
-
10
-
-
33749016485
-
Immunological mechanisms of allergen-specific immunotherapy
-
This review discusses the history, immunological mechanisms and future prospects of improving allergen-specific immunotherapy
-
Larché, M., Akdis, C. A. & Valenta, R. Immunological mechanisms of allergen-specific immunotherapy. Nature Rev. Immunol. 6, 761-771 (2006). This review discusses the history, immunological mechanisms and future prospects of improving allergen-specific immunotherapy.
-
(2006)
Nature Rev. Immunol
, vol.6
, pp. 761-771
-
-
Larché, M.1
Akdis, C.A.2
Valenta, R.3
-
11
-
-
34047163404
-
Mechanisms of allergen-specific immunotherapy
-
Akdis, M. & Akdis, C. A. Mechanisms of allergen-specific immunotherapy. J. Allergy Clin. Immunol. 119, 780-791 (2007).
-
(2007)
J. Allergy Clin. Immunol
, vol.119
, pp. 780-791
-
-
Akdis, M.1
Akdis, C.A.2
-
12
-
-
33845951414
-
Probiotics and prebiotic galacto- oligosaccharides in the prevention of allergic diseases: A randomized, double-blind, placebo-controlled trial
-
Kukkonen, K. et al. Probiotics and prebiotic galacto- oligosaccharides in the prevention of allergic diseases: a randomized, double-blind, placebo-controlled trial. J. Allergy Clin. Immunol. 119, 192-198 (2007).
-
(2007)
J. Allergy Clin. Immunol
, vol.119
, pp. 192-198
-
-
Kukkonen, K.1
-
13
-
-
0037134046
-
Allergy, parasites, and the hygiene hypothesis
-
Yazdanbakhsh, M., Kremsner, P. G. & van Ree, R. Allergy, parasites, and the hygiene hypothesis. Science 296, 490-494 (2002).
-
(2002)
Science
, vol.296
, pp. 490-494
-
-
Yazdanbakhsh, M.1
Kremsner, P.G.2
van Ree, R.3
-
14
-
-
84945516007
-
-
Galli, S. J. & Askenase, P. W. in The Reticuloendothelial System: A Comprehensive Treatise IX: Hypersensitivity (eds Abramoff, P., Phillips, S. M. & Escobar, M. R.) 321-369 (Plenum, 1986).
-
Galli, S. J. & Askenase, P. W. in The Reticuloendothelial System: A Comprehensive Treatise Vol. IX: Hypersensitivity (eds Abramoff, P., Phillips, S. M. & Escobar, M. R.) 321-369 (Plenum, 1986).
-
-
-
-
15
-
-
33847175843
-
H2-type allergic reactions by helminth infection
-
H2-type allergic reactions by helminth infection. Nature Rev. Immunol. 7, 220-230 (2007).
-
(2007)
Nature Rev. Immunol
, vol.7
, pp. 220-230
-
-
Fallon, P.G.1
Mangan, N.E.2
-
16
-
-
17144405680
-
-
Hawrylowicz, C. M. & O'Garra, A. Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma. Nature Rev. Immunol. 5, 271-283 (2005). This review provides an introduction to the mechanisms by which regulatory T cells that produce the anti-inflammatory and immunosuppressive cytokine IL-10 might limit the pathology associated with allergy and allergic inflammation of the airways in asthma.
-
Hawrylowicz, C. M. & O'Garra, A. Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma. Nature Rev. Immunol. 5, 271-283 (2005). This review provides an introduction to the mechanisms by which regulatory T cells that produce the anti-inflammatory and immunosuppressive cytokine IL-10 might limit the pathology associated with allergy and allergic inflammation of the airways in asthma.
-
-
-
-
17
-
-
34249799275
-
Coming back to a missing immune deviation as the main explanatory mechanism for the hygiene hypothesis
-
Romagnani, S. Coming back to a missing immune deviation as the main explanatory mechanism for the hygiene hypothesis. J. Allergy Clin. Immunol. 119, 1511-1513 (2007).
-
(2007)
J. Allergy Clin. Immunol
, vol.119
, pp. 1511-1513
-
-
Romagnani, S.1
-
18
-
-
10244250341
-
The immunogenetics of asthma and eczema: A new focus on the epithelium
-
Cookson, W. The immunogenetics of asthma and eczema: a new focus on the epithelium. Nature Rev. Immunol. 4, 978-988 (2004).
-
(2004)
Nature Rev. Immunol
, vol.4
, pp. 978-988
-
-
Cookson, W.1
-
19
-
-
40049100646
-
-
Vercelli, D. Discovering susceptibility genes for asthma and allergy. Nature Rev. Immunol. 8, 169-182 (2008). This review presents the current understanding of the many genes that have been implicated in asthma and allergy, including evidence that exposure to the same microbial products may have opposite effects on susceptibility to developing allergic disorders, depending on an individual's genotype.
-
Vercelli, D. Discovering susceptibility genes for asthma and allergy. Nature Rev. Immunol. 8, 169-182 (2008). This review presents the current understanding of the many genes that have been implicated in asthma and allergy, including evidence that exposure to the same microbial products may have opposite effects on susceptibility to developing allergic disorders, depending on an individual's genotype.
-
-
-
-
20
-
-
0141799910
-
The regulation of immunoglobulin E class-switch recombination
-
Geha, R. S., Jabara, H. H. & Brodeur, S. R. The regulation of immunoglobulin E class-switch recombination. Nature Rev. Immunol. 3, 721-732 (2003).
-
(2003)
Nature Rev. Immunol
, vol.3
, pp. 721-732
-
-
Geha, R.S.1
Jabara, H.H.2
Brodeur, S.R.3
-
21
-
-
40049101678
-
-
Gould, H. J. & Sutton, B. J. IgE in allergy and asthma today. Nature Rev. Immunol. 8, 205-217 (2008). This review describes the complex role of IgE and its receptors in allergy and asthma, including evidence that IgE and its receptors may contribute to epitope spreading in, and therefore exacerbation of, allergic disorders.
-
Gould, H. J. & Sutton, B. J. IgE in allergy and asthma today. Nature Rev. Immunol. 8, 205-217 (2008). This review describes the complex role of IgE and its receptors in allergy and asthma, including evidence that IgE and its receptors may contribute to epitope spreading in, and therefore exacerbation of, allergic disorders.
-
-
-
-
22
-
-
0038387445
-
To respond or not to respond: T cells in allergic asthma
-
Herrick, C. A. & Bottomly, K. To respond or not to respond: T cells in allergic asthma. Nature Rev. Immunol. 3, 405-412 (2003).
-
(2003)
Nature Rev. Immunol
, vol.3
, pp. 405-412
-
-
Herrick, C.A.1
Bottomly, K.2
-
23
-
-
36148984547
-
Exoskeletons and exhalation
-
Dickey, B. F. Exoskeletons and exhalation. N. Engl. J. Med. 357, 2082-2084 (2007).
-
(2007)
N. Engl. J. Med
, vol.357
, pp. 2082-2084
-
-
Dickey, B.F.1
-
24
-
-
14944359140
-
Air pollution and allergy: You are what you breathe
-
Saxon, A. & Diaz-Sanchez, D. Air pollution and allergy: you are what you breathe. Nature Immunol. 6, 223-226 (2005).
-
(2005)
Nature Immunol
, vol.6
, pp. 223-226
-
-
Saxon, A.1
Diaz-Sanchez, D.2
-
25
-
-
40049088465
-
Dendritic cells and epithelial cells: Linking innate and adaptive immunity in asthma
-
Hammad, H. & Lambrecht, B. N. Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma. Nature Rev. Immunol. 8, 193-204 (2008).
-
(2008)
Nature Rev. Immunol
, vol.8
, pp. 193-204
-
-
Hammad, H.1
Lambrecht, B.N.2
-
27
-
-
34248530680
-
Filaggrin's fuller figure: A glimpse into the genetic architecture of atopic dermatitis
-
Sandilands, A., Smith, F. J., Irvine, A. D. & McLean, W. H. Filaggrin's fuller figure: a glimpse into the genetic architecture of atopic dermatitis. J. Invest. Dermatol. 127, 1282-1284 (2007).
-
(2007)
J. Invest. Dermatol
, vol.127
, pp. 1282-1284
-
-
Sandilands, A.1
Smith, F.J.2
Irvine, A.D.3
McLean, W.H.4
-
28
-
-
36749040998
-
Epithelium: At the interface of innate and adaptive immune responses
-
Schleimer, R. P., Kato, A., Kern, R., Kuperman, D. & Avila, P. C. Epithelium: at the interface of innate and adaptive immune responses. J. Allergy Clin. Immunol. 120, 1279-1284 (2007).
-
(2007)
J. Allergy Clin. Immunol
, vol.120
, pp. 1279-1284
-
-
Schleimer, R.P.1
Kato, A.2
Kern, R.3
Kuperman, D.4
Avila, P.C.5
-
29
-
-
33845198733
-
Lack of filaggrin expression in the human bronchial mucosa
-
Ying, S., Meng, Q., Corrigan, C. J. & Lee, T. H. Lack of filaggrin expression in the human bronchial mucosa. J. Allergy Clin. Immunol. 118, 1386-1388 (2006).
-
(2006)
J. Allergy Clin. Immunol
, vol.118
, pp. 1386-1388
-
-
Ying, S.1
Meng, Q.2
Corrigan, C.J.3
Lee, T.H.4
-
30
-
-
47349102541
-
Mite and cockroach allergens activate protease-activated receptor 2 and delay epidermal permeability barrier recovery
-
Jeong, S. K. et al. Mite and cockroach allergens activate protease-activated receptor 2 and delay epidermal permeability barrier recovery. J. Invest. Dermatol. 128, 1930-1939 (2008).
-
(2008)
J. Invest. Dermatol
, vol.128
, pp. 1930-1939
-
-
Jeong, S.K.1
-
31
-
-
33645744855
-
Proteases in parasitic diseases
-
McKerrow, J. H., Caffrey, C., Kelly, B., Loke, P. & Sajid, M. Proteases in parasitic diseases. Annu. Rev. Pathol. 1, 497-536 (2006).
-
(2006)
Annu. Rev. Pathol
, vol.1
, pp. 497-536
-
-
McKerrow, J.H.1
Caffrey, C.2
Kelly, B.3
Loke, P.4
Sajid, M.5
-
32
-
-
39449104251
-
Basophils: In the spotlight at last
-
Min, B. & Paul, W. E. Basophils: in the spotlight at last. Nature Immunol. 9, 223-225 (2008).
-
(2008)
Nature Immunol
, vol.9
, pp. 223-225
-
-
Min, B.1
Paul, W.E.2
-
34
-
-
5044238408
-
Mast-cell responses to pathogens
-
Marshall, J. S. Mast-cell responses to pathogens. Nature Rev. Immunol. 4, 787-799 (2004).
-
(2004)
Nature Rev. Immunol
, vol.4
, pp. 787-799
-
-
Marshall, J.S.1
-
35
-
-
13944277507
-
-
Galli, S. J. et al. Mast cells as 'tunable' effector and immunoregulatory cells: recent advances. Annu. Rev. Immunol. 23, 749-786 (2005). This review discusses many aspects of mast-cell biology, including mast-cell phenotypic heterogeneity and function, and the roles of mast cells as effector and potential immunoregulatory cells in innate and adaptive immune responses.
-
Galli, S. J. et al. Mast cells as 'tunable' effector and immunoregulatory cells: recent advances. Annu. Rev. Immunol. 23, 749-786 (2005). This review discusses many aspects of mast-cell biology, including mast-cell phenotypic heterogeneity and function, and the roles of mast cells as effector and potential immunoregulatory cells in innate and adaptive immune responses.
-
-
-
-
36
-
-
33344470236
-
Integrated signalling pathways for mast-cell activation
-
Gilfillan, A. M. & Tkaczyk, C. Integrated signalling pathways for mast-cell activation. Nature Rev. Immunol. 6, 218-230 (2006).
-
(2006)
Nature Rev. Immunol
, vol.6
, pp. 218-230
-
-
Gilfillan, A.M.1
Tkaczyk, C.2
-
37
-
-
33646933031
-
Molecular regulation of mast cell activation
-
Rivera, J. & Gilfillan, A. M. Molecular regulation of mast cell activation. J. Allergy Clin. Immunol. 117, 1214-1225 (2006).
-
(2006)
J. Allergy Clin. Immunol
, vol.117
, pp. 1214-1225
-
-
Rivera, J.1
Gilfillan, A.M.2
-
38
-
-
24344469627
-
Ultrastructural studies of human basophils and mast cells
-
Dvorak, A. M. Ultrastructural studies of human basophils and mast cells. J. Histochem. Cytochem. 53, 1043-1070 (2005).
-
(2005)
J. Histochem. Cytochem
, vol.53
, pp. 1043-1070
-
-
Dvorak, A.M.1
-
39
-
-
34248140140
-
Mast cell tryptases and chymases in inflammation and host defense
-
Caughey, G. H. Mast cell tryptases and chymases in inflammation and host defense. Immunol. Rev. 217, 141-154 (2007).
-
(2007)
Immunol. Rev
, vol.217
, pp. 141-154
-
-
Caughey, G.H.1
-
40
-
-
34548504097
-
Mast cell proteases
-
Pejler, G., Abrink, M., Ringvall, M. & Wernersson, S. Mast cell proteases. Adv. Immunol. 95, 167-255 (2007).
-
(2007)
Adv. Immunol
, vol.95
, pp. 167-255
-
-
Pejler, G.1
Abrink, M.2
Ringvall, M.3
Wernersson, S.4
-
41
-
-
34248183479
-
Protease-proteoglycan complexes of mouse and human mast cells and importance of their beta-tryptase-heparin complexes in inflammation and innate immunity
-
Stevens, R. L. & Adachi, R. Protease-proteoglycan complexes of mouse and human mast cells and importance of their beta-tryptase-heparin complexes in inflammation and innate immunity. Immunol. Rev. 217, 155-167 (2007).
-
(2007)
Immunol. Rev
, vol.217
, pp. 155-167
-
-
Stevens, R.L.1
Adachi, R.2
-
42
-
-
0029808816
-
The mast cell as a source of cytokines in asthma
-
Bradding, P. & Holgate, S. T. The mast cell as a source of cytokines in asthma. Ann. NY Acad. Sci. 796, 272-281 (1996).
-
(1996)
Ann. NY Acad. Sci
, vol.796
, pp. 272-281
-
-
Bradding, P.1
Holgate, S.T.2
-
43
-
-
0034987863
-
Human mast cell transcriptome project
-
Saito, H., Nakajima, T. & Matsumoto, K. Human mast cell transcriptome project. Int. Arch. Allergy Immunol. 125, 1-8 (2001).
-
(2001)
Int. Arch. Allergy Immunol
, vol.125
, pp. 1-8
-
-
Saito, H.1
Nakajima, T.2
Matsumoto, K.3
-
44
-
-
34248226331
-
Mast cells and eicosanoid mediators: A system of reciprocal paracrine and autocrine regulation
-
Boyce, J. A. Mast cells and eicosanoid mediators: a system of reciprocal paracrine and autocrine regulation. Immunol. Rev. 217, 168-185 (2007).
-
(2007)
Immunol. Rev
, vol.217
, pp. 168-185
-
-
Boyce, J.A.1
-
45
-
-
34548361747
-
Anaphylaxis: Lessons from mouse models
-
Finkelman, F. D. Anaphylaxis: lessons from mouse models. J. Allergy Clin. Immunol. 120, 506-515 (2007).
-
(2007)
J. Allergy Clin. Immunol
, vol.120
, pp. 506-515
-
-
Finkelman, F.D.1
-
46
-
-
0032968706
-
Immunologic basis of antigen-induced airway hyperresponsiveness
-
Wills-Karp, M. Immunologic basis of antigen-induced airway hyperresponsiveness. Annu. Rev. Immunol. 17, 255-281 (1999).
-
(1999)
Annu. Rev. Immunol
, vol.17
, pp. 255-281
-
-
Wills-Karp, M.1
-
47
-
-
33750519286
-
The role of the nervous system in rhinitis
-
Sarin, S., Undem, B., Sanico, A. & Togias, A. The role of the nervous system in rhinitis. J. Allergy Clin. Immunol. 118, 999-1016 (2006).
-
(2006)
J. Allergy Clin. Immunol
, vol.118
, pp. 999-1016
-
-
Sarin, S.1
Undem, B.2
Sanico, A.3
Togias, A.4
-
48
-
-
34548688890
-
Neuroimmune interactions in allergic skin diseases
-
Cevikbas, F., Steinhoff, A., Homey, B. & Steinhoff, M. Neuroimmune interactions in allergic skin diseases. Curr. Opin. Allergy Clin. Immunol. 7, 365-373 (2007).
-
(2007)
Curr. Opin. Allergy Clin. Immunol
, vol.7
, pp. 365-373
-
-
Cevikbas, F.1
Steinhoff, A.2
Homey, B.3
Steinhoff, M.4
-
49
-
-
0029853739
-
Pathophysiology and clinical presentations of cough
-
discussion S96-S97
-
Lalloo, U. G., Barnes, P. J. & Chung, K. F. Pathophysiology and clinical presentations of cough. J. Allergy Clin. Immunol. 98, S91-S96; discussion S96-S97 (1996).
-
(1996)
J. Allergy Clin. Immunol
, vol.98
-
-
Lalloo, U.G.1
Barnes, P.J.2
Chung, K.F.3
-
50
-
-
0036516361
-
Basophils in airway disease
-
MacGlashan, D. Jr, Gauvreau, G. & Schroeder, J. T. Basophils in airway disease. Curr. Allergy Asthma Rep. 2, 126-132 (2002).
-
(2002)
Curr. Allergy Asthma Rep
, vol.2
, pp. 126-132
-
-
MacGlashan Jr, D.1
Gauvreau, G.2
Schroeder, J.T.3
-
51
-
-
11144248234
-
Mast cells and basophils: Friends as well as foes in bronchial asthma?
-
Marone, G., Triggiani, M. & de Paulis, A. Mast cells and basophils: friends as well as foes in bronchial asthma? Trends Immunol. 26, 25-31 (2005).
-
(2005)
Trends Immunol
, vol.26
, pp. 25-31
-
-
Marone, G.1
Triggiani, M.2
de Paulis, A.3
-
52
-
-
44349101991
-
Immunomodulatory mast cells: Negative, as well as positive, regulators of immunity
-
Galli, S. J., Grimbaldeston, M. A. & Tsai, M. Immunomodulatory mast cells: negative, as well as positive, regulators of immunity. Nature Rev. Immunol. 8, 478-486 (2008).
-
(2008)
Nature Rev. Immunol
, vol.8
, pp. 478-486
-
-
Galli, S.J.1
Grimbaldeston, M.A.2
Tsai, M.3
-
53
-
-
42649118758
-
The master switch: The role of mast cells in autoimmunity and tolerance
-
Sayed, B. A., Christy, A., Quirion, M. R. & Brown, M. A. The master switch: the role of mast cells in autoimmunity and tolerance. Annu. Rev. Immunol. 26, 705-739 (2008).
-
(2008)
Annu. Rev. Immunol
, vol.26
, pp. 705-739
-
-
Sayed, B.A.1
Christy, A.2
Quirion, M.R.3
Brown, M.A.4
-
54
-
-
33646901630
-
The role of the mast cell in the pathophysiology of asthma
-
Bradding, P., Walls, A. F. & Holgate, S. T. The role of the mast cell in the pathophysiology of asthma. J. Allergy Clin. Immunol. 117, 1277-1284 (2006).
-
(2006)
J. Allergy Clin. Immunol
, vol.117
, pp. 1277-1284
-
-
Bradding, P.1
Walls, A.F.2
Holgate, S.T.3
-
55
-
-
36849072350
-
The mast cell and allergic diseases: Role in pathogenesis and implications for therapy
-
Brown, J. M., Wilson, T. M. & Metcalfe, D. D. The mast cell and allergic diseases: role in pathogenesis and implications for therapy. Clin. Exp. Allergy 38, 4-18 (2008).
-
(2008)
Clin. Exp. Allergy
, vol.38
, pp. 4-18
-
-
Brown, J.M.1
Wilson, T.M.2
Metcalfe, D.D.3
-
56
-
-
0037338904
-
The role of T lymphocytes in the pathogenesis of asthma
-
Larché, M., Robinson, D. S. & Kay, A. B. The role of T lymphocytes in the pathogenesis of asthma. J. Allergy Clin. Immunol. 111, 450-463 (2003).
-
(2003)
J. Allergy Clin. Immunol
, vol.111
, pp. 450-463
-
-
Larché, M.1
Robinson, D.S.2
Kay, A.B.3
-
57
-
-
34247265934
-
Airway expression of calcitonin gene-related peptide in T-cell peptide-induced late asthmatic reactions in atopics
-
Kay, A. B. et al. Airway expression of calcitonin gene-related peptide in T-cell peptide-induced late asthmatic reactions in atopics. Allergy 62, 495-503 (2007).
-
(2007)
Allergy
, vol.62
, pp. 495-503
-
-
Kay, A.B.1
-
59
-
-
36849070537
-
Cytokines and growth factors in airway remodeling in asthma
-
Doherty, T. & Broide, D. Cytokines and growth factors in airway remodeling in asthma. Curr. Opin. Immunol. 19, 676-680 (2007).
-
(2007)
Curr. Opin. Immunol
, vol.19
, pp. 676-680
-
-
Doherty, T.1
Broide, D.2
-
60
-
-
36849031788
-
Epithelium dysfunction in asthma
-
This review discusses the role of the airway epithelium and its function (and dysfunction) in the development and pathology of asthma
-
Holgate, S. T. Epithelium dysfunction in asthma. J. Allergy Clin. Immunol. 120, 1233-1244 (2007). This review discusses the role of the airway epithelium and its function (and dysfunction) in the development and pathology of asthma.
-
(2007)
J. Allergy Clin. Immunol
, vol.120
, pp. 1233-1244
-
-
Holgate, S.T.1
-
61
-
-
35649003903
-
-
Mauad, T., Bel, E. H. & Sterk, P. J. Asthma therapy and airway remodeling. J. Allergy Clin. Immunol. 120, 997-1009 (2007).
-
Mauad, T., Bel, E. H. & Sterk, P. J. Asthma therapy and airway remodeling. J. Allergy Clin. Immunol. 120, 997-1009 (2007).
-
-
-
-
62
-
-
0025807920
-
Substance P immunoreactive nerves in airways from asthmatics and nonasthmatics
-
Ollerenshaw, S. L., Jarvis, D., Sullivan, C. E. & Woolcock, A. J. Substance P immunoreactive nerves in airways from asthmatics and nonasthmatics. Eur. Respir. J. 4, 673-682 (1991).
-
(1991)
Eur. Respir. J
, vol.4
, pp. 673-682
-
-
Ollerenshaw, S.L.1
Jarvis, D.2
Sullivan, C.E.3
Woolcock, A.J.4
-
63
-
-
0031753366
-
Bronchial mucosal immunoreactivity of sensory neuropeptides in severe airway diseases
-
Chanez, P. et al. Bronchial mucosal immunoreactivity of sensory neuropeptides in severe airway diseases. Am. J. Respir. Crit. Care Med. 158, 985-990 (1998).
-
(1998)
Am. J. Respir. Crit. Care Med
, vol.158
, pp. 985-990
-
-
Chanez, P.1
-
64
-
-
0037791697
-
The role of neural inflammation in asthma and chronic obstructive pulmonary disease
-
Joos, G. F., De Swert, K. O., Schelfhout, V. & Pauwels, R. A. The role of neural inflammation in asthma and chronic obstructive pulmonary disease. Ann. NY Acad. Sci. 992, 218-230 (2003).
-
(2003)
Ann. NY Acad. Sci
, vol.992
, pp. 218-230
-
-
Joos, G.F.1
De Swert, K.O.2
Schelfhout, V.3
Pauwels, R.A.4
-
65
-
-
33747816430
-
Autonomic nervous system control of the cardiovascular and respiratory systems in asthma
-
Lewis, M. J., Short, A. L. & Lewis, K. E. Autonomic nervous system control of the cardiovascular and respiratory systems in asthma. Respir. Med. 100, 1688-1705 (2006).
-
(2006)
Respir. Med
, vol.100
, pp. 1688-1705
-
-
Lewis, M.J.1
Short, A.L.2
Lewis, K.E.3
-
66
-
-
0037198418
-
Mast-cell infiltration of airway smooth muscle in asthma
-
Brightling, C. E. et al. Mast-cell infiltration of airway smooth muscle in asthma. N. Engl. J. Med. 346, 1699-1705 (2002).
-
(2002)
N. Engl. J. Med
, vol.346
, pp. 1699-1705
-
-
Brightling, C.E.1
-
67
-
-
2542486456
-
Asthma: Mechanisms of disease persistence and progression
-
Cohn, L., Elias, J. A. & Chupp, G. L. Asthma: mechanisms of disease persistence and progression. Annu. Rev. Immunol. 22, 789-815 (2004).
-
(2004)
Annu. Rev. Immunol
, vol.22
, pp. 789-815
-
-
Cohn, L.1
Elias, J.A.2
Chupp, G.L.3
-
68
-
-
0036482387
-
Relationship of viral infections to wheezing illnesses and asthma
-
Gern, J. E. & Busse, W. W. Relationship of viral infections to wheezing illnesses and asthma. Nature Rev. Immunol. 2, 132-138 (2002).
-
(2002)
Nature Rev. Immunol
, vol.2
, pp. 132-138
-
-
Gern, J.E.1
Busse, W.W.2
-
69
-
-
84882327155
-
New insights into atopic dermatitis
-
Leung, D. Y., Boguniewicz, M., Howell, M. D., Nomura, I. & Hamid, Q. A. New insights into atopic dermatitis. J. Clin. Invest. 113, 651-657 (2004).
-
(2004)
J. Clin. Invest
, vol.113
, pp. 651-657
-
-
Leung, D.Y.1
Boguniewicz, M.2
Howell, M.D.3
Nomura, I.4
Hamid, Q.A.5
-
70
-
-
1142297465
-
Pathophysiologic mechanisms of chronic rhinosinusitis
-
Pawankar, R., Nonaka, M., Yamagishi, S. & Yagi, T. Pathophysiologic mechanisms of chronic rhinosinusitis. Immunol. Allergy Clin. North Am. 24, 75-85 (2004).
-
(2004)
Immunol. Allergy Clin. North Am
, vol.24
, pp. 75-85
-
-
Pawankar, R.1
Nonaka, M.2
Yamagishi, S.3
Yagi, T.4
-
71
-
-
17844406608
-
HLA-DR- and CD11c-positive dendritic cells penetrate beyond well-developed epithelial tight junctions in human nasal mucosa of allergic rhinitis
-
Takano, K. et al. HLA-DR- and CD11c-positive dendritic cells penetrate beyond well-developed epithelial tight junctions in human nasal mucosa of allergic rhinitis. J. Histochem. Cytochem. 53, 611-619 (2005).
-
(2005)
J. Histochem. Cytochem
, vol.53
, pp. 611-619
-
-
Takano, K.1
-
73
-
-
40049104892
-
-
Barnes, P. J. Immunology of asthma and chronic obstructive pulmonary disease. Nature Rev. Immunol. 8, 183-192 (2008).
-
Barnes, P. J. Immunology of asthma and chronic obstructive pulmonary disease. Nature Rev. Immunol. 8, 183-192 (2008).
-
-
-
-
74
-
-
0036780841
-
Regulation of mast-cell and basophil function and survival by IgE
-
Kawakami, T. & Galli, S. J. Regulation of mast-cell and basophil function and survival by IgE. Nature Rev. Immunol. 2, 773-786 (2002).
-
(2002)
Nature Rev. Immunol
, vol.2
, pp. 773-786
-
-
Kawakami, T.1
Galli, S.J.2
-
75
-
-
33745225217
-
-
Yu, M. et al. Mast cells can promote the development of multiple features of chronic asthma in mice. J. Clin. Invest. 116, 1633-1641 (2006). This paper presents evidence that mast cells can contribute to multiple features of the pathology in a mouse model of chronic asthma both by mechanisms that do or do not require the antibody (IgE and/or IgG1)-dependent activation of mast cells through the FcRγ chain shared by mast-cell FcεRI and FcγRIII.
-
Yu, M. et al. Mast cells can promote the development of multiple features of chronic asthma in mice. J. Clin. Invest. 116, 1633-1641 (2006). This paper presents evidence that mast cells can contribute to multiple features of the pathology in a mouse model of chronic asthma both by mechanisms that do or do not require the antibody (IgE and/or IgG1)-dependent activation of mast cells through the FcRγ chain shared by mast-cell FcεRI and FcγRIII.
-
-
-
-
76
-
-
41149176997
-
Allergic pulmonary inflammation in mice is dependent on eosinophil-induced recruitment of effector T cells
-
Jacobsen, E. A. et al. Allergic pulmonary inflammation in mice is dependent on eosinophil-induced recruitment of effector T cells. J. Exp. Med. 205, 699-710 (2008).
-
(2008)
J. Exp. Med
, vol.205
, pp. 699-710
-
-
Jacobsen, E.A.1
-
77
-
-
3042838551
-
The alveolar macrophage: The forgotten cell in asthma
-
Peters-Golden, M. The alveolar macrophage: the forgotten cell in asthma. Am. J. Respir. Cell Mol. Biol. 31, 3-7 (2004).
-
(2004)
Am. J. Respir. Cell Mol. Biol
, vol.31
, pp. 3-7
-
-
Peters-Golden, M.1
-
78
-
-
35348858629
-
Platelet activation during allergic inflammation
-
Kasperska-Zajac, A. & Rogala, B. Platelet activation during allergic inflammation. Inflammation 30, 161-166 (2007).
-
(2007)
Inflammation
, vol.30
, pp. 161-166
-
-
Kasperska-Zajac, A.1
Rogala, B.2
-
79
-
-
33644986351
-
+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma
-
+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma. N. Engl. J. Med. 354, 1117-1129 (2006).
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 1117-1129
-
-
Akbari, O.1
-
80
-
-
34047261246
-
Invariant natural killer T cells in asthma and chronic obstructive pulmonary disease
-
Vijayanand, P. et al. Invariant natural killer T cells in asthma and chronic obstructive pulmonary disease. N. Engl. J. Med. 356, 1410-1422 (2007).
-
(2007)
N. Engl. J. Med
, vol.356
, pp. 1410-1422
-
-
Vijayanand, P.1
-
81
-
-
17744376022
-
Anti-immunoglobulin E treatment with omalizumab in allergic diseases: An update on anti-inflammatory activity and clinical efficacy
-
Holgate, S. T., Djukanovic, R., Casale, T. & Bousquet, J. Anti-immunoglobulin E treatment with omalizumab in allergic diseases: an update on anti-inflammatory activity and clinical efficacy. Clin. Exp. Allergy 35, 408-416 (2005).
-
(2005)
Clin. Exp. Allergy
, vol.35
, pp. 408-416
-
-
Holgate, S.T.1
Djukanovic, R.2
Casale, T.3
Bousquet, J.4
-
82
-
-
0035915364
-
Effect of omalizumab on symptoms of seasonal allergic rhinitis: A randomized controlled trial
-
Casale, T. B. et al. Effect of omalizumab on symptoms of seasonal allergic rhinitis: a randomized controlled trial. J. Am. Med. Assoc. 286, 2956-2967 (2001).
-
(2001)
J. Am. Med. Assoc
, vol.286
, pp. 2956-2967
-
-
Casale, T.B.1
-
83
-
-
0037434895
-
Effect of anti-IgE therapy in patients with peanut allergy
-
Leung, D. Y. et al. Effect of anti-IgE therapy in patients with peanut allergy. N. Engl. J. Med. 348, 986-993 (2003).
-
(2003)
N. Engl. J. Med
, vol.348
, pp. 986-993
-
-
Leung, D.Y.1
-
84
-
-
7044286403
-
Apoptosis in tissue inflammation and allergic disease
-
Akdis, C. A., Blaser, K. & Akdis, M. Apoptosis in tissue inflammation and allergic disease. Curr. Opin. Immunol. 16, 717-723 (2004).
-
(2004)
Curr. Opin. Immunol
, vol.16
, pp. 717-723
-
-
Akdis, C.A.1
Blaser, K.2
Akdis, M.3
-
85
-
-
34247528494
-
Mast cell homeostasis: A fundamental aspect of allergic disease
-
Ryan, J. J. et al. Mast cell homeostasis: a fundamental aspect of allergic disease. Crit. Rev. Immunol. 27, 15-32 (2007).
-
(2007)
Crit. Rev. Immunol
, vol.27
, pp. 15-32
-
-
Ryan, J.J.1
-
86
-
-
42649137213
-
T cell trafficking in allergic asthma: The ins and outs
-
This is a comprehensive review of the molecular regulation and consequences of T-cell migration in allergic inflammation of airways
-
Medoff, B. D., Thomas, S. Y. & Luster, A. D. T cell trafficking in allergic asthma: the ins and outs. Annu. Rev. Immunol. 26, 205-232 (2008). This is a comprehensive review of the molecular regulation and consequences of T-cell migration in allergic inflammation of airways.
-
(2008)
Annu. Rev. Immunol
, vol.26
, pp. 205-232
-
-
Medoff, B.D.1
Thomas, S.Y.2
Luster, A.D.3
-
87
-
-
34548757393
-
Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B
-
Grimbaldeston, M. A., Nakae, S., Kalesnikoff, J., Tsai, M. & Galli, S. J. Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B. Nature Immunol. 8, 1095-1104 (2007).
-
(2007)
Nature Immunol
, vol.8
, pp. 1095-1104
-
-
Grimbaldeston, M.A.1
Nakae, S.2
Kalesnikoff, J.3
Tsai, M.4
Galli, S.J.5
-
88
-
-
41749090254
-
Anti-inflammatory and proresolving lipid mediators
-
Serhan, C. N., Yacoubian, S. & Yang, R. Anti-inflammatory and proresolving lipid mediators. Annu. Rev. Pathol. 3, 279-312 (2008).
-
(2008)
Annu. Rev. Pathol
, vol.3
, pp. 279-312
-
-
Serhan, C.N.1
Yacoubian, S.2
Yang, R.3
-
89
-
-
0034090602
-
Anti-inflammatory cytokines
-
Opal, S. M. & DePalo, V. A. Anti-inflammatory cytokines. Chest 117, 1162-1172 (2000).
-
(2000)
Chest
, vol.117
, pp. 1162-1172
-
-
Opal, S.M.1
DePalo, V.A.2
-
90
-
-
0031944290
-
Regulation of immune responses by TGF-β
-
Letterio, J. J. & Roberts, A. B. Regulation of immune responses by TGF-β. Annu. Rev. Immunol. 16, 137-161 (1998).
-
(1998)
Annu. Rev. Immunol
, vol.16
, pp. 137-161
-
-
Letterio, J.J.1
Roberts, A.B.2
-
91
-
-
41549169557
-
Contextual regulation of inflammation: A duet by transforming growth factor-β and interleukin-10
-
Li, M. O. & Flavell, R. A. Contextual regulation of inflammation: a duet by transforming growth factor-β and interleukin-10. Immunity 28, 468-476 (2008).
-
(2008)
Immunity
, vol.28
, pp. 468-476
-
-
Li, M.O.1
Flavell, R.A.2
-
92
-
-
0035889936
-
Human eosinophils induce mucin production in airway epithelial cells via epidermal growth factor receptor activation
-
Burgel, P. R. et al. Human eosinophils induce mucin production in airway epithelial cells via epidermal growth factor receptor activation. J. Immunol. 167, 5948-5954 (2001).
-
(2001)
J. Immunol
, vol.167
, pp. 5948-5954
-
-
Burgel, P.R.1
-
93
-
-
46249101518
-
How regulatory T cells work
-
Vignali, D. A. A., Collison, L. W. & Workman, C. J. How regulatory T cells work. Nature Rev. Immunol. 8, 523-532 (2008).
-
(2008)
Nature Rev. Immunol
, vol.8
, pp. 523-532
-
-
Vignali, D.A.A.1
Collison, L.W.2
Workman, C.J.3
-
94
-
-
33845358553
-
Pharmacogenetics and asthma: False hope or new dawn?
-
Hall, I. P. & Sayers, I. Pharmacogenetics and asthma: false hope or new dawn? Eur. Respir. J. 29, 1239-1245 (2007).
-
(2007)
Eur. Respir. J
, vol.29
, pp. 1239-1245
-
-
Hall, I.P.1
Sayers, I.2
-
95
-
-
17644388057
-
A chimeric human-cat fusion protein blocks cat-induced allergy
-
Zhu, D. et al. A chimeric human-cat fusion protein blocks cat-induced allergy. Nature Med. 11, 446-449 (2005).
-
(2005)
Nature Med
, vol.11
, pp. 446-449
-
-
Zhu, D.1
-
96
-
-
0037434920
-
Factors associated with the development of peanut allergy in childhood
-
Lack, G., Fox, D., Northstone, K. & Golding, J. Factors associated with the development of peanut allergy in childhood. N. Engl. J. Med. 348, 977-985 (2003).
-
(2003)
N. Engl. J. Med
, vol.348
, pp. 977-985
-
-
Lack, G.1
Fox, D.2
Northstone, K.3
Golding, J.4
-
97
-
-
0031303551
-
Indoor allergens and asthma: Report of the Third International Workshop
-
Platts-Mills, T. A., Vervloet, D., Thomas, W. R., Aalberse, R. C. & Chapman, M. D. Indoor allergens and asthma: report of the Third International Workshop. J. Allergy Clin. Immunol. 100, S2-S24 (1997).
-
(1997)
J. Allergy Clin. Immunol
, vol.100
-
-
Platts-Mills, T.A.1
Vervloet, D.2
Thomas, W.R.3
Aalberse, R.C.4
Chapman, M.D.5
-
98
-
-
3543050741
-
Does exposure to dogs and cats in the first year of life influence the development of allergic sensitization?
-
Ownby, D. R. & Johnson, C. C. Does exposure to dogs and cats in the first year of life influence the development of allergic sensitization? Curr. Opin. Allergy Clin. Immunol. 3, 517-522 (2003).
-
(2003)
Curr. Opin. Allergy Clin. Immunol
, vol.3
, pp. 517-522
-
-
Ownby, D.R.1
Johnson, C.C.2
-
99
-
-
18144398573
-
Physical activity and exercise in asthma: Relevance to etiology and treatment
-
Lucas, S. R. & Platts-Mills, T. A. Physical activity and exercise in asthma: relevance to etiology and treatment. J. Allergy Clin. Immunol. 115, 928-934 (2005).
-
(2005)
J. Allergy Clin. Immunol
, vol.115
, pp. 928-934
-
-
Lucas, S.R.1
Platts-Mills, T.A.2
|