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Volumn 30, Issue 3, 2010, Pages 272-278

Structure-activity relationship of flavonoids derived from medicinal plants in preventing methylmercury-induced mitochondrial dysfunction

Author keywords

Flavonoids; Methylmercury; Mitochondria; Myricetin; Toxicity

Indexed keywords

FLAVONOID; GLUTATHIONE; METHYLMERCURY; MYRICETIN; MYRICETIN 3 RHAMNOSIDE; REACTIVE OXYGEN METABOLITE; RUTOSIDE; UNCLASSIFIED DRUG;

EID: 84984588922     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etap.2010.07.003     Document Type: Article
Times cited : (69)

References (49)
  • 1
    • 0035947014 scopus 로고    scopus 로고
    • Methylmercury-mediated inhibition of 3H-d-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase
    • Allen J.W., Mutkus L.A., Aschner M. Methylmercury-mediated inhibition of 3H-d-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase. Brain Res. 2001, 902:92-100.
    • (2001) Brain Res. , vol.902 , pp. 92-100
    • Allen, J.W.1    Mutkus, L.A.2    Aschner, M.3
  • 2
    • 0026483404 scopus 로고
    • Reactive oxygen species formation as a biomarker of methylmercury and trimethyltin neurotoxicity
    • Ali S.F., LeBel C.P., Bondy S.C. Reactive oxygen species formation as a biomarker of methylmercury and trimethyltin neurotoxicity. Neurotoxicology 1992, 13:637-648.
    • (1992) Neurotoxicology , vol.13 , pp. 637-648
    • Ali, S.F.1    LeBel, C.P.2    Bondy, S.C.3
  • 3
    • 84984577456 scopus 로고    scopus 로고
    • Involvement of glutamate and reactive oxygen species in methylmercury neurotoxicity
    • Aschner M., Syversen T., Souza D.O., Rocha J.B., Farina M. Involvement of glutamate and reactive oxygen species in methylmercury neurotoxicity. Braz. J. Med. Biol. Res. 2007, 40:285-291.
    • (2007) Braz. J. Med. Biol. Res. , vol.40 , pp. 285-291
    • Aschner, M.1    Syversen, T.2    Souza, D.O.3    Rocha, J.B.4    Farina, M.5
  • 4
    • 0034256934 scopus 로고    scopus 로고
    • Methylmercury alters glutamate transport in astrocytes
    • Aschner M., Yao C.P., Allen J.W., Tan K.H. Methylmercury alters glutamate transport in astrocytes. Neurochem. Int. 2000, 37:199-206.
    • (2000) Neurochem. Int. , vol.37 , pp. 199-206
    • Aschner, M.1    Yao, C.P.2    Allen, J.W.3    Tan, K.H.4
  • 5
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 7
    • 0036177730 scopus 로고    scopus 로고
    • The three modern faces of mercury
    • Clarkson T.W. The three modern faces of mercury. Environ. Health Perspect 2002, 1(110 Suppl.):11-23.
    • (2002) Environ. Health Perspect , vol.1 , Issue.110 SUPPL. , pp. 11-23
    • Clarkson, T.W.1
  • 8
    • 0142213730 scopus 로고    scopus 로고
    • The toxicology of mercury-current exposures and clinical manifestations
    • Clarkson T.W., Magos L., Myers G.J. The toxicology of mercury-current exposures and clinical manifestations. N. Engl. J. Med. 2003, 349:1731-1737.
    • (2003) N. Engl. J. Med. , vol.349 , pp. 1731-1737
    • Clarkson, T.W.1    Magos, L.2    Myers, G.J.3
  • 9
    • 77649226819 scopus 로고    scopus 로고
    • Nanoparticulated quercetin in combating age related cerebral oxidative injury
    • Das S., Mandal A.K., Ghosh A., Panda S., Das N., Sarkar S. Nanoparticulated quercetin in combating age related cerebral oxidative injury. Curr. Aging Sci. 2008, 1:169-174.
    • (2008) Curr. Aging Sci. , vol.1 , pp. 169-174
    • Das, S.1    Mandal, A.K.2    Ghosh, A.3    Panda, S.4    Das, N.5    Sarkar, S.6
  • 11
    • 0022445670 scopus 로고
    • Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability
    • Denizot F., Lang R. Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J. Immunol. Methods 1986, 89:271-277.
    • (1986) J. Immunol. Methods , vol.89 , pp. 271-277
    • Denizot, F.1    Lang, R.2
  • 13
    • 74949138312 scopus 로고    scopus 로고
    • Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells
    • Farina M., Campos F., Vendrell I., Berenguer J., Barzi M., Pons S., Sunol C. Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells. Toxicol. Sci. 2009, 112:416-426.
    • (2009) Toxicol. Sci. , vol.112 , pp. 416-426
    • Farina, M.1    Campos, F.2    Vendrell, I.3    Berenguer, J.4    Barzi, M.5    Pons, S.6    Sunol, C.7
  • 19
    • 73549106551 scopus 로고    scopus 로고
    • Phenolic compounds prevent Alzheimer's pathology through different effects on the amyloid-beta aggregation pathway
    • Hamaguchi T., Ono K., Murase A., Yamada M. Phenolic compounds prevent Alzheimer's pathology through different effects on the amyloid-beta aggregation pathway. Am. J. Pathol. 2009, 175:2557-2565.
    • (2009) Am. J. Pathol. , vol.175 , pp. 2557-2565
    • Hamaguchi, T.1    Ono, K.2    Murase, A.3    Yamada, M.4
  • 20
    • 0028821638 scopus 로고
    • Minamata disease: methylmercury poisoning in Japan caused by environmental pollution
    • Harada M. Minamata disease: methylmercury poisoning in Japan caused by environmental pollution. Crit. Rev. Toxicol. 1995, 25:1-24.
    • (1995) Crit. Rev. Toxicol. , vol.25 , pp. 1-24
    • Harada, M.1
  • 21
    • 0022568150 scopus 로고
    • Nature, distribution and function of plant flavonoids
    • Harborne J.B. Nature, distribution and function of plant flavonoids. Prog. Clin. Biol. Res. 1986, 213:15-24.
    • (1986) Prog. Clin. Biol. Res. , vol.213 , pp. 15-24
    • Harborne, J.B.1
  • 22
    • 0032678349 scopus 로고    scopus 로고
    • Antioxidant activity of flavonol aglycones and their glycosides in methyl linoleate
    • Hopia A., Heinonen M. Antioxidant activity of flavonol aglycones and their glycosides in methyl linoleate. J. Am. Oil Chem. Soc. 1999, 76:139-144.
    • (1999) J. Am. Oil Chem. Soc. , vol.76 , pp. 139-144
    • Hopia, A.1    Heinonen, M.2
  • 24
    • 57349180534 scopus 로고    scopus 로고
    • Antioxidants in central nervous system diseases: preclinical promise and translational challenges
    • Kamat C.D., Gadal S., Mhatre M., Williamson K.S., Pye Q.N., Hensley K. Antioxidants in central nervous system diseases: preclinical promise and translational challenges. J. Alzheimers Dis. 2008, 15:473-493.
    • (2008) J. Alzheimers Dis. , vol.15 , pp. 473-493
    • Kamat, C.D.1    Gadal, S.2    Mhatre, M.3    Williamson, K.S.4    Pye, Q.N.5    Hensley, K.6
  • 25
    • 33744990187 scopus 로고    scopus 로고
    • Glutathione modulation influences methyl mercury induced neurotoxicity in primary cell cultures of neurons and astrocytes
    • Kaur P., Aschner M., Syversen T. Glutathione modulation influences methyl mercury induced neurotoxicity in primary cell cultures of neurons and astrocytes. Neurotoxicology 2006, 27:492-500.
    • (2006) Neurotoxicology , vol.27 , pp. 492-500
    • Kaur, P.1    Aschner, M.2    Syversen, T.3
  • 26
    • 0036784093 scopus 로고    scopus 로고
    • Identification of a mechanism by which the methylmercury antidotes N-acetylcysteine and dimercaptopropanesulfonate enhance urinary metal excretion: Transport by the renal organic anion transporter-1
    • Koh A.S., Simmons-Willis T.A., Pritchard J.B., Grassl S.M., Ballatori N. Identification of a mechanism by which the methylmercury antidotes N-acetylcysteine and dimercaptopropanesulfonate enhance urinary metal excretion: Transport by the renal organic anion transporter-1. Mol. Pharmacol. 2002, 62:921-926.
    • (2002) Mol. Pharmacol. , vol.62 , pp. 921-926
    • Koh, A.S.1    Simmons-Willis, T.A.2    Pritchard, J.B.3    Grassl, S.M.4    Ballatori, N.5
  • 27
    • 48749084360 scopus 로고    scopus 로고
    • Myricetin, a naturally occurring flavonoid, prevents 2-deoxy-d-ribose induced dysfunction and oxidative damage in osteoblastic MC3T3-E1 cells
    • Lee K.H., Choi E.M. Myricetin, a naturally occurring flavonoid, prevents 2-deoxy-d-ribose induced dysfunction and oxidative damage in osteoblastic MC3T3-E1 cells. Eur. J. Pharmacol. 2008, 591:1-6.
    • (2008) Eur. J. Pharmacol. , vol.591 , pp. 1-6
    • Lee, K.H.1    Choi, E.M.2
  • 31
    • 37149049048 scopus 로고    scopus 로고
    • Nutrient and methyl mercury exposure from consuming fish
    • Myers G.J., Davidson P.W., Strain J.J. Nutrient and methyl mercury exposure from consuming fish. J. Nutr. 2007, 137:2805-2808.
    • (2007) J. Nutr. , vol.137 , pp. 2805-2808
    • Myers, G.J.1    Davidson, P.W.2    Strain, J.J.3
  • 32
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal-tissues by thiobarbituric acid reaction
    • Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal-tissues by thiobarbituric acid reaction. Anal. Biochem. 1979, 95:351-358.
    • (1979) Anal. Biochem. , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 33
    • 0032737454 scopus 로고    scopus 로고
    • The role of intracellular glutathione in methylmercury-induced toxicity in embryonic neuronal cells
    • Ou Y.C., White C.C., Krejsa C.M., Ponce R.A., Kavanagh T.J., Faustman E.M. The role of intracellular glutathione in methylmercury-induced toxicity in embryonic neuronal cells. Neurotoxicology 1999, 20:793-804.
    • (1999) Neurotoxicology , vol.20 , pp. 793-804
    • Ou, Y.C.1    White, C.C.2    Krejsa, C.M.3    Ponce, R.A.4    Kavanagh, T.J.5    Faustman, E.M.6
  • 34
    • 32244448638 scopus 로고    scopus 로고
    • Determination of St. John's wort flavonoid-metabolites in rat brain through high performance liquid chromatography coupled with fluorescence detection
    • Paulke A., Schubert-Zsilavecz M., Wurglics M. Determination of St. John's wort flavonoid-metabolites in rat brain through high performance liquid chromatography coupled with fluorescence detection. J. Chromatogr. B: Analyt. Technol. Biomed. Life. Sci. 2006, 832:109-113.
    • (2006) J. Chromatogr. B: Analyt. Technol. Biomed. Life. Sci. , vol.832 , pp. 109-113
    • Paulke, A.1    Schubert-Zsilavecz, M.2    Wurglics, M.3
  • 35
    • 0033859612 scopus 로고    scopus 로고
    • Flavonoids as antioxidants
    • Pietta P.G. Flavonoids as antioxidants. J. Nat. Prod. 2000, 63:1035-1042.
    • (2000) J. Nat. Prod. , vol.63 , pp. 1035-1042
    • Pietta, P.G.1
  • 36
    • 0034980926 scopus 로고    scopus 로고
    • Effects of 2,3-dimercapto-1-propanesulfonic acid (DMPS) on tissue and urine mercury levels following prolonged methylmercury exposure in rats
    • Pingree S.D., Simmonds P.L., Woods J.S. Effects of 2,3-dimercapto-1-propanesulfonic acid (DMPS) on tissue and urine mercury levels following prolonged methylmercury exposure in rats. Toxicol. Sci. 2001, 61:224-233.
    • (2001) Toxicol. Sci. , vol.61 , pp. 224-233
    • Pingree, S.D.1    Simmonds, P.L.2    Woods, J.S.3
  • 37
    • 58149233844 scopus 로고    scopus 로고
    • Naringenin protects against cadmium-induced oxidative renal dysfunction in rats
    • Renugadevi J., Prabu S.M. Naringenin protects against cadmium-induced oxidative renal dysfunction in rats. Toxicology 2009, 256:128-134.
    • (2009) Toxicology , vol.256 , pp. 128-134
    • Renugadevi, J.1    Prabu, S.M.2
  • 38
    • 0035004114 scopus 로고    scopus 로고
    • Flavonoid antioxidants
    • Rice-Evans C. Flavonoid antioxidants. Curr. Med. Chem. 2001, 8:797-807.
    • (2001) Curr. Med. Chem. , vol.8 , pp. 797-807
    • Rice-Evans, C.1
  • 39
    • 0029888128 scopus 로고    scopus 로고
    • Structure-antioxidant activity relationships of flavonoids and phenolic acids
    • Rice-Evans C.A., Miller N.J., Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic. Biol. Med. 1996, 20:933-956.
    • (1996) Free Radic. Biol. Med. , vol.20 , pp. 933-956
    • Rice-Evans, C.A.1    Miller, N.J.2    Paganga, G.3
  • 41
    • 20444403753 scopus 로고    scopus 로고
    • Modulatory effect of glutathione status and antioxidants on methylmercury-induced free radical formation in primary cultures of cerebral astrocytes
    • Shanker G., Syversen T., Aschner J.L., Aschner M. Modulatory effect of glutathione status and antioxidants on methylmercury-induced free radical formation in primary cultures of cerebral astrocytes. Brain Res. Mol. Brain Res. 2005, 137:11-22.
    • (2005) Brain Res. Mol. Brain Res. , vol.137 , pp. 11-22
    • Shanker, G.1    Syversen, T.2    Aschner, J.L.3    Aschner, M.4
  • 42
    • 38849141961 scopus 로고    scopus 로고
    • Multifunction of myricetin on A beta: neuroprotection via a conformational change of A beta and reduction of A beta via the interference of secretases
    • Shimmyo Y., Kihara T., Akaike A., Niidome T., Sugimoto H. Multifunction of myricetin on A beta: neuroprotection via a conformational change of A beta and reduction of A beta via the interference of secretases. J. Neurosci. Res. 2008, 86:368-377.
    • (2008) J. Neurosci. Res. , vol.86 , pp. 368-377
    • Shimmyo, Y.1    Kihara, T.2    Akaike, A.3    Niidome, T.4    Sugimoto, H.5
  • 43
    • 33745016002 scopus 로고    scopus 로고
    • Postnatal methylmercury exposure induces hyperlocomotor activity and cerebellar oxidative stress in mice: dependence on the neurodevelopmental period
    • Stringari J., Meotti F.C., Souza D.O., Santos A.R., Farina M. Postnatal methylmercury exposure induces hyperlocomotor activity and cerebellar oxidative stress in mice: dependence on the neurodevelopmental period. Neurochem. Res. 2006, 31:563-569.
    • (2006) Neurochem. Res. , vol.31 , pp. 563-569
    • Stringari, J.1    Meotti, F.C.2    Souza, D.O.3    Santos, A.R.4    Farina, M.5
  • 45
    • 0038160331 scopus 로고    scopus 로고
    • Environmental exposure to mercury and its toxicopathologic implications for public health
    • Tchounwou P.B., Ayensu W.K., Ninashvili N., Sutton D. Environmental exposure to mercury and its toxicopathologic implications for public health. Environ. Toxicol. 2003, 18:149-175.
    • (2003) Environ. Toxicol. , vol.18 , pp. 149-175
    • Tchounwou, P.B.1    Ayensu, W.K.2    Ninashvili, N.3    Sutton, D.4
  • 46
    • 84984537489 scopus 로고    scopus 로고
    • Comparative study of quercetin and its two glycoside derivatives quercitrin and rutin against methylmercury (MeHg)-induced ROS production in rat brain slices
    • Wagner C., Vargas A.P., Roos D.H., Morel A.F., Farina M., Nogueira C.W., Aschner M., Rocha J.B. Comparative study of quercetin and its two glycoside derivatives quercitrin and rutin against methylmercury (MeHg)-induced ROS production in rat brain slices. Arch. Toxicol. 2010, 84:89-97.
    • (2010) Arch. Toxicol. , vol.84 , pp. 89-97
    • Wagner, C.1    Vargas, A.P.2    Roos, D.H.3    Morel, A.F.4    Farina, M.5    Nogueira, C.W.6    Aschner, M.7    Rocha, J.B.8
  • 47
    • 55749091622 scopus 로고    scopus 로고
    • Roles of biomarkers in evaluating interactions among mixtures of lead, cadmium and arsenic
    • Wang G., Fowler B.A. Roles of biomarkers in evaluating interactions among mixtures of lead, cadmium and arsenic. Tox. Appl. Pharmacol. 2008, 233:92-99.
    • (2008) Tox. Appl. Pharmacol. , vol.233 , pp. 92-99
    • Wang, G.1    Fowler, B.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.